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Comparisons of Fly Ash and Deposition Between Air and Oxy-Fuel Combustion in Bench-Scale Fluidized Bed with Limestone Addition

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Journal of Harbin Institute of Technology(New Series) 2015年第5期22卷 78-84页

作者： Zhimin Zheng Hui Wang Yongjun guo Li Yang shuai guo Shaohua Wu School of Energy Science and Engineering Harbin Institute of Technology

In Oxy-fuel circulating fluidized bed,the residual Ca O particles may react with high concentration of CO2 in flue gas to form bonded deposit on heat transfer surfaces in backpass when limestone is used as a sorbent to capture *** this paper,experiments were designed on ash deposition in a bench-scale fluidized bed under oxy-fuel and air atmosphere. A novel ash deposit sampling probe was used to simulate the tubes of tail *** chemical composition of fly ash and ash deposit from both air-firing and oxy-fuel firing cases were analyzed by Inductively Coupled Plasma-Atomic Emission Spectrometry( ICP-AES) and Scanning Electron Microscopy( SEM),respectively. The degrees of carbonation reaction of ash deposits were measured by Thermo Gravimetric Analysis. The results showed that there are distinct differences in fly ash deposition rate between oxy-fuel and air firing cases,and oxy-fuel combustion with limestone addition can affect chemical composition of fly ash and ash deposit,especially for elements of Ca,Na,K,and S. However,the carbonation reaction degree of ash deposits is found weak,which is due to the relatively low Ca O content in ash deposit or not long enough of the sampling time.

关键词： carbonation ash deposit fly ash oxy-fuel CFB

Long noncoding RNA NALT1-induced gastric cancer invasion and metastasis via NOTCH signaling pathway

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World Journal of Gastroenterology 2019年第44期25卷 6508-6526页

作者： Hai-Yan Piao shuai guo Yue Wang Jun Zhang Medical Oncology Department of Gastrointestinal Cancer Liaoning Province Cancer Hospital&Institute(Cancer Hospital of China Medical University)Shenyang 110042Liaoning ProvinceChina Gastric Cancer Department Liaoning Province Cancer Hospital&Institute(Cancer Hospital of China Medical University)Shenyang 110042Liaoning ProvinceChina

BACKGROUNDLong noncoding RNAs (lncRNAs) are aberrant and play critical roles in gastriccancer (GC) progression and metastasis. Searching for coexpressed lncRNAclusters or representative biomarkers related to malignant phenotypes of GC mayhelp to elucidate the mechanism of tumor development and predict the prognosisof *** investigate the prognostic value of NOTCH1 associated with lncRNA in T cellacute lymphoblastic leukemia 1 (NALT1) in GC and the mechanism of itsinvolvement in GC invasion and *** sequencing and corresponding clinical data were downloaded from TheCancer Genome Atlas database. The significance module was studied byweighted gene coexpression network analysis. A total of 336 clinical sampleswere included in the study. Gene silencing, reverse transcription polymerasechain reaction, western blotting, scrape motility assay, and Transwell migrationassay were used to assess the function of *** the transcriptome level, 3339 differentially expressed lncRNAs were *** gene coexpression network analysis was used to obtain 15 lncRNAclusters and observe their coexpression. Pearson’s correlation showed that blue module was correlated with tumor grade and survival. NALT1 was the hublncRNAof blue module and was an independent risk factor for GC ***1 was overexpressed in GC and its expression was closely related toinvasion and metastasis. The mechanism may involve NALT1 regulation ofNOTCH1, which is associated with lncRNA in T cell acute lymphoblasticleukemia, through cis regulation, thereby affecting the expression of the NOTCHsignaling ***1 is overexpressed and promotes invasion and metastasis of GC. Themechanism may be related to regulation of NOTCH1 by NALT1 and its effect onNOTCH signaling pathway expression.

关键词： Gastric cancer Weighted gene coexpression network analysis NALT1 NOTCH1 Cancer survival

Laser fragmentation in liquid synthesis of novel palladium-sulfur compound nanoparticles as efficient electrocatalysts for hydrogen evolution reaction

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Chinese Physics B 2022年第7期31卷 34-40页

作者： guo-shuai Fu Hong-Zhi Gao guo-Wei Yang Peng Yu Pu Liu State Key Laboratory of Optoelectronic Materials and Technologies Nanotechnology Research CenterSchool of Materials Science&EngineeringSun Yat-sen UniversityGuangzhou 510275China

One promising way to tune the physicochemical properties of materials and optimize their performance in various potential applications is to engineer material structures at the atomic *** is well known,the performance of Pd-based catalysts has long been constrained by surface contamination and their single ***,we employed an unadulterated top-down synthesis method,known as laser fragmentation in liquid(LFL),to modify pristine Pd PS crystals and obtained a kind of metastable palladium-sulfur compound nanoparticles(LFL-Pd S NPs)as a highly efficient electrocatalyst for hydrogen evolution reaction(HER).Laser fragmentation of the layered Pd PS crystal led to a structural reorganization at the atomic level and resulted in the formation of uniform metastable LFL-Pd S ***,the LFL-Pd S NPs show excellent electrocatalytic HER performance and stability in acidic media,with an overpotential of-66 m V at 10 m A·cm^(-2),the Tafel slope of 42 m V·dec^(-1).The combined catalytic performances of our LFL-Pd S NPs are comparable to the Pt/C catalyst for *** work provides a top-down synthesis strategy as a promising approach to design highly active metastable metal composite electrocatalysts for sustainable energy applications.

关键词： Pd-based electrocatalyst hydrogen evolution reaction laser fragmentation in liquid nanoparticles

基于IKKβ/NF-κB/COX-2信号通路探讨桃红四物汤加味对糖尿病肾病大鼠炎性因子及肾脏纤维化的干预作用

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中药药理与临床 2024年第6期40卷 11-17页

作者：白璐陈永哲王倩李敏沈士朋郭帅杨帆刘茂东河北医科大学第三医院肾内科石家庄050051 河北省糖尿病肾脏疾病重点实验室石家庄050051 河北中医药大学石家庄050091

目的:探讨桃红四物汤加味对糖尿病肾病大鼠炎性因子及肾脏IKKβ/NF-κB/COX-2信号通路表达及纤维化的影响。方法:10只大鼠随机选为正常对照组,其余大鼠采用高脂饲料联合链脲佐菌素35 mg/kg腹腔注射建立糖尿病肾病模型,模型制备成功后分... 详细信息

目的:探讨桃红四物汤加味对糖尿病肾病大鼠炎性因子及肾脏IKKβ/NF-κB/COX-2信号通路表达及纤维化的影响。方法:10只大鼠随机选为正常对照组,其余大鼠采用高脂饲料联合链脲佐菌素35 mg/kg腹腔注射建立糖尿病肾病模型,模型制备成功后分为模型对照组、厄贝沙坦0.0135 g/kg组、桃红四物汤加味3.24、6.48、12.96 g/kg组。各组大鼠灌胃给予相应药物干预16 w,于16 w末检测大鼠空腹血糖(FBG)、24 h尿蛋白定量(24 h UTP)、肌酐(Scr)、尿素氮(BUN)含量;ELISA法检测血浆中炎性因子白介素-1β(IL-1β)、IL-6、TNF-α含量;HE、Masson染色观察肾脏病理学改变;Real-time PCR法检测肾组织IκαB激酶β(Ikkb)、核转录因子-κB p65(Nfkb p65)、环氧合酶-2(Cox2)、转化生长因子-β1(Tgfb1)、IV型胶原(Col-IV)、α-平滑肌肌动蛋白(Asma)mRNA的表达;免疫组化法(IHC)检测肾组织TGF-β1、COL-IV、α-SMA、NF-κB p65蛋白的表达;Western blotting法检测肾组织IKKβ、NF-κB p65、COX-2蛋白的表达。结果:与正常对照组比较,模型对照组大鼠FBG、24 h UTP、BUN含量明显升高(P<0.05),光镜观察发现肾小球肥大,系膜基质增加,基底膜增厚,肾小囊囊腔变窄,肾小管部分空泡变性,血浆中IL-1β、IL-6、TNF-α含量明显增加(P<0.05),肾组织纤维化相关蛋白Tgfb1、Col-IV、Asma mRNA及蛋白表达均明显上调(P<0.05),肾组织Ikkb、Nfkb p65、Cox2 mRNA及蛋白表达明显上调(P<0.05);与模型对照组比较,桃红四物汤加味6.48、12.96 g/kg组DN大鼠24 h UTP、BUN含量降低,IL-1β、IL-6、TNF-α含量降低(P<0.05),病理损伤程度减轻,同时IKKβ/NF-κB/COX-2信号通路及纤维化相关因子mRNA和蛋白表达下调(P<0.05)。结论:桃红四物汤加味可能通过抑制DN大鼠肾脏IKKβ/NF-κB/COX-2信号通路表达,减轻炎症反应及纤维化进展,减轻肾脏病理损伤,具有明确的肾保护作用。

关键词：桃红四物汤加味糖尿病肾病炎性因子纤维化 IκB激酶β/核因子κB/环氧酶2信号通路

Evolution of gas kick and overflow in wellbore and formation pressure inversion method under the condition of failure in well shut-in during a blowout

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Petroleum Science 2022年第2期19卷 678-687页

作者： guo-shuai Ju Tie Yan Xiao-Feng Sun Jing-Yu Qu Qiao-Bo Hu College of Petroleum Engineering Northeast Petroleum UniversityDaqing163318HeilongjiangPeople's Republic of China

With ongoing development of oil exploration and techniques,there is a significant need for improved well control strategies and formation pressure prediction *** this paper,a gas-liquid transient drift flow model was established according to the gas-liquid two-phase flow characteristics during the gas kick.A Roe scheme was used for numerical calculation based on the finite volume *** changes of bottom-hole pressure,casing pressure,the development law of cross-sectional gas holdup,and gas velocity,along with the vertical well depth,were analyzed through simulation *** time-series characteristics of mud pit gain were obtained by adjusting the formation *** complex nonlinear mapping relationship between the formation parameters and the mud pit gain was *** long short-term memory network(LSTM)of deep learning was used to obtain a formation pressure inversion when the blowout is out of control and the well cannot be *** data from a well were used to verify the gas-liquid two-phase transient drift flow model based on the finite volume method,demonstrating that this method is reliable,with greatly improved prediction *** approach provides theoretical support for the early monitoring of gas kick during drilling,and for well-killing design and construction after uncontrolled blowout.

关键词： Gas kick Formation pressure Multiphase flow Computational model Long short-term memory

Investigation of Induced Unbalance Magnitude on Dynamic Characteristics of High-speed Turbocharger with Floating Ring Bearings

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Chinese Journal of Mechanical Engineering 2018年第5期31卷 99-109页

作者： Guang-Fu Bin Yuan Huang shuai-Ping guo Xue-Jun Li Gang Wang Health Maintenance for Mechanical Equipment Key Lab of Hunan Province Hunan University of Science and Technology Xiangtan 411201 China Department of Mechanical and Aerospace Engineering The University of Alabama in Huntsville AL 35899 USA

Due to operational wear and uneven carbon absorption in compressor and turbine wheels, the unbalance(me) vibration is induced and could lead to sub?synchronous vibration accidents for high?speed turbocharger(TC). There are very few research works that focus on the magnitude e ects on such induced unbalance vibration. In this paper, a finite element model(FEM) is developed to characterize a realistic automotive TC rotor with floating ring bearings(FRBs). The nonlinear dynamic responses of the TC rotor system with di erent levels of induced unbalance magni?tude in compressor and turbine wheels are calculated. From the results of waterfall and response spectral intensity plots, the bifurcation and instability phenomena depend on unbalance magnitude during the startup of TC. The sub?synchronous component 0.12× caused rotor unstable is the dominant frequency for small induced unbalance. The nonlinear e ects of induced unbalance in the turbine wheel is obvious stronger than the compressor wheel. As the unbalance magnitude increases from 0.05 gbration 1·mm to 0.2 g·mm, the vibration component changes from mainly 0.12× to synchronous vi×. When unbalance increases continuously, the rotor vibration response amplitude is rapidly growing and the 1× caused by the large unbalance excitation becomes the dominant frequency. A suitable un?balance magnitude of turbine wheel and compressor wheel for the high?speed TC rotor with FRBs is proposed: the value of induced un?balance magnitude should be kept around 0.2 g·mm.

关键词： High?speed TC with FRBs Induced unbalance magnitude Nonlinear dynamic response Sub?synchronous vibration Stability

Diffraction separation and imaging based on double sparse transforms

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Petroleum Science 2022年第2期19卷 534-542页

作者： Xue Chen Jing-Jie Cao He-Long Yang Shao-Jian Shi Yong-shuai guo Hebei Key Laboratory of Strategic Critical Mineral Resources Hebei GEO UniversityShijiazhuangHebei 050031China Hebei Nautral Resources Archives ShijiazhuangHebei 050037China The Third Hydrogeological Engineering Geological Brigade HengshuiHebei 053000China

Reflection imaging results generally reveal large-scale continuous geological information,and it is difficult to identify small-scale geological bodies such as breakpoints,pinch points,small fault blocks,caves,and fractures,*** imaging is an important method to identify small-scale geological bodies and it has higher resolution than reflection *** the common-offset domain,reflections are mostly expressed as smooth linear events,whereas diffractions are characterized by hyperbolic *** paper proposes a diffraction extraction method based on double sparse *** linear events can be sparsely expressed by the high-resolution linear Radon transform,and the curved events can be sparsely expressed by the Curvelet transform.A sparse inversion model is built and the alternating direction method is used to solve the inversion *** data and field data experimental results proved that the diffractions extraction method based on double sparse transforms can effectively improve the imaging quality of faults and other small-scale geological bodies.

关键词： Diffraction separation Common-offset domain Diffraction imaging High-resolution linear Radon transform Curvelet transform Sparse inversion

Three-primary-color molecular cocrystals showing white-light luminescence,tunable optical waveguide and ultrahigh polarized emission

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Science China Chemistry 2022年第2期65卷 408-417页

作者： Shuzhen Li Yan Hao shuai guo Chunjie Ding Yujuan Ma Ruibin Liu Dongpeng Yan Beijing Key Laboratory of Energy Conversion and Storage Materials College of ChemistryBeijing Normal UniversityBeijing 100875China Beijing Key Lab of Nanophotonics and Ultrafine Optoelectronic Systems School of PhysicsBeijing Institute of TechnologyBeijing 100081China College of Chemistry and Molecular Engineering Zhengzhou UniversityZhengzhou 450001China

Three-primary-color luminescent materials are highly desirable to construct white-light emitting resource,multi-color optical displays,and tunable photonic ***,the efficient strategy to establish the three-primary-color systems with unique photofunctionalities is still rather limited,particularly for molecular ***,we developed a molecular cocrystal route to obtain three-primary-color emissive materials by tuning different donor-acceptor units based on the same chromophore(4,4′-bis(2,5-dimethylstyryl)biphenyl,Bdb).The warm and cold white-light together with multi-color emission in most of visible region can be highly adjusted by rationally tuning different mixture components of three-primary-color cocrystals through an energy transfer ***,the blue/green/red emitters endow Bdb molecular cocrystals novel colortunable photonic properties(such as one-dimensional(1D)/2D optical waveguide,polarized fluorescence,up-conversion luminescence,and amplified spontaneous emission),benefitting from their well-defined micro/nanostructures and high ***,the high luminescence quantum yield(82.49%)and polarized anisotropy(0.723)outperform most of state-ofthe-art molecular crystalline ***,this work supplies an effective way to fabricate new types of three-primarycolor phosphors through luminescent cocrystals,which have promising applications in the fields of full-color displays,whitelight irradiation,low-dimensional optical polarization,and micro/nanophotonics.

关键词： three-primary-color emission molecular crystal white light optical waveguide polarized luminescence

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新时代高校师生关系的伦理分析及建构

山西大同大学学报（社会科学版） 2024年第3期38卷 43-46页

作者：朱江鸿刘国帅张健太原科技大学车辆与交通工程学院山西太原030024

师生关系是教育活动中最核心的关系,高质量的师生关系是实施高水平教育活动的必要保障。将高校师生关系置于新时代背景之下,审视当前师生关系存续中存在的伦理问题,探讨良性师生关系应有的伦理精神,从优化教师职业道德规范、提升学生思... 详细信息

师生关系是教育活动中最核心的关系,高质量的师生关系是实施高水平教育活动的必要保障。将高校师生关系置于新时代背景之下,审视当前师生关系存续中存在的伦理问题,探讨良性师生关系应有的伦理精神,从优化教师职业道德规范、提升学生思想道德修养、加强校园伦理环境建设、营造尊师爱生社会氛围等方面着手构建“亲清”师生关系的伦理策略,为高校师生确立立德修身、遵纪守法的规范性要求,也为优化并发挥师生教育共同体的价值功能、践履立德树人的职责使命注入深厚的伦理意蕴。

关键词：新时代亲清师生关系伦理关系