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Comparison of adults with attention-deficit/hyperactivity disorder versus Asperger’s disorder using the WAIS-R

Open Journal of Psychiatry 2013年第2期3卷 223-229页

作者： Yasuko Takanashi Hirobumi Mashiko shuntaro itagaki Hiromichi Ishikawa Norihiro Miyashita Shin-Ichi Niwa Fukushima Medical University School of Medicine Fukushima Japan

Objective: The present study compared results on the Wechsler Adult Intelligence Scale-Revised (WAIS-R) among adult patients with attention-deficit/hyperactivity disorder (AD/HD) and those with Asperger’s disorder (AD). Method: WAIS-R results were compared between 16 adults with AD/HD (8 men and 8 women;mean age, 33.81 years;mean full-scale IQ, 101.5) and 15 adults with AD (12 men and 3 women;mean age, 30.93 years;mean full-scale IQ, 104.6). Results: Verbal IQ was significantly higher than performance IQ in the AD group. Among various subtests, scores were the highest for similarities in the AD/HD group and for block design in the AD group. Picture completion test scores were the lowest scores obtained in both groups. A comparison of subtest scores between the AD/HD and AD groups showed scores for information to be significantly higher in the AD group than in the AD/HD group. Conclusions: Our results suggest that there are no differences in verbal IQ, performance IQ, and full-scale IQ scores (except for scores on the information subtest) among adult patients with AD/HD compared with adult patients with AD.

关键词： Attention-Deficit/Hyperactivity Disorder (AD/HD) Asperger’s Disorder (AD) Wechsler Adult Intelligence Scale-Revised (WAIS-R) Adult High-Functioning

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Milnacipran for Attention-Deficit Hyperactivity Disorder Symptoms in Adult Asperger’s Disorder

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Open Journal of Psychiatry 2014年第3期4卷 195-201页

作者： Hirobumi Mashiko Hiromichi Ishikawa shuntaro itagaki Yasuko Takanashi Norihiro Miyashita Takaaki Okano Shin-Ichi Niwa Hirooki Yabe Department of Neuropsychiatry School of Medicine Fukushima Medical University Fukushima City Japan

The efficacy of milnacipran for the treatment of ADHD symptoms in adult Asperger’s disorder patients was examined. Fifteen consecutive adult Asperger’s disorder patients with ADHD symptoms were treated with milnacipran for 8 weeks. Global Assessment of Functioning (GAF) and Conners’ Adult ADHD Rating Scales Objective Screening Version (CAARS-O-SV) were used for the assessment. The mean GAF scores in the 15 patients improved significantly. Inattention, inattention + hyperactivity/impulsivity and ADHD index in CAARS-O-SV were also significantly improved. Milnacipran might be useful for ADHD symptoms, exerting its effects by increasing serotonin and noradrenaline activities in Asperger’s disorder.

关键词： Milnacipran ADHD Asperger’s Disorder

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Newly Admitted Psychiatric Inpatients after the 3.11 Disaster in Fukushima, Japan

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Open Journal of Psychiatry 2017年第3期7卷 131-146页

作者： Masaki Hisamura Arinobu Hori Akira Wada Itaru Miura Hiroshi Hoshino shuntaro itagaki Yasuto Kunii Junya Matsumoto Hirobumi Mashiko Craig Katz Shin-Ichi Niwa Department of Emergency Medicine Saitama Medical Center Saitama Medical University Saitama Japan Department of Disaster and Comprehensive Medicine Fukushima Medical University Fukushima Japan Department of Neuropsychiatry Fukushima Medical University Fukushima Japan Departments of Psychiatry and Medical Education Icahn School of Medicine at Mount Sinai New York USA Department of Psychiatry Aizu Medical Center Fukushima Medical University Fukushima Japan

Background: After the March 2011 “triple” disaster in Japan, the residents of Fukushima Prefecture suffered from serious psychological stress. Aims: This study aimed to elucidate the influence of stressful conditions on psychiatric disorders, as reflected in new psychiatric admissions. Methods: Diagnoses and background conditions among new psychiatric admissions during the 3 months immediately after the disaster in 2011 and the corresponding time periods of 2010 and 2012 were surveyed. Results: In 2011, more patients were admitted in confusional, manic, neurasthenic, and delirious states, whereas there were fewer admissions for depression. In 2012, more admissions pertained to depression. Twenty-four percent of the new admissions in 2011 were associated with concerns about radiation contamination and hospitalization, which declined to 4% in 2012. Conclusions: The diagnoses and background conditions among new psychiatric admissions were affected by the disaster;with the influence differing according to the time elapsed after the disaster.

关键词： Depression Fear of Radiation Fukushima Disaster Manic State Psychiatric Inpatients

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Attention-Deficit/Hyperactivity Disorder in Adults with High-Functioning Pervasive Developmental Disorders in Japan

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Open Journal of Psychiatry 2014年第4期4卷 372-380页

作者： Yasuko Takanashi Hirobumi Mashiko Hirohide Yokokawa Yoko Kawasaki shuntaro itagaki Hiromichi Ishikawa Norihiro Miyashita Yasuaki Hayashi Asako Kudo Kentaro Oga Rieko Matsuura Shin-Ichi Niwa Department of Neuropsychiatry Fukushima Medical University School of Medicine Fukushima Japan Fukushima General Health and Welfare Center Fukushima Japan Department of Public Health Fukushima Medical University School of Medicine Fukushima Japan Department of General Medicine Juntendo University School of Medicine Tokyo Japan Musasino Child Development Clinic Tokyo Japan Hanawakousei Hospital Fukushima Japan Landic Nihonbashi Clinic Tokyo Japan Hoshigaoka Hospital Fukushima Japan Surugadai Nihon University Hospital Tokyo Japan Shiba Clinic Tokyo Japan

Aims: This study was designed to verify the proportion of Japanese adults with pervasive developmental disorder (PDD) who met the diagnostic criteria (other than E) for attention-deficit/hyperactivity disorder (ADHD) in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). Furthermore, we examined to what extent adults with PDD think that they exhibit ADHD symptoms. Methods: We developed an original Japanese self-report questionnaire to determine the presence or absence of 18 symptoms from the diagnostic criteria for ADHD in the DSM-IV-TR. We administered the questionnaire to 64 adults with high-functioning PDD (45 men and 19 women) and 21 adults with ADHD (10 men and 11 women), aged 18 to 59 years, with a full-scale intelligence quotient ≥75. Target patients were evaluated for ADHD by their psychiatrists. Results: Twenty-nine (45.3%) adults with PDD also had ADHD. The percentage of these adults who had over six perceived inattention symptoms from the DSM-IV-TR was 96.6%. The percentage of these adults who had over six perceived hyperactivity-impulsivity symptoms was 65.5%. Thirty-five (55.6%) adults with PDD responded that they were aware of having ADHD symptoms at the level of the relevant diagnostic criteria. Conclusions: The present study is the first to examine the frequency of objective and perceived ADHD symptoms in adults with PDD in Japan. Our results show that both objective and perceived ADHD symptoms frequently appear in a large number of adults with PDD. This suggests that it is necessary to attend to concomitant ADHD symptoms in the medical care of adults with PDD.

关键词： Adults Attention-Deficit/Hyperactivity Disorder (ADHD) High-Functioning Pervasive Developmental Disorders (PDD) Self-Report

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