检索结果-南通市图书馆

Nano Research 2023年第4期16卷 4678-4684页

作者： Minghua Li Jinxing Chen Weiwei wu shuangli wu Lili Xu Shaojun Dong College of Chemistry Jilin UniversityChangchun 130012China State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China University of Science and Technology of China Hefei 230026China

Atomically dispersed catalysts have been widely studied due to their high catalytic activity and atom utilization.Single-atom catalysts have achieved breakthrough progress in the degradation of emerging organic contaminants(EOCs)by activating peroxymonosulfate(PMS).However,the construction of atomically dispersed catalysts with diatomic/multiatomic metal active sites by activating PMS to degrade pollutants is still seldom reported,despite the unique merits of atom-pair in synergistic electronic modulation and breaking stubborn restriction of scaling relations on catalytic activity.We have synthesized Fe1-N-C,Fe_(2)-N-C,and Fe_(3)-N-C catalysts with monoatomic iron,diatomic iron,and triatomic iron active center,respectively.The results show that the catalytic degradation activity of Fe_(2)-N-C is twice that of Fe1-N-C and Fe_(3)-N-C due to its unique Fe_(2)N6 coordination structure,which fulfilled the complete degradation of rhodamine B(RhB),bisphenol A(BPA),and 2,4-dichlorophenol(2,4-DP)within 2 min.Electron paramagnetic resonance(EPR)and radical quenching experiments confirmed that the reaction was a nonradical reaction on the catalyst surface.And singlet oxygen and Fe(IV)are the key active species.

关键词： diatomic catalyst peroxymonosulfate nonradical contaminant

Atomically dispersed hierarchically ordered porous Fe-N-C single-atom nanozymes for dyes degradation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2023年第8期16卷 10840-10847页

作者： shuangli wu Weiwei wu Xinyang Zhu Minghua Li Jianguo Zhao Shaojun Dong Changchun State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China University of Science and Technology of China Hefei 230026China College of Chemistry Jilin UniversityChangchun 130012China

The development of novel nanozymes for environmental contamination remediation is a worthwhile research direction.However,most of the reported nanozymes cannot degrade efficiently due to the limitation of the internal active sites not being able to come into direct contact with contaminants.Therefore,we reported Fe-N-C single-atom nanozymes(SAzymes)with atomically dispersed FeN4 active sites anchored on a three-dimensional hierarchically ordered microporous-mesoporous-macroporous nitrogen doped carbon matrix(3DOM Fe-N-C)for the degradation of a targeted environmental pollutant(rhodamine B(RhB)).The three-dimensional(3D)hierarchically ordered porous structure may accelerate mass transfer and improve the accessibility of active sites.This structure and high metal atom utilization endow Fe-N-C SAzyme with enhanced tri-enzyme-mimic activities,comprising oxidase-mimic,peroxidase-mimic,and catalase-mimic activities.Based on its excellent peroxidase-mimic activity,3DOM Fe-N-C can degrade RhB by hydroxyl radicals(·OH)generated in the presence of hydrogen peroxide.This study provides a new idea for designing porous Fe-N-C SAzymes for environmental contamination remediation.

关键词： single-atom nanozymes(SAzymes) metal organic frameworks(MOFs) hierarchically ordered porous structure trienzyme mimics environmental contamination remediation

基于TCGA数据库肺腺癌自噬相关基因预后模型的建立与验证

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

现代医药卫生 2024年第10期40卷 1621-1626页

作者：吴双丽吴铁成喻光徐敬宣李保健邢龙青岛滨海学院附属医院神经电生理科山东青岛266500 青岛滨海学院附属医院肿瘤内科山东青岛266500

目的探究肺腺癌自噬相关基因(ARGs),并构建肺腺癌ARGs的预后模型。方法肺腺癌的RNA高通量转录组数据下载于癌症基因组图谱(TCGA)数据库和人类自噬基因(HADb)数据库,获取ARGs,并基于肺腺癌差异表达ARGs构建肺腺癌预后模型并验证,进一步... 详细信息

目的探究肺腺癌自噬相关基因(ARGs),并构建肺腺癌ARGs的预后模型。方法肺腺癌的RNA高通量转录组数据下载于癌症基因组图谱(TCGA)数据库和人类自噬基因(HADb)数据库,获取ARGs,并基于肺腺癌差异表达ARGs构建肺腺癌预后模型并验证,进一步构建列线图及校准曲线探究模型在临床中的应用价值。对差异表达ARGs进行基因本体和京都基因与基因组百科全书富集分析。对获得的具有预后意义的差异表达ARGs进行Lasso回归分析并构建肺腺癌预后模型。绘制Kaplan-Meier生存曲线。结果共获得31个差异表达ARGs,筛选得到10个具有预后意义的差异表达ARGs。高风险组患者与较差的总生存期明显相关,差异有统计学意义(P<0.05)。T分期、N分期、风险评分为肺腺癌患者的独立预后因素。校准曲线和列线图全局一致性为0.710,说明模型预测结果与实际情况具有较高的符合度。结论基于差异表达ARGs构建的风险模型可作为肺腺癌患者的一种预后特征或可为肺腺癌患者的个体化治疗提供参考依据。

关键词：肺腺癌自噬相关基因预后模型癌症基因组图谱数据库计算生物学

旭龙水电站大坝安全监测信息综合管理系统设计研究

在线全文

学校读者我要写书评

暂无评论

水利水电快报 2024年第5期45卷 105-110,116页

作者：刘光彪李少林吴双利纪传波戴领沈明毅长江勘测规划设计研究有限责任公司湖北武汉430010 国家大坝安全工程技术研究中心湖北武汉430010 国家能源集团金沙江旭龙水电有限公司四川成都610041

为提高安全监测作业工作效率,满足其快速、高效、可靠地掌握工程性态的需要,需通过信息化手段设计与研发旭龙水电站大坝安全监测信息综合管理系统。依据旭龙水电站安全监测需求,以工程安全监测具体业务为导向,综合考虑各参建单位的使用... 详细信息

为提高安全监测作业工作效率,满足其快速、高效、可靠地掌握工程性态的需要,需通过信息化手段设计与研发旭龙水电站大坝安全监测信息综合管理系统。依据旭龙水电站安全监测需求,以工程安全监测具体业务为导向,综合考虑各参建单位的使用场景,开发了监测管理系统,包含定制化首页、工程管理、施工管理、在线采集、环境信息、仪器管理、监测管理、资料分析、监测预警、巡视检查、报表报告、三维展示等功能,并在监测管理系统中保留符合智慧工程、智慧电厂系统要求的接口,满足相关数据传输与信息推送要求。通过使用监测管理系统,提升了工作效率,降低了工程安全隐患风险。研究成果可为类似大坝安全监测系统设计提供参考。

关键词：安全监测安全监测信息综合管理系统智慧工程旭龙水电站

Molecular Cloning and Putative Functions of KIFC1 for Acrosome Formation and Nuclear Reshaping during Spermiogenesis in Schlegel’s Japanese Gecko Gekko japonicus

在线全文

学校读者我要写书评

暂无评论

Asian Herpetological Research 2019年第3期10卷 170-182页

作者： shuangli HAO Liyue ZHANG Jun PING Xiaowen wu Jianrao HU YongpuZHANG College of Life and Environmental Sciences Wenzhou UniversityWenzhou325035China College of Medicine Zhejiang UniversityHangzhou310058China College of Life and Environmental Sciences Hangzhou Normal UniversityHangzhou310036China

Spermiogenesis, occurring in the male testis, is a complicated and highly-ordered developmental process resulting in the production of fertile mature sperm. In Gekko japonicus, this process occurs in 7 steps during which the spermatids undergo dramatic changes in the cytoskeleton and nucleus. Here, we cloned and sequenced the cDNA of the mammalian KIFC1 homologue in the testis of G. japonicus. The 2 344 bp full-length cDNA sequence contained a 191 bp 5’-untranslated region, a 134 bp 3’-untranslated region and a 2 019 bp open reading frame encoding a protein of 672 amino acids. Tissue expression analysis revealed the highest expression of kifc1 mRNA was in the testis. Fluorescence in situ hybridization revealed that the kifc1 mRNA signal was hardly detected in step 1 spermatids but became concentrated at the acrosome of step 2 spermatids and abundant in the nucleus of step 5 spermatids where the nucleus then undergoes dramatic elongation and compression. The kifc1 mRNA signal then gradually disappears in mature sperm. This expression of KIFC1 at specific stages of spermiogenesis in G. japonicus implies its important role in the major cytological transformations such as acrosome biogenesis and nucleus morphogenesis.

关键词： Spermiogenesis KIFC1 Kinesin Gekko japonicus

Analysis of the distribution characteristics of enterovirus types based on environmental surveillance from 2013 to 2021 in Fujian Province, China

在线全文

学校读者我要写书评

暂无评论

生物安全与健康(英文) 2023年第4期5卷 240-249页

作者： Xiuhui Yang Shaojian Cai Xiaoqian wu Yong Zhang Dong Li Yahong Chen Qianjing Chen shuangli Zhu Dongmei Yan Wenbo Xu Hairong Zhang Zhifei Chen Suhan Zhang Yong Zhou Mengping Zhang Ningxuan Zheng Na You Fujian Province Key Laboratory of Zoonosis Research Fujian Center for Disease Control and PreventionFuzhou 350012China School of Basic Medical Sciences Fujian Medical UniversityFuzhou 350108China WHO WPRO Regional Polio Reference Laboratory and Ministry of Health Key Laboratory for Medical Virology National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionChangping DistrictBeijing 102206China Quanzhou Center for Disease Control and Prevention Quanzhou 362018China Longyan Center for Disease Control and Prevention Longyan 364000China Public Health School of Fujian Medical University Fuzhou 350108China

Environmental surveillance (ES) is a useful approach for monitoring circulating viruses, including polioviruses (PVs) and non-polio enteroviruses (NPEVs). In this study, the results of nine years of ES from 2013 to 2021 at six sampling sites in three cities in Fujian Province, China, were summarized. It showed that the sewage samples contained abundant viruses, but the positive rate was affected by different sampling sites. From the 520 samples, 431 PVs, 1,713 NPEVs, and 281 human adenoviruses (HAdVs) were isolated. PV isolates had been markedly affected following the adjustment of the immunization strategy. All but one PV isolate were Sabin-like strains without wild PVs. One isolate was vaccine-derived PV type 3 with 10 variation points in theVP1 region. After May 2016, PV type 2 was no longer detected, and PV type 3 became a superior serotype. Of 1,713 NPEVs, 24 serotypes were identified, including echovirus11 (E11), E6, coxsackievirus B3 (CVB3), CVB5, E7, and E3 were the predominant serotypes (37.65%, 20.96%, 11.50%, 8.87%, 8.23%, and 7.06%, respectively). The temporal dynamic of the six common serotypes was inconsistent. E3 was frequently isolated, but the number of isolates was low, with no obvious peaks. E6, E7, and CVB3 exhibited periodic changes with a high peak every three to four years, and E11 only had one high peak lasting four years. Summer-fall peaks of the echoviruses and spring-winter peaks of CVB were observed in the monthly distribution of virus isolation. The infectious isolates of various serotypes of different species identified from the sewage samples showed that ES is an essential part of pathogen surveillance.

关键词： Enterovirus surveillance Enteroviruse Poliovirus Distribution characteristics

Isolation of 2019-nCoV from a Stool Specimen of a Laboratory- Confirmed Case of the Coronavirus Disease 2019 (COVID-19)

在线全文

学校读者我要写书评

暂无评论

China CDC weekly 2020年第8期2卷 123-124页

作者： Yong Zhang Cao Chen shuangli Zhu Chang Shu Dongyan Wang Jingdong Song Yang Song Wei Zhen Zijian Feng Guizhen wu Jun Xu Wenbo Xu National Health Commission Key Laboratory for Medical Virology National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina Heilongjiang Center for Disease Control and Prevention HaerbinChina Chinese Center for Disease Control and Prevention BeijingChina

The novel coronavirus(2019-nCoV)is spreading very fast in Hubei Province of China.As of February 14,2020,51,986 confirmed cases(including laboratory-confirmed cases and clinically-confirmed cases)were reported in Hubei Province,and 1,318 of them died.Respiratory droplets and contact transmission are considered to be the most important routes of transmission of 2019-nCoV,but do not fully account for the occurrence of all coronavirus disease 2019(COVID-19)cases,previously known as novel coronavirus pneumonia(NCP),and the reasons for the rapid spread of this virus(1).

关键词： China. fir Hubei

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

环境监测现场采样的质量控制举措和建议

皮革制作与环保科技 2022年第8期3卷 29-31页

作者：乔燕吴双利山东省滨州生态环境监测中心山东滨州256600

现场采样监测作为环境监测的首要环节,是整个环境监测分析工作的前提和基础。采样一旦出现质量问题会直接影响监测结果的准确性,后续监测工作将失去意义。本文对现场采样过程中的影响因素及目前现场采集水、气、固体等不同样品时的注意... 详细信息

现场采样监测作为环境监测的首要环节,是整个环境监测分析工作的前提和基础。采样一旦出现质量问题会直接影响监测结果的准确性,后续监测工作将失去意义。本文对现场采样过程中的影响因素及目前现场采集水、气、固体等不同样品时的注意事项进行了逐一分析,并结合自身多年现场监测工作经验从采样前准备、采样中及采样后等环节进行质量控制举措的探讨,提出了现场采样改进建议,从源头开始提高监测数据质量。

关键词：环境监测现场采样质量控制

在线全文

学校读者我要写书评

暂无评论

新时代“大思政”格局下高校党建带团建探析

承德石油高等专科学校学报 2024年第1期26卷 70-72页

作者：田晓杨玉怡吴函阳河北旅游职业学院河北承德067000

新时代高校思想政治工作有很多新任务和新举措,深入剖析了原有党建带团建工作所存在的问题,制约“双立双成”育人模式的发挥。阐明了新时代“大思政”格局下高校党建带团建,有利于提升党团组织凝聚力,扩大党团组织的影响力,增强党团组... 详细信息

新时代高校思想政治工作有很多新任务和新举措,深入剖析了原有党建带团建工作所存在的问题,制约“双立双成”育人模式的发挥。阐明了新时代“大思政”格局下高校党建带团建,有利于提升党团组织凝聚力,扩大党团组织的影响力,增强党团组织的战斗力。总结了新时代“大思政”格局下高校党建带团建嵌入联动、精准回应和链条执行三条新路径。

关键词：新时代大思政党建带团建新路径

在线全文

学校读者我要写书评

暂无评论

“十三五”期间滨州市城市空气质量状况分析

黑龙江环境通报 2022年第2期35卷 48-49页

作者：吴双利乔燕山东省滨州生态环境监测中心山东滨州256600

基于“十三五”期间滨州市国控空气自动监测站自动监测数据,分析了滨州市城市空气质量状况。结果表明:“十三五”期间,滨州市空气质量总体好于“十二五”水平,PM_(10)、PM_(2.5)、SO_(2)、CO-95per呈逐年下降趋势,NO_(2)浓度基本稳定,... 详细信息

基于“十三五”期间滨州市国控空气自动监测站自动监测数据,分析了滨州市城市空气质量状况。结果表明:“十三五”期间,滨州市空气质量总体好于“十二五”水平,PM_(10)、PM_(2.5)、SO_(2)、CO-95per呈逐年下降趋势,NO_(2)浓度基本稳定,未见明显改善;O_(3)-8h-90per出现上升趋势。滨州市PM_(2.5)、O_(3)、PM_(10)在超标天数中的占比较大,PM_(2.5)和PM_(10)的影响逐年下降,O_(3)对超标天数的影响越来越大。影响滨州市空气质量的主要污染物仍是PM_(2.5)、PM_(10),NO_(2)和O_(3)的占比影响逐年增高,SO_(2)减排效果显著。需进一步分析大气污染成因,进行综合性治理,提升大气环境质量。

关键词：十三五滨州市空气质量 PM2.5