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Reconstruction of Allen's type IV fingertip amputation via bilateral unequal-sized hallux osteo-onychocutaneous free flaps:A retrospective study with 5-year follow-up

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Chinese Journal of Traumatology 2024年第6期27卷 403-409页

作者： Xiu-Zhong Li Xiu-Yun Wang Yi-Min Zhou Da-Zhi Yu Hua-Gang Zhang shu-jian hou Ke-Cheng Lao Xiao Fan The 971 Hospital of the People's Liberation Army of China Qingdao266071Shandong provinceChina Qingdao Municipal Hospital Qingdao266011Shandong provinceChina Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine Beijing100007China

Purpose:The reconstruction of Allen''s type IV fingertip amputation is a clinical *** team designed bilateral unequal-sized hallux osteo-onychocutaneous free flaps for the long-term reconstruction of Allen''s type IV fingertip amputation and conducted a retrospective study with a 5-year follow-up aims to evaluate the effects of this ***:A retrospective analysis with a 5-year follow-up including 13 patients with Allen''s type IV fingertip amputation who were admitted to our hospital from January 2010 to January 2017 was *** patients were treated with bilateral unequal-sized hallux osteo-onychocutaneous free *** operation time,intraoperative blood loss,and complications were recorded,and the survival rate of the transplanted flaps was *** the 5-year follow-up after operation,the nail growth time was recorded and the finger appearance was *** the last follow-up appointment,the length,width,and girth of the reconstructed fingertip and contralateral normal fingertip,range of motion of the reconstructed fingertip and contralateral normal fingertip,Semmes-Weinstein test(for the evaluation of tactile sensation),and two-point discrimination testing results were *** 22.0 software was used for the statistical analysis and the data are presented as mean±***:The mean operation time was(5.62±0.51)h,the mean intraoperative blood loss was(34.15±3.13)mL,and the survival rate of the transplanted flaps was 100%.During the 5-year follow-up,the average nail growth time was(10.14±1.98)months and the average bone union time was(3.78±0.91)*** length,width,and girth of the reconstructed fingertip were(31.52±3.73)mm,(17.82±1.74)mm,and(59.75±3.04)mm,respectively,which did not differ from those of the contralateral normal *** range of motion of the reconstructed fingertip was(12.15±2.79)degrees which is different from that of the contralateral normal *** average tactile sensation evaluated

关键词： Fingertip amputation Toenail flap Free transplantation Plastic surgery

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口服或阴道用米索前列醇用于人工流产术前宫口扩张的比较

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中国新药与临床杂志 2003年第12期22卷 726-728页

作者：李洁范书萍侯建香河北省人民医院妇产科河北石家庄050051

目的 :比较在人工流产术前阴道或口服用米索前列醇后宫口扩张的临床效果。方法 :将 16 1例行人工流产术的早孕妇女分成 3组。第 1组 5 3例和第 2组 5 7例于术前 1h分别经阴道用米索前列醇和口服米索前列醇各 4 0 0 μg ,第 3组为对照组... 详细信息

目的 :比较在人工流产术前阴道或口服用米索前列醇后宫口扩张的临床效果。方法 :将 16 1例行人工流产术的早孕妇女分成 3组。第 1组 5 3例和第 2组 5 7例于术前 1h分别经阴道用米索前列醇和口服米索前列醇各 4 0 0 μg ,第 3组为对照组5 1例 ,术前不用任何药物。结果 :第 1组和第 2组宫口扩张有效率分别是 92 % (49/ 5 3)和 89% (5 1/5 7) ,明显高于对照组 0 (0 / 5 1,P 0 .0 5 ) ,但口服用药组不良反应多于阴道用药组。结论 :阴道用米索前列醇组、口服米索前列醇组术中扩宫口作用肯定 ,出血量小、不良反应轻。

关键词：米索前列醇宫缩乏力妊娠初期流产人工投药口服投药阴道内

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Negative PO3-implanted bionic ion transport channels for promoting Li-S battery

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Science China Chemistry 2025年

作者： Wenhuan Huang shun Wang Xuehan hou Yanan Zhang Xingxing Zhang Yaoxiao Zhao Xilang Jin Huabin Zhang Fei Wang jian Zhang Key Laboratory of Chemical Additives for China National Light Industry College of Chemistry and Chemical EngineeringShaanxi University of Science and Technology School of Materials and Chemical Engineering Xi'an Technological University Chemistry Program Physical Science and Engineering Division King Abdullah University of Science and Technology State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences

Lithium-sulfur （Li-S） battery,as a promising next-generation high-energy-density battery,suffers from lithium polysulfides（LPSs） shuttle and Li dendrites *** crystalline framework-based membranes as separator can effectively absorb and restrain LPSs but without precise structural design principal exploration and mechanism ***,bio-inspired 1D oriented lithium-ion transport channels with molecular negatively charged PO3（-1） have been developed in hybrid tetrazole frameworks for promoting the transmission of Li+*** theoretical calculations and in situ spectroscopy demonstrated the higher binding energy and inhibited diffusion of LPSs in *** assembled PP@PO3Janus separator in Li-S coin cell delivered a high initial capacity of 1410.9 mAh g-1at 0.1 C and a low attenuation rate of 0.038%per cycle over 500 cycles at 5 ***,the high capacities of 862,542 and 409 mAh g-1based on high-sulfur-loading cathodes of 2.6,3.8 and 5.0 mg cm-2at0.5 C were achieved,***,the punch battery of PO3@PP separator with S-cathode of 1.2 mg cm-2has been developed for demonstrating its potentials commercial application,which displays impressive capacity of 873.4 mAh g-1with the retention of～78.9%over 50 cycles.

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Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

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Science China Life Sciences 2025年第1期 300-302页

作者： Ze-Min Lin Mai Xiang Wen-Hui Wei shu-Hui Fan Li Chen Jie Wang Xiao-Qian Yang Chun-Hao Yang Shi-Jun He jian-Ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

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Theoretical prediction on corrugated sandwich panels under bending loads

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Acta Mechanica Sinica 2018年第5期34卷 925-935页

作者： Chengfu shu shujuan hou College of Mechanical and Optoelectronics Physics Huaihua UniversityHuaihua 418008China State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China College of Mechanical and Vehicle Engineering Hunan UniversityChangsha 410082China

In this paper,an aluminum corrugated sandwich panel with triangular core under bending loads was ***,the equivalent material parameters of the triangular corrugated core layer,which could be considered as an orthotropic panel,were obtained by using Castigliano's theorem and equivalent homogeneous ***,contributions of the corrugated core layer and two face panels were both considered to compute the equivalent material parameters of the whole structure through the classical lamination theory,and these equivalent material parameters were compared with finite element analysis ***,based on the Mindlin orthotropic plate theory,this study obtain the closed-form solutions of the displacement for a corrugated sandwich panel under bending loads in specified boundary conditions,and parameters study and comparison by the finite element method were executed simultaneously.

关键词： Corrugated sandwich panel Equivalent material parameter Theoretical prediction Bending loads

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Immunotherapeutic strategies targeting B cell maturation antigen in multiple myeloma

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Military Medical Research 2021年第3期8卷 433-443页

作者： Yi Fang jian hou Department of Hematology Renji HospitalSchool of MedicineShanghai Jiao Tong University160 Pujian RoadShanghai 200127China

Multiple myeloma(MM) is the second most common hematologic malignancy, and is characterized by the clonal expansion of malignant plasma cells. Despite the recent improvement in patient outcome due to the use of novel therapeutic agents and stem cell transplantation, all patients eventually relapse due to clone evolution. B cell maturation antigen(BCMA) is highly expressed in and specific for MM cells, and has been implicated in the pathogenesis as well as treatment development for MM. In this review, we will summarize representative anti-BCMA immune therapeutic strategies, including BCMA-targeted vaccines, anti-BCMA antibodies and BCMA-targeted CAR cells. Combination of different immunotherapeutic strategies of targeting BCMA, multi-target immune therapeutic strategies, and adding immune modulatory agents to normalize anti-MM immune system in minimal residual disease(MRD) negative patients, will also be discussed.

关键词： B cell maturation antigen Multiple myeloma Vaccine Antibody CAR T-cells

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Critical thresholds for stage division of water erosion process in different ridge systems in mollisol region of Northeast China

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Journal of Mountain Science 2023年第6期20卷 1540-1560页

作者： JIAO jian QIN Wei LI Kun-heng XU Hai-chao YIN Zhe hou shu-yan State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin China Institute of Water Resources and Hydropower ResearchBeijing 100038China Research Center on Soil and Water Conservation of the Ministry of Water Resources Beijing 100048China School of Soil and Water Conservation Beijing Forestry UniversityBeijing 100083China Heilongjiang Province Hydropower Research Institute Harbin 150070China

Extreme rainfall events on a slope under ridge tillage systems cause concentrated stream soil *** analyse the critical thresholds for different stages of water erosion process of ridge systems,simulated rainfall-erosion experiments for the contour wide ridge(CWR),contour narrow ridge(CNR),longitudinal wide ridge(LWR),and longitudinal narrow ridge(LNR)were conducted under four rainfall intensities,with slope gradients of 3°and 5°.For the runoff event,the runoff depth order was LNR>LWR>CWR>CNR;the soil loss order was CNR>LNR>CWR>*** product of slope factor(S)and rainfall erosivity(R)or runoff depth(D),can be adopted as critical thresholds for different stages of runoff and soil erosion *** the longitudinal ridge systems,R values were provided for LWR and LNR and were the beginning of sheet flow,whereas the product of rainfall erosivity and slope factor(RS)values were provided for LWR and LNR as the beginning of the accelerated concentrated *** the contour ridge systems,R values were provided for CWR and CNR as critical thresholds for the beginning of *** product of runoff depth and slope factor(DS)values were 9.98 and 7.73 mm for CWR and CNR,respectively,and were critical thresholds for the beginning of ridge failure;the DS values were 18.45 and 12.75 mm for CWR and CNR,respectively,and were critical thresholds for the beginning of the formation of ephemeral gully *** critical thresholds can distinguish different stages of soil erosion process modelling.

关键词： Runoff Soil loss Threshold Ridge failure Artificial rainfall simulation

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Number concentration and size distributions of submicron particles in Jinan urban area:Characteristics in summer and winter

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Journal of Environmental Sciences 2007年第12期19卷 1466-1473页

作者： GAO jian WANG Jin CHENG shu-hui XUE Li-kun YAN Huai-zhong hou Lu-jian jianG Yu-quan WANG Wen-xing Environment Research Institute Shandong University Jinan 250100 China Environment Monitoring Station of Jinan Shandong Province Jinan 250014 China Shandong Technical College of Labor and Vocation Shandong Province Jinan 250022 China

The aerosol number concentration and size distribution were measured with the newly developed Wide-range Particle Spectrometer in summer and winter of 2006 at the urban site of Jinan City. Here reported the characteristics of fine particles of the different observation seasons. Relative high number concentrations for the particles in the diameter range of 10-500 nm were observed in both seasons. It was found that the dominant number distributed in particle diameter smaller than 100 nm and the percentage over the number concentration of all air particles is much higher than what has been measured in other urban sites over the world. The number mean diameter in summer was much smaller than in winter, strongly suggesting the different origin of ultrafine particles in different seasons. That is, particles in ultrafine mode mainly came from nucleation and new particle formation in summer while from traffic emission in winter. The diurnal variation also supported this point. Number concentration in the diameter range of 10-200 um got their peak values at noontime, well correlated with the mixing ratio of SO2 and the intensity of solar radiation in summer. While in winter, those in the same diameter range showed the main peaks during the traffic hours happened in the morning and evening.

关键词： number concentration size distribution seasonal variation diurnal variation

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An Analytic Model of Galactic Winds and Mass Outflows

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Chinese Journal of Astronomy and Astrophysics 2005年第4期5卷 327-346页

作者： Cheng-Gang shu hou-Jun Mo shu-De Mao Joint Center for Astrophysics Shanghai Normal University Shanghai 200234 Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 Max-Planck-Institut fuer Astrophysik Karl-Schwarzschild-Strasse 1 Postfach 1317 D-85741 Garching Germany Astronomy Department University of Massachusetts Amherst MA 01003 USA Jodrell Bank Observatory Univ. of Manchester Macclesfield Cheshire SK11 9DL UK

Galactic winds and mass outflows are observed both in nearby starburst galaxies and in high-redshiff star-forming galaxies. We develop a simple analytic model to understand the observed superwind phenomenon with a discussion of the model uncertainties. Our model is built upon the model of McKee ＆ Ostriker for the interstellar medium. It allows one to predict how properties of a superwind,such as wind velocity and mass outflow rate, are related to properties of its starforming host galaxy, such as size, gas density and star formation rate. The model predicts a threshold of star formation rate density for the generation of observable galactic winds. Galaxies with more concentrated star formation activities produce superwinds with higher velocities. The predicted mass outflow rates are comparable to （or slightly larger than） the corresponding star formation rates. We apply our model to both local starburst galaxies and high-redshift Lyman break galaxies,and find its predictions to be in good agreement with current observations. Our model is simple and so can be easily incorporated into numerical simulations and semi-analytical models of galaxy formation.

关键词： galaxies starburst - galaxies ISM - galaxies kinematics and dynamics - galaxies formation and evolution

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Sharp Criterion of Global Existence for Nonlinear Schrodinger Equation with a Harmonic Potential

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Acta Mathematica Sinica,English Series 2009年第4期25卷 537-544页

作者： Ji shu jian ZHANG Sichuan Provincial Key Laboratory of Computer Software Sichuan Normal University Chengdu 610066 P. R. China College of Mathematics and Software Science Sichuan Normal University Chengdu 610066 P. R. China

This paper discusses nonlinear SchrSdinger equation with a harmonic potential. By constructing a different cross-constrained variational problem and the so-called invariant sets, we derive a new threshold for blow-up ... 详细信息

关键词： cross-constrained variational problem nonlinear Schodinger equation global existence,blow-up harmonic potential

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