检索结果-南通市图书馆

The secretory function of adipose tissues in metabolic regulation

在线全文

学校读者我要写书评

暂无评论

Life Metabolism 2024年第2期3卷 9-23页

作者： Yang liu shu-Wen Qian Yan Tang Qi-Qun Tang Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences and Department of Endocrinology and Metabolism of Zhongshan HospitalFudan UniversityShanghai 200032China

In addition to their pivotal roles in energy storage and expenditure,adipose tissues play a crucial part in the secretion of bioactive molecules,including peptides,lipids,metabolites,and extracellular vesicles,in response to physiological stimulation and met-abolic *** secretory factors,through autocrine and paracrine mechanisms,regulate various processes within adipose *** processes include adipogenesis,glucose and lipid metabolism,inflammation,and adaptive thermogenesis,all of which are essential for the maintenance of the balance and functionality of the adipose tissue micro-environment.A subset of these adipose-derived secretory factors can enter the circulation and target the distant tissues to regulate appetite,cognitive function,energy expenditure,insulin secretion and sensitivity,gluconeogenesis,cardiovascular remodeling,and exercise *** this review,we highlight the role of adipose-derived secretory factors and their signaling pathways in modulating meta-bolic ***,we delve into the alterations in both the content and secretion processes of these factors under various physiological and pathological conditions,shedding light on potential pharmacological treatment strategies for related diseases.

关键词： adipokines autocrine paracrine endocrine metabolic regulation

Photon counting technique as a potential tool in micro-defect detection of epoxy insulation pull rod in gas-insulated switchgears

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High Voltage 2024年第2期9卷 267-274页

作者： Xianhao Fan shu Niu Hanhua Luo Jizhong Liang Fang liu Wenqiang Li Weidong liu Wensheng Gao Yulong Huang Chuanyang Li Jinliang He School of Electrical Engineering Tsinghua UniversityBeijingChina Electric Power Research Institute Shangxi Power Grid CorporationTaiyuanShanxiChina Shandong Taikai Electrical Insulation Co. Ltd.TaianShandongChina

The micro-defects in epoxy-based insulation materials generate a local high electric field which results in continuous degradation,seriously endangering the insulation system of gas-insulated switchgears.A highly sensitive detection technique is reported for micro-defects of insulation pull rods based on the photon counting(PC)*** re-sults demonstrated that for an epoxy-based insulation pull rod,the photons released during electroluminescence and ionisation at 2 kV,which is less than the partial discharge inception voltage,can be clearly *** findings presented a strong correlation between photon counts and defect *** has been conducted to elucidate the mechanism behind defect-induced PC,employing the amplification of ionising luminescence through electric field distortion induced by micro defects and the augmentation of electroluminescence through the aggregation of trap *** this regard,the authors verified that PC can serve as a potential tool in the detection of micro-insulation defects,which also has huge potential in online insulation condition monitoring.

关键词： technique. insulation defect

Design and prototyping of the readout electronics for the transition radiation detector in the high energy cosmic radiation detection facility

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第4期35卷 189-199页

作者： Jie-Yu Zhu Yang-Zhou Su Hai-Bo Yang Fen-Hua Lu Yan Yang Xi-Wen liu Ping Wei shu-Cai Wan Hao-Qing Xie Xian-Qin Li Cong Dai Hui-Jun Hu Hong-Bang liu shu-Wen Tang Cheng-Xin Zhao Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China

The high energy cosmic-radiation detection(HERD)facility is planned to launch in 2027 and scheduled to be installed on the China Space *** serves as a dark matter particle detector,a cosmic ray instrument,and an observatory for high-energy gamma rays.A transition radiation detector placed on one of its lateral sides serves dual purpose,(ⅰ)calibrating HERD's electromagnetic calorimeter in the TeV energy range,and(ⅱ)serving as an independent detector for high-energy gamma *** this paper,the prototype readout electronics design of the transition radiation detector is demonstrated,which aims to accurately measure the charge of the anodes using the SAMPA application specific integrated circuit *** electronic performance of the prototype system is evaluated in terms of noise,linearity,and *** the presented design,each electronic channel can achieve a dynamic range of 0–100 fC,the RMS noise level not exceeding 0.15 fC,and the integral nonlinearity was<0.2%.To further verify the readout electronic performance,a joint test with the detector was carried out,and the results show that the prototype system can satisfy the requirements of the detector's scientific goals.

关键词： HERD Dark matter particle detection TRD Readout electronics SAMPA Data acquisition Performance test

基于“1+N”功能定位的“中文+职业技能”国际推广基地建设研究

在线全文

学校读者我要写书评

暂无评论

职业技术教育 2024年第5期45卷 64-70页

作者：刘丹张森刘澍河北师范大学石家庄职业技术学院石家庄050024 河北师范大学外国语学院

建设“中文+职业技能”国际推广基地是增强职业教育全球适应性的重要举措,也是国际中文教育突破发展瓶颈的创新路径,更是服务“一带一路”倡议的重要抓手。功能定位是基地实践的出发点和着力点。“中文+职业技能”国际推广基地“1+N”... 详细信息

建设“中文+职业技能”国际推广基地是增强职业教育全球适应性的重要举措,也是国际中文教育突破发展瓶颈的创新路径,更是服务“一带一路”倡议的重要抓手。功能定位是基地实践的出发点和着力点。“中文+职业技能”国际推广基地“1+N”功能定位是指基地应以培养“中文+”国际职业人才为核心功能,兼具语言与文化传播、国际化职教资源开发、国际化职教师资培育以及国际化职业汉语能力考核与职业等级鉴定等功能。“中文+职业技能”国际推广基地的组织架构也要依循“1+N”的模式特点,以人才培养部门为核心,同时建设国际化职教资源开发部门、国际化职教师资培育部门、国际化职业汉语能力考核与职业资格等级鉴定部门等。

关键词： “中文+职业技能” 国际推广基地功能定位建设架构

Experimental Study on Vortex-Induced Vibration of Rough Risers with Coupling Interference Effect Under Side-by-Side Arrangement

在线全文

学校读者我要写书评

暂无评论

China Ocean Engineering 2024年第1期38卷 18-28页

作者： HU Ze-bo liu Zhen LI Peng GUO Hai-yan WANG shu-bing REN Xiao-hui HOU Hao WANG Ye-shuo College of Civil Engineering and Architecture Shandong University of Science and TechnologyQingdao 266590China Qingdao Key Laboratory of Marine Civil Engineering Materials and Structures Qingdao 266590China College of Engineering Ocean University of ChinaQingdao 266100China CHEC Dredging Co. LtdShanghai 200136China

A vortex-induced vibration(VIV)experiment of rough risers with coupling interference effect under a side-by-side arrangement was carried out in a wave-current combined *** roughness of the riser was characterized by arranging different specifications of surface attachments on the surface of the *** risers with three different roughnesses were arranged side by side with smooth risers to explore the VIV response of the riser under the combined action of roughness and interference effect,and to reveal the coupling mechanism between roughness and interference *** experimental results show that,compared with that of a smooth riser,the VIV of a rough riser under the coupling interference effect has a wider"lock-in"region,and the displacement decreases more significantly at a high reduced velocity,which is more likely to excite higher-order modes and frequency *** addition,the displacement response and frequency response of the smooth riser are not significantly affected by wake interference from the rough riser,which is caused by the decrease of the wake region due to the delay of the boundary layer separation point of the rough riser.

关键词： marine riser vortex-induced vibration side-by-side arrangement roughness interference effect

A 30-year overview of sodium-ion batteries

在线全文

学校读者我要写书评

暂无评论

Carbon Energy 2024年第6期6卷 56-98页

作者： Yun Gao Hang Zhang Jian Peng Lin Li Yao Xiao Li Li Yang liu Yun Qiao shu-Lei Chou School of Environmental and Chemical Engineering Shanghai UniversityShanghaiChina College of Chemistry and Materials Engineering Wenzhou UniversityWenzhouZhejiangChina Institute for Superconducting and Electronic Materials University of WollongongWollongongNew South WalesAustralia

Sodium-ion batteries(NIBs)have emerged as a promising alternative to commercial lithium-ion batteries(LIBs)due to the similar properties of the Li and Na elements as well as the abundance and accessibility of Na *** of the current research has been focused on the half-cell system(using Na metal as the counter electrode)to evaluate the performance of the cathode/anode/*** relationship between the performance achieved in half cells and that obtained in full cells,however,has been neglected in much of this ***,the trade-off in the relationship between electrochemical performance and cost needs to be given more ***,systematic and comprehensive insights into the research status and key issues for the full-cell system need to be gained to advance its ***,this review evaluates the recent progress based on various cathodes and highlights the most significant challenges for full *** strategies have also been proposed to enhance the electrochemical performance of NIBs,including designing electrode materials,optimizing electrolytes,sodium compensation,and so ***,perspectives and outlooks are provided to guide future research on sodium-ion full cells.

关键词： commercial application electrode electrolyte sodium-ion full cell strategies

2:17-type SmCo permanent magnets with controllable remanence temperature coefficients via substitution of heavy rare earth elements

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rare Metals 2024年第8期43卷 3990-3996页

作者： Jia-Yi Huang shu-Lan Zuo Qi Zhang Hong-Yang Dai Lei Yang Jing-Hua liu Cheng-Bao Jiang Key Laboratory of Aerospace Materials and Performance(Ministry of Education) School of Materials Science and EngineeringBeihang UniversityBeijing 100191China

Permanent magnets that can maintain a constant magnetic flux over a wide temperature range are highly desirable in certain applications such as precision instruments.2:17-type SmCo permanent magnets are promising for such instruments owing to their excellent high-temperature magnetic properties that can be further manipulated byadding heavy rare earth elements (HREs).

关键词： magnets permanent earth

Two different autorefractors for vision screening in children and adolescents

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第2期17卷 331-338页

作者： Xiao-Jun Chen Lin-Jie liu Bing Sun Dan-Dan Jiang shu-shu Zuo Yan-Hui Wang Chun-Hua Zhang Yan-Yan Chen School of Optometry and Ophthalmology Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina

AIM:To compare the consistency of two autorefractors(Tianle RM-9000 and Topcon KR-800)for school-age myopia children,and to provide a basis for largescale data analysis and ***:The refractive error in 909 subjects(age 4–18y)were measured using both autorefractors without *** data were analyzed using Fourier decomposition and the correlation coefficients,intraclass correlation coefficients(ICC),and Bland-Altman limits of agreement(LoA)for each parameter were ***:There was a strong correlation between the spherical equivalent(SE),sphere diopter(DS),and cylinder diopter(DC)readings of the Tianle RM-9000 and those of the Topcon KR-800,with correlation coefficient values of 0.98,0.98 and 0.83 and ICC values of 0.99,0.99 and 0.93,***,the correlation coefficients and ICC values of J0 and J45 were unreliable(R=-0.004,-0.034;both ICC<0.10).Bland-Altman analysis revealed that SE,DS,and DC measured by the Tianle RM-9000 were significantly biased toward myopia compared with the Topcon KR-800,and the mean differences were-0.072,-0.026,-0.091 D,respectively(all P<0.01).The minimum absolute value of the difference within the 95%LoA for SE,DS,and DC was 0.63 D,0.50 D,0.62 D,respectively;all these values were in the clinically acceptable *** J0 and J45,the mean differences were close to zero(P=0.43,0.84);however,the 95%LoA were relatively wide(J0 SD:0.53;95%CI:-1.00,1.10;J45 SD:0.52;95%CI:-1.00,1.00).CONCLUSION:The two autorefractors are consistent with each other,as the differences in SE,DS,and DC were within the clinically acceptable *** can compare the data measured by either device in different studies and use the two devices in the same study to generate a dataset that can be analyzed ***,the J0 and J45 vectors are unreliable and should not be used to assess astigmatism.

关键词： refractive error autorefractors school-age myopia children

First-principles study on the diffusion behavior of Cs and I in Cr coating

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第6期35卷 177-188页

作者： shu-Ying Lin Xiao-Jing Li Lin-Bing Jiang Xi-Jun Wu Hui-Qin Yin Yu Ma Wen-Guan liu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of South ChinaHengyang 421001China

Cs and I can migrate through fuel-cladding interfaces and accelerate the cladding corrosion process induced by the fuel-cladding chemical *** coating has emerged as an important candidate for mitigating this chemical *** this study,first-principles calculations were employed to investigate the diffusion behavior of Cs and I in the Cr bulk and grain boundaries to reveal the microscopic interaction mitigation mechanisms at the fuel-cladding *** interaction between these two fission products and the Cr coating were studied systematically,and the Cs and I temperature-dependent diffusion coefficients in Cr were obtained using Bocquet’s oversized solute-atom model and Le Claire’s nine-frequency model,*** results showed that the Cs and I migration barriers were significantly lower than that of Cr,and the Cs and I diffusion coefficients were more than three orders of magnitude larger than the Cr self-diffusion coefficient within the temperature range of Generation-IV fast reactors(below 1000 K),demonstrating the strong penetration ability of Cs and ***,Cs and I are more likely to diffuse along the grain boundary because of the generally low migration barriers,indicating that the grain boundary serves as a fast diffusion channel for Cs and I.

关键词： First-principles calculation Fuel cladding chemical interaction Cr coating Fission product Diffusion Grain boundary