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瓦斯涌出量灰色-RBF网络模型的建立与应用

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中国矿业 2016年第10期25卷 107-109,127页

作者：张水曹庆贵王帅山东科技大学矿业与安全工程学院山东青岛266590

为了减少瓦斯事故给煤矿生产带来的损失,本文在灰色模型预测煤矿瓦斯涌出量的基础上,结合神经网络理论,构建了灰色-RBF网络模型,充分利用灰色模型的"小样本、贫信息"的预测特点及RBF神经网络自学习、自适应能力特点。首先使用灰色模型... 详细信息

为了减少瓦斯事故给煤矿生产带来的损失,本文在灰色模型预测煤矿瓦斯涌出量的基础上,结合神经网络理论,构建了灰色-RBF网络模型,充分利用灰色模型的"小样本、贫信息"的预测特点及RBF神经网络自学习、自适应能力特点。首先使用灰色模型对瓦斯涌出量进行初步预测,然后建立RBF网络模型进行再次预测,得到瓦斯涌出量的最终预测值;RBF网络模型的训练和预测计算用MATLAB软件完成。通过对安徽省某矿瓦斯涌出量的预测结果对比,灰色-RBF网络模型的预测误差分别为0.325和0.221,灰色模型预测误差为2.51和2.45,结果表明灰色-RBF网络模型预测明显高于单一灰色模型预测的预测精度。为煤矿瓦斯涌出量预测提供一种预测精度高的方法。

关键词：瓦斯灰色系统 RBF神经网络 MATLAB

铝电解阳极气泡动力学及分布特性的低温电解实验研究

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中国有色金属学报 2017年第12期27卷 2605-2614页

作者：詹水清王贞涛杨建红郑俊王军锋江苏大学能源与动力工程学院镇江212013 江苏大学绿色材料与冶金研究院镇江212013

以河南某厂300 k A铝电解槽为原型,基于相似原理,按与原型1:4的几何比例设计和搭建大尺度低温电解实验平台,探讨和分析阳极底掌气泡的成核、长大、聚并、破碎及分离等动力学行为及分布特性规律。结果表明:阳极底掌成核点处首先主要产生... 详细信息

以河南某厂300 k A铝电解槽为原型,基于相似原理,按与原型1:4的几何比例设计和搭建大尺度低温电解实验平台,探讨和分析阳极底掌气泡的成核、长大、聚并、破碎及分离等动力学行为及分布特性规律。结果表明:阳极底掌成核点处首先主要产生尺寸极小且分布比较均匀的气泡,然后这些气泡在扩散和传质引起的生长及碰撞和"吞噬"引起的聚并过程中不断长大,最后在阳极底掌边缘发生一定的分离与破碎过程,同时还伴随着较强烈的液体局部循环扰动。阳极底掌气泡层内气泡的尺寸分布范围比较宽且形状差异较大,数量比较少的大尺寸及中等尺寸气泡的周围存在着数量比较多的小尺寸气泡。改变电流密度和阳极倾斜角均对上述气泡的相关动力学行为和尺寸分布特性有着重要的影响。

关键词：铝电解阳极气泡动力学分布特性低温电解实验研究

ELEMENT ANALYSIS IN THE TOOTH OF Stegodon huanghoensis

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Chinese Science Bulletin 1989年第10期34卷 877-879页

作者：宋世战杨化中谷祖纲水永清王连宾雷桂林 Lanzhou University Lanzhou Normal College

Of all the fossils of Stegodon that have been found in the world up to now, Stegodon huanghoensis found in Heshui County, Gansu Province in 1973, is the most intact one. It belongs to the early Pleistocene and is now ... 详细信息

关键词： preserved Pleistocene fossil intact teeth belongs bones mammalian abundant Gansu

Bowel preparation before colonoscopy: Consequences, mechanisms, and treatment of intestinal dysbiosis

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World Journal of Gastroenterology 2025年第2期31卷 13-26页

作者： Ze-Long Zheng qing-Fan Zheng Li-Qiang wang Yi Liu Department of Gastroenterology(Endoscopy Center) China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

The term“gut microbiota”primarily refers to the ecological community of various microorganisms in the gut,which constitutes the largest microbial community in the human *** adequate bowel preparation can improve the results of colonoscopy,it may interfere with the gut *** preparation for colonoscopy can lead to transient changes in the gut microbiota,potentially affecting an individual’s health,especially in vulnerable populations,such as patients with inflammatory bowel ***,measures such as oral pro-biotics may ameliorate these adverse *** focused on the bowel prepa-ration-induced changes in the gut microbiota and host health status,hypothesized the factors influencing these changes,and attempted to identify measures that may reduce dysbiosis,thereby providing more information for individualized bowel preparation for colonoscopy in the future.

关键词： Bowel preparation Colonoscopy Microbiota Inflammatory bowel disease Probiotics

Effect of pyrite content on chalcopyrite flotation under different regrinding conditions

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 49-57页

作者： Zejun wang qing Shi Guofan Zhang Yuxuan Zhu Binbin Li School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China

This study aimed to investigate the effect of varying pyrite(Py)content on copper(Cu)in the presence of different regrinding conditions,which were altered using different types of grinding media:iron,ceramic balls,and their mixture,followed by flotation in the cleaner *** flotation performance of rough Cu concentrate can be improved by changing the regrinding conditions based on the Py *** electron microscopy,X-ray spectrometry,ethylenediaminetetraacetic acid disodium salt extraction,and X-ray photoelectron spectroscopy studies illustrated that when the Py content was high,the use of iron media in regrinding promoted the generation of hydrophilic Fe OOH on the surface of Py and improved the Cu *** ceramic medium with a low Py content prevented excessive Fe OOH from covering the surface of chalcopyrite(Cpy).Electrochemical studies further showed that the galvanic corrosion current of Cpy-Py increased with the addition of Py and became stronger with the participation of iron media.

关键词： chalcopyrite regrinding media pyrite galvanic corrosion flotation

Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2

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Neural Regeneration Research 2025年第6期20卷 1801-1815页

作者： qing He Zhen wang Yuchen wang Mengjie Zhu Zhile Liang Kanghong Zhang Yuge Xu Gong Chen GHM Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina

Direct in vivo conversion of astrocytes into functional new neurons induced by neural transcription factors has been recognized as a potential new therapeutic intervention for neural injury and degenerative disorders. However, a few recent studies have claimed that neural transcription factors cannot convert astrocytes into neurons, attributing the converted neurons to pre-existing neurons mis-expressing transgenes. In this study, we overexpressed three distinct neural transcription factors––NeuroD1, Ascl1, and Dlx2––in reactive astrocytes in mouse cortices subjected to stab injury, resulting in a series of significant changes in astrocyte properties. Initially, the three neural transcription factors were exclusively expressed in the nuclei of astrocytes. Over time, however, these astrocytes gradually adopted neuronal morphology, and the neural transcription factors was gradually observed in the nuclei of neuron-like cells instead of astrocytes. Furthermore,we noted that transcription factor-infected astrocytes showed a progressive decrease in the expression of astrocytic markers AQP4(astrocyte endfeet signal), CX43(gap junction signal), and S100β. Importantly, none of these changes could be attributed to transgene leakage into preexisting neurons. Therefore, our findings suggest that neural transcription factors such as NeuroD1, Ascl1, and Dlx2 can effectively convert reactive astrocytes into neurons in the adult mammalian brain.

关键词： aquaporin-4 Ascl1 astrocyte cortex Dlx2 gap junction glia-to-neuron conversion neural regeneration NeuroD1 reprogramming

晚期非小细胞肺癌p53和ERCC1表达状态与顺铂为主的联合方案化疗的近期有效率的相关性研究

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现代生物医学进展 2012年第5期12卷 876-879页

作者：鞠放汪青清水汪孟蓉蓉王雅杰上海第二军医大学附属长海医院肿瘤科上海200433

目的:研究晚期非小细胞肺癌不同的p53和ERCC1表达状态与基于顺铂为主的姑息化疗近期有效率的相关性。方法:对经顺铂联合多西他赛或顺铂联合吉西他滨治疗的48例晚期非小细胞肺癌患者进行回顾性分析,利用既往免疫组化资料,观察基于顺铂为... 详细信息

目的:研究晚期非小细胞肺癌不同的p53和ERCC1表达状态与基于顺铂为主的姑息化疗近期有效率的相关性。方法:对经顺铂联合多西他赛或顺铂联合吉西他滨治疗的48例晚期非小细胞肺癌患者进行回顾性分析,利用既往免疫组化资料,观察基于顺铂为主的方案近期有效率(RR)的影响因素及化疗不良反应。结果:全组48例患者均完成至少两周期化疗,并行疗效评价。该组患者化疗的近期有效率为28例(58.3%),RR与不同的转移病灶部位(P=0.042)及病灶数目(P=0.034)有显著差异。该类方案的近期有效率与ERCC1状态(P=0.012)密切相关,而与p53表达状态(P=0.401)无关。毒性反应主要是骨髓抑制、脱发及消化道反应等。结论:晚期非小细胞肺癌ERCC1阴性患者较ERCC1阳性患者运用顺铂为主的联合方案化疗的近期有效率较高。ERCC1可能是顺铂疗效预测的敏感因子。p53的表达状态可能不是该类方案的疗效预测因子。

关键词：非小细胞肺癌顺铂 ERCC1基因 p53

SUPG finite element method based on penalty function for lid-driven cavity flow up to Re = 27500

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Acta Mechanica Sinica 2016年第1期32卷 54-63页

作者： Da-Guo wang qing-Xiang shui School of Environment and Resources Southwest University of Science and Technology

A streamline upwind/Petrov-Galerkin （SUPG） finite element method based on a penalty function is pro- posed for steady incompressible Navier-Stokes equations. The SUPG stabilization technique is employed for the for- mulation of momentum equations. Using the penalty function method, the continuity equation is simplified and the pres- sure of the momentum equations is eliminated. The lid-driven cavity flow problem is solved using the present model. It is shown that steady flow simulations are computable up to Re = 27500, and the present results agree well with previous solutions. Tabulated results for the properties of the primary vortex are also provided for benchmarking purposes.

关键词： Streamline upwind/Petrov-Galerkin (SUPG)finite element method Lid-driven cavity flow Penaltyfunction method High Reynolds number

Association between autoimmune gastritis and gastric polyps:Clinical characteristics and risk factors

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 73-87页

作者： Jing-Zheng Jin Xiao Liang Shu-Peng Liu Rui-Lan wang qing-Wei Zhang Yu-Feng Shen Xiao-Bo Li Division of Gastroenterology and Hepatology Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Division of Gastroenterology and Hepatology Shanghai Institute of Digestive DiseasesShanghai 200001China Division of Gastroenterology and Hepatology Renji Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200127China Division of Gastroenterology and Hepatology Sichuan Armed Police Corps HospitalLeshan 610041Sichuan ProvinceChina Division of Gastroenterology and Hepatology NHC Key Laboratory of Digestive DiseasesRenji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Department of Gastroenterology Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Institute of Digestive DiseasesShanghai 200127China

BACKGROUND The relationship between autoimmune gastritis(AIG)and gastric polyps(GPs)is not well *** To explore the clinical characteristics and risk factors of AIG with GPs in *** This double center retrospective study included 530 patients diagnosed with AIG from July 2019 to July *** collected clinical,biochemical,serological,and demographic data were of each *** regression analyses,both multivariate and univariate,were conducted to pinpoint independent risk factors for GPs in patients with AIG *** operating characteristic curves were utilized to establish the optimal cutoff values,sensitivity,and specificity of these risk factors for predicting GPs in patients with *** Patients with GPs had a higher median age than those without GPs[61(52.25-69)years vs 58(47-66)years,P=0.006].The gastrin-17 levels were significantly elevated in patients with GPs compared with those without GPs[91.9(34.2-138.9)pmol/mL vs 60.9(12.6-98.4)pmol/mL,P<0.001].Additionally,the positive rate of parietal cell antibody(PCA)antibody was higher in these patients than in those without GPs(88.6%vs 73.6%,P<0.001).Multivariate and univariate analyses revealed that PCA positivity[odds ratio(OR)=2.003,P=0.017],pepsinogen II(OR=1.053,P=0.015),and enterochromaffin like cells hyperplasia(OR=3.116,P<0.001)were significant risk factors for GPs,while pepsinogen I was identified as a protective *** PCA positivity and enterochromaffin like cells hyperplasia are significant risk factor for the development of GPs in patients with *** gastrin-17 levels may also play a role in this *** findings suggest potential targets for further research and therapeutic intervention in managing GPs in patients with AIG.

关键词： Autoimmune gastritis Gastric polyps Neuroendocrine tumor Risk factors Nomogram