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Incidence of unexplained intra-abdominal free fluid in patients with blunt abdominal trauma

Hepatobiliary & Pancreatic Diseases International 2009年第6期8卷 597-601页

作者： Chen, Zuo-Bing Zhang, Yun Liang, Zhong-Yan Zhang, Shao-Yang Yu, Wen-Qiao Gao, yuan Zheng, shu-sen Zhejiang Univ Sch Med Affiliated Hosp 1 Dept Gen Surg Hangzhou 310003 Zhejiang Peoples R China Zhejiang Univ Sch Med Affiliated Hosp 1 Dept Emergency Surg Hangzhou 310003 Zhejiang Peoples R China

BACKGROUND: Intra-abdominal free fluid is commonly caused by injuries of solid or hollow organs in patients suffering from blunt abdominal trauma (BAT). However, it presents a diagnostic dilemma for surgeons when free fluid is unexplained, especially in stable BAT patients. This study was to analyze the incidence of such unexplained free fluid in BAT patients and its diagnostic value in abdominal organ injury. METHODS: Altogether 597 patients with BAT who had been treated at our trauma center over a 10-year period were reviewed. Stable patients with free fluid but without free air or definite organ injury on abdominal computed tomography were studied. Clinical management and operative findings were analyzed. RESULTS: Thirty-four (5.70%) of the 597 patients met the inclusion criteria: 24 (4.02%) underwent therapeutic exploratory laparotomy: bowel injuries were found in 13, hepatic rupture in 3, colon rupture in 3, duodenal rupture in 2, spleen rupture in 1, pancreas rupture in 1, and gallbladder perforation in 1. In 2 patients, laparotomy was nontherapeutic. Those with moderate or large amounts of free fluid were more likely to suffer from a hollow viscus injury and have a therapeutic procedure. The mean time of hospital stay for the delayed laparotomy group was longer than that for the emergency group (19 5.12 vs. 12 2.24 days; t=2.73, P<0.01). CONCLUSIONS: There was a positive correlation between the amount of unexplained free fluid and the determination of intra-abdominal organ injury. The proportion of BAT patients who required surgical intervention was high, particularly those with a moderate or large amount of free fluid, and most of them suffered from a hollow organ injury. Emergency laparotomy is recommended for these patients.

关键词： blunt abdominal injury hepatic rupture hollow viscus free fluid computed tomography

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Solidification pattern and microstructures of AZ91D magnesium alloy through rheoforming

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Chinese Science Bulletin 2005年第16期50卷 1799-1804页

作者： WANG Wuxiao yuan sen JIANG Bailing JIE Wanqi College of Materials Science and Engineering Northwestern Polytechnical University Xi'an 710072 China School of Materials Science and Engineering Xi'an University ofTechnology Xi'an 710048 China

The optical microscope, SEM and EDS were adopted to analyze the rheoforming solidification morpholo-gies and microstructures of deformed AZ91D magnesium alloy after isothermal treatment in semisolid state. The re-sults show that primary α phase can be formed through attachment growth, when the liquid fraction is small; and primary α phase will grow in dendrites, when the liquid fraction is high. Eutectic solidification is carried out in the ways of both dissociated growth and symbiotic growth, de-pending on the morphology of primary α phase. Liquid with eutectic concentration solidifies into lamina eutectic. During solidification of the liquid pools inside grains, α phase can be formed through attachment growth. The eutectic solidifica-tion was mainly carried out in the dissociated pattern.

关键词：镁合金凝固模式微观结构等温线半固体

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Donning and doffing of personal protective equipment protocol and key points of nursing care for patients with COVID-19 in ICU

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Stroke & Vascular Neurology 2020年第3期5卷 302-307页

作者： Li yuan shu Chen Yafang Xu Department of Nursing Huashan HospitalFudan UniversityShanghaiChina Department of Infectious Diseases Huashan HospitalFudan UniversityShanghaiChina

Coronavirus pandemic is the most important public health event in the world *** with coronavirus disease 2019(COVID-19)in a critical state are at risk of progressing rapidly into many serve complications;they require a high level of care from ICU *** to avoid the virus to infect health care worker is also a critical *** on the summarized experience of Chinese health workers,literature review and clinical practice,this article introduced donning and doffing of personal protective equipment(PPE)protocol and some keypoints of nursing critical care in patients with coronavirus disease 2019(COVID-19):caring of patients requiring intubation and ventilation,venous thromboembolism(VTE)prevention,caring of patients on ECMO,caring for patients requiring enteral nutrition,psychological support and nursing management of COVID-19 *** article introduced a useful protocol of donning and doffing personal protective equipment to protect health care workers,and provided key points for the ICU nurses how to take care of COVID-19 patients.

关键词： nurse nursing prevention

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Relationship among Parkinson’s disease, constipation, microbes, and microbiological therapy

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World Journal of Gastroenterology 2024年第3期30卷 225-237页

作者： Xin-Yang yuan Yu-sen Chen Zhou Liu Department of Neurology Affiliated Hospital of Guangdong Medical UniversityZhanjiang 524000Guangdong ProvinceChina Institute of Neurology Guangdong Key Laboratory of Age-Related Cardiac and Cerebral DiseasesZhanjiang 524000Guangdong ProvinceChina

This comprehensive review elucidates the complex interplay between gut microbiota and constipation in Parkinson’s disease(PD),a prevalent non-motor symptom contributing significantly to patients’morbidity.A marked alteration in the gut microbiota,predominantly an increase in the abundance of Proteobacteria and Bacteroidetes,is observed in PD-related *** treatments,although safe,have failed to effectively alleviate symptoms,thereby necessitating the development of novel therapeutic *** interventions such as prebiotics,probiotics,and fecal microbiota transplantation(FMT)hold therapeutic *** prebiotics improve bowel movements,probiotics are effective in enhancing stool consistency and alleviating abdominal *** shows potential for significantly alleviating constipation symptoms by restoring gut microbiota balance in patients with *** promising developments,the causal relationship between changes in gut microbiota and PD-related constipation remains elusive,highlighting the need for further research in this expanding field.

关键词： Parkinson disease Constipation Gut microbiota Prebiotics Probiotics Fecal microbiota transplantation

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Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： yuan Zhao Yidan Zhang Xin Liu Jian Zhang Ya Gao shuyue Li Cui Chang Xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

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Effects of riparian land use on water quality and fish communities in the headwater stream of the Taizi River in China

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Frontiers of Environmental Science & Engineering 2013年第5期7卷 699-708页

作者： sen DING yuan ZHANG Bin LIU Weijing KONG Wei MENG State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental Sciences Beijing 100012 China Laboratory of Riverine Ecological Conservation and Technology Chinese Research Academy of Environmental Sciences Beijing 100012 China

Riparian land use remains one of the most significant impacts on stream ecosystems. This study focuses on the relationship between stream ecosystems and riparian land use in headwater regions. Four riparian land types including forest, grassland, farmland, and residential land were examined to reveal the correlation between stream water and fish communities in headwater streams of the Taizi River in north-eastern China. Four land types along riparian of 3 km in length were evaluated at 25, 50, 100, 200 and 500m widths, respectively. Generally, the results found a significant relationship between riparian land uses and stream water quality. Grassland was positively correlated with water quality parameters （con- ductivity and total dissolved solids） at scales from 100 to 500 m riparian width. Farmland and residential land was negatively correlated with water quality parameters at scales from 25 to 500 m and from 50 to 200 m riparian widths, respectively. Although the riparian forest is important for maintaining habitat diversity and fish communities, the results found that only fish communities were significantly correlated with the proportion of riparian farmland. Farmland had a positive correlation with individual fish abundance within a riparian corridor of 25 to 50 m, but a negative correlation with fish diversity metrics from 25 to 100m. This study indicates that effective riparian management can improve water quality and fish communities in headwater streams.

关键词： fish water quality land use riparian buffer,headwater stream

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Optimization experiment on eccentric lapping of cylindrical rollers

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Nanotechnology and Precision Engineering 2018年第3期1卷 197-204页

作者： Jia Su Julong yuan sen Zhang Binghai Lv Ultra-Precision Machining Research Centre Zhejiang University of Technology

Cylindrical rollers are important elements of bearings,and their machining accuracy and consistency affect the bearing *** a GCr15 cylindrical roller ofФ11×12 as the processing object in this study,the effects of loading pressure,abrasive concentration,and speed combination on cylindrical roller machining precision were investigated using the orthogonal experimental design method on a double-side eccentric pendulum lapping and polishing *** machining parameters of the lapping stage were optimized,and the lapping optimal process parameters were determined by S/N response analysis and analysis of variance(ANOVA).The results show that when the experiment was optimized using loading pressure of 10 N/roller,abrasive concentrationof 20.0 wt%,and rotational speed combination,the material removal rate(MRR)of cylindrical roller reached 0.0896μm/min;the average roughness of the batch decreased from 0.056μm to 0.027μm,51.8%lower than the original batch average roughness,and the deviation decreased from the initial 0.022μm to 0.014μm;the batch average roundness error decreased from 0.47μm to 0.28μm,40.4%lower than the original batch average roundness error,and the deviation decreased from the initial 0.19μm to 0.038μm;and the batch average diameter variation decreased from 4.5μm to about 3.6μm,20%lower than the original batch average diameter *** double-side eccentric lapping of cylinder rollers does not only lead to improvement in the surface quality and shape accuracy of rollers,but also improvement in the batch consistency.

关键词： Cylindrical roller Eccentric pendulum type Orthogonal experiment Lapping Batch consistency

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Review of quantum simulation based on Rydberg many-body system

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Chinese Physics B 2021年第2期30卷 35-44页

作者： Zheng-yuan Zhang Dong-Sheng Ding Bao-sen Shi Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China

Quantum simulation has been developed extensively over the past decades,widely applied to different models to explore dynamics in the quantum *** atoms have strong dipole-dipole interactions and interact with each other over a long distance,which makes it straightforward to build many-body interacting quantum systems to simulate specific ***,neutral atoms are easily manipulated due to their weak *** advantages make Rydberg many-body system an ideal platform to implement quantum *** paper reviews several quantum simulations for different models based on Rydberg many-body systems,including quantum Ising models in one dimension and two dimensions mainly for quantum magnetism,XY model for excitation transport,SSH model for symmetry-protected topological phases,and critical self-organized behaviors in many-body ***,some challenges and promising directions of quantum simulations based on Rydberg many-body system are discussed in this paper.

关键词： many-body quantum simulation Rydberg

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Empirical Entropy for Right Censored Data

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Acta Mathematicae Applicatae Sinica 2015年第2期31卷 395-404页

作者： Guo-qing ZHAO Wei LIANG shu-yuan HE School of Mathematical Sciences Peking University School of Mathematical Sciences Xiamen University School of Mathematical Sciences Capital Normal University

The maximum entropy method has been widely used in many fields, such as statistical mechanics,economics, etc. Its crucial idea is that when we make inference based on partial information, we must use the distribution with maximum entropy subject to whatever is known. In this paper, we investigate the empirical entropy method for right censored data and use simulation to compare the empirical entropy method with the empirical likelihood method. Simulations indicate that the empirical entropy method gives better coverage probability than that of the empirical likelihood method for contaminated and censored lifetime data.

关键词： right censored data empirical entropy

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Empirical Likelihood for AR-ARCH Models Based on LAD Estimation

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Acta Mathematicae Applicatae Sinica 2012年第2期28卷 371-382页

作者： Jin-yu Li Wei Liang shu-yuan He School of Sciences China University of Mining and Technology Xuzhou 221116 China School of Mathematical Sciences Peking University Beijing 100871 China School of Mathematical Sciences Capital Normal University Beijing 100048 China

By employing the empirical likelihood method, confidence regions for the stationary AR（p）-ARCH（q） models are constructed. A self-weighted LAD estimator is proposed under weak moment conditions. An empirical log-likelihood ratio statistic is derived and its asymptotic distribution is obtained. Simulation studies show that the performance of empirical likelihood method is better than that of normal approximation of the LAD estimator in terms of the coverage accuracy, especially for relative small size of observation.

关键词： AR-ARCH model confidence region empirical likelihood LAD estimation

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