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Pulmonary artery diameter ratio as a prognostic indicator of congenital diaphragmatic hernia

World Journal of Pediatric Surgery 2024年第1期7卷 20-25页

作者： Yuichiro Miyake Hiroyuki Koga Shuko Nojiri shunsuke yamada Takanori Ochi Go Miyano Geoffrey J Lane Atsuyuki Yamataka Tadaharu Okazaki Department of Pediatric General and Urogenital Surgery Juntendo University School of MedicineBunkyo-kuTokyoJapan Department of Medical Technology Innovation Center Juntendo UniversityBunkyo-ku TokyoJapan Department of Pediatric Surgery Juntendo University Urayasu HospitalUrayasuChibaJapan

Background Following on from an earlier study published in 2008 about left pulmonary artery(LPA)flow measured on serial echocardiography being strongly prognostic in left-sided congenital diaphragmatic hernia(CDH)and the ratio of LPA to right pulmonary artery(RPA)diameters being a simple and reliable indicator for commencing nitric oxide(NO)therapy,the ratio of LPA:RPA diameters(PA ratio orPAR)was hypothesized to possibly reflect cardiopulmonary stresses accompanying CDH *** Subjects with isolated left-sided CDH treated between 2007 and 2020 at a single pediatric surgical center were recruited and classified according to *** obtained retrospectively for subject demographics,clinical course,LPA/RPA diameters,and PAR were compared between survivors and *** value of PAR for optimizing the prognostic value of PA diameter data in CDH were analyzed with receiver operating characteristic(ROC)curve *** Of 65 subjects,there were 54 survivors(82.3%)and 11 non-survivors(17.7%);7 of 11 non-survivors died before surgical repair could be *** PAR for survivors(0.851±0.152)was significantly higher than for non-survivors(0.672±0.108)(p=0.0003).Mean PAR for non-survivors was not affected by surgical *** of survivors were:LPA≥2 mm(n=52 of 54;mean PAR=0.866±0.146)and RPA≥3mm(n=46 of 54;mean PAR=0.857±0.152).Non-survivors with similar LPA and RPA diameters to survivors had significantly lower mean *** curve cut-off for PAR was *** with high PAR(≥0.762)required high-frequency oscillatory ventilation/NO less than subjects with low PAR(<0.762)(p=0.0244 and p=0.0485,respectively)and subjects with high PAR stabilized significantly earlier than subjects with low PAR(1.71±0.68 days vs 3.20±0.87 days)(p<0.0001).Conclusions PAR would appear to be strongly correlated with clinical outcome in CDH and be useful for planning management of cardiopulmonary instability in CDH.

关键词： hernia congenital diameters

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L-ornithine hydrochloride ingestion increased carbohydrate oxidation but not lipid oxidation during submaximal endurance exercise following resistance exercise

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Advances in Bioscience and Biotechnology 2013年第1期4卷 81-88页

作者： Shinichi Demura Takayoshi yamada shunsuke Yamaji Masanobu Uchiyama Faculty of Medicine Fukui University Fukui Japan General Education Center Fukui National College of Technology Fukui Japan Graduate School of Natural Science & Technology Kanazawa University Kanazawa Japan Research and Education Center for Comprehensive Science Akita Prefectural University Akita Japan

This study aimed to examine the effect of L-ornithine hydrochloride ingestion on lipid oxidation during submaximal endurance exercise following resistance exercise. Ten healthy young male adults with no history of regular resistance exercise (age: 26.0 +/- 4.4) conducted resistance exercise after L-ornithine hydrochloride or placebo ingestion (0.1 g/kg). Subjects exercised for 60 min on an ergometer at 50% VO2peak 120 min after resistance exercise. Plasma ornithine concentrations measured immediately, 120min and 180min after resistance exercise in the L-ornithine hydrochloride ingestion condition were significantly greater than those in the placebo condition. No significant difference was found in serum growth hor mone concentrations between both conditions (F = 4.4, p = 0.065). Serum free fatty acid concentrations were significantly greater immediately after submaximal ergometer bicycle exercise in both conditions than those before ingestion, immediately after resistance exercise and 120min after resistance exercise (F = 43.4, p .001, 300% - 508%), but no significant difference was found between both conditions (F = 3.6, p = 0.090). A similar trend was observed in serum ketone bodies as well. Although total energy production during submaximal ergometer exercise did not significantly differ (t = 0.74, p = 0.238), a significant difference was found in energy production via carbohydrate and lipid oxidation;the former was greater in the Lornithine hydrochloride ingestion condition (t = 1.89, p = 0.046, d = 0.44, 106%), and the latter was greater in the placebo condition (t = 1.89, p = 0.046, d = 0.78%, 145%). From the above, L-ornithine hydrochloride ingestion may not affect lipid metabolism during submaximal endurance exercise following resistance exercise. It may be involved in energy production via carbohydrate oxidation with glucogenic amino acid.

关键词： L-Ornithine Hydrochloride Endurance Exercise Lipid Oxidation

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Reading impairment after neonatal hypoglycemia with parietotemporo-occipital injury without cortical blindness:A case report

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World Journal of Clinical Cases 2023年第16期11卷 3899-3906页

作者： Naoko Kurahashi shunsuke Ogaya Yuki Maki Norie Nonobe Sumire Kumai Yosuke Hosokawa Chikako Ogawa Keitaro yamada Koichi Maruyama Kiyokuni Miura Miho Nakamura Department of Pediatric Neurology Central HospitalAichi Developmental Disability CenterKasugai 480-0392AichiJapan Department of Pediatrics Nagoya University Graduate School of MedicineNagoya 466-8560AichiJapan Division of Neonatology Center for Maternal-Neonatal Care Nagoya University HospitalNagoya 466-8560AichiJapan Department of Pediatrics Tokyo Metropolitan Fuchu Medical Center for the DisabledFuchu 183-0042TokyoJapan Department of Functioning and Disability Institute for Developmental ResearchAichi Developmental Disability CenterKasugai 480-0392AichiJapan Okazaki Medical Center for Child Development Okazaki 444-0011AichiJapan

BACKGROUND Perinatal brain injury may lead to later neurodevelopmental disorders,whose outcomes may vary due to neuroplasticity in young *** neuroimaging studies have shown that the left parietotemporal area(which includes the left inferior parietal lobe)is associated with phonological awareness and decoding skills,which are essential skills for reading acquisition in ***,the literature on the effect of perinatal cerebral injury on the development of phonological awareness or decoding ability in childhood is *** SUMMARY We report the case of an 8-year-old boy who presented with reading difficulty following a perinatal injury in the parieto-temporal-occipital *** patient was born at term and was treated for hypoglycemia and seizures during the neonatal ***-weighted brain magnetic resonance imaging on postnatal day 4 revealed cortical and subcortical hyperintensities in the parieto-temporo-occipital *** the age of 8 years,physical examination was unremarkable,aside from mild *** occipital lobe injury,the patient had adequate visual acuity,normal eye movement,and no visual field ***-scale intelligence quotient and verbal comprehension index on Wechsler Intelligence Scale for Children-Fourth Edition were 75 and 90,*** assessment revealed adequate recognition of Japanese Hiragana ***,he had significantly slower reading speed in the Hiragana reading test than control *** phonological awareness test revealed significant errors(standard deviation+2.7)in the mora reversal *** Patients with perinatal brain injuries in the parietotemporal area require attention and may benefit from additional reading instructions.

关键词： Brain diseases Hypoglycemia Dyslexia Long-term care Education Case report

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The effect of L-ornithine hydrochloride ingestion on human growth hormone secretion after strength training

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Advances in Bioscience and Biotechnology 2010年第1期1卷 7-11页

作者： Shinichi Demura Takayoshi yamada shunsuke Yamaji Miho Komatsu Koji Morishita Kanazawa Universit Fukui National College of Technology Fukui University

This study aimed to examine the effect of L-ornithine hydrochloride ingestion on serum growth hormone secretion response after strength training in young men who did not regularly engage in high intensity exercise. Ten healthy young males without workout habits (age: 22.2 +/- 1.0 yr). Subjects performed biceps curl strength training after L-ornithine hydro- chloride and placebo ingestions. They participated in both of the above conditions randomly with a week interval in between. Serum growth hormone and ornithine levels were measured before L-ornithine hydrochloride or placebo ingestions and at 30 minutes after strength training. Serum growth hormone and ornithine level were measured. A change magnitude of serum growth hormone was significantly larger in the L-ornithine hydrochloride condition than in the placebo condition, and the effect size was also large (t = 1.91, p = .044, ES = .75). A significant interaction (F = 280.98, p = 0.000, ηp2 = 0.96) was found in serum ornithine and a multiple comparison test showed that it was greater in the L-ornithine hydrochloride condition. Serum growth hormone level after strength training increases by L-ornithine hydrochloride ingestion in untrained young males.

关键词： L-Ornithine Hydrochloride Growth Hormone Strength Training

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The effect of ornithine ingestion on carbohydrate metabolism during rest after acute resistance exercise in healthy young males

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Advances in Bioscience and Biotechnology 2011年第4期2卷 287-292页

作者： Koji Morishita Takayoshi yamada shunsuke Yamaji Mami Aoki Tamotsu Kitabayashi Masanobu Uchiyama Kyowa Hakko Bio Co. Ltd. Kanazawa University Fukui National College of Technology

The effect of oral L-ornithine hydrochloride (0.1 g/kg BW) on energy expenditure during a rest period from 120 to 180 min after resistance exercise was evaluated by indirect calorimetry. Healthy male subjects who have no habit of resistance training underwent resistance exercise (chest press, lat pulldown, leg press, shoulder press, leg extension, and leg curl), with 3 sets of each exercise and 10 repetitions in each set at 90-s intervals, 30 min after ingestion of ornithine or placebo. Plasma ornithine levels immediately after, and 120 and 180 min after, resistance exercise were significantly greater after ingestion of ornithine than of placebo (Treatment: F = 347.1, P p2 = 0.95;Interaction: F = 160.7, P p2 = 0.95), but no significant difference in serum growth hormone levels was observed between the two treatments (Treatment: F = 0.1, P = 0.751, ηp2 = 0.01;Time: F = 1.7, P = 0.229, ηp2 = 0.16;Interaction: F = 2.4, P = 0.155, ηp2 = 0.21). Although there was no between-treatment difference in energy expenditure during the rest period 120 to 180 min after resistance exercise (Treatment: F = 0.1, P = 0.718, ηp2 = 0.02;Time: F = 0.1, P = 0.767, ηp2 = 0.01;Interaction: F = 0.1, P = 0.112, ηp2 = 0.26), with ornithine ingestion carbohydrate oxidation was significantly greater than with placebo from 170 to 180 min after exercise (Treatment: F = 0.8, P = 0.383, ηp2 = 0.09;Time: F = 9.7, P = 0.013, ηp2 = 0.52;Interaction: F = 5.8, P = 0.039, ηp2 = 0.39). Moreover, 180 min after exercise, serum free fatty acid levels after ornithine ingestion were lower than after placebo (Treatment: F = 0.3, P = 0.602, ηp2 = 0.03;Time: F = 34.6, P p2 = 0.79;Interaction: F = 5.6, P = 0.042, ηp2 = 0.38). A similar trend in 3-hydroxybutylate was observed. In conclusion, ornithine ingestion before resistance exercise may enhance post-exercise carbohydrate oxidation without changing total energy expenditure.

关键词： Resistance Exercise Ornithine Carbohydrate Oxida-tion Oral Human

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Cecal volvulus associated with mobile cecum in Cornelia de Lange syndrome: Report of a case

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Open Journal of Pediatrics 2013年第2期3卷 96-98页

作者： Masataka Takahashi Toshihiko Watanabe Hideaki Tanaka Waka yamada Koji yamada Yasushi Fuchimoto shunsuke Nosaka Yutaka Kanamori Division of Radiology Department of Radiology National Center for Child Health and Development Tokyo Japan Division of Surgery Department of Surgical Subspecialties National Center for Child Health and Development Tokyo Japan

We report a case of cecal volvulus in an 11-year-old girl who had been diagnosed with Cornelia de Lange syndrome. She had undergone operative fundoplication several years earlier and was referred to our institute for treatment of intestinal obstruction. A severely dilated colon was detected on abdominal roentgenogram, and abdominal CT and colonic enema strongly suggested cecal volvulus. Emergency operation was performed and cecal volvulus with mobile cecum was ascertained;the volvulus was corrected and the mobile cecum was fixed to the peritoneum on the right side. Neurologically handicapped patients sometimes suffer from cecal volvulus, and patients with Cornelia de Lange syndrome are at especially high risk. Moreover, operative fundoplication promotes intestinal dilatation and it may be another risk factor for cecal volvulus.

关键词： Cecal Volvulus Cornelia de Lange Syndrome Whirl Sign

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Lithium Ion Transport Environment by Molecular Vibrations in Ion-Conducting Glasses

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Energy & Environmental Materials 2024年第3期7卷 133-142页

作者： Hiroki yamada Koji Ohara Satoshi Hiroi Atsushi Sakuda Kazutaka lkeda Takahiro Ohkubo Kengo Nakada Hirofumi Tsukasaki Hiroshi Nakajimai Laszlo Temleitner Laszlo Pusztai shunsuke Ariga Aoto Matsuo Jiong Ding Takumi Nakano Takuya Kimura Ryo Kobayashi Takeshi Usuki Shuta Tahara Koji Amezawa Yoshitaka Tateyama Shigeo Mori Akitoshi Hayashi Diffraction and Scattering Division Japan Synchrotron Radiation Research Institute(JASRI)1-1-1 KoutoSayo-choSayo-gun Hyogo 679-5198Japan Faculty of Materials for Energy Shimane University1060Nishi-Kawatsu-ChoMatsue Shimane 690-8504Japan Department of Applied Chemistry Graduate School of EngineeringOsaka Metropolitan University1-1 Gakuen-choSakaiOsaka 599-8531Japan Institute of Materials Structure Science High Energy Accelerator Research Organization(KEK)203-1 ShirakataTokai-muraNaka-gunlbaraki 319-1106Japan Graduate School of Engineering Chiba University 1-33 Yayoi-cho Inage-kuChiba 263-8522Japan Department of Materials Science Graduate School of EngineeringOsaka Metropolitan University1-1 Gakuen-choSakaiOsaka 599-8531Japan Wigner Research Centre for Physics Konkoly Thegeút 29-33 H-1121Budapest Hungary International Research Organisation of Advanced Science and Technology(IROAST) Kumamoto University2-39-1 KurokamiChuo-kuKumamoto 860-8555Japan Department of Applied Physics Nagoya Institute of TechnologyGokisoShowaNagoya 466-8555Japan Faculty of Science Yamagata University1-4-12 KojirakawaYamagata-shiYamagata 990-5860Japan Faculty of Science University of the Ryukyus1 SenbaruNishihara-choOkinawa 903-0213Japan Institute of Multidisciplinary Research for Advanced Materials Tohoku University2-1-1 KatahiraAoba-kuSendai 980-8577Japan Center for Green Research on Energy and Environmental Materials(GREEN)and International Center for Materials Nanoarchitectonics(MANA) National Institute for Materials Science(NIMS)TsukubaIbaraki 305-0044Japan

Controlling Li ion transport in glasses at atomic and molecular levels is key to realizing all-solid-state batteries,a promising technology for electric *** this context,Li_(3)PS_(4)glass,a promising solid electrolyte candidate,exhibits dynamic coupling between the Li^(+)cation mobility and the PS_(4)^(3-)anion libration,which is commonly referred to as the paddlewheel *** addition,it exhibits a concerted cation diffusion effect(i.e.,a cation-cation interaction),which is regarded as the essence of high Li ion ***,the correlation between the Li^(+)ions within the glass structure can only be vaguely determined,due to the limited experimental information that can be ***,this study reports that the Li ions present in glasses can be classified by evaluating their valence oscillations via Bader analysis to topologically analyze the chemical *** is found that three types of Li ions are present in Li_(3)PS_(4)glass,and that the more mobile Li ions(i.e.,the Li3-type ions)exhibit a characteristic correlation at relatively long distances of ***,reverse Monte Carlo simulations combined with deep learning potentials that reproduce X-ray,neutron,and electron diffraction pair distribution functions showed an increase in the number of Li3-type ions for partially crystallized glass structures with improved Li ion transport *** results show order within the disorder of the Li ion distribution in the glass by a topological analysis of their ***,considering the molecular vibrations in the glass during the evaluation of the Li ion valences is expected to lead to the development of new solid electrolytes.

关键词： electrolytes ionic conductors modeling molecular dynamics

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Relationship between Extent of Coffee Intake and Recognition of Its Effects and Ingredients

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Detection 2013年第1期1卷 1-6页

作者： Hiroki Sugiura Shinichi Demura Yoshinori Nagasawa shunsuke Yamaji Tamotsu Kitabayashi Shigeki Matsuda Takayoshi yamada Ning Xu Department of Health and Sports Sciences Kyoto Pharmaceutical University Kyoto Japan Faculty of Education and Regional Studies University of Fukui Fukui Japan Faculty of Medical Sciences University of Fukui Fukui Japan Faculty of Science Division 1 Tokyo University of Science Tokyo Japan Graduate School of Natural Science and Technology Kanazawa University Ishikawa Japan Human and Socio-Environmental Studies Kanazawa University Ishikawa Japan Junior College Gifu Shotoku Gakuen University Gifu Japan

This study examined the relationship between number of cups of coffee intake and recognition of the effects of coffee intake and its ingredients in young males and females. The subjects included 624 young people (ages 15 - 24;359 males, 265 females), who drank coffee habitually. They were classified into three groups on the basis of the number of cups of coffee consumed per day: “one cup,” “two cups,” and “over three cups.” In males, about 25% of the “over three cups” group expected “resolution of stress” from coffee, and this percentage was higher than that in the other groups. In females, about 18% of the same group had similar expectations;however, no significant group difference was found among the three groups. Few persons expected protective effects of diabetes mellitus and cancer in both genders (about 5% answer rate). About 20% of males and 18% of females in the “over three cups” group recognized the “laxative property” of coffee intake, and a significant group difference was found only in males. Even in the “one cup” group, over 77% knew that “caffeine” is an ingredient of coffee;however, few persons (under 15%) knew “poly-phenol,” which has protective effects of diabetes mellitus and cancer. In addition, no significant group difference was found in both genders. In conclusion, regardless of the coffee intake cup-number in both genders, recognition of the effects of coffee intake was low in both males and females and the recognition of effects differs by the intake cup-number in males. Only few persons knew the other ingredients in coffee apart from “caffeine.”

关键词： Coffee Number of Cups of Intake Expectation Recognition

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Ga Content Dependence of Cell Performance for Bifacial CIGS Thin Film Solar Cells

Ga Content Dependence of Cell Performance for Bifacial CIGS ...

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第十五届国际光伏科学与工程大会

作者： Yosuke Kanda shunsuke Kijima Yusuke Komiya Hiroki Ishizaki Naoomi yamada Tokio Nakada Dept.of Electrical Engineering and Electronics Aoyama Gakuin University 5-10-1Sagamihara Kanagawa 229-8558 Japan Dept.of Electrical Engineering and Electronics Aoyama Gakuin University 5-10-1Sagamihara Kanagawa 229-8558 Japan Dept.of Electrical Engineering and Electronics Aoyama Gakuin University 5-10-1Sagamihara Kanagawa 229-8558 Japan Dept.of Electrical Engineering and Electronics Aoyama Gakuin University 5-10-1Sagamihara Kanagawa 229-8558 Japan Dept.of Electrical Engineering and Electronics Aoyama Gakuin University 5-10-1Sagamihara Kanagawa 229-8558 Japan Dept.of Electrical Engineering and Electronics Aoyama Gakuin University 5-10-1Sagamihara Kanagawa 229-8558 Japan

＜正＞ Bifacial CIGS solar cell with a ZnO:Al/ZnO/CdS/CIGS/ITO/SLG structure using ITO （Indium Tin Oxide） back contacts have been fabricated. In this contribution, the details of fabrication and performance of bifacial CIGS thin film solar cells are described. The cell performance of the CIGS device was improved by optimizing Ga content in the CIGS layer. A best cell showed total area efficiencies of 12.6% and 7.4% for front and rear side illumination, respectively. This result implies that the maximum equivalent cell efficiency of 20.0% could be obtained when both sides of the bifacial device were illuminated simultaneously under AM1.5, 100 mW/cm2 conditions.

关键词： Cu (In,Ga)Se2 Bifacial Thin Film Solar Cells Transparent Conducting Oxides ITO

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化学外加剂与水泥基材料的流变特性

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混凝土世界 2009年第9期 52-63页

作者：张庆欢 shunsuke HANEHARA Kazuo yamada

化学外加剂的技术进步使得控制水泥基材料和混凝土的流动性成为现实。有研究表明,由外加剂所形成的流动性变化受到水泥自身水化及/或外加剂后吸附性的影响。本文将讨论外加剂的类型及其性能、减水机理、水泥基材料的流动性及外加剂与水... 详细信息

化学外加剂的技术进步使得控制水泥基材料和混凝土的流动性成为现实。有研究表明,由外加剂所形成的流动性变化受到水泥自身水化及/或外加剂后吸附性的影响。本文将讨论外加剂的类型及其性能、减水机理、水泥基材料的流动性及外加剂与水泥的相容性。

关键词：化学外加剂水泥基材料流变特性技术进步减水机理流动混凝土吸附性

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