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Lipid droplets in the nervous system:involvement in cell metabolic homeostasis

Neural Regeneration Research 2025年第3期20卷 740-750页

作者： Yuchen Zhang Yiqing Chen Cheng Zhuang Jingxuan qi Robert Chunhua Zhao Jiao Wang School of Life Sciences Shanghai UniversityShanghaiChina School of Medicine Shanghai UniversityShanghaiChina Institute of Basic Medical Sciences Chinese Academy of Medical Sciences School of Basic MedicinePeking Union Medical CollegeBeijingChina Center of Excellence in Tissue Engineering Chinese Academy of Medical SciencesBeijingChina Beijing Key Laboratory of New Drug Development and Clinical Trial of Stem Cell Therapy BeijingChina

Lipid droplets serve as primary storage organelles for neutral lipids in neurons,glial cells,and other cells in the nervous *** droplet formation begins with the synthesis of neutral lipids in the endoplasmic ***,lipid droplets were recognized for their role in maintaining lipid metabolism and energy homeostasis;however,recent research has shown that lipid droplets are highly adaptive organelles with diverse functions in the nervous *** addition to their role in regulating cell metabolism,lipid droplets play a protective role in various cellular stress ***,lipid droplets exhibit specific functions in neurons and glial *** of lipid droplet formation leads to cellular dysfunction,metabolic abnormalities,and nervous system *** review aims to provide an overview of the role of lipid droplets in the nervous system,covering topics such as biogenesis,cellular specificity,and ***,it will explore the association between lipid droplets and neurodegenerative *** the involvement of lipid droplets in cell metabolic homeostasis related to the nervous system is crucial to determine the underlying causes and in exploring potential therapeutic approaches for these diseases.

关键词： Alzheimer's disease lipid droplet biogenesis lipid droplets lipid metabolism nervous system neurodegenerative disorders oxidative stress Parkinson's disease

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Attitude Coordination of Multi-HUG Formation Based on Multibody System Theory

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China Ocean Engineering 2017年第2期31卷 248-255页

作者： XUE Dong-yang WU Zhi-liang qi Er-mai WANG Yan-hui WANG shu-xin Key Laboratory of Mechanism Theory and Equipment Design of Ministry of Education Tianjin University Tianjin 300072 China School of Mechanical Engineering Tianjin University Tianjin 300072 China National Ocean Technology Center Tianjin 300112 China

Application of multiple hybrid underwater gliders （HUGs） is a promising method for large scale, long-term ocean survey. Attitude coordination has become a requisite for task execution of multi-HUG formation. In this paper, a multibody model is presented for attitude coordination among agents in the HUG formation. The HUG formation is regarded as a multi-rigid body system. The interaction between agents in the formation is described by artificial potential field （APF） approach. Attitude control torque is composed of a conservative torque generated by orientation potential field and a dissipative term related with angular velocity. Dynamic modeling of the multibody system is presented to analyze the dynamic process of the HUG formation. Numerical calculation is carried out to simulate attitude synchronization with two kinds of formation topologies. Results show that attitude synchronization can be fulfilled based on the multibody method described in this paper. It is also indicated that different topologies affect attitude control quality with respect to energy consumption and adjusting time. Low level topology should be adopted during formation control scheme design to achieve a better control effect.

关键词： hybrid underwater gliders (HUGs) formation attitude coordination multibody system Kane's equation

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Metal nanoparticles decorated CoFe-(oxy)hydroxysulfides nanosheets fabricated by a general strategy for electrocatalytic water splitting

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Journal of Energy Chemistry 2025年第1期100卷 26-38页

作者： Xiaodong Yang Haochen Shen Xiaoming Xiao Zhichao Li qi Zhou Wei Yang Bin Jiang Yongli Sun Luhong Zhang Zhenhua Yan School of Chemical Engineering and Technology Tianjin University Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University

This study presents a novel method to fabricate metal-decorated,sulfur-doped layered double hydroxides （M/SLDH） through spontaneous redox and sulfurization *** developed Ag/SLDH and Pt/SLDH catalysts with abundant heterogeneous interfaces and hierarchical nanostructures demonstrated outstanding oxygen evolution reaction （OER） and hydrogen evolution reaction （HER） performance,achieving low overpotentials of 212 and 35 mV at 10 mA cm-2in 1 M KOH,*** both anode and cathode in water splitting,they required only 1.47 V to reach 10 mA cm-2and exhibited high structural robustness,maintaining stability at 1000 mA cm-2for 300 ***-situ Raman analysis revealed that the synergistic effects of metal nanoparticles and S doping significantly promote the transformation into the S-Co1-xFexOOH layer,which serves as the active phase for water ***,ultraviolet photoelectron spectroscopy （UPS） and density functional theory （DFT） analyses indicated that incorporating metal nanoparticles and S doping increase electron density near the Fermi level and reduce reaction energy barriers,thus enhancing intrinsic OER and HER *** study provides a scalable strategy for synthesizing high-performance electrocatalysts for water splitting,with promising potential for broader applications.

关键词： LDH Spontaneous reaction Metal nanoparticles Water splitting

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Review on niobium application in microalloyed steel

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Journal of Iron and Steel Research International 2022年第10期29卷 1513-1525页

作者： Lu-yan Sun Xiang Liu Xi Xu shu-wei Lei hui-gai Li qi-jie Zhai State Key Laboratory of Advanced Special Steel and Shanghai Key Laboratory of Advanced Ferrometallurgy and School of Materials Science and Engineering Shanghai UniversityShanghai200444China Center for Advanced Solidification Technology(CAST) School of Materials Science and EngineeringShanghai UniversityShanghai200444China Ansteel Group Iron and Steel Research Institute AnsteelAnshan114001LiaoningChina

With the rapid development of high-strength low-alloy(HSLA)steel,Nb as an important microalloying element has received more and more attention in recent *** application and behavior of Nb in HSLA steel,including microstructures optimization,refining grain size,and precipitation behavior of Nb-containing phases,were *** could play an important role in following manners:(1)Nb-containing phases promote ferrite formation,and Nb solute promotes bainite formation.(2)Nb solute atoms and Nb-containing phases can inhibit the growth of austenite grains and austenite recrystallization.(3)Nb(C,N)that precipitates in ferrite/bainite can provide more significant strengthening contribution(more than 300 MPa)than that in austenite(about 100 MPa).Some reasonable suggestions for the production of Nb-bearing HSLA steel with excellent mechanical properties were put forward.

关键词： Niobium Precipitate Microalloying High-strength low-alloy steel

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Acute Observational Stimulus of Restrained Mice Induced Anxiolytic Effects in Observer Mice

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Neuroscience Bulletin 2024年第10期40卷 1545-1550页

作者： Chun-hui Jia Fang-qi shu Pak-Ming Lau Hao Wang CAS Key Laboratory of Brain Function and Disease Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230026China Anhui Province Key Laboratory of Biomedical Imaging and Intelligent Processing Institute of Artificial IntelligenceHefei Comprehensive National Science CenterHefei 230088China Interdisciplinary Center for Brain Information The Brain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China National Engineering Laboratory for Brain-inspired Intelligence Technology and Application School of Information Science and TechnologyUniversity of Science and Technology of ChinaHefei 230026China

Dear Editor,Ensuring an appropriate response to external stimuli is essential for animals'survival and *** indicates that such stimuli can affect animals'physiological state and hormone levels,including corticosterone(CORT)[1,2].The impact of these stimuli on animals'performance depends on their density and duration,as they can either facilitate or hinder *** chronic and intense stressors can have detrimental effects on animals'physiological health and behavioral performance,leading to psychiatric disorders such as depression,anxiety,and schizophrenia[3],the effects of acute and mild observational stimuli are still unclear.

关键词： evolution. Observation acute

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Structure and Properties of β-Polypropylene Reinforced by Polypropylene Fiber and Polyamide Fiber

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Chinese Journal of Polymer Science 2014年第4期32卷 509-518页

作者： qi Liu hui-hui Li 闫寿科 State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology

Matrix/fiber composites of,β-form isotactic polypropylene （iPP） matrix and α-iPP or PA6 fibers were prepared by laminating technique under different preparation temperatures. The mechanical properties and interracial morphologies of these composites were studied by tensile test, optical microscopy and scanning electron microscopy, respectively. The experimental results show that the tensile yield load and tensile modulus of β-iPP/PA6 matrix/fiber systems increased significantly at the expense of elongation at break. These mechanical properties show essentially no dependence on the sample preparation temperature. On the other hand, the mechanical properties of iPP matrix/fiber single polymer composites depend strongly on the sample preparation temperature. At low sample preparation temperature, e.g., 172 ℃, the solid cr-iPP fiber induces tr-iPP crystallization, leading to the formation of a-iPP transcrystalline layer around the fiber. This results in a remarkable increment of the tensile yield load and tensile modulus. The elongation at break is also much better than that of the iPP/PA6 matrix/fiber system. It reflects a better interracial adhesion of the single polymer composite compared with the iPP/PA6 composite. At higher sample preparation temperature, e.g., 174 ℃ or 176 ℃, the partial surface melting of the oriented fiber allows interdiffusion of iPP molecular chains in the molten fiber and matrix melt. The penetration of matrix chains into the molten iPP fiber results in some iPP molecular chains being included partially in the recrystallized fiber and the induced β-transcrystalline layers. This kind of configuration leads to an improvement of interfacial adhesion between the fiber and matrix, which causes a simultaneous increase of the tensile yield load, tensile modulus and elongation at break of β-iPP.

关键词： Polypropylene Composite Mechanical property Interfacial morphology.

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CO_(2) electrolysis to formic acid for carbon neutralization

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Green Energy & Environment 2024年第9期9卷 1333-1335页

作者： Kezhen qi shu-yuan Liu Yingjie Zhang hui Zhang Vadim Popkov Oksana Almjasheva College of Pharmacy Dali UniversityDali671000China College of Agriculture and Biological Science Dali UniversityDali671000China School of Arts Minnan Normal UniversityZhangzhou363000China Hydrogen Energy Laboratory Ioffe InstituteSaint Petersburg194021Russia Department of Physical Chemistry Saint Petersburg Electrotechnical University“LETI”Saint Petersburg197022Russia

To avoid carbonate precipitation for CO_(2) electrolysis,developing CO_(2) conversion in an acid electrolyte is viewed as an ultimately challenging *** Nature,Xia et *** explored a proton-exchange membrane system for reducing CO_(2) to formic acid with a Pb±Pb SO_(4) composite catalyst derived from waste lead-acid batteries based on the lattice carbon activation *** to 93%Faradaic efficiency was realized when formic acid was produced by this technology.

关键词： CO_(2) electrolysis Proton-exchange membrane system Faradaic efficiency Carbon neutralization CO_(2) reduction reaction

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Modelling the annual cycle of landfast ice near Zhongshan Station,East Antarctica

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Acta Oceanologica Sinica 2021年第7期40卷 129-141页

作者： Jiechen Zhao Tao Yang qi shu hui Shen Zhongxiang Tian Guanghua Hao Biao Zhao Key Laboratory of Marine Hazards Forecasting National Marine Environmental Forecasting CenterMinistry of Natural ResourcesBeijing 100081China Laboratory for Regional Oceanography and Numerical Modeling Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China 92682 Unit Zhanjiang 524001China First Institute of Oceanography Ministry of Natural ResourcesQingdao 266061China

A high resolution one-dimensional thermodynamic snow and ice(HIGHTSI)model was used to model the annual cycle of landfast ice mass and heat balance near Zhongshan Station,East *** model was forced and initialized by meteorological and sea ice in situ observations from April 2015 to April *** produced a reasonable snow and ice evolution in the validation experiments,with a negligible mean ice thickness bias of(0.003±0.06)m compared to in situ *** further examine the impact of different snow conditions on annual evolution of first-year ice(FYI),four sensitivity experiments with different precipitation schemes(0,half,normal,and double)were *** results showed that compared to the snow-free case,the insulation effect of snow cover decreased bottom freezing in the winter,leading to 15%–26%reduction of maximum ice *** snow cover caused negative freeboard and flooding,and then snow ice formation,which contributed 12%–49%to the maximum ice *** early summer,snow cover delayed the onset of ice melting for about one month,while the melting of snow cover led to the formation of superimposed ice,accounting for 5%–10%of the ice *** ice melting was a significant contributor in summer whether snow cover existed or not,accounting for 35%–56%of the total summer ice *** multi-year ice(MYI)simulations suggested that when snow-covered ice persisted from FYI to the 10th MYI,winter congelation ice percentage decreased from 80%to 44%(snow ice and superimposed ice increased),while the contribution of internal ice melting in the summer decreased from 45%to 5%(bottom ice melting dominated).

关键词： landfast ice annual cycle snow influence Zhongshan Station East Antarctica

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An online electricity cost budgeting algorithm for maximizing green energy usage across data centers

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Frontiers of Computer Science 2017年第4期11卷 661-674页

作者： hui DOU Yong qi School of Electronic and Information Engineering Xi'an Jiaotong University Xi'an 710049 China

With the sky-rocketing development of Internet services, the power usage in data centers has been signifi- cantly increasing. This ever increasing energy consumption leads to negative environmental impact such as global warming. To reduce their carbon footprints, large Internet service operators begin to utilize green energy. Since green energy is currently more expensive than the traditional brown one, it is important for the operators to maximize the green en- ergy usage subject to their desired long-term （e.g., a month） cost budget constraint. In this paper, we propose an online algorithm GreenBudget based on the Lyapunov optimization framework. We prove that our algorithm is able to achieve a delicate tradeoff between the green energy usage and the en- forcement of the cost budget constraint, and a control parameter V is the knob to arbitrarily tune such a tradeoff. We evaluate GreenBudget utilizing real-life traces of user requests, cooling efficiency, electricity price and green energy avail- ability. Experimental results demonstrate that under the same cost budget constraint, GreenBudget can increase the green energy usage by 11.55% compared with the state-of-the-art work, without incurring any performance violation of user requests.

关键词： electricity cost budgeting green energy coolingefficiency data center Lyapunov optimization

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Effects of yttrium and zirconium additions on inclusions and mechanical properties of a reduced activation ferritic/martensitic steel

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Journal of Iron and Steel Research International 2020年第2期27卷 197-207页

作者： Dong-ping Zhan Guo-xing qiu Chang-sheng Li Min qi Zhou-hua Jiang hui-shu Zhang School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina State Key Laboratory of Rolling and Automation.Northeastern University Shenyang 110819LiaoningChina School of Metallurgy Engineering Liaoning Institute of Science and TechnologyBenxi 117004.LiaoningChina

The effects of two alloying elements,i.e.,yttrium(Y)and zirconium(Zr),on the inclusion,microstructure,tensile property and impact toughness of reduced activation ferritic/martensitic(RAFM)steel are *** size and number of particles were determined by optical microscopy,and the particle types were examined by scanning electron *** size of?20% and?85% of the inclusions lied in the range of 0.5-1.0μm and 0.5-3.0μm,*** Y-and Y-Zr-containing specimens,the density of the fine inclusions,with a size less than 0.5μm,was found to be 1.06×10^17 and 9.82×10^16 m^-*** specimens were normalized at 1323 K for 30 min and tempered at 923 and 1023 K for 90 min,resulting in the formation of tempered martensite with M23C6 carbides and MX ***-containing RAFM steel tempered at 923 K formed M23C6 carbides and nano-sized carbides with Zr,conferring superior strength balance and impact *** yield strength of alloy reached 695 MPa,and a low ductile-brittle transition temperature of 238 K was maintained.

关键词： 9Cr oxide-dispersion-strengthened steel Inclusion Mechanical property DBTT Yttrium Zirconium

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