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新工科视域下项目制教学在卓越工程创新人才培养中的实践探索

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华北水利水电大学学报（社会科学版） 2024年第5期40卷 103-107页

作者：王慧李长永赵洋赵顺波华北水利水电大学土木与交通学院河南郑州450045

为贯彻落实以学生为中心的目标导向工程教育理念,探讨新工科视域下卓越工程创新人才培养难题的解决方案,以土木类卓越创新人才培养为例,系统研究了以项目化教学为核心的土木专业本硕贯通培养体系的形成路径。研究表明,坚持以项目制教学... 详细信息

为贯彻落实以学生为中心的目标导向工程教育理念,探讨新工科视域下卓越工程创新人才培养难题的解决方案,以土木类卓越创新人才培养为例,系统研究了以项目化教学为核心的土木专业本硕贯通培养体系的形成路径。研究表明,坚持以项目制教学为核心,打破学生本科培养学段和研究生培养学段的壁垒、课程门类的壁垒,构建学生项目组和指导教师组双向互通的评价机制,能够在推动卓越工程创新人才培养体系与项目实施、产业科研和价值塑造的深度结合、促进工科院校在创新转型方面发挥积极作用。

关键词：新工科项目制教学卓越工程创新人才

内水渗漏软化基底对盾构隧洞衬砌管片受力性能的影响分析

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水资源与水工程学报 2024年第3期35卷 201-206,216页

作者：赵顺波崔豪何银涛杨亚彬张智晓袁林华北水利水电大学黄河流域水资源高效利用省部共建协同创新中心河南郑州450046 安阳中州供水有限公司河南安阳455000

水工盾构隧洞在运行过程中存在内水渗漏导致基底软化的风险,基底软化将对隧洞管片受力变形产生影响。依托实际水工盾构隧洞工程,构建了由管片、灌浆体和围岩组成的三维有限元数值模型,针对Ⅴ类围岩条件下因渗漏导致基底均匀和不均匀软... 详细信息

水工盾构隧洞在运行过程中存在内水渗漏导致基底软化的风险,基底软化将对隧洞管片受力变形产生影响。依托实际水工盾构隧洞工程,构建了由管片、灌浆体和围岩组成的三维有限元数值模型,针对Ⅴ类围岩条件下因渗漏导致基底均匀和不均匀软化的状况,研究了管片的受力性能变化规律。结果表明:在内外荷载作用下,管片的环向应力、竖向位移和定位销应力均随基底软化深度的增加而增大,均匀软化条件下仰拱管片出现峰值为1.88 MPa的拉应力,存在管片开裂风险;基底软化导致定位销应力增大,而管片竖向位移的变化幅度较小。研究成果可为水工盾构隧洞的安全运行监测提供科学依据。

关键词：水工盾构隧洞衬砌管片基底软化内水渗漏数值分析

Simultaneous determination of acetaminophen and oxycodone in human plasma by LC–MS/MS and its application to a pharmacokinetic study

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Journal of Pharmaceutical Analysis 2018年第3期8卷 160-167页

作者： Wei Lu shunbo zhao Meng Gong Luning Sun Li Ding Department of Pharmaceutical Analysis China Pharmaceutical University 24 Tongjiaxiang Nanjing 210009 PR China Nanjing Clinical Tech Laboratories Inc. 18 Zhilan Road Jiangning District Nanjing 211000 PR China Research Division of Clinical Pharmacology the First Affiliated Hospital Nanjing Medical University Nanjing 210029 PR China

A simple and rapid liquid chromatography-tandem mass spectrometry （LC-MS/MS） method was de- veloped and validated for simultaneous determination of acetaminophen and oxycodone in human plasma. Acetaminophen-d4 and oxycodone-d3 were used as internal standards. The challenge en- countered in the method development that the high plasma concentration level of acetaminophen made the MS response saturated while the desired lower limit of quantification （LLOQ,） for oxycodone was hard to reach was well solved. The analytes were extracted by protein precipitation using acetonitrile. The matrix effect of the analytes was avoided by chromatographic separation using a hydrophilic C18 column coupled with gradient elution. Multiple reaction monitoring in positive ion mode was performed on tandem mass spectrometer employing electrospray ion source. The calibration curves were linear over the concentration ranges of 40.0-8000 ng/mL and 0.200-40.0 ng/mL for acetaminophen and oxycodone, respectively. This method, which could contribute to high throughput analysis and better clinical drug monitoring, was successfully applied to a pharmacokinetic study in healthy Chinese volunteers.

关键词： Acetaminophen Oxycodone LC-MS/MS Human plasma Pharmacokinetics

Full－range　nonlinear　analysis　of　fatigue　behaviors　of　reinforced　concrete　structures　by　finite　element　method

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Acta Oceanologica Sinica 1994年第1期13卷 143-154页

作者： Song Yupu zhao shunbo Wang Ruimin and Li Shuyao

The offshore reinforced concrete structures are always subject to cyclic load, such as wave *** this paper a new finite element analysis model is developed to analyze the stress and strain state of reinforced concrete structures including offshore concrete structures, subject to any number of the cyclic load. On the basis of the anal ysis of the experimental data,this model simplifies the number of cycles-total cyclic strain curve of concrete as three straight line segments,and it is assumed that the stress-strain curves of different cycles in each segment are the same, thus the elastoplastic analysis is only needed for the first cycle of each segment, and the stress or strain corresponding to any number of cycles can be obtained by superposition of stress or strain obtained by the above e lastoplastic analysis based on the cyclic numbers in each *** model spends less computer time,and can obtain the stress and strain states of the structures after any number of *** endochronic-damage and ideal offshore concrete platform subject to cyclic loading are experimented and analyzed by the finite element method based on the model proposed in this paper. The results between the experiment and the finite element analysis are in good agreement,which demonstrates the validity and accuracy of the proposed model.

关键词： Reinforced concrete structures,fatigue behavior full-range nonlinear analysis,finite element method

Experimental Research on Shear Behavior of Reinforced Concrete Composite Beams Under Uniformly Distributed Load

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China Ocean Engineering 1998年第4期13卷 467-476页

作者： zhao shunbo Ass. Prof., North China Institute of Water Conservancy and Hydroelectric Power, Zhengzhou 450045, P. R. China. N. China Inst. Water Conserv./H.P. Zhengzhou 450045 China

An experimental program was carried out to study the shear behavior of the reinforced concrete composite beam (RCCB) subjected to two-phase uniformly distributed load. A total of 12 reinforced concrete composite beams were tested: 10 of them were the RCCB subjected to two-phase uniformly distributed load, the other 2 were the comparative reinforced concrete beams cast at the same time as the RCCB subjected to one-phase uniformly distributed load. The interface of precast unit and recast concrete was natural and rough. The test range of the main composite factors: the ratio of precast section depth to composite section depth was from 0.35 to 0.65, the ratio of first-phase load moment to precast section ultimate bearing moment was from 0.25 to 0.65. Based on the test results, the stresses of the longitudinal reinforcements and stirrups, the load-bearing properties of the interface, the crack state and the failure characteristics of the RCCB under uniformly distributed load are discussed. The effects of the stirrups, the concrete strength and the composite factors on the shear resistance of the RCCB are analyzed, and the method for evaluating the shear resistance of the RCCB is proposed.

关键词： reinforced concrete composite beam shear resistance composite factor mechanism of failure

钢纤维混凝土焊钉-橡胶连接件受剪承载力试验研究

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建筑结构学报 2022年第2期43卷 207-214页

作者：刘世明王辰旭李晓克李尚宇赵顺波华北水利水电大学土木与交通学院河南郑州450045 华北水利水电大学河南省生态建材工程国家联合实验室河南郑州450045 长安大学旧桥检测与加固技术交通行业重点实验室陕西西安710064

为建立钢-混凝土组合结构桥梁使用的钢纤维混凝土(SFRC)焊钉-橡胶连接件受剪承载力设计计算方法,设计并制作了18组54个SFRC焊钉-橡胶连接件,通过单调加载与循环加载推出试验,研究了混凝土强度、焊钉直径、钢纤维体积掺量、橡胶套筒高度... 详细信息

为建立钢-混凝土组合结构桥梁使用的钢纤维混凝土(SFRC)焊钉-橡胶连接件受剪承载力设计计算方法,设计并制作了18组54个SFRC焊钉-橡胶连接件,通过单调加载与循环加载推出试验,研究了混凝土强度、焊钉直径、钢纤维体积掺量、橡胶套筒高度及厚度、加载模式等对其受剪承载力的影响规律。基于准牛顿法进行非线性拟合,提出了SFRC焊钉-橡胶连接件受剪承载力计算式。研究结果表明:焊钉-橡胶连接件受剪承载力随SFRC强度增大而增加,且增速呈变缓趋势;受剪承载力与焊钉杆截面面积大致呈线性增加关系,而随着橡胶套筒相对截面面积的增大而降低;钢纤维体积掺量不大于0.8%时,其对受剪承载力提升显著,随后增速变缓;加载模式对受剪承载力及破坏模式的影响不大;橡胶套筒可有效降低焊钉抗剪刚度并显著提高其变形性能。所提SFRC焊钉-橡胶连接件受剪承载力计算式可适用于SFRC强度等级CF30~CF60、焊钉直径13~25 mm、钢纤维体积掺量0~1.6%、橡胶套筒厚度不超过焊钉直径的1/2.6的SFRC焊钉-橡胶连接件设计。

关键词：组合结构桥梁焊钉-橡胶连接件钢纤维混凝土(SFRC) 推出试验受剪承载力

Automatic modeling algorithm of stochastic error for inertial sensors

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Control Theory and Technology 2024年第1期22卷 81-91页

作者： Luodi zhao Long zhao School of Automation Science and Electrical Engineering Beihang UniversityBeijing100191China Digital Navigation Center Beihang UniversityBeijing100191China Science and Technology on Aircraft Control Laboratory Beihang UniversityBeijing100191China

This paper proposes an automatic algorithm to determine the properties of stochastic processes and their parameters for inertial error. The proposed approach is based on a recently developed method called the generalized method of wavelet moments (GMWM), whose estimator was proven to be consistent and asymptotically normally distributed. This algorithm is suitable mainly (but not only) for the combination of several stochastic processes, where the model identification and parameter estimation are quite difficult for the traditional methods, such as the Allan variance and the power spectral density analysis. This algorithm further explores the complete stochastic error models and the candidate model ranking criterion to realize automatic model identification and determination. The best model is selected by making the trade-off between the model accuracy and the model complexity. The validation of this approach is verified by practical examples of model selection for MEMS-IMUs (micro-electro-mechanical system inertial measurement units) in varying dynamic conditions.

关键词： GMWM Stochastic process Inertial sensor Sensor calibration Error model Allan variance

Meeting the challenges of invasive alien species

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National Science Review 2024年第3期11卷 296-298页

作者： Weijie zhao NSR news

The Xinjiang Uygur Autonomous Region of China is famous for its tomato production. Abundant sunshine, large day–night temperature difference and the abundant irrigation by snowmelt from the Tianshan Mountains produce...

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Ling-Ling Chen: RNA has its own features;don't study it as a protein

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National Science Review 2024年第2期11卷 301-305页

作者： Weijie zhao NSR

Non-coding RNA(ncRNA) has been a very active research area over the past 30 years. From small nc RNA – the discovery of RNA interference won the lead researchers the Nobel Prize, to long ncRNA(lncRNA), which has attracted much attention in recent years, various nc RNAs participate in all kinds of biological processes and show a variety of biomedical application prospects.

关键词： RNA