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Privacy-Preserving Federated Mobility Prediction with Compound Data and Model Perturbation Mechanism

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China Communications 2024年第3期21卷 160-173页

作者： Long Qingyue Wang Huandong Chen Huiming Jin Depeng Zhu lin Yu li li Yong Beijing National Research Center for Information Science and Technology(BNRist) Department of Electronic EngineeringTsinghua UniversityBeijing 100084China China Mobile Research Beijing 100032China

Human mobility prediction is important for many ***,training an accurate mobility prediction model requires a large scale of human trajectories,where privacy issues become an important *** rising federated learning provides us with a promising solution to this problem,which enables mobile devices to collaboratively learn a shared prediction model while keeping all the training data on the device,decoupling the ability to do machine learning from the need to store the data in the ***,existing federated learningbased methods either do not provide privacy guarantees or have vulnerability in terms of privacy *** this paper,we combine the techniques of data perturbation and model perturbation mechanisms and propose a privacy-preserving mobility prediction algorithm,where we add noise to the transmitted model and the raw data collaboratively to protect user privacy and keep the mobility prediction *** experimental results show that our proposed method significantly outperforms the existing stateof-the-art mobility prediction method in terms of defensive performance against practical attacks while having comparable mobility prediction performance,demonstrating its effectiveness.

关键词： federated learning mobility prediction privacy

Advanced System-Level Model Reduction Method for Multi-Converter DC Power Systems

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CSEE Journal of Power and Energy Systems 2024年第4期10卷 1550-1562页

作者： lin Zhu Xueshen Zhao Xialin li li Guo Bo Zhao Zhanfeng Deng Hao Lu Chengshan Wang the Key Laboratory of Smart Grid of Ministry of Education Tianjin UniversityTianjin 300072China the Research Institute of State Grid Zhejiang Electric Power Co. Ltd.Hangzhou 310014China the State Grid Global Energy Interconnection Research Institute Beijing 102209China

For dynamic stability analysis and instability mechanism understanding of multi-converter medium voltage DC power systems with droop-based double-loop control,an advanced system-level model reduction method is *** this method,mathematical relationships of control parameters(e.g.,current and voltage control parameters)between the system and its equivalent reduced-order model are ***,open-loop and closed-loop equivalent reduced-order models of current control loop considering dynamic interaction among converters are *** instability mechanism(e.g.,unreasonable current control parameters)of the system can be revealed *** guidance for adjustment of current control parameters can also be ***,considering dynamic interaction of current control among converters,open-loop and closed-loop equivalent reduced-order models of voltage control loop are *** frequency and damping factor of DC bus voltage in a wide oscillation frequency range(e.g.,10–50 Hz)can be evaluated *** importantly,accuracy of advanced system-level model reduction method is not compromised,even for MVDC power systems with inconsistent control parameters and different number of ***,experiments in RT-BOX hardware-in-the-loop experimental platform are conducted to validate the advanced system-level model reduction method.

关键词： Closed-loop reduced-order model instability mechanism open-loop reduced-order model stability analysis system-level model reduction method

Filtration performance and modeling of granular bed for dust removal from coal pyrolytic vapors

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Chinese Journal of Chemical Engineering 2024年第1期65卷 35-42页

作者： Shuaiqiang Yang lin Du Guangchao Ding Runguo liu Wenli Song Songgeng li State Key Laboratory of Multiphase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Petrochemical Engineering Yan’an Vocational and Technical CollegeYan’an 716000China Sino-Danish College University of Chinese Academy of SciencesBeijing 100049China

Dust removal from pyrolytic vapors at high temperatures is an obstacle to the industrialization of the coal pyrolysis *** this work,a granular bed with expanded perlites as filtration media was designed and integrated into a 10 t·d^(–1)coal pyrolysis *** testing results showed that around 97.56%dust collection efficiency was *** a result,dust content in tar was significantly *** pressure drop of the granular bed maintained in the range of 356 Pa to 489 *** dust size in the effluent after filtration exhibited a bimodal distribution,which was attributed to the heterogeneity of the dust *** effects of filtration bed on pyrolytic product yields were also discussed.A modified filtration model based on the macroscopic phenomenological theory was proposed to describe the performance of the granular *** computation results were well agreed with the experimental data.

关键词： Granular bed filtration Dust removal Pyrolysis Filtration Fixed-bed

Severe pediatric COVID‑19:a review from the clinical and immunopathophysiological perspectives

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World Journal of Pediatrics 2024年第4期20卷 307-324页

作者： Yi‑Kan Sun Can Wang Pei‑Quan lin Lei Hu Jing Ye Zhi‑Gang Gao Ru lin Hao‑Min li Qiang Shu li‑Su Huang lin‑Hua Tan Children's Hospital Zhejiang University School of MedicineHangzhou 310052China The Second Affiliated Hospital Zhejiang University School of MedicineHangzhou 310030China Surgical Intensive Care Unit Children’s HospitalZhejiang University School of MedicineHangzhou 310052China Department of General Surgery Children’s HospitalZhejiang University School of MedicineHangzhou 310052China Department of Cardiopulmonary and Extracorporeal life Support Children’s HospitalZhejiang University School of MedicineHangzhou 310052China Clinical Data Center Children’s HospitalZhejiang University School of MedicineHangzhou 310052China Department of Cardiac Surgery Children’s HospitalZhejiang University School of MedicineHangzhou 310052China National Clinical Research Center for Child Health Children’s HospitalZhejiang University School of MedicineHangzhou 310052China Department of Infectious Diseases Children’s HospitalZhejiang University School of MedicineHangzhou 310052China

Background Coronavirus disease 2019(COVID-19)tends to have mild presentations in ***,severe and critical cases do arise in the pediatric population with debilitating systemic impacts and can be fatal at times,meriting further attention from ***,the intricate interactions between the pathogen virulence factors and host defense mechanisms are believed to play indispensable roles in severe COVID-19 pathophysiology but remain incompletely *** sources A comprehensive literature review was conducted for pertinent publications by reviewers independently using the PubMed,Embase,and Wanfang *** keywords included“COVID-19 in children”,“severe pediatric COVID-19”,and“critical illness in children with COVID-19”.Results Risks of developing severe COVID-19 in children escalate with increasing numbers of co-morbidities and an unvaccinated *** respiratory distress stress and necrotizing pneumonia are prominent pulmonary manifestations,while various forms of cardiovascular and neurological involvement may also be *** immunological processes are implicated in the host response to COVID-19 including the type I interferon and inflammasome pathways,whose dysregulation in severe and critical diseases translates into adverse clinical *** inflammatory syndrome in children(MIS-C),a potentially life-threatening immune-mediated condition chronologically associated with COVID-19 exposure,denotes another scientific and clinical conundrum that exemplifies the complexity of pediatric *** the considerable dissimilarities between the pediatric and adult immune systems,clinical trials dedicated to children are lacking and current management recommendations are largely adapted from adult *** Severe pediatric COVID-19 can affect multiple organ *** dysregulated immune pathways in severe COVID-19 shape the disease course,epitomize the vast functional diversity of the

关键词： Immunopathophysiology MIS-C Pediatric critical care Severe pediatric COVID-19

RIOK1 synergizes with TRIP13 by regulating the E2F-Rb signaling pathway to promote the proliferation of esophageal cancer cells

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Genes & Diseases 2024年第3期11卷 55-58页

作者： Chengyu li Deyuan Pan Wan lin Danxia Deng Yingxin Zhou Hui Zhao Feng Pan liyan Xu Enmin li lin Long The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area Department of Biochemistry and Molecular BiologyShantou University Medical CollegeShantouGuangdong 515041China Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology Institute of Oncologic PathologyShantou University Medical CollegeShantouGuangdong 515041China Institute of Basic Medical Science Cancer Research CenterShantou University Medical CollegeShantouGuangdong 515041China Clinical Research Center Shantou Central HospitalShantouGuangdong 515041China

Esophageal cancer is one of the leading causes of cancer death in the world,with approximately half of the new cases occurring in China every year.^(1)Esophageal squamous cell carcinoma(ESCC)is the main subtype,accounting for more than 90%,and the five-year survival rate is less than 10%.Using large-scale genome analysis,many driver mutations and key pathways associated with ESCC have been ***,these genomic signatures have not improved the clinical management of EscC patients,or established effective targeted therapy.^(2)Esophageal cancer still lacks representative molecular markers.

关键词： cancer esophageal Esophageal

Portable hydrogel-based tri-channel fluorescence sensor array for visual detection of multiple explosives

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Nano Research 2024年第7期17卷 6483-6492页

作者： Wenxing Gao Wenfeng liu Saijin Huang lin Wang Yingying Jian Yutong li Weiwei Wu li Shang State Key Laboratory of Solidification Processing School of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi'an 710072China School of Advanced Materials and Nanotechnology Xidian UniversityXi'an 710126China Honors College Northwestern Polytechnical UniversityXi'an 710119China

The identification and detection of various types of explosives are essential for human health and environmental ***-based sensing approach offers significant advantages in detecting multi-analytes simultaneously,thereby holding great potential in identifying multiple ***,we report a tri-channel fluorescence array composed of three distinct fluorescence probes based on gold nanoclusters and nicotinamide adenine dinucleotide with well-separated emission *** the specific interactions of explosives with different fluorescent probes and the yielded response patterns,seven explosives can be successfully distinguished with 100%*** particular,the sensor array exhibits excellent performance in the quantitative analysis of individual explosive and the differentiation of multiple explosive *** facilitate the field detection towards practical application,the tri-channel fluorescence array was further integrated with polymer *** fabricated portable hydrogel-based array sensors can not only visually identify seven different explosives by their distinct fluorescence color change,but also enable quantitative detection based on linear discriminant analysis(LDA)together with a *** study illustrates the great potential of hydrogel-based fluorescence sensor array as robust sensors for explosives,which also holds significant promise for the development of portable explosive devices towards practical application.

关键词： sensor array gold nanoclusters explosives fluorescence hydrogels

Sequential reactant water management by complementary multisite catalysts for surpassing platinum hydrogen evolution activity

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Nano Research 2024年第3期17卷 1232-1241页

作者： Yu lin Defang Ding Shicheng Zhu Qunlei Wen Huangjingwei li Zhen li Youwen liu Yi Shen China Engineering Research Center of Nano-Geomaterials of Ministry of Education Faculty of Materials Science and ChemistryChina University of GeosciencesWuhan 430078China State Key Laboratory of Materials Processing and Die&Mould Technology and School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

Alkaline hydrogen evolution reaction(HER)offers a near-zero-emission approach to advance hydrogen ***,the activity limited by the multiple reaction steps involving H_(2)O molecules transfer,absorption,and activation still unqualified the thresholds of economic ***,we proposed a multisite complementary strategy that incorporates hydrophilic Mo and electrophilic V into Ni-based catalysts to divide the distinct steps on atomically dispersive sites and thus realize sequential regulation of the HER *** Isotopic labeled in situ Raman spectroscopy describes 4-coordinated hydrogen bonded H_(2)O to be free H_(2)O passing the inner Helmholtz plane in the vicinity of the catalysts under the action of hydrophilic Mo ***,potential-dependent electrochemical impedance spectroscopy(EIS)reveals that electrophilic V sites with abundant 3d empty orbitals could activate the lone-pair electrons in the free H_(2)O molecules to produce more protic hydrogen,and dimerize into H_(2) at the Ni *** the sequential management of reactive H_(2)O molecules,NiMoV oxides multisite catalysts surpass Pt/C hydrogen evolution activity(49 mV@10 mA∙cm^(-2) over 140 h).Profoundly,this study provides a tangible model to deepen the comprehension of the catalyst–electrolyte interface and create efficient catalysts for diverse reactions.

关键词： hydrogen evolution activity complementary multisite catalysts sequential reactive water management interfacial water molecules

Hypertriglyceridemia and acute pancreatitis:clinical and basic research—a narrative review

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Journal of Pancreatology 2024年第1期7卷 53-60页

作者： lin Gao Weiqin li Center of Severe Acute Pancreatitis(CSAP) Department of Critical Care MedicineJinling HospitalMedical School of Nanjing UniversityNanjing 210002JiangsuChina

Hypertriglyceridemia(HTG)is the third most common cause of acute pancreatitis(AP),and the incidence of HTG-induced AP(HTG-AP)is rising worldwide as a result of changes in lifestyle and dietary *** China,HTG accounts for 10%to 20%of the causes of AP,even becoming the second leading cause of *** presentation and diagnosis of HTG-AP is similar to that of AP from other causes,however,the complication rates and severe AP are significantly higher in patients with HTG-AP than in patients with other *** the management of HTG-AP,the initial management is similar to that of AP from other causes and mainly includes fluid resuscitation,pain control,and nutritional *** addition to supportive care,it is necessary to take appropriate measures to decrease serum TG levels,in order to alleviate the progression of AP and prevent *** review aims to summarize existing clinical and basic research evidence of HTG-AP and seeks to highlight the epidemiology,definition,pathogenesis,clinical course,diagnosis,management,prevention of recurrence,and specific clinical scenarios,such as HTG-AP during pregnancy,HTG-AP with diabetic ketoacidosis.

关键词： Acute pancreatitis Basic research Clinical research Hypertriglyceridemia Narrative review

Influencing factors and risk prediction model for emergence agitation after general anesthesia for primary liver cancer

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2194-2201页

作者： Shu-Shu Song li lin li li Xiao-Dong Han Department of Anesthesia and Surgery Wenzhou Central HospitalWenzhou 325099Zhejiang ProvinceChina

BACKGROUND General anesthesia is commonly used in the surgical management of gastrointestinal tumors;however,it can lead to emergence agitation(EA).EA is a common complication associated with general anesthesia,often characterized by behaviors,such as crying,struggling,and involuntary limb movements in *** treatment is delayed,there is a risk of incision cracking and bleeding,which can significantly affect surgical ***,having a proper understanding of the factors influencing the occurrence of EA and implementing early preventive measures may reduce the incidence of agitation during the recovery phase from general anesthesia,which is beneficial for improving patient *** To analyze influencing factors and develop a risk prediction model for EA occurrence following general anesthesia for primary liver *** Retrospective analysis of clinical data from 200 patients who underwent hepatoma resection under general anesthesia at Wenzhou Central Hospital(January 2020 to December 2023)was ***-surgery,the Richmond Agitation-Sedation Scale was used to evaluate EA presence,noting EA incidence after general *** were categorized by EA presence postoperatively,and the influencing factors were analyzed using logistic regression.A nomogram-based risk prediction model was constructed and evaluated for differentiation and fit using receiver operating characteristics and calibration *** EA occurred in 51(25.5%)*** analysis identified advanced age,American Society of Anesthesiologists(ASA)grade Ⅲ,indwelling catheter use,and postoperative pain as risk factors for EA(Plibration curves showed

关键词： Primary hepatocellular carcinoma resection General anesthesia Emergence agitation Risk factors Forecast Nomograph