检索结果-南通市图书馆

Eosinophilia complicated with venous thromboembolism:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第6期10卷 1952-1960页

作者： Wei-Qiang Su yan-Zhong Fu shu-yan liu Meng-Jie Cao Ya-Bin Xue Fei-Fei Suo Wen-Chao liu Department of Vascular Surgery The Second People’s Hospital of Jiaozuo CityJiaozuo 454000Henan ProvinceChina Department of Endocrine The Second People’s Hospital of Jiaozuo CityJiaozuo 454000Henan ProvinceChina Department of Neurology The Second Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Clinical Laboratory The Second People’s Hospital of Jiaozuo CityJiaozuo 454000Henan ProvinceChina

BACKGROUND Eosinophilia is an increase of more than 0.5×109/L in the number of eosinophils;it is a systemic condition with an unknown etiology and is often accompanied by multiple impaired organ *** clinical manifestations of the disease are highly variable and diverse,rendering identification of the diagnosis challenging;hence,diagnosis and treatment are often *** few reports of this disease exist globally,especially with rare manifestations of cerebral venous sinus thrombosis and *** SUMMARY A 32-year-old woman with eosinophilia presented to the hospital with bilateral lower-limb edema as the first clinical manifestation,followed by an extensive maculopapular rash throughout the *** subsequently developed cerebral venous sinus thrombosis along with bilateral lower-limb deep vein *** weeks earlier,she had received a single course of antibiotics from a local hospital for a low-grade fever and sore *** various treatments were administered for anticoagulation,maintaining blood circulation,and relieving blood stasis,the lower extremity edema improved significantly;however,the patient’s eosinophil count gradually *** experienced cerebral venous sinus thrombosis,cerebral hemorrhage,and deep vein thrombosis of the lower limbs before being declared brain *** this case report,we have elaborated the diagnosis and management of deep vein thrombosis manifested as eosinophilia,thrombocytopenia,and elevated D-dimer *** Because proper diagnosis is challenging,clinical vigilance is required for patients with eosinophilia,as it can lead to thrombus formation.

关键词： Eosinophilia Venous thromboembolism Diagnosis Management Venous thrombosis Case report

Copper oxide-modified highly reversible Zn powder anode for aqueous Zn metal batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第10期43卷 5005-5016页

作者： Guan-Qun liu Biao Fu Zhe-Xuan liu Lan-yan Li shu-Quan Liang Guo-Zhao Fang School of Materials Science and Engineering Key Laboratory of Electronic Packaging and Advanced Functional Materials of Hunan ProvinceCentral South University School of Science Hunan University of Technology and Business National Energy Metal Resources and New Materials Key Laboratory Central South University

With the advantages of mature preparation technology,structural adjustability and suitability for large-scale application,Zn powder anode is considered to be an ideal electrode for realizing low-cost,high-energy-density aqueous Zn metal ***,the high specific surface of Zn powders leads to severe side reactions such as hydrogen evolution and corrosion,thus limiting their widespread use Here,this work develops a novel CuO@Zn powder anode with a synergy effect of surface wrapping and *** powders are uniformly wrapped by small CuO particles due to the strong adsorption between Zn and *** wrapped CuO particles build a good conductive framework to inhibit the structural collapse of the Zn powder caused by corrosion and non-uniform ***,CuO can also be used as a seed to guide the uniform deposition of Zn ions through its strong binding energy with *** a result,the Cu O@Zn anode can maintain a long cyclic life of 900 h at current density of 1 mA·cm-2and capacity of 1 mAh·cm-2,as well as contribute to an excellent capacity retention of 92%after 800cycles for CuO@Zn||NH4V4O10full *** at high current density of 5 A·g-1,the full cell exhibits a specific capacity of more than 200 mAh·g-1after 800 cycles,with a good capacity retention of 89%.This work provides a new idea for developing high-performance Zn powder-based anodes.

关键词： Aqueous Zn metal batteries Copper oxide Surface wrapping Zn anode Zn powder

Experimental investigation for temperature and emissivity by flame emission spectrum in a cavity of rocket based combined cycle combustor chamber

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第9期39卷 114-122页

作者： Weiguang Cai shu Zheng yan Wang Bing liu Shaohua Zhu Li Zhao Qiang Lu National Engineering Research Center of New Energy Power Generation North China Electric Power UniversityBeijing 102206China Science and Technology on Combustion Internal Flow and Thermal-structure LaboratoryNorthwestern Polytechnical UniversityXi'an 710072China

Flame temperature and spectral emissivity were the important parameters characterizing the sufficient degree of fuel combustion and the particle radiative characteristics in the Rocket Based Combined Cycle(RBCC)*** investigate the combustion characteristics of the complex supersonic flame in the RBCC combustor,a new radiation thermometry combined with Levenberg-Marquardt(LM)algorithm and the least squares method was proposed to measure the temperature,emissivity and spectral radiative properties based on the flame emission ***-situ measurements of the flame temperature,emissivity and spectral radiative properties were carried out in the RBCC direct-connected test bench with laser-induced plasma combustion enhancement(LIPCE)and without *** flame average temperatures at fuel global equivalence ratio(a)of 1.0b and 0.6 with LIPCE were 4.51%and 2.08%higher than those without *** flame combustion oscillation of kerosene tended to be stable in the recirculation zone of cavity with the thermal and chemical effects of laser induced *** differences of flame temperature at a=1.0b and 0.6 were 503 K and 523 K with LIPCE,which were 20.07%and42.64%lower than those without *** flame emissivity with methane assisted ignition was 80.46%lower than that without methane assisted ignition,due to the carbon-hydrogen ratio of kerosene was higher than that of *** spectral emissivities at 600 nm with LIPCE were 1.25%,22.2%,and 4.22%lower than those without LIPCE at a=1.0a(with methane assisted ignition),1.0b(without methane assisted ignition)and *** effect of concentration in the emissivity was removed by normalization to analyze the flame radiative properties in the RBCC combustor *** maximum differences of flame normalized emissivity were 50.91%without LIPCE and 27.53%with *** flame radiative properties were stabilized under the thermal and chemical effects of laser induced plasma at a=0.6.

关键词： Rocket-based combined-cycle Supersonic combustion Flame temperature measurement Emissivity Laser induced plasma combustion enhancement

维普期刊数据库

The Fate of Mitochondria in Ibex-hirus Reconstructed Early Embryos

在线全文

学校读者我要写书评

暂无评论

Acta Biochimica et Biophysica Sinica 2004年第5期36卷 371-374页

作者： yan JIANG, shu-Zhen liu, yan-Ling ZHANG, Man-Xi JIANG, Qing-Yuan SUN, and Da-Yuan CHEN* State Key Laboratory of Reproductive Biology, Institute of Zoology, the Chinese Academy of Sciences, Beijing 100080, China State Key Laboratory of Reproductive Biology Institute of Zoology the Chinese Academy of Sciences Beijing 100080 China

Inter-species nuclear transfer could be used to preserve North Goat (Capra ibex), an endan- gered species. We established the culture conditions for ibex-hirus reconstructed embryos and optimized the method for DNA extractions of a single cell and early cloned embryo. By using mitochondria-specific probes of ibex and hirus respectively we found that mitochondria of donor cells can co-exist with recipients in 1-cell and 2-cell stages of the reconstructed embryos but not in the following developmental stages.

关键词： Capra ibex cloned embryos nuclear transfer mitochondria PCR

Coupling Co2P nanoparticles onto N,P-doped biomass-derived carbon as efficient electrocatalysts for flexible Zn–air batteries

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第10期43卷 4982-4991页

作者： shu-Qi Li Kang Sun yan-yan liu shu-Ling liu Jing-Jing Zhou Wen-Bo Zhang Yi-Hang Lu Xiang-Meng Chen Xiao-Peng Wang Bao-Jun Li Jian-Chun Jiang College of Science Henan Agricultural University Department of Chemistry Tsinghua University College of Chemistry Zhengzhou University Institute of Chemical Industry of Forest Products National Engineering Lab for Biomass Chemical UtilizationKey and Open Lab on Forest Chemical EngineeringChinese Academy of ForestryState Forestry Administration

Catalysts for oxygen conversion play an important role in energy storage and conversion technologies such as metal-air *** highly active stable,and low-cost catalysts is critical for further implementation of the above ***,an efficien oxygen electrocatalyst with Co2P nanoparticles （NPs）coupling onto N,P-doped porous carbon nanosheets（Co2P@NPAC） derived from cotton stalk is successfully designed and prepared via activation,hydrothermal treatment,and pyrolysis *** excellent properties of electrical conductivity,mass transfer,and synergistic integration between Co2P and N,P-doped carbon endow Co2P@NPAC composite with superior oxygen reduction reaction/oxygen evolution reaction （ORR/OER） ***2P@NPAC catalyst achieves ORR activity with half-wave potential of 0.85 V and high OER activity with overpotential of 261 mV at 10 mA·*** flexible Zn-air batteries （ZABs） based on Co2P@NPAC catalyst revea outstanding performances with a high open-circuit voltage（1.38 V）,a peak power density of (75 mW·cm-2),and a low charge-discharge voltage gap （0.74 V,～200 cycles）The flexible ZABs express the stable discharge-charge voltage gap at various bending *** work provides interesting inspiration for the ingenious design of efficien carbon electrocatalysts from biomass with potential application of energy storage and conversion devices.

关键词： Cotton stalk Flexible Zn–air batteries N,P-doped activated carbon Oxygen reduction reaction

Two different autorefractors for vision screening in children and adolescents

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第2期17卷 331-338页

作者： Xiao-Jun Chen Lin-Jie liu Bing Sun Dan-Dan Jiang shu-shu Zuo yan-Hui Wang Chun-Hua Zhang yan-yan Chen School of Optometry and Ophthalmology Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina

AIM:To compare the consistency of two autorefractors(Tianle RM-9000 and Topcon KR-800)for school-age myopia children,and to provide a basis for largescale data analysis and ***:The refractive error in 909 subjects(age 4–18y)were measured using both autorefractors without *** data were analyzed using Fourier decomposition and the correlation coefficients,intraclass correlation coefficients(ICC),and Bland-Altman limits of agreement(LoA)for each parameter were ***:There was a strong correlation between the spherical equivalent(SE),sphere diopter(DS),and cylinder diopter(DC)readings of the Tianle RM-9000 and those of the Topcon KR-800,with correlation coefficient values of 0.98,0.98 and 0.83 and ICC values of 0.99,0.99 and 0.93,***,the correlation coefficients and ICC values of J0 and J45 were unreliable(R=-0.004,-0.034;both ICC<0.10).Bland-Altman analysis revealed that SE,DS,and DC measured by the Tianle RM-9000 were significantly biased toward myopia compared with the Topcon KR-800,and the mean differences were-0.072,-0.026,-0.091 D,respectively(all P<0.01).The minimum absolute value of the difference within the 95%LoA for SE,DS,and DC was 0.63 D,0.50 D,0.62 D,respectively;all these values were in the clinically acceptable *** J0 and J45,the mean differences were close to zero(P=0.43,0.84);however,the 95%LoA were relatively wide(J0 SD:0.53;95%CI:-1.00,1.10;J45 SD:0.52;95%CI:-1.00,1.00).CONCLUSION:The two autorefractors are consistent with each other,as the differences in SE,DS,and DC were within the clinically acceptable *** can compare the data measured by either device in different studies and use the two devices in the same study to generate a dataset that can be analyzed ***,the J0 and J45 vectors are unreliable and should not be used to assess astigmatism.

关键词： refractive error autorefractors school-age myopia children

Research on Hepatocyte Regulation of PCSK9-LDLR and Its Related Drug Targets

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第7期30卷 664-672页

作者： liu Su-su YU Tong QIAO yan-fang GU shu-xiao CHAI Xin-lou School of Traditional Chinese Medicine Beijing University of Traditional Chinese MedicineBeijing102401China

The prevalence of hyperlipidemia has increased significantly due to genetic, dietary, nutritional and pharmacological factors, and has become one of the most common pathological conditions in humans. Hyperlipidemia can lead to a range of diseases such as atherosclerosis, stroke, coronary heart disease, myocardial infarction, diabetes, and kidney failure, etc. High circulating low-density lipoprotein cholesterol (LDL-C) is one of the causes of hyperlipidemia. LDL-C in the blood binds to LDL receptor (LDLR) and regulates cholesterol homeostasis through endocytosis. In contrast, proprotein convertase subtilisin/kexin type 9 (PCSK9) mediates LDLR degradation via the intracellular and extracellular pathways, leading to hyperlipidemia. Targeting PCSK9-synthesizing transcription factors and downstream molecules are important for development of new lipid-lowering drugs. Clinical trials regarding PCSK9 inhibitors have demonstrated a reduction in atherosclerotic cardiovascular disease events. The purpose of this review was to explore the target and mechanism of intracellular and extracellular pathways in degradation of LDLR and related drugs by PCSK9 in order to open up a new pathway for the development of new lipid-lowering drugs.

关键词： hyperlipidemia proprotein convertase subtilisin/kexin type 9 low-density lipoprotein receptor intracellular pathway extracellular pathway

维普期刊数据库

Comment on“Robotic surgery and liver transplantation:A single-center experience of 501 robotic donor hepatectomies”

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 109-110页

作者： Xiang-yan liu Yun-yang Xu Ze Xiang shu-Sen Zheng shulan(Hangzhou)Hospital Affiliated to Zhejiang shuren University shulan International Medical College Hangzhou 310015China Zhejiang University School of Medicine Hangzhou 310009China

To the Editor:We read with great interest the article by Schulze et ***“Robotic surgery and liver transplantation:A single-center experience of 501 robotic donor hepatectomies”[1].It is the first single-center report including over 500 fully robotic donor *** the donors,the overall complication rate was 6.4%(n=32).Postoperative self-limiting bleeding(0.4%)and bile leakage from the resection plane(1.8%)were rare.

关键词： robotic Robotic center

维普期刊数据库

The identification of AMZ2 as a candidate causative gene in a severe teratozoospermia patient characterized by vacuolated spermatozoa

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2024年第1期26卷 107-111页

作者： liu liu Jing yang Wen-Jing Zhang Yi-Ling Zhou Gui-Jun Zhao Ya Huang shu-yan Tang Obstetrics and Gynecology Hospital Fudan UniversityShanghai 200011China Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases Shanghai 200011China State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development Department of Computational BiologySchool of Life SciencesFudan UniversityShanghai 200436China Shanghai Towako Hospital Shanghai 200131China Shanghai Institute of Medical Genetics Shanghai Children's HospitalShanghai Jiao Tong UniversityShanghai 200040China

Teratozoospermia with cephalic defects is one of the most severe types of sperm defects known to *** several monogenic factors are linked to cephalic abnormalities,such as globozoospermia and macrozoospermia,the genetic cause of vacuolated spermatozoa remains inadequately ***,we analyzed whole-exome sequencing(WES)data for an individual from a consanguineous family with severely vacuolated *** analysis revealed a novel homozygous c.520A>G(***174Ala)variant in the archaelysin family metallopeptidase 2(AMZ2),a gene that encodes a zinc metalloprotease previously shown to be highly expressed in the testes and *** algorithms predicted this variant to be a damaging *** with an autosomal recessive mode of inheritance,this variant was inherited from heterozygous parental *** investigate the potential pathogenicity of the identified variant,we compared the AMZ2 expression in sperm cells from the patient with the AMZ2 variant and from a healthy *** analysis revealed that the homozygous missense variant in AMZ2 abolished AMZ2 expression in the *** findings reveal a candidate causative gene for vacuolated spermatozoa.

关键词： AMZ2 male infertility sperm quality teratozoospermia