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Gut microbiome:New perspectives for type 2 diabetes prevention and treatment

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World Journal of Clinical Cases 2023年第31期11卷 7508-7520页

作者： shu-xiao li Yan Guo School of Clinical Medicine Changchun University of Traditional Chinese MedicineChangchun 130000Jilin ProvinceChina

Type 2 diabetes mellitus(T2DM),which is distinguished by increased glucose levels in the bloodstream,is a metabolic disease with a rapidly increasing incidence ***,the etiology and characteristics of the mechanism of T2DM remain ***,abundant evidence has indicated that the intestinal microbiota is crucially involved in the initiation and progression of *** gut microbiome,the largest microecosystem,engages in material and energy metabolism in the human *** this review,we concentrated on the correlation between the gut flora and ***,we summarized the pathogenesis involving the intestinal flora in T2DM,as well as therapeutic approaches aimed at modulating the gut microbiota for the management of *** the analysis presented here,we draw attention to further exploration of these research directions.

关键词： Microbial metabolites Intestinal flora Probiotics Insulin resistance Type 2 diabetes

Efects of thermal aging temperature and Cr content on phase separ-ation kinetics in Fe-Cr alloys simulated by the phase feld method

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International Journal of Minerals,Metallurgy and Materials 2013年第11期20卷 1067-1075页

作者： shu-xiao li Hai-long Zhang Shi-lei li Yan-li Wang Fei Xue Xi-tao Wang State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Suzhou Nuclear Power Research Institute

Phase field simulations of phase separation in Fe-Cr binary alloys were performed by using the Cahn-Hilliard diffusion function. A new mobility model in relation to aging temperature and Cr content was used in the simulations. Two alloys of Fe-30at%Cr and Fe-35at%Cr were investigated at two different aging temperatures of 573 and 673 K. The phase separation kinetics was found to consist of three stages： wavelength modulation, amplitude increase, and coarsening of Cr-enriched regions. A higher thermal aging temperature accelerated the phase separation and increased the wavelength of concentration fluctuation. While the effect of Cr content on the phase separation kinetics was slight, Fe-Cr alloys with a higher Cr content were found to generate a larger number and a finer size of Cr-enriched regions. The simulation results provide consultation for design and safe operation of duplex stainless steel pipes in nuclear power plants.

关键词： stainless steel duplex steel phase separation kinetics nuclear power plants

Ob ject Tracking with Dual Field-of-view Switching in Aerial Videos

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International Journal of Automation and computing 2016年第6期13卷 565-573页

作者： Yi Song shu-xiao li Cheng-Fei Zhu Hong-Xing Chang The Integrated Information System Research Center Institute of AutomationChinese Academy of Science

Visual object tracking plays an important role in intelligent aerial surveillance by unmanned aerial vehicles（UAV）. In ordinary applications, aerial videos are captured by cameras with a fixed-focus lens or a zoom lens, for which the field-of-view（FOV）of the camera is fixed or smoothly changed. In this paper, a special application of the visual tracking in aerial videos captured by the dual FOV camera is introduced, which is different from ordinary applications since the camera quickly switches its FOV during the capturing. Firstly, the tracking process with the dual FOV camera is analyzed, and a conclusion is made that the critical part for the whole process depends on the accurate tracking of the target at the moment of FOV switching. Then, a cascade mean shift tracker is proposed to deal with the target tracking under FOV switching. The tracker utilizes kernels with multiple bandwidths to execute mean shift locating, which is able to deal with the abrupt motion of the target caused by FOV switching. The target is represented by the background weighted histogram to make it well distinguished from the background, and a modification is made to the weight value in the mean shift process to accelerate the convergence of the tracker. Experimental results show that our tracker presents a good performance on both accuracy and efficiency for the tracking. To the best of our knowledge, this paper is the first attempt to apply a visual object tracking method to the situation where the FOV of the camera switches in aerial videos.

关键词： tracker camera histogram captured surveillance switching intelligent cascade Tracking quickly

Charge noise acting on graphene double quantum dots in circuit quantum electrodynamics architecture

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Chinese Physics B 2018年第7期27卷 152-157页

作者： Yan li shu-xiao li Hai-Ou li Guang-Wei Deng Gang Cao Ming xiao Guo-Ping Guo CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China

We investigate the dephasing mechanisms induced by the charge noise and microwave heating effect acting on a graphene double quantum dot （DQD） capacitively coupled to a microwave resonator. The charge noise is obtained from DC transport current, and its contribution to dephasing is simultaneously determined by the amplitude response of the microwave resonator. A lowfrequency 1/f-type noise is demonstrated to be the dominant factor of the dephasing of graphene DQD. Furthermore, when the applied microwave power is larger than -90 dBm, the dephasing rate of graphene DQD increases rapidly with the increase of microwave power, and fluctuates slightly with the applied microwave power smaller than -90 dBm. Our results can be applied to suppress the impeditive influence on the dephasing of graphene-based devices associated with microwave input in the perspective investigations.

关键词： quantum dot microwave resonator charge noise graphene

Intravenous tirofiban therapy for patients with capsular warning syndrome

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Stroke & Vascular Neurology 2019年第1期4卷 22-27页

作者： Wei li Ya Wu xiao-shu li Cheng-Chun liu shu-Han Huang Chun-Rong liang Huan Wang li-li Zhang Zhi-Qiang Xu Yan-Jiang Wang Meng Zhang Department of Neurology Daping Hospital&Research Institute of SurgeryThe Army Military Medical UniversityChongqingChina

Background Capsular warning syndrome(CWS)is defined as recurrent episodes of transient ischaemic attacks≥3 times during a short time *** is no effective therapy to stop these ***,herein,report our experience of using intravenous tirofiban to treat *** All patients with CWS in our hospital from January 2013 to September 2017 were *** in tirofiban group(T-group)were treated by intravenous tirofiban at 0.4μg/kg/min for 30 min followed by 0.1-0.15μg/kg/min *** treatments(non-T-group)included thrombolytic,oral antiplatelet agents and *** haemorrhage(ICH),systematic bleeding,new attacks after treatment,National Institutes of Health Stroke Scale(NIHSS)scores at 24 hours and modified Rankin Scales(mRSs)at 3 months were *** statistics were used for *** Of 23 patients qualified(15 in T-group,8 in non-T-group),the duration of symptoms ranged from 2 to 100 min before *** treatment,in T-group,four patients(26.7%)had recurrent attacks,and NIHSS scores were 0 in 11 patients(73.3%)at 24 *** patients reached a favourable outcome(mRS≤2) at 3 *** non-T-group,five patients(62.5%)had new *** scores were 0 in two patients(25%)at 24 *** 3 months,seven patients(87.5%)reached a favourable *** ICH nor systematic bleeding or thrombocytopaenia occurred in both groups of *** Intravenous tirofiban can be a potentially effective and safe therapy to stop early symptomatic fluctuations and shorten the duration of functional deficits in patients with CWS.

关键词： patients Intravenous intravenous

Effects of Ru on microstructure stability and mechanical properties of Ni3Al single crystal alloy

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Progress in Natural Science:Materials International 2011年第4期21卷 286-292页

作者： shu-suo li,xiao-ying XIE,li-wu JIANG,Ya-fang HAN School of Materials Science and Engineering,Beihang University,Beijing 100191,China School of Materials Science and Engineering Beihang University Beijing 100191 China

The effect of Ru on microstructure stability and stress rupture properties of a Ni3Al single-crystal alloy was investigated. The experimental results showed that the addition of 2%Ru(mass fraction) improved the microstructure stability due to the restraint of harmful Y-NiMo phase formation during the thermal exposure at the high temperature above 1 000℃.And the reason may be that the addition of Ru increased the degree of Mo supersaturation in bothγandγ’ phases,and hence suppressed the precipitation of Y-NiMo *** results of stress rupture tests under the testing condition of 1100℃,120 MPa showed that the addition of 2% Ru in the alloy improved the stress rupture lives significantly for thermal exposed *** improvement of the stress rupture properties may be attributed to the restraint of Y-NiMo phase precipitation and growth by the addition of the proper amount Ru.

关键词： Ni3Al microstructure stability Ru Y-NiMo phase stress rupture

Synthesis, Crystal Structure and Thermoanalysis of o-vanillin-ethylenediamine Schiff Base Copper( Ⅱ ) Complex

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Chemical Research in Chinese Universities 1993年第3期9卷 194-200页

作者： liU De-xin, CUI Xue-gui, li shu-Ian, li xiao-yan and SUN Hong-jian (Department of Chemistry, Shandong University, Jinan, 250100)

The crystal structure of the title compound [Cu (o-vanillin-ethylenediamine) (H2O)] is described. The complex crystallizes in the orthorhombic system, space group Pbn21 with formula = CuC18H20N2O5, cell dimensions are: a = 0.7490(3) nm, b = 0.9256(2) nm, c=2. 4691(6) nm, V=1.712 nm3, Z = 4, Dc=l.51 g/cm3. The kinetics of thermal decomposition of the complex was studied under the non-isothermal condition by TG. Kinetic parameters were obtained from the analysis of the TG, DTG curves by integral and differential methods. By comparison of the kinetic parameters, the most probable mechanism function is f(α) = (3/2) (1-α)[-ln(1-α)]1/3, and the mathematical expression for the kinetic compensation effect is lnA = 0. 201E+0. 531.

关键词： Synthesis Crystal structure Thermoanalysis

Enhanced Biological Phosphorus Removal with Pseudomonas putida GM6 from Activated Sludge

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Pedosphere 2007年第5期17卷 624-629页

作者： CAI Tian-Ming GUAN li-Bo CHEN li-Wei CAI shu li xiao-Dan CUI Zhong-li li shun-Peng Department of Microbiology College of Life Science Nanjing Agricultural University Nanjing 210095 （China） Key Laboratory of Microbiological Engineering of Agricultural Environment Ministry of Agriculture Nanjing 210095 （China）不详

The enhanced biological phosphorus removal （EBPR） method is widely adopted for phosphorus removal from wastewater, yet little is known about its microbiological and molecular mechanisms. Therefore, it is difficult to predict and control the deterioration of the EBPR process in a large-scale municipal sewage treatment plant. This study used a novel strain isolated in the laboratory, Pseudomonas putida GM6, which had a high phosphate accumulating ability and could recover rapidly from the deteriorated system and enhance the capability of phosphorus removal in activated sludge. Strain GM6 marked with gfp gene, which was called GMTR, was delivered into a bench-scale sequencing batch reactor （SBR） of low efficiency, to investigate the colonization of GMTR and removal of phosphorus. After 21 days, the proportion of GMTR in the total bacteria of the sludge reached 9.2%, whereas the phosphorus removal rate was 96%, with an effluent concentration of about 0.2 mg L^-1. In the reactor with the addition of GMTR, phosphorus was removed quickly, in 1 h under anaerobic conditions, and in 2 h under aerobic conditions. These evidences were characteristic of EBPR processes. Field testing was conducted at a hospital sewage treatment facility with low phosphorus removal capability. Twentyone days after Pseudomonas putida GM6 was added, effluent phosphorus concentration remained around 0.3 mg L^-1, corresponding to a removal rate of 96.8%. It was therefore demonstrated that Pseudomonas putida GM6 could be used for a quick startup and enhancement of wastewater biological phosphorus removal, which provided a scientific basis for potential large-scale engineering application.

关键词： activated sludge colonization enhanced biological phosphorus removal Pseudomonas putida GM6

Forest characteristics and population structure of a threatened palm tree Caryota obtusa in the karst forest ecosystem of Yunnan,China

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Journal of Plant Ecology 2022年第4期15卷 829-843页

作者： Cindy Q.Tang Xia Lu Min-Rui Du shu-li xiao shuaifeng li Peng-Bin Han Jia-Le Zeng Jian-Ran Wen Shi-Qian Yao You-Cai Shi Yun-Fang li Ming-Chun Peng Chong-Yun Wang Zhi-Ying Zhang Institute of Ecology and Geobotany College of Ecology and Environmental ScienceYunnan UniversityKunming 650504China Research Institute on Resource Insects Chinese Academy of ForestryKunming 650224China Management Office of Yunlong Tianchi National Nature Reserve GuolangDali PrefectureYunnan 672700China

Caryota obtusa of Arecaceae is a fascinating palm tree native to southwestern China,India,Myanmar,Thailand,Laos and *** is an economically important and threatened species and appears as a canopy dominant in some karst areas in *** aim to clarify the forest structure,species diversity,population status and regeneration dynamics of *** in the karst forest ecosystem of Yunnan,*** established 56 vegetation plots dominated by *** in 10 counties of southern *** on the plot data,we analyzed the community stratification,floristic composition and ***’s population *** used questionnaires to interview local people and recorded the human activity history in ***-dominated *** obtusa palm forests were distributed on limestone mountain slopes and *** were seven forest community *** stratification of each community included arborous layer,shrub layer and *** communities had rich species *** all the plots as a whole of each community type,Shannon–Wiener diversity index of either woody or herbaceous species ranged from 2.1 to *** diameter at breast height(DBH)-class frequency distribution of *** was a multimodal *** regeneration was sporadic and dependent on intermediate natural *** the current population structure,a number of *** trees with small DBHs consisted mainly of the forest communities with no or a slight degree of human *** human activities terribly hindered recruitment of ***,followed by the medium intensity of human activities.

关键词： Caryota obtusa community structure species diversity population structure regeneration dynamics human disturbance