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Stratigraphic Sequence and Sedimentary Systems in the Middle-Southern Continental Slope of the East China Sea from Seismic Reflection Data: Exploration Prospects of Gas Hydrate

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Journal of Ocean University of China 2019年第6期18卷 1302-1316页

作者： LI Deyong CHEN Hongyan xu shujuan XING Junhui CHENG Honggang WANG Jinkai Key Laboratory of Submarine Geosciences and Prospecting Techniques MOECollege of Marine GeosciencesOcean University of ChinaQingdao 266100China Shandong Provincial Key Laboratory of Depositional Mineralization&Sedimentary Minerals Shandong University of Science and TechnologyQingdao 266590China Evaluation and Detection Technology Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266100China Research Institute of Petroleum Exploration&Development Langfang 065007China College of Earth Science and Engineering Shandong University of Science and TechnologyQingdao 266590China

Many evidences for gas hydrate bearing sediments had been found in the continental slope of the East China Sea,such as bottom simulating reflections(BSRs),undersea gas springs,pyrite associated with methane leakage,mud diapirs/mud volcanos,bottom-water methane anomalies and so *** this study,six key stratigraphic interfaces including T_0(seafloor),T_1(LGM,23 kyr B.P.),T_2(2.58 Myr),T_3(5.33 Myr),T_4(11.02 Myr)and T_5(16.12 Myr)were identified,and then five third-order sequences of SQIII1 to SQIII5 were ***,T5 in southern continental slope is not found,which shows that the middle-northern Okinawa Trough had begun to rift in the early Miocene,earlier than the southern *** system tracts including lowstand systems tract(LST),transgressive systems tract(TST),highstand systems tract(HST)and falling stage systems tract(FSST)are further *** marine erosion interface of 11.02 Myr and regressive unconformity interface of 23 kyr *** two large-scale sea level drop events in the research *** typical seismic facies identified in the continental slope are continental shelf-edge deltas,littoral fluvial-delta plains,incised channels or submarine canyons,slope fans,submarine fans or coastal sandbars,littoral-neritic finegrained sediments,mud volcanos and some other geological bodies *** minimum water depth for hydrate occurrence in the Okinawa Trough is 630 m,and the thickness of gas hydrate stability zone in continental slope is between 0 and 590 *** calculated bottom boundary of hydrate stability zone is slightly deeper than BSRs on the seismic *** re-depositional turbidite sand bodies,such as canyon channels,slope fans and submarine fans developed in Quaternary strata,are the predominant hydrate *** to developing process,the dynamic accumulation of hydrate systems can be divided into three evolutionary stages including canyon erosion and hydrate stability zone migration stage,sediments destabili

关键词： sequence stratigraphic architecture systems tract seismic facies depositional system submarine canyon gas hydrate stability zone hydrate dynamic accumulation continental slope of the East China Sea

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The vernalization-induced long non-coding RNA VAS functions with the transcription factor TaRF2b to promote TaVRN1 expression for flowering in hexaploid wheat

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Molecular Plant 2021年第9期14卷 1525-1538页

作者： shujuan xu Qi Dong Min Deng Dexing Lin Jun Xiao Peilei Cheng Lijing Xing Yuda Niu Caixia Gao Wenhao Zhang Yunyuan xu Kang Chong Key Laboratory of Plant Molecular Physiology Institute of BotanyChinese Academy of SciencesBeijing 100093China University of Chinese Academy of Sciences Beijing 100049China Innovation Academy for Seed Design Chinese Academy of SciencesBeijing 100093China State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China State Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental BiologyInnovation Academy for Seed DesignChinese Academy of SciencesBeijing 100101China State Key Laboratory of Plant Cell and Chromosome Engineering Center for Genome EditingInstitute of Genetics and Developmental BiologyInnovation Academy for Seed DesignChinese Academy of SciencesBeijing 100101China College of Horticulture Nanjing Agricultural UniversityKey Laboratory of LandscapingMinistry of AgricultureNanjing 210095China CAS-JIC Centre of Excellence for Plant and Microbial Science Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China

Vernalization is a physiological process in which prolonged cold exposure establishes flowering competence in winter plants. In hexaploid wheat, TaVRN1 is a cold-induced key regulator that accelerates floral transition. However, the molecular mechanism underlying the gradual activation of TaVRN1 during the vernalization process remains unknown. In this study, we identified the novel transcript VAS (TaVRN1 alternative splicing) as a non-coding RNA derived from the sense strand of the TaVRN1 gene only in winter wheat, which regulates TaVRN1 transcription for flowering. VAS was induced during the early period of vernalization, and its overexpression promoted TaVRN1 expression to accelerate flowering in winter wheat. VAS physically associates with TaRF2b and facilitates docking of the TaRF2b-TaRF2a complex at the TaVRN1 promoter during the middle period of vernalization. TaRF2b recognizes the Sp1 motif within the TaVRN1 proximal promoter region, which is gradually exposed along with the disruption of a loop structure at the TaVRN1 locus during vernalization, to activate the transcription of TaVRN1. The tarf2b mutants exhibited delayed flowering, whereas transgenic wheat lines overexpressing TaRF2b showed earlier flowering. Taken together, our data reveal a distinct regulatory mechanism by which a long non-coding RNA facilitates the transcription factor targeting to regulate wheat flowering, providing novel insights into the vernalization process and a potential target for wheat genetic improvement.

关键词： winter wheat vernalization flowering long non-coding RNA chromosome loop

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Distinct roles of H3K27me3 and H3K36me3 in vernalization response,maintenance,and resetting in winter wheat

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Science China(Life Sciences) 2024年第10期67卷 2251-2266页

作者： xuemei Liu Min Deng Bingxin Shi Kehui Zhu Jinchao Chen shujuan xu Xiaomin Bie Xiansheng Zhang xuelei Lin Jun Xiao Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Institute of Science and Technology Austria(ISTA) Klosterneuburg 3400Austria National Key Laboratory of Wheat Improvement College of Life SciencesShandong Agricultural UniversityTai’an 271018China Centre of Excellence for Plant and Microbial Science(CEPAMS) JIC-CASBeijing 100101China

Winter plants rely on vernalization,a crucial process for adapting to cold conditions and ensuring successful ***,understanding the role of histone modifications in guiding the vernalization process in winter wheat remains *** this study,we investigated the transcriptome and chromatin dynamics in the shoot apex throughout the life cycle of winter wheat in the *** core histone modifications,H3K27me3 and H3K36me3,exhibited opposite patterns on the key vernalization gene VERNALIZATION1(VRN1),correlating with its induction during cold ***,the H3K36me3 level remained high at VRN1 after cold exposure,which may maintain its active *** in FERTILIZATION-INDEPENDENT ENDOSPERM(TaFIE)and SET DOMAIN GROUP 8/EARLY FLOWERING IN SHORT DAYS(TaSDG8/TaEFS),components of the writer complex for H3K27me3 and H3K36me3,respectively,affected flowering ***,VRN1 lost its high expression after the cold exposure memory in the absence of *** embryo development,VRN1 was silenced with the removal of active histone modifications in both winter and spring wheat,with selective restoration of H3K27me3 in winter *** mutant of Tafie-cr-87,a component of H3K27me3“writer”complex,did not influence the silence of VRN1during embryo development,but rather attenuated the cold exposure requirement of winter *** gene expression with H3K27me3 and H3K36me3 patterns identified potential regulators of *** study unveils distinct roles of H3K27me3 and H3K36me3 in controlling vernalization response,maintenance,and resetting in winter wheat.

关键词： vernalization H3K27me3 H3K36me3 winter wheat resetting maintenance

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Engineering G-quadruplex aptamer to modulate its binding specificity

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National Science Review 2021年第4期8卷 107-113页

作者： Long Li shujuan xu xueyu Peng Yuzhuo Ji He Yan Cheng Cui Xiaowei Li Xiaoshu Pan Lu Yang Liping Qiu Jianhui Jiang Weihong Tan Department of Chemistry and Department of Physiology and Functional Genomics Center for Research at the Bio/Nano Interface Health Cancer Center UF Genetics InstituteMcKnight Brain Institute University of Florida Molecular Science and Biomedicine Laboratory State Key Laboratory of Chemo/Biosensing and ChemometricsCollege of Chemistry and Chemical Engineering College of Biology Aptamer Engineering Center of Hunan ProvinceHunan University Molecular Science and Biomedicine Laboratory(MBL) State Key Laboratory of Chemo/Biosensing and ChemometricsCollege of Chemistry and Chemical Engineering College of Biology Aptamer Engineering Center of Hunan ProvinceHunan University Institute of Molecular Medicine(IMM) Renji HospitalShanghai Jiao Tong University School of Medicine and College of Chemistry and Chemical EngineeringShanghai Jiao Tong University

The use of aptamers in bioanalytical and biomedical applications exploits their ability to recognize cell surface protein receptors. Targeted therapeutics and theranostics come to mind in this regard. However,protein receptors occur on both cancer and normal cells; as such, aptamers are now taxed with identifying high vs. low levels of protein expression. Inspired by the flexible template mechanism and elegant control of natural nucleic acid-based structures, we report an allosteric regulation strategy for constructing a structure-switching aptamer for enhanced target cell recognition by engineering aptamers with DNA intercalated motifs(i-motifs) responsive to the microenvironment, such as p H. Structure-switching sensitivity can be readily tuned by manipulating i-motif sequences. However, structure-switching sensitivity is difficult to estimate, making it equally difficult to effectively screen modified aptamers with the desired sensitivity. To address this problem, we selected a fluorescent probe capable of detecting G-quadruplex in complicated biological media.

关键词： G-quadruplex aptamer i-motif binding specificity cell microenvironment

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Probing photocarrier dynamics of pressurized graphene using time-resolved terahertz spectroscopy

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Chinese Physics B 2023年第6期32卷 614-620页

作者：王云峰许淑娟杨金苏付海 Key Laboratory of Materials Physics Institute of Solid State PhysicsHFIPSChinese Academy of SciencesHefei 230031China University of Science and Technology of China(USTC) Hefei 230026China

Graphene hosts intriguing photocarrier dynamics such as negative transient terahertz(THz) photoconductivity, high electron temperature, benefiting from the unique linear Dirac dispersion. In this work, the pressure effects of photocarrier dynamics of graphene have been investigated using in situ time-resolved THz spectroscopy in combination with diamond anvil cell exceeding 9 GPa. We find that the negative THz conductivity maintains in our studied pressure range both for monolayer and bilayer graphene. In particular, the amplitude of THz photoconductivity in monolayer graphene manifests an extraordinary dropping with pressure, compared with that from the counterparts such as bulk silicon and bilayer ***, the time constant is reduced with increasing pressure, highlighting the pressure-induced hot carrier *** pressure dependence of photocarrier dynamics in monolayer graphene is likely related with the enhancement of the interfacial coupling between diamond surface and sample, allowing for the activity of new electron–phonon scattering. Our work is expected to provide an impetus for the studies of high-pressure THz spectroscopy of two-dimensional materials.

关键词： terahertz photocarrier dynamics graphene high pressure

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DDX56 antoginizes IFN-β production to enhance EMCV replication by inhibiting IRF3 nuclear translocation

DDX56 antoginizes IFN-β production to enhance EMCV replicat...

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第十四届全国免疫学学术大会

作者： Jingying Xie shujuan xu Ruofei Feng Biomedical Research Center Northwest Minzu University

DEAD(Glu-Asp-Ala-Glu)-box RNA helicases(DDX) play important roles in viral infection,either as cytosolic viral nucleic acids sensors or as essential host factors for viral *** this study,we identified DDX56 as a positive regulator for encephalomyocarditis virus(EMCV) *** infection promotes DDX56 expression via its viral proteins,VP3 and 3 *** showed that DDX56 overexpression promotes EMCV replication whereas its loss dampened EMCV ***,knockdown of DDX56 increases type Ⅰ interferon(IFN) expression during EMCV *** also showed that DDX56 interrupts IFN regulatory factor 3(IRF3) phosphorylation and its nucleus translocation by directly targeting KPNA3 and KPNA4 in an EMCV-triggered MDA5 signaling activation cascade leading to the blockade of IFN-β***,we showed that DDX56 is a novel negative regulator of EMCV-mediated IFN-β responses and that DDX56 plays a critical role in EMCV *** findings reveal a novel strategy for EMCV to utilize a host factor to evade the host innate immune response and provide us new insight into the function of DDX56.

关键词： DDX56 EMCV IRF3 IFN-β signaling pathway

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期待视野下大学生就业路径优化研究

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江苏高教 2023年第2期 97-101页

作者：徐淑娟金陵科技学院园艺园林学院南京211169

在后疫情时代,引入期待视野理论对于优化大学生就业问题研究具有现实意义。深入研究大学生的接受心理,是实现高校就业工作的基础;充分发挥大学生的主体性,是解决大学生就业问题的根本。大学生就业指导工作是高校、教师、社会共同协作的... 详细信息

在后疫情时代,引入期待视野理论对于优化大学生就业问题研究具有现实意义。深入研究大学生的接受心理,是实现高校就业工作的基础;充分发挥大学生的主体性,是解决大学生就业问题的根本。大学生就业指导工作是高校、教师、社会共同协作的过程。但目前传统的就业指导工作模式亟待打破,整齐划一的目标要求、简单的课程安排、相对集中的实践教育已无法满足当前的就业市场需求。建立一个以大学生为中心,政府、社会、高校、家庭为联合体的就业互动机制是优化大学生就业的可行之策。

关键词：期待视野接受心理大学生就业

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“先驱”转录因子LEC1在早期胚胎重置春化状态的机制

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植物学报 2018年第1期53卷 1-4页

作者：许淑娟种康中国科学院植物研究所植物分子生理学重点实验室北京100093 中国科学院大学北京100049

开花是植物由营养生长阶段向生殖生长阶段转变的重要过程,长时间低温处理即春化对开花起到非常重要的促进作用。春化控制的拟南芥(Arabidopsis thaliana)开花中,阻抑型转录因子FLC是重要的关节点,春化记忆依赖于对该基因的控制。何跃辉... 详细信息

开花是植物由营养生长阶段向生殖生长阶段转变的重要过程,长时间低温处理即春化对开花起到非常重要的促进作用。春化控制的拟南芥(Arabidopsis thaliana)开花中,阻抑型转录因子FLC是重要的关节点,春化记忆依赖于对该基因的控制。何跃辉研究组之前对拟南芥的研究揭示了转录因子VAL1或VAL2可以识别负调控开花的关键基因FLC成核区的顺式DNA元件,协同PRC2复合体在春化过程中沉默FLC基因的表达,并在随后的常温下继续维持FLC基因沉默直至受精结束,使植物产生春化记忆。但在下一代中如何擦除这种记忆功能,使FLC重新被激活,以防止植物在过冬前或过冬时开花,相关机制目前并不清楚。近期,该研究组揭示了在植物胚胎发育早期一个种子特有的"先驱"转录因子参与擦除春化记忆,重新激活FLC基因的分子机制,并解析了胚胎中的基因激活传递到后胚胎发育(营养生长期)的表观遗传机理。该研究是开花领域的重要突破,为作物开花调控的生产应用提供了新思路。

关键词：染色体重塑表观调控春化作用春化记忆

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农村金融市场发育对种粮大户形成的影响——文献回顾与理论梳理

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中国农业大学学报 2019年第10期24卷 230-238页

作者：蔡键许淑娟米运生华南农业大学经济管理学院广州510642 华南农业大学国家农业制度与发展研究院广州510642

为厘清中国农村金融市场的发育现状,探究农村信贷市场和农业保险市场发育对种粮大户形成的影响机理,采用文献综述的研究方法,对相关研究进行系统性回顾和理论梳理。结果表明:第一,适度扩大粮农经营规模对于中国农业发展具有重要的现实意... 详细信息

为厘清中国农村金融市场的发育现状,探究农村信贷市场和农业保险市场发育对种粮大户形成的影响机理,采用文献综述的研究方法,对相关研究进行系统性回顾和理论梳理。结果表明:第一,适度扩大粮农经营规模对于中国农业发展具有重要的现实意义;第二,农村金融市场发育完善与否是能否扩大粮农经营规模的关键;第三,现阶段中国的农村金融市场发育不完善,不利于农户获得信贷与保险。综述可证:信贷市场发育不完善将阻碍粮农获得资本,不利于要素替代进而扩大生产规模;保险市场发育不完善将阻碍粮农获得保险,不利于规模扩大后的粮农稳定生产。

关键词：信贷保险种粮大户文献综述

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花洒塑料喷头圆弧抽芯注射模设计

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工程塑料应用 2012年第1期40卷 55-58页

作者：张维合许淑娟广东科技学院广东东莞523083 东莞理工学院广东东莞523083

介绍了一款三功能手握花洒塑料喷头注射模设计,该模具采用外螺纹侧向抽芯以及圆弧侧向抽芯机构,圆弧抽芯的动力来源于马达。模具多处采用喷管件冷却,成型的塑料件最后由推管推出。模具结构复杂新颖,动作稳定可靠。

关键词：手握花洒塑料喷头辅助流道马达圆弧抽芯喷管件推管脱模定距分型机构

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