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Inner fission barriers of uranium isotopes in the deformed relativistic Hartree-Bogoliubov theory in continuum

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Chinese Physics C 2024年第10期48卷 214-221页

作者： Wei zhang Jin-Ke Huang Ting-Ting Sun Jing Peng shuang-quan zhang School of Physics Zhengzhou UniversityZhengzhou 450001China Department of Physics Beijing Normal UniversityBeijing 100875China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China

The inner fission barriers of the even-even uranium isotopes from the proton to the neutron drip line are examined using the deformed relativistic Hartree-Bogoliubov theory in continuum.A periodic-like evolution for the ground state shapes is shown with respect to the neutron number,i.e.,spherical shapes at shell closures 126,184,258,and prolate dominated shapes between *** to the shape evolution,the inner fission barriers also exhibit a periodic-like behavior:peaks at the shell closures and valleys in the *** triaxial effect on the inner fission barrier is evaluated using triaxial relativistic mean field calculations combined with a simple BCS method for *** the triaxial correction is included,the inner barrier heights show good consistency with available empirical ***,the evolution from the proton to the neutron drip line aligns with results from the multi-dimensionally constrained relativistic mean field theory.A flat valley in the fission barrier height is predicted around the neutron-rich nucleus U which may play a role of fission recycling in astrophysical r-process nucleosynthesis.

关键词： inner fission barrier potential energy curve triaxiality deformed relativistic Hartree-Bogoliubov theory in continuum

Beyond-mean-field dynamical correlations for nuclear mass table in deformed relativistic Hartree-Bogoliubov theory in continuum

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Chinese Physics C 2022年第6期46卷 154-163页

作者： Wei Sun Kai-Yuan zhang Cong Pan Xiao-Hua Fan shuang-quan zhang Zhi-Pan Li School of Physical Science and Technology Southwest UniversityChongqing 400715China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China

We extend the deformed relativistic Hartree-Bogoliubov theory in continuum(DRHBc)to go beyondmean-field framework by performing a two-dimensional collective *** influences of dynamical correlations on the ground-state properties are examined in different mass regions,picking Se,Nd,and Th isotopic chains as *** is found that the dynamical correlation energies(DCEs)and the rotational correction energies E_(rot) in the cranking approximation have an almost equivalent effect on the description of binding energies for most deformed nuclei,and the DCEs can provide a significant improvement for the(near)spherical nuclei close to the neutron shells and thus reduce the rms deviations of S_(2n) by≈17%.Furthermore,it is found that the DCEs are quite sensitive to the pairing correlations;taking ^(148)Nd as an example,a 10%enhancement of pairing strength can raise the DCE by≈37%.

关键词： mass table covariant density functional theory dynamical correlation energy collective Hamiltonian

Performance of digital data acquisition system in gamma-ray spectroscopy

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Nuclear Science and Techniques 2021年第8期32卷 12-22页

作者： Di-Wen Luo Hong-Yi Wu Zhi-Huan Li Chuan Xu Hui Hua Xiang-Qing Li Xiang Wang shuang-quan zhang Zhi-Qiang Chen Chen-Guang Wu Yu Jin Jie Lin State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China

A newly developed digital data acquisition system,which is based on the digital pulse processor Pixie-16 modules by XIA LLC,was tested with the c-ray detector array of the China Institute of Atomic Energy using the cray source and in-beam c-rays.A comparison between this digital data acquisition system and the conventional analog data acquisition system was *** a low count rate,both systems exhibit good and comparable energy *** a high count rate above 8.8 k/s,while the energy resolution obtained by the analog system deteriorates significantly,the energy resolution obtained by the digital system is nearly ***,experimental data with higher statistics can be collected by the digital *** advantage of this digital system over the conventional analog system can be ascribed to its excellent capability of handling pile-up pulses at higher count rates,and the fact that it has nearly no dead time in data transmission and conversion.

关键词： Digital data acquisition system Gamma spectroscopy Energy resolution

Examination of machine learning for assessing physical effects:Learning the relativistic continuum mass table with kernel ridge regression

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Chinese Physics C 2023年第7期47卷 138-150页

作者：杜晓凯郭鹏吴鑫辉张双全 State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China

The kernel ridge regression(KRR)method and its extension with odd-even effects(KRRoe)are used to learn the nuclear mass table obtained by the relativistic continuum Hartree-Bogoliubov *** respect to the binding energies of 9035 nuclei,the KRR method achieves a root-mean-square deviation of 0.96 MeV,and the KRRoe method remarkably reduces the deviation to 0.17 *** investigating the shell effects,one-nucleon and twonucleon separation energies,odd-even mass differences,and empirical proton-neutron interactions extracted from the learned binding energies,the ability of the machine learning tool to grasp the known physics is *** is found that the shell effects,evolutions of nucleon separation energies,and empirical proton-neutron interactions are well reproduced by both the KRR and KRRoe methods,although the odd-even mass differences can only be reproduced by the KRRoe method.

关键词： machine learning kernel ridge regression relativistic continuum Hartree-Bogoliubov theory nuclear mass table

Bending Stiffness of Concrete-Filled Steel Tube and Its Influence on Concrete Placement Timing of Composite Beam-String Structure

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Structural Durability & Health Monitoring 2025年第1期19卷 55-75页

作者： Zhenyu zhang quan Jin Haitao zhang Zhao Liu Yuyang Wu Longfei zhang Renzhang Yan CCCC Third Highway Engineering Co. Ltd.Beijing101300China School of Civil Engineering Chongqing Jiaotong UniversityChongqing400074China

When the upper chord beam of the beam-string structure(BSS)is made of concrete-filled steel tube(CFST),its overall stiffness will change greatly with the construction of concrete placement,which will have an impact on the design of the tensioning plans and selection of control measures for the *** order to accurately obtain the bending stiffness of CFST beam and clarify its impact on the mechanical properties of composite BSS during construction,the influence of some factors such as height-width ratio,wall thickness of steel tube,elasticity modulus of concrete,and friction coefficient on the bending stiffness are analyzed parametrically by the numerical simulation technology based on an actual *** calculation formula of the equivalent bending stiffness of CFST is also established through mathematical statistical ***,the equivalent bending stiffness is introduced into the construction and use stages of the composite BSS,respectively,and the mechanical properties such as prestress-tensioning control value,structural deformation,and internal force of key members are comparatively analyzed when adopting two different construction ***,the optimal construction plan of concrete placement first and then prestress-tensioning is proposed.

关键词： Concrete panels freeze-thaw damage compression-shear crack tension-shear crack

重组人sBLyS表达纯化条件的优化、理化特征及生物功能研究

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生物工程学报 2002年第3期18卷 318-322页

作者：闫晓梅张双全张大鹏刘美艳刘平南京师范大学生命科学学院生物化学与分子生物学研究室南京210097

构建了原核表达质粒pET 30a(+) sBLyS ,转化大肠杆菌BL2 1(λDE3) ,IPTG诱导表达的重组蛋白以可溶部分和包涵体两种形式存在 ,为了提高可溶部分重组蛋白的比例 ,确定 16℃为诱导表达的温度 ,最佳表达时间为 12h。在此条件下大规模诱导... 详细信息

构建了原核表达质粒pET 30a(+) sBLyS ,转化大肠杆菌BL2 1(λDE3) ,IPTG诱导表达的重组蛋白以可溶部分和包涵体两种形式存在 ,为了提高可溶部分重组蛋白的比例 ,确定 16℃为诱导表达的温度 ,最佳表达时间为 12h。在此条件下大规模诱导表达 ,经Ni2 +亲和层析获得重组人sBLyS。重组蛋白的等电点约为 7 1～ 7 3,活性状态时是非共价连接的同源三聚体。MTT法测重组人sBLyS对B淋巴细胞的增殖作用结果表明 ,B细胞经抗IgM原血清活化后 ,它的增殖程度在一定的重组人sBLyS浓度范围内随其浓度的增加而提高 ,sBLyS刺激时间对B细胞增长也有显著影响 ,sBLyS以 2 μg mL刺激

关键词：重组人sBLyS 表达纯化条件优化理化特征生物功能

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting Li Wei zhang Jian Wu Hui Hong Wei quan Xinyu Qiao Chun Cui Chenmeng Qiao Weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

Unraveling the mechanism of action of Shangxia Liangji formula for treating insomnia:a metabolomics and network pharmacology approach

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Traditional Medicine Research 2025年第2期10卷 16-29页

作者： Xia-Jie quan Hao Liang Yong-Hong Tang Li Jiang Xiong-Ying Ji Feng-Ying zhang Ping zhang Bo Ouyang Department of Information The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Neurology The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Gastroscopy The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Traditional Chinese Medicine The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China

Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of ***,the specific mechanism of action of SXLJF remains ***:The mouse model of insomnia was established by intraperitoneal injection of ***-two mice were randomly divided into a negative control group,model group,SXLJF group(18.72 g/kg/day),and positive control group(diazepam,2 mg/kg)and treated with the corresponding drugs for 7 consecutive *** open field test and pentobarbital-induced sleeping test were ***-MS-based untargeted metabolomics and network pharmacology were applied to explore the potential targets of SXLJF for treating ***,key targets were validated using ***:Behavioral tests demonstrated that SXLJF reduced the total distance,average velocity,central distance,and sleep latency,and prolonged sleep *** and network pharmacology revealed potential targets,signaling pathways,metabolic pathways,and metabolites associated with the anti-insomnia effects of ***,tyrosine hydroxylase(TH)and tyrosine metabolism emerged as crucial metabolic pathways and targets,***-qPCR results supported the role of TH in the mechanism of SXLJF in treating ***:In conclusion,TH and tyrosine metabolism may represent significant targets and pathways for SXLJF in treating insomnia.

关键词： Shangxia Liangji formula insomnia metabolomics network pharmacology tyrosine hydroxylase tyrosine metabolism

创新体制机制,探索机电类应用型本科人才培养的研究

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邢台职业技术学院学报 2016年第4期33卷 9-11,22页

作者：赵双全张兆隆张能云张振山河北机电职业技术学院河北邢台054000

立足于本科院校、高等职业院校和行业协会三方共同培养应用型本科人才培养的研究与实践,分析了当前应用型本科人才培养过程中存在的问题,提出了通过创新体制机制,构建产教融合、校企合作的人才培养模式和对策。

关键词：创新体制机制应用型本科人才培养对策