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The Up-conversion Laser Properties of a Non-polar Organic Dye and the Influence of Solvents and Pumping Wavelengths

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Chinese Chemical Letters 2006年第1期17卷 81-84页

作者： Xiao Qiang YU xian ZHANG Gui Bao xu Hua Ping ZHAO Wei HE Zong shu SHAO xian Gang xu Min Hua JIANG The National Key Lab of Crystal Materials Shandong University Jinan 250100

A non-polar organic dye, E, E-1, 4-bis[4＇-（N,N-dibutylamino）styryl]-2,5-dimethoxybenzene （DBASDMB）, has been synthesized and characterized, and its structure has been determined. Pumped with a 200fs pulse this dye showed the up-conversion laser properties. The influences of various organic solvents and different pumping wavelength on the laser properties have been demonstrated.

关键词： Up-conversion laser two-photon absorption non-polar organic dye.

Diffusion of Innovative Behavior of the Public Toward Preparing FEMKs:From Innovative Characteristics to Personal Risk Perception and Behavioral Intention

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Psychosomatic Medicine Research 2021年第1期3卷 16-23页

作者： shu-xian xu Ting-Yu Duan shu-Ting Wei Xi-Zhe He Ru-Yi Hou Yi-Bo Wu School of pharmacy Shenyang pharmaceutical universityBenxi 117004China Department of humanities arts and mediaChangzhi Medical CollegeChangzhi 046000China Department of clinical medicine School of Basic MedicineShandong UniversityJinan 250100China School of pharmacy Jiangxi University of Traditional Chinese MedicineNanchang 330004China Key Research Base of Philosophy and Social Sciences in Shaanxi Province Health Culture Research Center of ShaanxiXi'an 712046China Peking University Health Science Center Beijing 100191China

Objective:The study aims to apply diffusion of innovation theory and structural equation modeling(SEM)to explore the current situation of personal risk perception and preparation of family emergency medicine kits(FEMKs)in Shanxi Province during the period of ***,the study intends to analyze the impact of innovation characteristics and risk perception to provide reference for the future popularization of FEMKs and the formulation of relevant ***:A total of 1,606 permanent residents in Shanxi Province were selected as *** was used to analyze the relationship among innovation characteristics,personal risk perception,and behavioral ***:The results demonstrate that only observability(λ=0.968)exerted a significant direct impact on the public's behavior of preparing *** risk perception(λ=0.334)can have a significant direct impact on behavioral *** advantage,compatibility,and convenience of use exerted significant impacts on behavioral intention by influencing individual perceived risk(mediating effects=0.237,0.892,and 1.044,respectively).Conclusion:Residents are undergoing a period of change(i.e.,from the contemplation to the preparation stage).Thus,innovative characteristics can directly influence the behavior or behavioral intention of preparing FEMKs by influencing the public's risk *** the future,studies should focus on publicity and education of the behavior of preparing FEMKs to increase the awareness of residents and effectively improve the FEMKs level of importance given to this behavior.

关键词： COVID-19 Emergency medicine kit Diffusion of innovations Structural equation model Psychosomatic medicine Affecting factors

Going-out Behaviors of Patients with Chronic Diseases When Purchasing Drugs During Covid-19

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Psychosomatic Medicine Research 2021年第2期3卷 69-76页

作者： Si-Tong Liu shu-xian xu Hai-Ping xu Lin-Ling Shi Zhe-Feng Liu Xiao-Lin xu Yi-Bo Wu Department of Pharmacy Administration and Clinical Pharmacy School of Pharmaceutical Sciences Peking UniversityBeijing 100191China. Evidence-based Communication and Information Management Research Center Liaoning Technical University College of the Media and ArtsFuxin 123000China. School of pharmacy Shenyang Pharmaceutical UniversityBenxi 117004China. School of Pharmaceutical Sciences Shandong UniversityShandong 250012China. Party Committee Propaganda Department of Affiliated Hospital of Nantong University Nantong 226019China. xiangya School of Public Health of Central South University Changsha 410000China. Department of Pharmacy Beijing Children’s HospitalCapital Medical UniversityBeijing 100145China. School of Public Health Peking UniversityBeijing 100191China Key Research Base of Philosophy and Social Sciences in Shanxi Province Health Culture Research Center of ShanxiXi'an 712046China).

Objective:This study sheds light on the going-out behaviors of patients with chronic diseases when purchasing drugs during COVID-19,explores what factors influence these behaviors,and makes recommendations to guarantee the pharmaceutical treatment of patients with chronic ***:A questionnaire based on the health belief model(HBM)was designed and convenience sampling was employed to administer the online *** influence of the respondents’demographic information on their going-out behaviors was analyzed by means of multiple linear regression.A structural equation model(SEM)was constructed to explore how health beliefs related to chronic diseases and COVID-19 influenced patients’going-out ***:A total of 869 questionnaires were *** structural equation model revealed that while the severity of the chronic disease had a direct positive effect on going-out behaviors(l=0.106),chronic disease behavior barriers had a direct negative effect on their going-out behaviors(l=-0.204).Conclusion:Educational background,co-living situation,and income could influence patients’going-out *** severity of the chronic disease and chronic disease behavior barriers directly affected patients’going-out ***,patients’health beliefs about COVID-19 ultimately affected their going-out behaviors by influencing their health beliefs related to chronic disease.

关键词： COVID-19 Chronic disease Going-out behaviors Influencing factors

Construction of an intelligent patient satisfaction assessment system and its application in emergency management

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TMR Clinical Research 2020年第1期3卷 30-30,31-35页

作者： Yi-Bo Wu Jin-Yi Meng Hong-xue Chen Dong-Yun Li shu-xian xu Tao Wang Department of Pharmacy Administration and Clinical Pharmacy School of Pharmaceutical SciencesPeking UniversityBeijingChina College of Humanities and Social Sciences Harbin Medical University HarbinChina School of Pharmacy Shenyang Pharmaceutical UniversityBenxiChina Department of Emergency Shanghai East HospitalTongji University School of MedicineShanghaiChina College of Art and Media Tongji UniversityShanghaiChina

Hospital emergency management work is of great importance which not only related to the life and health of the people but also related to social *** is necessary to construct and improve the patient satisfaction assessment system so that doctors and patients can interact in a timely and effective manner,and the hospital can alert or respond *** study constructs a closed-loop emergency management system consisting of patient-end,data center and decision-making-end,and apply the feedback information to hospital emergency *** the preliminary applications,the system has a significant effect on the hospital emergency management *** researchers will improve the system in the follow-up study。

关键词： Hospital Emergency Management Patient Satisfaction Feedback Mechanism

Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong Xing Xinzhu Liu xiandeng Li Mi Li xian Wu Xiaohui Huang Ajing xu Yan Liu Jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

常曲率大深宽比河湾拟序扰动结构与床面响应关系探讨

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应用数学和力学 2016年第10期37卷 1100-1117页

作者：高术仙徐海珏白玉川水利工程仿真与安全国家重点实验室(天津大学) 天津300072 天津大学河流海岸工程泥沙研究所天津300072

蜿蜒河流床面形态既是其复杂动力结构响应的结果,同时也是决定河流进一步演化方向的重要因素.以蜿蜒河流中一种典型的大深宽比河湾为背景,探索其动力结构与床面响应的关系,将黏性不可压缩流体方程、泥沙输移方程和床面变形方程耦合,通... 详细信息

蜿蜒河流床面形态既是其复杂动力结构响应的结果,同时也是决定河流进一步演化方向的重要因素.以蜿蜒河流中一种典型的大深宽比河湾为背景,探索其动力结构与床面响应的关系,将黏性不可压缩流体方程、泥沙输移方程和床面变形方程耦合,通过摄动方法求解床面响应,分析床面形态变化特性.研究成果显示在水流二维扰动作用下,河道中浅滩深槽呈现规则响应.当弯曲度等于0时,床面响应形态围绕河道中轴线基本呈反对称分布;当弯曲度不等于0时,床面响应形态呈不对称分布,中轴线向凹岸偏移.该文给出了由Reynolds(雷诺)数、扰动波数、床面形态增减率等构成的床面响应发展趋势稳定关系的判别方法.

关键词：蜿蜒河流大深宽比河湾扰动波床面动力响应

Toric人工晶状体植入治疗白内障合并角膜散光的疗效观察

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国际眼科杂志 2015年第11期15卷 1920-1922页

作者：邓国华周栋徐淑贤中国江苏省常州市第三人民医院眼科 213000

目的:探讨Toric人工晶状体植入治疗白内障合并角膜散光的临床疗效。方法:选择2013-06/2014-07在我院进行超声乳化白内障吸出及人工晶状体植入术合并角膜散光的白内障患者38例46眼作为研究对象,其中20例24眼患者植入Toric人工晶状体,18... 详细信息

目的:探讨Toric人工晶状体植入治疗白内障合并角膜散光的临床疗效。方法:选择2013-06/2014-07在我院进行超声乳化白内障吸出及人工晶状体植入术合并角膜散光的白内障患者38例46眼作为研究对象,其中20例24眼患者植入Toric人工晶状体,18例22眼患者植入Acrysof IQ人工晶状体,对两组患者的临床疗效进行分析。结果:两组患者术后裸眼视力进行比较,差异有统计学意义(F=5.783,P<0.05);观察组患者术后1wk,1、3mo裸眼视力明显高于术前,其差异均有统计学意义(P<0.05);观察组患者术后裸眼视力明显高于对照组,其差异有统计学意义(t=5.248,2.573,2.782;P均<0.05)。两组患者术后散光情况进行比较,差异有统计学意义(F=5.482,P<0.05);观察组患者术后1wk,1、3mo的散光改善情况明显优于手术前,其差异有统计学意义(P<0.05);观察组患者术后散光改善情况明显优于对照组,其差异有统计学意义(t=6.591、3.287、2.167,P均<0.05)。远视力研究中植入Toric人工晶状体有75%的患者不需要配戴眼镜。结论:Toric人工晶状体植入治疗白内障合并角膜散光具有良好的矫正作用,且能明显提高患者术后视觉治疗,有良好的预测性,因此值得在临床推广应用。

关键词： Toric人工晶状体白内障角膜散光

Trimetallic mesoporous PdCuRu for efficient formate electrosynthesis from polyethylene terephthalate recycling

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Science China Chemistry 2025年

作者： Yuting Li Huiqin Yao Lizhi Sun shu Han Xiaoxiang xu Guangyin Fan Ben Liu College of Chemistry and Materials Science Sichuan Normal University Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University School of Basic Medical Sciences Ningxia Medical University Department of Otorhinolaryngology-Head and Neck Surgery Zhongnan Hospital of Wuhan University

Electrochemical recycling of waste polyethylene terephthalate（PET） plastics represents a green and sustainable route to produce valuable fuels and address serious environmental issues. Despite some encouraged achievements, their progress is still slower because of the lack of highly active and selective electrocatalysts. Here, we reported an efficient PET recycling route with trimetallic PdCuRu mesoporous nanospheres（MSs） as a high-performance electrocatalyst that achieved selective electrosynthesis of valuable formate from PET hydrolysate（PETH） electrooxidation. Penetrated metal mesopores and trimetallic compositions of PdCuRu MSs synergistically optimized electronic structures of Pd sites and changed chemisorption properties of intermediates, which disclosed a high formate Faradic efficiency of 97% and impressive yield rate of 0.49 mmol h-1cm-2in an alkaline solution. Meanwhile, this electrocatalyst held good electrocatalytic stability, retaining high formate Faradic efficiency and yield rate even being performed for 10 cycles, which highlighted its potential applications for practical PET recycling. Our study provides a powerful strategy for designing high-performance electrocatalysts toward selective electro-synthesis of valuable fuels from various waste plastics.

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Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang Li Xiaomei Tang Jinyu Zeng Yige Song Chao xu Kai Zhao Guoqiang Liu Youming Lu Xinyan Li Kai shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury