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Journal of Ocean University of China 2024年第4期23卷 1035-1044页

作者： ZHU ying YANG Xinsheng li Zhengjie li Chao School of Marine Science and Engineering Qingdao Agricultural UniversityQingdao 266109China

As a member of mucins family,MUC2 is an important component of mucus,which is characterized by tandem and irregular repeat sequences rich in threonine and *** is strongly expressed by goblet cells that are involved in innate *** flounder is an economically important marine *** this study,two homologous genes of MUC2 were identified,named MUC2-1 and *** on phylogenetic and structural analysis,MUC2-1 and MUC2-2 were clustered in two clades,*** olivaceus MUC2-1 showed a closer relationship with MUC2 in the higher *** healthy tissues were analyzed to determine the expression patterns,and both MUC2 genes showed high expression levels in the gills and *** Edwardsiella tarda challenge,*** MUC2-1 and MUC2-2 both showed significant up-regulated expression in intestine and ***,MUC2-1 was significantly up-regulated in gill cell lines following PGN and polyI:C stimulation,and MUC2-2 was significantly up-regulated in gill cell lines following LPS *** addition,ISH results revealed that MUC2-1 and MUC2-2 showed the same tissue localization in intestine tissues,but displayed different localization in *** siRNA-mediated knockdown of MUC2-1 and MUC2-2 genes in the gill cell lines of Japanese flounder affected the expressions of galnt family genes and smad pathway members that are related to mucosal *** results provided a valuable insight into understanding the functions of MUC2 on mucosal immune system in response to the invasion of bacterial pathogen.

关键词： MUC2 ISH Edwardsiella tarda Paralichthys olivaceus

The joint Laplace transforms for killed diffusion occupation times

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Applied Mathematics(A Journal of Chinese Universities) 2024年第3期39卷 398-415页

作者： li ying-qiu CHEN Ye School of Mathematics and Statistics Changsha University of Science and TechnologyChangsha 410114China College of Mathematics and Computational Science Hunan University of Arts and ScienceChangde 415000China

The approach of li and Zhou(2014)is adopted to find the Laplace transform of occupation time over interval(0,a)and joint occupation times over semi-infinite intervals(-∞,a)and(b,∞)for a time-homogeneous diffusion process up to an independent exponential time e_(q)for 0licit expressions on the Laplace transform of occupation time and joint occupation time for Brownian motion with drift.

关键词： time-homogeneous diffusion process occupation time joint occupation time Laplace transform Brownian motion with drift

Construction of multifunctional lanthanum manganese mixed nanoparticles mediated by ionic liquids for selective aerobic oxidation of cyclohexane

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Rare Metals 2024年第5期43卷 2205-2221页

作者： Hao li Rui-Rui Zhang Ke-Xin li shuang Wei Yu-Mei liu Rui-Xia liu Beijing Key Laboratory of Ionic liquids Clean Process CAS Key Laboratory of Green Process and EngineeringState Key Laboratory of Multiphase Complex SystemsInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

Selective oxidation of alkanes to produce highvalue chemicals is an essential strategy and means to realize efficient utilization of *** this work,a strategy of lanthanum manganese mixed metal oxides(LMMO)regulated via a facile ionic liquid(IL)-assisted hydrothermal method was proposed to construct the multifunctional catalysts,which exhibited excellent catalytic performance in the selective aerobic oxidation of *** 8.9%cyclohexane conversion with 90%KA oi(cyclohexanol and cyclohexanone)selectivity was achieved over the optimal LMMO catalyst under mild *** effects of anion type,carbon chain length and concentration of ILs on the structure and properties of catalysts were investigated through various characterizations,indicating the structure-directing and template effect of ILs on the multifunctional *** formation of self-assembled spherical nanoparticles followed the"dissolution-nucleation-proliferation"mechanism with the introduction of 1-butyl-3-methylimidazolium hydrogen sulfate,ascribing the synergistic effect between the microenvironment of ILs and the hydrothermal ***,the high reactive oxygen concentration redox capacity,and suitable basic sites of LMMO catalysts mediated by ILs enhance the activation of C-H bonds and molecular oxygen,simultaneously influencing the adsorption and desorption of the substrate.A comprehensive understanding of the high KA oil selectivity and radical reaction mechanism was elucidated based on in situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTS)and radical trapping *** recycling and regeneration experiments further illuminated that the removal of adsorbed cyclohexanone acting on the LMMO catalyst was the key to achieve high KA oil selectivity.

关键词： Ionic liquids Nanoparticle Multifunctional catalyst Cyclohexane oxidation

Semi-Varying Coefficient Panel Data Model with Technical Indicators Predicts Stock Returns in Financial Market

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Journal of Systems Science & Complexity 2024年第4期37卷 1638-1652页

作者： HU Xuemei PAN ying li Xiang School of Mathematics and Statistics Chongqing Technology and Business UniversityChongqing 400067China Chongqing Key Laboratory of Social Economy and Applied Statistics Chongqing 400067China Research Center for Economy of Upper Reaches of the Yangtse River Chongqing Technology and Business UniversityChongqing 400067China

Accurately predicting stock returns is a conundrum in financial *** this conundrum can bring huge economic benefits for investors and also attract the attention of all circles of *** this paper the authors combine semi-varying coefficient model with technical analysis and statistical learning,and propose semi-varying coefficient panel data model with individual effects to explore the dynamic relations between the stock returns from five companies:CVX,DFS,EMN,LYB,and MET and five technical indicators:CCI,EMV,MOM,ln ATR,ln RSI as well as closing price(ln CP),combine semi-parametric fixed effects estimator,semi-parametric random effects estimator with the testing procedure to distinguish fixed effects(FE) from random effects(RE),and finally apply the estimated dynamic relations and the testing set to predict stock returns in December 2020 for the five *** proposed method can accommodate the varying relationship and the interactive relationship between the different technical indicators,and further enhance the prediction accuracy to stock returns.

关键词： Fixed effects random effects semi-varying coefficient panel data model stock returns technical indicators

免疫治疗新浪潮下对中国肺癌免疫临床研究的审思

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中国肺癌杂志 2017年第10期20卷 695-702页

作者：柳菁菁张爽李双程颖吉林省肿瘤医院胸部肿瘤内科长春130012

从抗CTLA-4抗体Ipilimumab在恶性黑色素瘤中获得成功开始,靶向免疫检查点的治疗成为抗肿瘤治疗的有效策略之一,掀起了肿瘤免疫治疗研究的新浪潮。在肺癌领域,国外开展了一系列免疫靶向药物的临床研究,Nivolumab、Pembrolizumab和Atezoli... 详细信息

从抗CTLA-4抗体Ipilimumab在恶性黑色素瘤中获得成功开始,靶向免疫检查点的治疗成为抗肿瘤治疗的有效策略之一,掀起了肿瘤免疫治疗研究的新浪潮。在肺癌领域,国外开展了一系列免疫靶向药物的临床研究,Nivolumab、Pembrolizumab和Atezolizumab相继被批准用于肺癌的治疗,改写了肺癌治疗历史。在中国,也相继开展了肺癌免疫靶向药物的临床研究,本文主要对中国肺癌免疫研究的现状、差距和未来如何创新进行了分析和探讨。

关键词：肺肿瘤免疫检查点免疫治疗

Anomalies of Precipitation over China on Days with Tropical Cyclone Activity over the Bay of Bengal: Role of Moisture Transport

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Journal of Meteorological Research 2024年第2期38卷 368-382页

作者： Na WEI ying li Xiaoting FAN Nanjing Joint Institute for Atmospheric Sciences Nanjing 210041 State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesChina Meteorological AdministrationBeijing 100081 Department of Atmospheric and Oceanic Sciences and Institute of Atmospheric Sciences Fudan UniversityShanghai 200433

Tropical cyclones over the Bay of Bengal(BoBTC)affect the precipitation over China,with distinct seasonal and daily *** study quantitatively examines the daily standardized precipitation anomalies(SPAs)over China on the days with BoBTC activities(storm-days)and related circulations,based on rainfall measurements at surface meteorological stations and ECMWF reanalysis data on a 0.25°×0.25°resolution during *** positive SPA is found over the stations in the two adjacent regions around BoB(Southwest China in May/November and southern Tibetan Plateau in October)and three distant regions(Southeast China and the northeastern boundary of the Qinghai-Tibet Plateau in May,and central North China in October).The SPA distributions are remarkably consistent with the integrated water vapor transport(IVT)*** IVT is found associated with the interaction between southwesterly(southerly)of the BoBTC circulation and low-level monsoonal flow in May(midlevel westerly in winter months).The probabilities of extreme precipitation(EP)occurrences over the above regions all increase on *** adjacent regions,EP is significantly correlated with the northward IVT anomalies to the east of BoBTC circulation,which strengthen the water vapor input through the southern *** IVT anomalies are stronger in May,benefited by the deep monsoonal southwesterlies than those in *** distant regions,EP is more closely related to the IVT anomaly extending back from *** moisture from BoB concentrates along a local low-level convergence line over Southeast China,being further facilitated by coexistence of the BoBTC depression and midlevel westerly trough in *** results highlight the interactions between BoBTCs and local weather systems that influence the general precipitation anomalies and occurrence of EP over China,especially over distant regions.

关键词： tropical cyclone Bay of Bengal precipitation anomaly moisture transport

Synthesis of granulated li_(1.33)Mn_(1.67)O_(4) via two antisolvent methods for lithium adsorption from gas-produced water

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Chinese Journal of Chemical Engineering 2024年第5期69卷 34-46页

作者： Jun Qiu Lu-Ri Bao Wei Guo ying Yang Shu-ying Sun National Engineering Research Center for Integrated Utilization of Salt Lake Resource East China University of Science and TechnologyShanghai 200237China

Gas-produced water is an accompanying wastewater in the natural gas extraction process,and it is a potential liquid lithium resource that contains a considerable amount of *** study investigated the feasibility of using manganese-based ion sieves to adsorb and extract lithium from gas-produced *** we focused on the applicability of two different granulation methods,extrusion and droplet,in gas-produced water *** types of H_(1.33)Mn_(1.67)O_(4) particles were prepared by the extrusion method(EHMO)and the droplet method(DHMO).The porosity of DHMO was much higher than that of EHMO,and the adsorption performance of DHMO increased with the decrease of binder *** prepared with a binder concentration of 0.14 g·ml^(-1)exhibited the best adsorption performance in gas-produced water,and the li^(+)adsorption capacity could reach 25.14 mg·g^(-1).In gas-produced water,the adsorption equilibrium of DHMO only took 9 h,and the adsorption process conformed to the Langmuir model and pseudo-second-order kinetic *** pore diffusion model(PDM)could well describe its adsorption ***,DHMO showed a great selectivity to li^(+),and the selectivity order of DHMO in gas-produced water was li^(+)>Ba^(2+)>>Mg^(2+),Ca^(2+),Sr^(2+)>>Na^(+)>>K^(+).After 20 cycles,the li^(+)adsorption capacity was still higher than 17.30 mg·g^(-1),and the rate of manganese dissolution was less than 1%.

关键词： Gas-produced water Granulation li_(1.33)Mn_(1.67)O_(4)

Integrating Shipborne Images with Multichannel Deep Learning for Landslide Detection

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Journal of Earth Science 2024年第1期35卷 296-300页

作者： Pengfei Feng Changdong li shuang Zhang Jie Meng Jingjing Long School of Mechanical Engineering and Electronic Information China University of GeosciencesWuhan 430074China Faculty of Engineering China University of GeosciencesWuhan 430074China Department of Civil Badong National Observation and Research Station of Geohazards China University of GeosciencesWuhan 430074China College of Geology Engineering and Geomatics Changan UniversityXi'an 710054China Department of Geosciences University of OsloOslo 0316Norway

0 *** disasters in recession zones along riverbanks impose significant global social,economic,and ecological *** areas are particularly susceptible to *** inflict significant harm due to fluctuating water levels(Meng et al.,2023;Dai et al.,2021;li et al.,2021).This,in turn,endangers the safety and accessibility of roads and waterways adjacent to rivers,and hydropower station and reservoir security(Yan et al.,2022;Guo et al.,2020;Tang et al.,2017).

关键词： reservoir Landslide Ship

The guest CH_(3)CN molecule triggers solid-state photochromism in a Cu_(2)I_(2)-based MOF for advanced time-dependent encryption and inkless erasable printing

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Chinese Chemical Letters 2024年第3期35卷 532-537页

作者： Meng-Juan Wang Bo li Yong-li Wei Shu-Na Zhao shuang-Quan Zang Henan Key Laboratory of Crystalline Molecular Functional Materials Henan International Joint Laboratory of Tumor Theranostical Cluster MaterialsGreen Catalysis Centerand College of ChemistryZhengzhou UniversityZhengzhou 450001China College of Chemistry and Pharmaceutical Engineering Nanyang Normal UniversityNanyang 473061China

It remains a big challenge to develop solid-state stimuli-responsive materials for time-dependent information encryption and inkless erasable printing with long retention ***,a 2D Cu_(2)I_(2)-based MOF with photoresponsive spiropyran(SP)groups orderly installed on its skeleton is *** structural isomerization from SP to colored merocyanine(MC)form can be triggered by removing the CH_(3)CN ***,the degree of structural isomerization and the retention time can be adjusted by controlling the amount of CH_(3)CN guests,exhibiting dynamic photochromic behavior with multicolor states and tunable retention *** on these advantages,time-dependent information encryption is successfully ***,the long retention time(>72 h)of the MC form under daylight conditions in the CH_(3)CN-removed Cu_(2)I_(2)-based MOF and good repeatability make it promising in various applications,such as temporary calendars,price-cards,billboards,and reusable identity *** work provides a novel design strategy to fabricate multi-functional MOF-based smart materials for challenging applications of time-dependent information encryption and inkless erasable printing.

关键词： Stimuli-responsive materials Spiropyran Solid-state photochromism Time-dependent encryption Inkless erasable printing

Phylogenetic study on Scenedesmacae with the description of a new genus Coccoidesmus ***.(Chlorophyceae,Chlorophyta)and chloroplast genome analyses

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Journal of Oceanology and limnology 2024年第4期42卷 1272-1285页

作者： Qinghua WANG ying HOU Yanhui li ying SHI Guoxiang liU College of Biological Sciences and Technology Taiyuan Normal UniversityJinzhong 030619China Shanxi Vocational University of Engineering Science and Technology Jinzhong 030619China Key Laboratory of Algal Biology Institute of HydrobiologyChinese Academy of SciencesWuhan 430072China

Members of the family Scenedesmaceae are some of the most common algal taxa in inland ecosystems,and they are widely distributed in freshwaters,aerial,and sub-aerial *** the continuous updating of methods,the classic morphological taxonomy of this family needs to be *** recent years,many genera of Scenedesmaceae have been established via the use of molecular *** phylogenetic relationships within Scenedesmaceae were analyzed using different molecular markers and morphological data,and the new freshwater genus Coccoidesmus Wang,Hou et liu *** *** new species in this genus were also *** analysis based on tufA genes revealed that the new genus formed an independent clade closely related to ***,these two genera are characterized by significant morphological differences in colony arrangement and cell *** chloroplast genome of the type species was assembled and annotated,and analyses of genome structure and sequences were *** genome data could help clarify the phylogenetic relationships within this family.

关键词： phylogenetic Scenedesmaceae Coccoidesmus morphology chloroplast genome