检索结果-南通市图书馆

维普期刊数据库

Frequency dependence of electron temperature in hollow cathode-type discharge as measured by several different floating probe methods

在线全文

学校读者我要写书评

暂无评论

Plasma Science and Technology 2018年第8期20卷 50-57页

作者： shuichi sato Hiromu KAWANA Tatsushi FUJIMINE Mikio OHUCHI Department of Electronic Engineering Tokyo Denki University

We measured electron temperatures through a hollow cathode-type discharge tube using several different floating probe methods. This method detected a shift in the floating potential when an AC voltage was applied to a probe through an intermediary blocking capacitor. The shift in the floating potential is described as a function of the electron temperature and the applied AC voltage. In this study, the effects of the frequency and waveform on the electron temperatures were systematically investigated. The electron temperature measured when using the floating probe method with applied sinusoidal and triangular voltages was lower than that measured with an applied rectangular voltage.The value in the high frequency range was close to that of the tail electron temperature.

关键词： electrostatic probe Langmuir probe floating potential electron temperature sheath

维普期刊数据库

A dose-up of ursodeoxycholic acid decreases transaminases in hepatitis C patients

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第22期15卷 2782-2786页

作者： shuichi sato Tatsuya Miyake Hiroshi Tobita Naoki Oshima Junichi Ishine Takuya Hanaoka Yuji Amano Yoshikazu Kinoshita Department of Gastroenterology and Hepatology Shimane UniversitySchool of Medicine Division of Gastrointestinal Endoscopy Shimane University Hospital

AIM:To examine whether a dose-up to 900 mg of ursodeoxycholic acid(UDCA) decreases transaminases in hepatitis C patients.METHODS:From January to December 2007,patients with chronic hepatitis C or compensated liver cirrhosis with hepatitis C virus(HCV)(43-80 years old) showing positive serum HCV-RNA who had already taken 600 mg/d of UDCA were recruited into this study.Blood parameters were examined at 4,8 and 24 wk after increasing the dose of oral UDCA from 600 to 900 mg/d.RESULTS:Serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),and gamma-glutamyl transpeptidase(GGT) levels were signifi cantly decreased following the administration of 900 mg/d as compared to 600 mg/d.The decrease in ALT from immediately before the dose-up of UDCA to 8 wk after the dose-up was 14.3 IU/L,while that for AST was 10.5 IU/L and for GGT was 9.8 IU/L.Platelet count tended to increase after the dose-up of UDCA,although it did not show a statistically signifi cant level(P=0.05).Minor adverse events were observed in 3 cases,although no drop-outs from the study occurred.CONCLUSION:Oral administration of 900 mg/d of UDCA was more effective than 600 mg/d for reducing ALT,AST,and GGT levels in patients with HCV-related chronic liver disease.

关键词：丙氨酸转氨酶丙型肝炎病毒熊去氧胆酸加剂量患者阳性血清国际单位谷草转氨酶

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

MAOS器件电荷存贮特性的研究

计算机工程与应用 1975年第8期 27-35页

作者： shuichi sato TADANORI YAMAGUCHI ,蔡庚富

金属-Al2O3-SiO2-硅（MAOS）场效应晶体管的基本特性和电荷存贮特性作为氧化物厚度的函数已进行了研究。测量了SiO2膜为50A°和Al2O3为700A°的器件的典型电荷存贮特性。依据隧道效应机理电子和空穴穿过薄的SiO2层的传输过程和从Al电极... 详细信息

金属-Al2O3-SiO2-硅（MAOS）场效应晶体管的基本特性和电荷存贮特性作为氧化物厚度的函数已进行了研究。测量了SiO2膜为50A°和Al2O3为700A°的器件的典型电荷存贮特性。依据隧道效应机理电子和空穴穿过薄的SiO2层的传输过程和从Al电极的电子注入对结果进行了解释。在MAOS结构中,阈值电压从初始状态漂移在大约23伏以内。而且可以在适当应力条件下改变电场反转控制。至少10～6次以上。可以认为电荷存贮时间在室温下实际上是无限长的,在150℃是10～6小时数量级。在反复循环施加电场应力下器件参数的故障行为也可依据在Al2O3膜内和在Al2O3和SiO2膜界面的电子积累予以考虑。

关键词：氧化铝膜晶体管半导体三极管 MAOS 器件二氧化硅膜隧道效应电荷金属电极电磁场电场滞后特性电压脉冲

Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2022年第5期15卷 4201-4211页

作者： Tsukasa Akasaka Miho Tamai Yoshitaka Yoshimura Natsumi Ushijima Shinichiro Numamoto Atsuro Yokoyama Hirofumi Miyaji Ryo Takata shuichi Yamagata Yoshiaki sato Ko Nakanishi Yasuhiro Yoshida Department of Biomaterials and Bioengineering Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Immune Signal Unit Okinawa Institute of Science and Technology Graduate UniversityOkinawa 904-0495Japan Department of Pharmacology Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Support Section for Education and Research Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Oral Functional Prosthodontics Division of Oral Functional ScienceFaculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Periodontology and Endodontology Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Orthodontics Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan

The surface topography of a material can influence osteoclast activity.However,the surface structural factors that promote osteoclast activity have not yet been investigated in detail.Therefore,we investigated osteoclastogenesis by testing various defined patterns with different dimensions and shapes.The systematic patterns,made of a cyclo-olefin polymer,were prepared at a micron-,submicron-,and nano-scale with a groove,hole,or pillar shape with a 1:1 pitch ratio.RAW264.7 cells were cultured on these patterns in the presence of the receptor activator of NF-κB ligand(RANKL).Osteoclast formation was induced in the order:pillar>groove≥hole.The two-dimensional factors also indicated that submicron-sized patterns strongly induced osteoclast formation.The optimal pillar dimension for osteoclast formation was 500 nm in diameter and 2μm in height.Furthermore,we observed two types of characteristic actin structure,i.e.,belt-like structures with small hollow circles and isolated ring-like structures,which formed on or around the pillars depending on size and height.Furthermore,resorption pits were observed mainly on the top of calcium phosphate-coated pillars.Thus,osteoclasts prefer convex shapes,such as pillars for differentiation and resorption.Our results indicate that osteoclastogenesis can be controlled by designing surfaces with specific morphologies.

关键词： micro/nano-pattern pillar RAW264.7 osteoclast actin structure resorption pit

Germination and appressorium formation of Pyricularia oryzae Cavara can be inhibited by reduced concentration of Blasin~? Flowable with carbon dioxide microbubbles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2018年第9期17卷 2024-2030页

作者： Tamaki Masahiko Kobayashi Fumiyuki Suehiro Keisuke Ohsato shuichi sato Michio School of Agriculture Meiji University Faculty of Applied Life Science Nippon Veterinary and Life Science University

We investigated the possibility to reduce the usage of Blasin^Flowable （BF）, a disinfectant inhibiting the germination and appressorium formation of Pyricularia oryzae Cavara conidia, by using carbon dioxide microbubbles （CO2MB）. Germination was significantly inhibited by 10 000-fold diluted BF solution containing CO2MB generated by the decompression-type generator compared to CO2 millibubbles （CO2MMB） and CO2MB generated by the gas-water circulating-type generator. Appressodum formation in the 10 000-fold diluted BF solution containing both CO2MBs was less than that in CO2MMB. Scanning electron microscopy showed wrinkles and dents on the surface of conidia treated with 5 000-fold diluted BF solution containing both CO2MBs. Via transmission electron microscopy, we observed the expansion of the vacuole and the intracellular space and bloated or absent lipid granules in the conidia treated with BF solution containing both CO2MBs. Our results show that inhibition of the conidium germination and appressorium formation of P. oryzae Cavara by 10 000-fold diluted BF solution could be achieved by using the decompression-type CO2MB.

关键词： appressorium formation Blasin^Flowable germination Pyricularia oryzae carbon dioxide microbubble

维普期刊数据库

Rice Stomatal Closure Requires Guard Cell Plasma Membrane ATP-Binding Cassette Transporter RCN1/OsABCG5

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2016年第3期9卷 417-427页

作者： shuichi Matsuda Sho Takano Moeko sato Kaoru Furukawa Hidetaka Nagasawa Shoko Yoshikawa Jun Kasuga Yoshihiko Tokuji Kazufumi Yazaki Mikio Nakazono Itsuro Takamure Kiyoaki Kato Department of Agro-environmental Science Obihiro University of Agricultural and Veterinary Medicine 2-11 Nishi Inada Obihiro Hokkaido 080-0834 Japan Department of Food Science Obihiro University of Agricultural and Veterinary Medicine 2-11 Nishi Inada Obihiro Hokkaido 080-0834 Japan Research Institute for Sustainable Humanosphere Kyoto University Gokasho Uji Kyoto 611-0011 Japan Graduate School of Bioagricultural Sciences Nagoya University Furo-cho Chikusa Nagoya Aichi 464-8601 Japan Graduate School of Agriculture Hokkaido University Kita 9 Nishi 9 Kita-ku Sapporo Hokkaido 060-8589 Japan

Water stress is one of the major environmental stresses that affect agricultural production worldwide. Water loss from plants occurs primarily through stomatal pores. Here, we report that an Oryza sativa half-size ATP-binding cassette （ABC） subfamily G protein, RCN 1/OsABCG5, is involved in stomatal closure mediated by phytohormone abscisic acid （ABA） accumulation in guard cells. We found that the GFP-RCN1/ OsABCG5-fusion protein was localized at the plasma membrane in guard cells. The percentage of guard cell pairs containing both ABA and GFP-RCN1/OsABCG5 increased after exogenous ABA treatment, whereas they were co-localized in guard cell pairs regardless of whether exogenous ABA was applied. ABA application resulted in a smaller increase in the percentage of guard cell pairs containing ABA in rcnl mutant （A684P） and RCN1-RNAi than in wild-type plants. Furthermore, polyethylene glycol （drought stress）-inducible ABA accumulation in guard cells did not occur in rcnl mutants. Stomata closure mediated by exogenous ABA application was strongly reduced in rcnl mutants. Finally, rcnl mutant plants had more rapid water loss from detached leaves than the wild-type plants. These results indicate that in response to drought stress, RCN1/OsABCG5 is involved in accumulation of ABA in guard cells, which is indispensable for stomatal closure.

关键词： stomatal closure abscisic acid ABC transporter rice drought stress

Who needs further evaluations to diagnose upper urinary tract urothelial cancers among patients with abnormal findings by enhanced CT?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Urology 2016年第1期3卷 44-48页

作者： Akio Takayanagi Atsushi Takahashi Fumimasa Fukuta Manabu Okada Masahiro Matsuki Shunsuke sato Teruhisa Uehara shuichi Kato Yoshio Takagi Department of Urology Hakodate Goryoukaku HospitalHakodateHokkaidoJapan Department of Urology Sapporo Medical University School of MedicineSapporoHokkaidoJapan

Objective:We evaluated who would need further evaluations such as retrograde pyelography(RP)and/or ureteroscopy to diagnose upper urinary tract urothelial cancers(UUTUCs)when abnormal findings for the upper urinary tract(UUT)were detected by enhanced computed tomography(CT).Methods:We retrospectively analyzed 125 patients who underwent enhanced CT for various reasons and had abnormal findings for the UUT.Patients whose tumors were suspected to be of extraureteral origin were excluded.All patients received RP and/or ureteroscopy to evaluate the UUTUCs.Results:The median age of the 125 patients was 70 years and gross hematuria(26.4%)was the most frequently observed symptoms.RP,ureteroscopy and both were performed for 121,59 and 55 patients,respectively.CT revealed tumor-like lesions in 58 patients and the other patients had non-tumor-like lesions.UUTUCs were found in 43(34.4%)of the 125 patients.All of them had tumor-like lesions on CT.In 58 patients who had tumor-like lesions on CT,univariate and multivariate analyses revealed that tumor diameter and tumor enhancement were significant predictive factors for UUTUCs.ROC curve analysis of enhanced CT to diagnose UUTUCs revealed that a tumor diameter of 18 mm was the best cutoff point.The sensitivity,specificity and accuracy were 90.0%,98.8% and 92.7% for RP and 95.5%,100% and 97.1%for ureteroscopy,respectively.Both of them had high sensitivity,specificity and accuracy.Conclusion:We should decide to evaluate the UUT according to the tumor diameter on enhanced CT.When we evaluate the UUT in patients with tumor diameters of less than 20 mm,ureteroscopy is recommended.

关键词： Upper urinary tract urothelial cancers Enhanced CT Ureteroscopy Retrograde pyelography

Clinicopathological study of primary biliary cirrhosis with nterface hepatitis compared to autoimmune hepatitis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第13期20卷 3597-3608页

作者： Mio Kobayashi Yuko Kakuda Kenichi Harada Yasunori sato Motoko Sasaki Hiroko Ikeda Mitsuhiro Terada Munenori Mukai shuichi Kaneko Yasuni Nakanuma Department of Human Pathology Kanazawa University Graduate School of MedicineKanazawa 920-8640Japan Division of Pathology Kanazawa University HospitalKanazawa 920-8641Japan Department of Gastroenterology Kouseiren Takaoka HospitalTakaoka 933-8555Japan Department of Pathology Kouseiren Takaoka HospitalTakaoka 933-8555Japan Department of Gastroenterology Kanazawa University Graduate School of MedicineKanazawa 920-8640 Japan

AIM:To investigate histological and immunohistochemical differences in hepatitis between autoimmune hepatitis(AIH)and primary biliary cirrhosis(PBC)with AIH features.METHODS:Liver needle biopsies of 41 PBC with AIH features and 43 AIH patients were examined.The activity of periportal and lobular inflammation was scored0(none or minimal activity)to 4(severe),and the degree of hepatitic rosette formation and emperipolesis was semiquantatively scored 0-3.The infiltration of mononuclear cells positive for CD20,CD38,CD3,CD4,and CD8 and positive for immunoglobulins(IgG,IgM,and IgA)at the periportal areas(interface hepatitis)and in the hepatic lobules(lobular hepatitis)were semiquantitatively scored in immunostained liver sections(score 0-6).Serum aspartate aminotransferase(AST),immunoglobulins,and autoantibodies at the time of liver biopsy were correlated with the histological and immunohistochemical scores of individual lesions.RESULTS:Lobular hepatitis,hepatitic rosette formation,and emperipolesis were more extensive and frequent in AIH than in PBC.CD3+,CD4+,and CD8+cell infiltration scores were higher in the hepatic lobules and at the interface in AIH but were also found in PBC.The degree of mononuclear cell infiltration correlated well with the degree of interface and lobular hepatitis in PBC,but to a lesser degree in AIH.CD20+cells were mainly found in the portal tracts and,occasionally,at the interface in both diseases.Elevated AST correlated well with the hepatocyte necroinflammation and mononuclear cell infiltration,specifically CD38+cells in PBC.No correlation existed between autoantibodies and inflammatory cell infiltration in PBC or AIH.While most AIH cases were IgG-predominant at the interface,PBC cases were divided into IgM-predominant,IgM/IgGequal,and IgG-predominant types,with the latter sharing several features with AIH.CONCLUSION:These results suggest that the hepatocellular injuries associated with interface and lobular hepatitis in AIH and PBC with interface hepatitis may not be identical.

关键词： Primary biliary cirrhosis Autoimmune hepa-titis In

Erratum to: Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2022年第5期15卷 4773-4773页

The article“Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure”,written by Tsukasa Akasaka,Miho Tamai,Yoshitaka Yoshimura,Natsumi Ushijima,Shinichiro Numamoto,Atsuro Yokoyama,Hirofumi Miyaji,Ryo Takata,shuichi Yamagata,Yoshiaki sato,Ko Nakanishi,and Yasuhiro Yoshida,was originally published electronically on the publisher’s internet portal on January 17,2022 without open access.

关键词： internet portal Nat