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Transarterial radioembolization with Yttrium-90:current status and future prospects

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Gastroenterology Report 2020年第2期8卷 164-165,I0003页

作者： Hua-Yu yang Bao Jin Gang Xu Le-Jia Sun shun-Da Du yi-Lei Mao Department of Liver Surgery Peking Union Medical College(PUMC)HospitalPUMC&Chinese Academy of Medical Sciences(CAMS)BeijingP.R.China

In recent years,transarterial radioembolization(TARE)with Yttrium-90(Y90)has emerged as a technique for treating malignant neoplasms in the *** with other locoregional therapies,such as transarterial chemoembolization(TACE),patients who underwent TARE with Y90 have higher tumor response rates and better ***,no significant treatment-related complications or treatment-related deaths have been reported[1].We here review the clinical application of TARE and its associated issues.

关键词： neoplasms arterial treatment 现状及未来

Clinical Observations on Acupuncture Treatment of Ulcerative Colitis

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Journal of Acupuncture and Tuina Science 2003年第2期1卷 18-20页

作者： yang shun-yi Guangzhou University of Traditional Chinese Medicine Guangdong 510405 China

Purpose To observe the curative effect of acupuncture on ulcerative *** and Results Sixty-two patients with ulcerative colitis were treated mainly by needle-warming moxibustion at Lower He-Sea points and Front-mu points, with the cooperation of syndomic differentiation-based selection of acupoints and oral administration of patent Chinese medicine. After treatment the total effective rate was 91.94% and T cell subgroups returned nearly to *** This treatment method can help the internal environment of human immune system to tend to balance. Key Words Colitis - Ulcerative - Acupuncture-moxibustion - T-lymphocyte Author: yang shun-yi(1941-), male, doctor

关键词： Colitis Ulcerative Acupuncture-moxibustion T-lymphocyte

Solvent polarity-induced photoluminescence enhancement (SPIPE): A method enables several-fold increase in quantum yield of silicon nanoparticles

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Nano Research 2019年第2期12卷 315-322页

作者： Xiao-Bin Shen Bin Song Bei Fang Xiao Yuan You-Yong Li shun-yi Wang shun-Jun Ji Yao He Laboratory of Nanoscale Biochemical Analysis Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Institute of Functional Nano and Soft Materials (FUNSOM) and Collaborative Innovation Center of Suzhou Nano Science and Technology (NANO-CIC) Soochow University Suzhou 215123 China Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 China

Fluorescent silicon nanoparticles (SiNPs) bring exciting opportunities for long-awaited silicon-based optical application, while intrinsic indirect band gap of silicon severely limits photoluminescent quantum yield (PLQY) of SiNPs. To address this critical issue, we herein demonstrate a facile and general method, Le., solvent polarity-induced photoluminescence enhancement (SPIPE)1 yielding several-fold increase in quantum yield (QY) of SiNPs. Typically, different kinds of 4-substituented-1,8-naphthalic anhydride molecules, Le., 4-Br-1,8-naphthalic anhydride (BNA)1 4-triphenylamino-1,8-naphthalic anhydride (TPNA)1 and 4-dimethylamino-1,8-naphthalic anhydride (DMNA)1 are rationally designed and synthesized, which serve as surface ligands for the production of BNA-, TPNA-, and DMNA-capped small-sized (diameter:- 3.8-5.8 nm) SiNPs with QY of^8%,~15%,~16%, respectively. Of particular significance, QY of the resultant SiNPs could be greatly enhanced from^10% to^50% through the SPlPE strategy. Taken together with the theoretical calculation and the results of time-correlated single photon counting, we reveal that actived excited-state charge transfer interactions between surface-covered ligand and silicon oxide coating would be responsible for the observed QY enhancement. Moreover, other five kinds of solvents (i.e., methanol, isopropanol, dimethyl sulfoxide, N,N-dimethylformamide, and acetonitrile) are further employed for the SiNPs treatment, and similar improvement of QY values are observed, convincingly demonstrating the universal evidence of SPIPE of the SiNPs.

关键词： silicon nanoparticles quantum yield fluorescent surface ligand solvent polarity

Efficient tensor decomposition method for noncircular source in colocated coprime MIMO radar

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Chinese Physics B 2020年第5期29卷 333-345页

作者： Qian-Peng Xie Xiao-yi Pan shun-Ping Xiao National University of Defense Technology Changsha 410073China

An effective method via tensor decomposition is proposed to deal with the joint direction-of-departure(DOD)and direction-of-arrival(DOA)estimation of noncircular sources in colocated coprime MIMO *** decomposing the transmitter and receiver into two sparse subarrays,noncircular property of source can be used to construct new extended received signal model for two sparse *** new received model can double the virtual array aperture due to the elliptic covariance of imping sources is *** further exploit the multidimensional structure of the noncircular received model,we stack the subarray output and its conjugation according to mode-1 unfolding and mode-2 unfolding of a third-order tensor,***,the corresponding extended tensor model consisted of noncircular information for DOA and DOD can be ***,the higher-order singular value decomposition technique is utilized to estimate the accurate signal subspace and angular parameter can be automatically paired via the rotational invariance ***,the ambiguous angle can be eliminated and the true targets can be achieved with the aid of the coprime ***,a closed-form expression for the deterministic CRB under the NC sources scenario is also *** results verify the superiority of the proposed estimator.

关键词： colocated coprime MIMO radar noncircular signal tensor decomposition DOD and DOA estimation

A Review on Wireless Mesh Networks

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南京邮电大学学报（自然科学版） 2010年第1期30卷 48-58页

作者： TAN Ling ZHANG shun-yi College of Software Nanjing University of Posts and Telecommunications Nanjing 210003 China College of Information and Control Nanjing University of Information Science ＆ Technology Nanjing 210044 China

Wireless mesh networks (WMNs) are new kind of networking technology which facilitate the extension of wireless local area networks into wide areas and have emerged as a key technology for next-generation wireless *** to the advantages of WMNs over other wireless networks,they are now a promising approach for future network *** applications range from home broadband Internet access and community networking to wireless metropolitan area ***,the considerable efforts in academic range from network architecture,network capacity,layered communication protocols,security,cross-layer design,*** many technical challenges exist in designing affordable,reliable,and sustainable WMNs *** order to provide a better understanding of these challenges,this paper presents a detailed investigation of current technologies for WMNs,and it will help to guide and refocus future works in this area.

关键词：计算机网络 WMNs 网络安全网络协议

手性金属-有机框架二维材料的液相色谱拆分性能研究

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化学试剂 2025年第1期47卷 17-25页

作者：王雪萍高顺秋李毅洁杨梅芳龙怡幸袁黎明云南师范大学化学化工学院云南昆明650500

二维金属-有机框架材(2D-MOFs)具有大比表面积、厚度小、活性位点充分暴露、传质阻力小等优点,将其用作高效液相色谱(HPLC)固定相理论上可以增加色谱柱的塔板数,进而提高其分离效能,在手性分离领域展现出独特的应用价值。将手性分子L-... 详细信息

二维金属-有机框架材(2D-MOFs)具有大比表面积、厚度小、活性位点充分暴露、传质阻力小等优点,将其用作高效液相色谱(HPLC)固定相理论上可以增加色谱柱的塔板数,进而提高其分离效能,在手性分离领域展现出独特的应用价值。将手性分子L-羟基脯氨酸和D-(+)-葡萄糖分别修饰到NH_(2)-Ni/Co MOFs和Zn-NH_(2)-BDC MOFs两种2D-MOFs上,制备二维手性金属-有机框架纳米片(2D-CMOFs),再将Zn-NH_(2)-BDC-D-(+)-葡萄糖和NH_(2)-Ni/Co-L-羟基脯氨酸通过“网包法”固载在硅胶表面制备手性固定相。实验表明:19种手性药物和5种位置异构体被NH_(2)-Ni/Co-L-羟基脯氨酸手性色谱柱拆分开,基线分离了6种手性药物和3种位置异构体;10种手性药物和3种位置异构体被Zn-NH_(2)-BDC-D-(+)-葡萄糖色手性谱柱拆分开;且两个手性柱都具有良好的重复性。

关键词：手性分离高效液相色谱二维手性金属-有机框架材料手性固定相手性化合物

Prediction of neoantigens and their application in cancer treatment

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Hepatobiliary & Pancreatic Diseases International 2018年第6期17卷 483-484页

作者： Bao Jin ying-yi Wang shun-Da Du Department of Liver Surgery Peking Union Medical College (PUMC) Hospital Chinese Academy of Medical Sciences and PUMC Department of Medical Oncology Peking Union Medical College (PUMC) Hospital Chinese Academy of Medical Sciences and PUMC

Tumor antigens can be divided into tumor-associated antigens and tumor-specific antigens according to their specificity. Tumorassociated antigens are not unique to tumor cells, and can also be synthesized in small amounts by normal cells. Tumor-specific antigens, also called neoantigens, are formed by peptides that are entirely absent from the normal human genome [1]. Neoantigens are

关键词： Prediction of neoantigens and their application in cancer treatment

THE DYNAMICAL BEHAVIOR OF NON-SMOOTH SYSTEM WITH IMPULSIVE CONTROL STRATEGIES

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International Journal of Biomathematics 2012年第3期5卷 297-313页

作者： YUAN-shun TAN JU-HUA LIANG SAN-yi TANG Department of Mathematics and Physics Chongqing Jiaotong University Chongqing 400074 P. R. China College of Mathematics and Information Science Shaanxi Normal University Xi'an 710062 P. R. China

Non-smooth system including impulsive strategies at both fixed and unfixed times are analyzed. For the model with fixed impulsive effects, the global stability of pest eradi- cation periodic solution and the dominance of dynamic behavior are investigated. This indicates that the model with fixed moments has the potential to protect the natural enemies from extinction, but under some conditions may also serve to extinction of the pest. The second model is constructed according to the practices of IPM, that is, when the pest population reaches the economic injury level, a combination of biological, cultural, and chemical tactics that reduce pests to tolerable levels is used. Numerical investigations imply that there are several different types of periodic solutions and their maximum amplitudes are always less than the given economic threshold. The results also show that the time series at which the IPM strategies are applied are quite complex, which means that the application and realization of IPM in practice are very difficult.

关键词： Dominance non-smooth system impulsive control strategies integrated pest management global stability.

Electrospun N-halamine/ZnO-based platform eradicates bacteria through multimodal antimicrobial mechanism of action

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Rare Metals 2023年第1期42卷 222-233页

作者： Hui-Hui Qu Cong Wang yi-Xuan Guo Zi-ying Zhao Long Qiao Jie-Bing yang Hai-Xia Wu Quan-shun Li Alideertu Dong College of Chemistry and Chemical Engineering Engineering Research Center of Dairy Quality and Safety Control TechnologyMinistry of EducationInner Mongolia UniversityHohhot010021China Center of Experimental Instrument School of Food Science and TechnologyDalian Polytechnic UniversityDalian116034China Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education School of Life SciencesJilin UniversityChangchun130012China

The emergence and prevalence of antibiotic-resistant bacteria demands powerful antibacterial tactics to combat infectious *** combinational therapy based on synergistic hybrid antibacterial materials is a promising approach to realize effective sterilization through the rational integration of distinct bactericides into one compact *** this work,we constructed a microfiber-based antibacterial platform(PAM-Cl/ZnO MFs)by electrospinning N-halamine polymers(PAM-Cl)loaded with zinc oxide(ZnO)*** as-designed PAM-Cl/ZnO MFs inherited the intrinsic antibacterial effects of both PAM-Cl microfibers(PAM-Cl MFs)and ZnO microfibers(ZnO MFs),and the material exhibited enhanced synergistic antibacterial performance against Staphylococcus aureus(***)and Escherichia coli(***)in *** bactericidal effect was multimodal and included contact killing based on the N-Cl bond of N-halamine,multiple-release killing,such as reactive oxygen species(ROS)under light irritation,and Zn^(2+)and Cl^(+)acting as antibacterial ***,PAM-Cl/Zno MFs worked on inactivate bacteria even under harsh temperatures and atmospheric ***,PAM-Cl/ZnO MFs exhibited good biocompatibility and performed outstanding acceleration of wound healing with in vivo mouse skin defect models using *** work advances the design of antibacterial hybrid materials with the potency to eradicate bacteria in biological systems in multiple settings through the superiority of multimodal synergistic therapy.

关键词： N-halamine ZnO nanoparticles Electrospinning Synergistic antibacterial therapy Various scenarios