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Journal of Arid Land 2012年第2期4卷 140-150页

作者： ZhaoFeng CHANG shujuan zhu FuGui HAN ShengNian ZHONG Minqin National Station for Desert Steppe Ecosystem Studies Minqin 733300 China Gansu Key Laboratory of Desertification Combating Lanzhou 730070 China Gansu Desert Control Research Institute Lanzhou 730070 China

Globally climates are warming. How do desert plants of different ecotypes respond to the climate change？ This paper studied the differing responses to climate warming shown by desert plants of different ecotypes through analyzing the phenology and meteorological data of 22 desert plant species growing in Minqin Desert Bo- tanical Garden in Northwest China during the period 1974-2009. The results indicate：（1） The temperature in the study area has risen quickly since 1974, and plants＇ growing periods became longer. The spring phenology of mesophytes advanced, and the autumn phenology of xerophytes was delayed; （2） The starting dates of spring phenophase of mesophytes and xerophytes differed significantly and both showed an advancing trend; （3） The spring phenology of mesophytes advanced by more days than that of xerophytes, whereas the autumn phenology of mesophytes was delayed by less days than that of the xerophytes; and （4） Mesophytes are more sensitive than xerophytes to rising temperature in spring and falling temperature in autumn. These findings are of value in plant management and regional introduction of different species.

关键词： desert plants plant phenology phenophases ecotypes climate warming Minqin

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The roles and mechanisms of SREBP1 in cancer development and drug response

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Genes & Diseases 2024年第4期11卷 258-269页

作者： Ying He Shasha Qi Lu Chen Jinyu zhu Linda Liang Xudong Chen Hao Zhang Lvjia zhuo shujuan Zhao Shuiping Liu Tian Xie School of Pharmacy Hangzhou Normal UniversityHangzhouZhejiang 311121China Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines Engineering Laboratory of Development and Application of Traditional Chinese MedicinesCollaborative Innovation Center of Traditional Chinese Medicines of Zhejiang ProvinceHangzhou Normal UniversityHangzhouZhejiang 311121China Laboratory of Cancer Genomics Division of Cellular and Molecular ResearchNational Cancer Centre SingaporeSingapore 169610Singapore

Cancer occurrence and development are closely related to increased lipid produc-tion and glucose *** are the basic component of the cell membrane and play a significant role in cancer cell processes such as cell-to-cell recognition,signal transduction,and energy supply,which are vital for cancer cell rapid proliferation,invasion,and *** regulatory element-binding transcription factor 1(SREBP1)is a key transcription factor regulating the expression of genes related to cholesterol biosynthesis,lipid homeostasis,and fatty acid *** addition,SREBP1 and its upstream or downstream target genes are implicated in various metabolic diseases,particularly ***,no review of sREBP1 in cancer biology has yet been ***,we summarized the roles and mechanisms of SREBP1 biological processes in cancer cells,including SREBP1 modification,lipid metabolism and reprogramming,glucose and mitochondrial metabolism,immunity,and tumor microenvi-ronment,epithelial-mesenchymal transition,cell cycle,apoptosis,and ***-ally,we discussed the potential role of SREBP1 in cancer prognosis,drug response such as drug sensitivity to chemotherapy and radiotherapy,and the potential drugs targeting SREBP1 and its corresponding pathway,elucidating the potential clinical application based on SREBP1 and its corresponding signal pathway.

关键词： Cancer Drug Lipid metabolism reprogramming Resistance SREBP1

广义二维多项式混沌映射及其在信息传输中的应用

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通信学报 2022年第9期43卷 80-89页

作者：闫文浩姜子敬黄欣朱淑娟丁群黑龙江大学电子工程学院黑龙江哈尔滨150080 澳大利亚佛林德斯大学科学与工程学院通斯利SA 5042

现有混沌映射在工程应用中存在许多缺陷,如混沌参数范围不连续、弱混沌、混沌序列输出不均匀和动力学退化等。基于此,提出了一种广义二维多项式混沌映射,通过设定不同控制参数和多项式最高次数,得到一系列特定Lyapunov指数的二维多项式... 详细信息

现有混沌映射在工程应用中存在许多缺陷,如混沌参数范围不连续、弱混沌、混沌序列输出不均匀和动力学退化等。基于此,提出了一种广义二维多项式混沌映射,通过设定不同控制参数和多项式最高次数,得到一系列特定Lyapunov指数的二维多项式混沌映射。为避免该映射第二个状态方程的输出塌陷为一个固定值,引入了一个不随时间变化的随机扰动变量。然后,通过具体的数值实例验证了该映射的有效性,动力分析表明该映射具有复杂的动力学行为。最后,将该映射应用于信息传输技术,相较于其他混沌映射,该映射可以取得更小的误码率,表明该混沌映射更适用于混沌信息传输。

关键词： Lyapunov指数动力学退化混沌映射信息传输

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Effect of the electro-acupuncture on senile plaques and its formation in APPD/PS1D double transgenic mice

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Genes & Diseases 2019年第3期6卷 282-289页

作者： Qinghua Yang shujuan zhu Jin Xu Chenglin Tang Kaihui Wu Yanjun Wu Yiying Wang Huajun Sheng Institute of Neuroscience Chongqing Medical UniversityChongqingChina College of Traditional Chinese Medicine Chongqing Medical UniversityChongqingChina

Alzheimer’s disease(AD)is a progressive neurodegenerative disease and its incidence will increase with age and is *** senile plaques(SPs)are one of three main pathological features in AD patients,which are formed by amyloid b-protein(Ab)overaccumulation.b-amyloid precursor protein(APP),b-site APP cleavage(BACE1),and insulin degrading enzyme(IDE)proteins participate in the process of Ab production and *** present,the pathogenesis of AD is not yet clear and the current treatment methods can only relief the related symptoms of *** electro-acupuncture(EA)is a traditional Chinese medicine treatment combined the acupuncture and electrical stimulation and the treatment effect can also be controlled by transform the electrical ***,in this experiment,we carried out behavioral test,immunohistochemistry(IHC),and Western Blot(WB)after different period treatments to the model mice by electro-acupuncturing“Baihui”and“Shenshu”acupoints in APPt/PS1t double transgenic *** was found that the EA therapy can improve the ability of learning,memory and spatial exploration,and reduce the deposition of SPs in brain of AD model mice,and reduce the expressions of APP and BACE1,increase the expression of IDE *** results prompt that EA can effectively alleviate the pathological process of *** speculate that EA may play a comprehensive role in preventing the development of AD,considering the previous data.

关键词： Alzheimer’s disease Amyloid b-protein Electro-acupuncture Senile plaques Transgenic mice

Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat

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Science China Life Sciences 2024年

作者： Xuemei Liu Min Deng Bingxin Shi Kehui zhu Jinchao Chen shujuan Xu Xiaomin Bie Xiansheng Zhang Xuelei Lin Jun Xiao Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology Chinese Academy of Sciences University of Chinese Academy of Sciences Institute of Science and Technology Austria (ISTA) National Key Laboratory of Wheat Improvement College of Life Sciences Shandong Agricultural University Centre of Excellence for Plant and Microbial Science (CEPAMS) JIC-CAS

Winter plants rely on vernalization, a crucial process for adapting to cold conditions and ensuring successful reproduction. However,understanding the role of histone modifications in guiding the vernalization process in winter wheat remains limited. In this study, we investigated the transcriptome and chromatin dynamics in the shoot apex throughout the life cycle of winter wheat in the field. Two core histone modifications, H3K27me3 and H3K36me3, exhibited opposite patterns on the key vernalization gene VERNALIZATION1(VRN1),correlating with its induction during cold exposure. Moreover, the H3K36me3 level remained high at VRN1 after cold exposure, which may maintain its active state. Mutations in FERTILIZATION-INDEPENDENT ENDOSPERM(TaFIE) and SET DOMAIN GROUP 8/EARLY FLOWERING IN SHORT DAYS(TaSDG8/TaEFS), components of the writer complex for H3K27me3 and H3K36me3, respectively, affected flowering time. Intriguingly, VRN1 lost its high expression after the cold exposure memory in the absence of H3K36me3. During embryo development,VRN1 was silenced with the removal of active histone modifications in both winter and spring wheat, with selective restoration of H3K27me3 in winter wheat. The mutant of Tafie-cr-87, a component of H3K27me3 “writer” complex, did not influence the silence of VRN1during embryo development, but rather attenuated the cold exposure requirement of winter wheat. Integrating gene expression with H3K27me3 and H3K36me3 patterns identified potential regulators of flowering. This study unveils distinct roles of H3K27me3 and H3K36me3 in controlling vernalization response, maintenance, and resetting in winter wheat.

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The formation age and evolution of Kumtagh Desert

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Journal of Arid Land 2011年第2期3卷 114-122页

作者： JinNian TANG Zhizhu SU Feng DING shujuan zhu YouHao E XinWei ZHAI ZhiYu Yl HuJun LIU JinChun ZHANGI FaMing LI Minqin National Studies Station for Desert Steppe Ecosystem Minqin 733300 China State key Laboratory Breeding Base of Desertification and Aeolian Sand Disaster Combating Gansu Desert Control ResearchInstitute Lanzhou 730070 China School of History and Culture Shanxi University Taiyuan 030006 China Lanzhou University Lanzhou 730000 China

The ancient aeolian sand has been regarded as an indicator for the formation and evolution of a desert in the *** Desert is located at the northern fringe of Qinghai-Tibet *** first integrated scientific investigation to the desert was carried out during the period of *** Desert is an ideal natural model for studying the formation and evolution of the desert because the Quaternary strata containing ancient aeolian sands are widely *** integrated field investigation and studies on sedimentary,chronology and palynology of typical profiles named Suosuo gully,Xiaoquan gully and gravel body with ancient aeolian sand layers showed that Kumtagh Desert was probably formed as early as 2,097.7±314.7 ka *** the period of 386.9±58.0 ka BP to 285.9±42.9 ka BP,the desert largely expanded and formed its modern distribution *** desert was originally developed in the southwest,subsequently,expanded to the north and *** sedimentary facies of Suosuo gully profile revealed that the desert experienced at least 19 cycles of advance and inverse processes of desertification with an average period of 110 ka in the *** neotectonic movements played an important role in the formation,development and geomorphology of the *** one hand,the movements caused the formation of intermontane fault basin,which was further developed towards the closed drought basin,and caused the formation of natural *** the other hand,under the control of surrounding faults,the unique broom-shaped desert landscape was formed,and the gullies and sand ridges in this region experienced an abrupt directional change from north by west to north by east at the location of 39°45＇-39°55＇*** unique landscape of gravel body that occurred widely in the northern desert was formed after 285.9±42.9 ka *** results in this paper provide the scientific basis for studying the formation age and evolutionary process under the dry climate and

关键词： Kumtagh Desert formation age evolution ancient aeolian sand

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Regulation of"P35/P25-CDK5-Tau"signaling pathway in hippocampi and prefrontal cortex of AD rats by electroacupuncture

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解剖学杂志 2021年第S1期44卷 127-128页

作者： zhu shujuan Sheng Huajun Xu Jin Department of Human Anatomy Chongqing Medical UniversityChongqing 400016China

Fifty SD rats were randomly divided into control,sham,model and electroacupuncture treatment group in this *** model rats were established by injecting *** into the hippocampi,while the same amount of saline was injected into the sham *** model rats were treated by electroacupuncture stimulation at"Baihui"and"Shenshu"acupoints once a day for 10 *** behavioral experiments results showed that the learning and memory ability of the AD rats were significantly decreased compared with the controls and shams,while depression-related behaviors were significantly increased.

关键词： electroacupuncture rats stimulation

Psychometric properties of the Chinese version of the Infertility Self-Efficacy Scale

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International Journal of Nursing Sciences 2016年第3期3卷 259-267页

作者： Bing Fu Pingping Yan Hang Yin shujuan zhu Qing Liu Yulan Liu Chanyuan Dai Guanxiu Tang Chunli Yan Jun Lei The Third Xiangya Hospital of Central South University PR China Xiang Ya Nursing School of Central South University PR China

Objective:To translate the English version of Infertility Self-Efficacy Scale into Chinese and to validate the psychometric properties of the Chinese version of the Infertility Self-Efficacy Scale(CISE).Method(s):Participants were recruited from the Gynecology Department of two city *** main processes were involved in the formation of CISE[1]:scale translation based on expert consultation[2];pre-test questionnaire development with infertile women's feedback(N=20)[3];factor structure assessed by exploratory and confirmatory factor analysis(N=177)[4];assessment of reliability by internal consistency(N=177)and test-retest reliability(N=21);and[5]assessment of convergent validity with Self-rating Anxiety Scale,Self-rating Depression Scale,and Simplified Coping Style Questionnaire(N=177).Results:This study established a 16-item *** analyses confirmed a onecomponent solution,which explained 54.59% of total variances and showed an acceptable model ***'s a and test-retest correlation coefficients for the scale were 0.94 and 0.84,*** CISE score was significantly correlated with anxiety(r=0.47),depression(r=0.60),positive coping style(r=0.37),and certain negative coping style ***:This 16-item CISE is a reliable and valid measure to evaluate perceived selfefficacy among a sample of Chinese women who underwent infertility treatment.

关键词： Confirmatory factor analysis Infertility Scale Self-efficacy Women

Regulation of "P35/P25-CDK5-Tau" signaling pathway in hippocampi and prefrontal cortex of AD rats by electroacupuncture

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Regulation of "P35/P25-CDK5-Tau" signaling pathway in hippoc...

Expert consensus on pediatric orthodontic therapies of malocclusions in children

中国解剖学会2021年年会

作者： zhu shujuan Sheng Huajun Xu Jin Department of Human Anatomy Chongqing Medical University

Fifty SD rats were randomly divided into control,sham,model and electroacupuncture treatment group in this *** model rats were established by injecting Aβ into the hippocampi,while the same amount of saline was injected into the sham *** model rats were treated by electroacupuncture stimulation at "Baihui" and "Shenshu" acupoints once a day for 10 days.

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International Journal of Oral Science 2024年第2期16卷 186-196页

作者： Chenchen Zhou Peipei Duan Hong He Jinlin Song Min Hu Yuehua Liu Yan Liu Jie Guo Fang Jin Yang Cao Lingyong Jiang Qingsong Ye Min zhu Beizhan Jiang Wenhua Ruan Xiao Yuan Huang Li Rui Zou Yulou Tian Li Gao Rui Shu Jianwei Chen Renkai Liu shujuan Zou Xiaobing Li State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Pediatric Dentistry West China Hospital of StomatologySichuan UniversityChengduChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Orthodontics West China Hospital of StomatologySichuan UniversityChengduChina State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration&Key Laboratory of Oral Biomedicine Ministry of Education&Hubei Key Laboratory of Stomatology&Department of Orthodontics&Center for Dentofacial Development and Sleep Medicine School and Hospital of StomatologyWuhan UniversityWuhanChina Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences&Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education Stomatological Hospital of Chongqing Medical UniversityChongqing Medical University&College of StomatologyChongqing Medical UniversityChongqingChina Department of Orthodontics Hospital of StomatologyJilin UniversityChangchunChina Department of Orthodontic&Oral Biomedical Engineering Laboratory Shanghai Stomatological HospitalFudan UniversityShanghaiChina Department of Orthodontics Central LaboratoryPeking University School and Hospital for Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical Devices&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental Materials&National Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijingChina Department of Orthodontics School and Hospital of StomatologyCollege of MedicineShandong University&Shandong Key Laboratory of Oral Tissue Regeneration&Shandong Engineering Laboratory for Dental Materials and Oral Tissue

Malocclusion,identified by the World Health Organization(WHO)as one of three major oral diseases,profoundly impacts the dental-maxillofacial functions,facial esthetics,and long-term development of~260 million children in *** its physical manifestations,malocclusion also significantly influences the psycho-social well-being of these *** intervention in malocclusion can foster an environment conducive to dental-maxillofacial development and substantially decrease the incidence of malocclusion or reduce the severity and complexity of malocclusion in the permanent dentition,by mitigating the negative impact of abnormal environmental influences on the *** orthodontic treatment encompasses accurate identification and treatment of dental and maxillofacial morphological and functional abnormalities during various stages of dental-maxillofacial development,ranging from fetal stages to the early permanent dentition *** an economic and societal standpoint,the urgency for effective early orthodontic treatments for malocclusions in childhood cannot be overstated,underlining its profound practical and social *** consensus paper discusses the characteristics and the detrimental effects of malocclusion in children,emphasizing critical need for early *** elaborates on corresponding core principles and fundamental approaches in early orthodontics,proposing comprehensive guidance for preventive and interceptive orthodontic treatment,serving as a reference for clinicians engaged in early orthodontic treatment.

关键词： permanent stated children