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Research progress and challenges in stem cell therapy for diabetic foot: Bibliometric analysis and perspectives

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World Journal of Stem Cells 2024年第1期16卷 33-53页

作者： Hong-shuo Shi Xin Yuan Fang-Fang Wu xiao-Yu Li Wei-Jing Fan xiao Yang xiao-Ming Hu Guo-Bin Liu Department of Peripheral Vascular Surgery Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 250021China

BACKGROUND Stem cell therapy has shown great potential for treating diabetic foot(DF).AIM To conduct a bibliometric analysis of studies on the use of stem cell therapy for DF over the past two decades,with the aim of depicting the current global research landscape,identifying the most influential research hotspots,and providing insights for future research *** We searched the Web of Science Core Collection database for all relevant studies on the use of stem cell therapy in *** analysis was carried out using CiteSpace,VOSviewer,and R(4.3.1)to identify the most notable *** A search was conducted to identify publications related to the use of stem cells for DF treatment.A total of 542 articles published from 2000 to 2023 were *** United States had published the most papers on this *** this field,Iran’s Shahid Beheshti University Medical Sciences demonstrated the highest ***,*** from the same university has been an outstanding researcher in this *** Cell Research&Therapy is the journal with the highest number of publications in this *** main keywords were“diabetic foot ulcers,”“wound healing,”and“angiogenesis.”CONCLUSION This study systematically illustrated the advances in the use of stem cell therapy to treat DF over the past 23 *** research findings suggested that the hotspots in this field include stem cell dressings,exosomes,wound healing,and adipose-derived stem *** research should also focus on the clinical translation of stem cell therapies for DF.

关键词： Stem cells Diabetic foot Bibliometric CiteSpace VOSviewer R-bibliometrix

Achieving high carrier mobility and low lattice thermal conductivity in GeTe-based alloys by cationic/anionic co-doping

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Rare Metals 2024年第6期43卷 2784-2795页

作者： xiao-Qiang Wang xiao-Quan Hu Jun-Yan Lin Chu-Bin Li xiao-Tong Yu Qi-Yong Chen Li-Li Xi Qi-shuo Yang Han Li Ji-Ye Zhang Shuan-Kui Li Kai Guo School of Physics and Materials Science Guangzhou UniversityGuangzhou 510006China Research Center for Advanced Information Materials(CAIM) Huangpu Research&Graduate School of Guangzhou UniversitySino-Singapore Guangzhou Knowledge CityGuangzhou510555China School of Materials Science and Engineering Shanghai UniversityShanghai 200444China Materials Genome Institute Shanghai UniversityShanghai 200444China School of Mechanical and Mining Engineering University of QueenslandBrisbaneQLD 4072Australia Key Laboratory of Si-Based Information Materials&Devices and Integrated Circuits Design Department of Education of Guangdong ProvinceGuangzhou 510006China

TheⅣ-Ⅵcompound GeTe is considered as a promising alternative to the toxic PbTe for high-efficiency mid-temperature thermoelectric ***,pristine GeTe suffers from a high concentration of Ge vacancies,resulting in an excessively high hole concentration(>1×10^(21)cm^(-3)),which greatly limits its thermoelectric *** address this issue,CuBiTe_(2)alloying is introduced to increase the formation energy of Ge vacancies in GeTe,thereby inhibiting the high carrier *** carrier scattering caused by the electronegativity difference between different elements is suppressed due to the similar electronegativity of Cu and Ge atoms.A relatively high hole mobility is obtained,which ultimately leads to a high power ***,by introducing Se as an alloying element at the anionic site in GeTe,dense point defects with mass/strainfield fluctuations are *** contributes to the strengthening of phonon scattering,thereby reducing the lattice thermal conductivity from 1.44 W·m^(-1)·K^(-1)for pristine GeTe to 0.28 W·m^(-1)·K^(-1)for Ge_(0.95)Cu_(0.05)Bi_(0.05)Te_(0.9)Se_(0.15)compound at 623 K.

关键词： GeTe Carrier mobility CuBiTe_(2)alloying Lattice thermal conductivity Thermoelectric properties

Experimental Study on Vortex-Induced Vibration of Rough Risers with Coupling Interference Effect Under Side-by-Side Arrangement

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China Ocean Engineering 2024年第1期38卷 18-28页

作者： HU Ze-bo LIU Zhen LI Peng GUO Hai-yan WANG Shu-bing REN xiao-hui HOU Hao WANG Ye-shuo College of Civil Engineering and Architecture Shandong University of Science and TechnologyQingdao 266590China Qingdao Key Laboratory of Marine Civil Engineering Materials and Structures Qingdao 266590China College of Engineering Ocean University of ChinaQingdao 266100China CHEC Dredging Co. LtdShanghai 200136China

A vortex-induced vibration(VIV)experiment of rough risers with coupling interference effect under a side-by-side arrangement was carried out in a wave-current combined *** roughness of the riser was characterized by arranging different specifications of surface attachments on the surface of the *** risers with three different roughnesses were arranged side by side with smooth risers to explore the VIV response of the riser under the combined action of roughness and interference effect,and to reveal the coupling mechanism between roughness and interference *** experimental results show that,compared with that of a smooth riser,the VIV of a rough riser under the coupling interference effect has a wider"lock-in"region,and the displacement decreases more significantly at a high reduced velocity,which is more likely to excite higher-order modes and frequency *** addition,the displacement response and frequency response of the smooth riser are not significantly affected by wake interference from the rough riser,which is caused by the decrease of the wake region due to the delay of the boundary layer separation point of the rough riser.

关键词： marine riser vortex-induced vibration side-by-side arrangement roughness interference effect

双核铕与2,5-二氟苯甲酸及2,2′-联吡啶配合物的合成、晶体结构及表征

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无机化学学报 2008年第10期24卷 1621-1625页

作者：吴小说李夏首都师范大学化学系北京100037

用溶液法合成了混配配合物[Eu(2,5-DFBA)3(2,2′-bipy)]2(2,5-DFBA=2,5-二氟苯甲酸根,2,2′-bipy=2,2′-联吡啶),并测定了其晶体结构。该晶体属于三斜晶系,P1空间群。在配合物中,2个Eu3+离子被4个2,5-二氟苯甲酸根以双齿桥联和三齿桥联... 详细信息

用溶液法合成了混配配合物[Eu(2,5-DFBA)3(2,2′-bipy)]2(2,5-DFBA=2,5-二氟苯甲酸根,2,2′-bipy=2,2′-联吡啶),并测定了其晶体结构。该晶体属于三斜晶系,P1空间群。在配合物中,2个Eu3+离子被4个2,5-二氟苯甲酸根以双齿桥联和三齿桥联2种方式连接;每个Eu3+离子的配位数为9,分别与4个桥联2,5-二氟苯甲酸根的5个氧原子、1个双齿螯合2,5-二氟苯甲酸根的2个氧原子以及1个2,2′-联吡啶分子的2个氮原子配位。该配合物在紫外灯照射下发出强烈的红光,在荧光光谱的580、591、613、648和693nm处出现5条谱线,分别是由Eu3+离子的5D0→7Fj(j=0～4)跃迁产生的。

关键词：铕配合物 2,5-二氟苯甲酸晶体结构发光

Vascular endothelial growth factor/connective tissue growth factor and proteomic analysis of aqueous humor after intravitreal conbercept for proliferative diabetes retinopathy

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1816-1827页

作者： Hou-shuo Li xiao Lyu Ao Rong Yan-Long Bi Wei Xu Hong-Ping Cui Department of Ophthalmology Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Ophthalmology Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China

AIM:To investigate the role of connective tissue growth factor(CTGF)and vascular endothelial growth factor(VEGF)in the protein profile of the aqueous humor in patients with proliferative diabetic retinopathy(PDR)following intravitreal injection of ***:This study included 72 PDR patients and 8 cataract patients as *** patients were divided into 3 groups according to the intervals of 3,5,and 7d between intravitreal conbercept(IVC,0.5 mg/0.05 mL)injection and pars plana vitrectomy(PPV)*** humor samples were collected before and after IVC and PPV for VEGF and CTGF levels detected with enzyme-linked immunosorbent assay(ELISA).The differential proteomics of 10 patients who underwent PPV surgery 5d after IVC and 8 normal controls was studied,Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis were performed on the data,and the protein interaction network of 23 differential proteins was ***:Post-IVC,VEGF levels decreased and CTGF levels increased significantly in aqueous humor,with the CTGF/VEGF ratio rising significantly at all *** chromatography tandem mass spectrometry(LC-MS/MS)identified differentially expressed proteins between preand post-IVC *** and KEGG analyses revealed involvement in immune response,stress response,complement and coagulation cascades,ferroptosis,and PPAR signaling *** analysis highlighted key proteins like APOA1,C3,and transferrin(TF).ELISA assay confirmed the differential expression of proteins such as HBA1,SERPINA1,COL1A1,and ACTB,with significant changes in the IVC ***:The study demonstrates that IVC effectively reduces VEGF levels while increasing CTGF levels,thereby modifying the CTGF/VEGF ratio,and IVC significantly alters the protein profile in the aqueous humor of patients with *** analysis reveals that these changes are associated with critical biological pathways and protein interactions involved in immune respons

关键词： proliferative diabetic retinopathy conbercept vascular endothelial growth factor connective tissue growth factor proteomics

Fluorographene with Narrow Lateral Size and Thickness Distributions Prepared for Enhancing Lubrication Performance of Bentonite Grease

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1294-1302页

作者： XIANG shuo LU Peng ZHANG Qinhui xiao Bowen YANG Xin* ZHANG Peili MA Pengfei HE Yan LI Xuebin Army Logistics Academy of PLA Chongqing 401311China Naval Aeronautical University Yantai 2640003China Unit 32568 Shaoguan 512131China

Fluorographene(FG)with narrow lateral size and thickness distributions was prepared by a liquid-phase exfoliation method,based on liquid cascade *** Rtec MFT-5000 tribo-meter was used to investigate the lubricating performance of bentonite grease enhanced by the as-prepared *** results showed that the coefficient of friction and the wear volume of bentonite grease with 0.3 wt%FG were decreased by 20.4%and 44.9%,respectively,as compared to those of the base *** main reason is that FG can promote the formation of the tribo-chemical reaction film consisting of complex carbon oxide,Fe_(2)O_(3)and FeF_(3)on the friction surface,which can remarkably improve the performance of friction reduction and prevent the appearance of severe wear.

关键词： fluorographene liquid-phase exfoliation bentonite grease lubrication performance

Dissolution kinetics and reaction mechanism of Al_(2)O_(3) in molten CaF_(2)-CaO-Al_(2)O_(3) slag

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Journal of Iron and Steel Research International 2024年第4期31卷 861-869页

作者： Yao-xin Du Yan-wu Dong Zhou-hua Jiang Ganna Stovpchenko Yu-shuo Li Jun Huang Xin-wei Wang Yu-xiao Liu School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina Key Laboratory of Ecological Metallurgy of Multimetallic Mineral Northeastern UniversityShenyang 110819LiaoningChina State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819LiaoningChina E.O.Paton Electric Welding Institute of the National Academy of Science of Ukraine Kiev 03115Ukraine

The dissolution behavior of Al_(2)O_(3) in molten CaF_(2)-CaO-Al_(2)O_(3) slag,a basic slag system of electroslag remelting process,was investigated by rotating cylinder method using corundum rods to simulate Al_(2)O_(3) inclusions in *** experimental results show that the dissolution rate of Al_(2)O_(3);rods in CaF_(2)-CaO-Al_(2)O_(3) slag increases with the increase in rotating speed and temperature,and the rate-controlling step is the mass transfer in the *** dissolution rate of Al_(2)O,in CaF_(2)-CaO-Al_(2)O_(3) slag increases with the increase in the ratio of CaO to Al_(2)O_(3),which is due to the increase in dissolution driving force and the decrease in slag *** apparent activation energy of the mass transfer of AlOs in slag C is calculated to be 222.86 kJ mol^(-1).During the dissolution of Al_(2)0,inclusions in the slag,it reacts with F in liquid slag at first,then reacts with CaO to form the intermediate compounds of xCaO-yAl_(2)O_(3) system,and finally dissolves in molten *** dissolution rate of Al_(2)O_(3) inclusions in CaF_(2)-CaO-Al_(2)O_(3) slag for electroslag remelting is positively correlated with the ratio of the dissolution driving force and slag viscosity,and the correlation coeficient is 2.487×10^(-11).

关键词： Inclusion Electroslag remelting Mass transfer:Dissolution rate-Dissolution driving force

Wear resistance of TC4 by deformation accelerated plasma nitriding at 400 °C

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Journal of Central South University 2016年第11期23卷 2771-2776页

作者：朱小硕傅宇东李子峰冷科 College of Materials Science and Chemical Engineering Harbin Engineering University Harbin 150001 China Key Laboratory of Superlight Materials and Surface Technology of Ministry of Education Harbin Engineering University Harbin 150001 China

An integrated low temperature nitriding process for TC4（Ti6Al4V） has been developed and the effect on wear resistance has been investigated. Through the process of solid solution strengthening—cold deformation—nitriding at 400℃, the TC4 alloy is nitrided on surface and dispersion strengthened in bulk at the same time. The white nitriding layer is formed after some time of nitriding. The nitriding speed increases with the deformation degree. The construction was investigated by XRD and the nitride is Ti3N（2-X）. The wear test was carried out and results exhibit that the nitrided samples have better wear resistance.

关键词： TC4(Ti6Al4V) low temperature nitriding cold deformation wear resistance tribology

A seven-crystal spectrometer for high-energy resolution X-ray spectroscopy at Shanghai Synchrotron Radiation Facility

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Nuclear Science and Techniques 2024年第9期35卷 82-91页

作者： Bing-Bao Mei Liang-Xin Wang Song-Qi Gu xiao-Zhi Su shuo Zhang Yao Wei Jing-Yuan Ma Zheng Jiang Fei Song Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201800China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201204China National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230026China

A Johann-type X-ray spectrometer was successfully developed at the hard X-ray branch(in-vacuum undulator with a 24-mm periodic length)of the energy material beamline(E-line)at the Shanghai Synchrotron Radiation Facility(SSRF).This spectrometer was utilized to implement X-ray emission spectroscopy(XES),high-energy resolution fluorescence-detected X-ray absorption spectroscopy(HERFD-XAS),and resonant inelastic X-ray *** spherically bent crystals were positioned on the respective vertical 500-mm-diameter Rowland circles,adopting an area detector to increase the solid angle to 1.75%of 4πsr,facilitating the study of low-concentrate systems under complex reaction *** under the atmosphere pressure,the spectrometer covers the energy region from 3.5 to 18 keV,with the Bragg angle ranging from 73°to 86°during vertical *** offers a promised energy resolution of sub-eV(XES)and super-eV(HERFD-XAS).Generally,these comprehensive core-level spectroscopy methods based on hard X-rays at the E-line with an extremely high photon flux can meet the crucial requirements of a green energy ***,they provide substantial support for scientific advances in fundamental research.

关键词： X-ray emission spectroscopy High-energy-resolution X-ray spectrometer Johann geometry Energy materials SSRF