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Career Map: visualizing career trajectory

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Science China(Information Sciences) 2018年第10期61卷 247-249页

作者： kan WU Jie TANG Zhou SHAO Xinyi XU Bo GAO shu ZHAO Department of Computer Science and Technology Tsinghua University School of Computer Science and Engineering Nanjing University of Science and Technology International School Beijing University of Posts and Telecommunications School of Computer Science and Technology Anhui University

This study introduces a system named Career Map that visualizes a scholar’s career trajectory. As an online demonstration of Career Map, we have shown the visualization result by Career Map for the AMiner 2016 most influential scholars in machine learning (ML)1). Each trajectory path on the map represents the movement of a scholar between different places (affiliations). The heatmap reveals the geographic distribution of the most influential ML scholars; a larger hotspot means a larger immigration of scholars into an affiliation. The right sidebar is a list of all scholars. When the user selects (clicks on) a scholar, the trajectory path of

关键词： Career Map visualizing career trajectory Figure

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妊娠期高血压疾病的危险因素分析

中国基层医药 2008年第4期15卷 637-638页

作者：阚淑娟赵永燕陈永利张素娟唐山市妇幼保健医院内科河北省唐山063000

目的探讨妊娠期高血压疾病的危险因素。方法对95例妊娠期高血压疾病进行问卷调查，内容涉及患者的一般情况及临床既往史。结果妊娠期高血压冬季发病48例（50．5％），35岁以上发生60例（63．2％），血型为A型者40例（42．1％），高中以... 详细信息

目的探讨妊娠期高血压疾病的危险因素。方法对95例妊娠期高血压疾病进行问卷调查，内容涉及患者的一般情况及临床既往史。结果妊娠期高血压冬季发病48例（50．5％），35岁以上发生60例（63．2％），血型为A型者40例（42．1％），高中以下文化程度者62例（65．3％），营养状况不良者55例（57．9％），有家族高血压病史者30例（31．6％），本人有高血压病史者26例（27．4％），糖尿病史者18例（18．9％），孕后糖尿病史者15例（15．8％）。结论年龄、血型、文化程度、营养状况、家族高血压病史、本人高血压病史、糖尿病史等是妊娠期高血压疾病发生的危险因素。

关键词：高血压妊娠性危险因素

依达拉奉右莰醇用于不同程度急性脑梗死治疗的疗效研究

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徐州医科大学学报 2023年第8期43卷 609-612页

作者：林小千阚姝张瑞成耿德勤丁红梅徐州医科大学附属医院神经内科江苏徐州221002

目的探讨依达拉奉右莰醇治疗不同程度急性脑梗死的临床疗效。方法纳入2021年1月至2021年12月徐州医科大学附属医院神经内科急性脑梗死患者180例为研究对象,随机分为2组,分别为对照组和观察组(依达拉奉右莰醇)各90例。比较2组治疗前后的... 详细信息

目的探讨依达拉奉右莰醇治疗不同程度急性脑梗死的临床疗效。方法纳入2021年1月至2021年12月徐州医科大学附属医院神经内科急性脑梗死患者180例为研究对象,随机分为2组,分别为对照组和观察组(依达拉奉右莰醇)各90例。比较2组治疗前后的血清炎性因子、神经功能缺损评分。通过美国国立卫生院神经功能缺损量表(NIHSS)评分将急性脑梗死患者细分为轻型(NIHSS≤5分)和中-重型(NIHSS>5分)2种亚型,再比较不同程度脑梗死患者的2种治疗方法的临床疗效。结果治疗前2组患者基线资料差异无统计学意义(P>0.05)。治疗后,2组的炎症因子及NIHSS评分均下降(P<0.05);与对照组相比,观察组的NIHSS评分和炎性因子水平明显降低(P<0.05)。观察组中,与轻型亚组相比,中-重型亚组的炎性因子和NIHSS更低(P<0.05)。结论依达拉奉右莰醇通过降低炎性因子改善急性脑梗死的神经功能缺损症状,并且对中-重型急性脑梗死症状改善效果更好。

关键词：急性脑梗死依达拉奉右莰醇炎性因子神经功能缺损神经保护临床疗效

Specific effects of c-Jun NH2-terminal kinaseinteracting protein 1 in neuronal axons

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Neural Regeneration Research 2016年第1期11卷 114-118页

作者： shu Tang Qiang Wen Xiao-jian Zhang Quan-cheng kan Department of Pharmacy the First Affiliated Hospital of Zhengzhou University Department of Clinical Pharmacology Basic Medical College Zhengzhou University

c-Jun NH2-terminal kinase（JNK）-interacting protein 3 plays an important role in brain-derived neurotrophic factor/tropomyosin-related kinase B（Trk B） anterograde axonal transport. It remains unclear whether JNK-interacting protein 1 mediates similar effects, or whether JNK-interacting protein 1 affects the regulation of Trk B anterograde axonal transport. In this study, we isolated rat embryonic hippocampus and cultured hippocampal neurons in vitro. Coimmunoprecipitation results demonstrated that JNK-interacting protein 1 formed Trk B complexes in vitro and in vivo. Immunocytochemistry results showed that when JNK-interacting protein 1 was highly expressed, the distribution of Trk B gradually increased in axon terminals. However, the distribution of Trk B reduced in axon terminals after knocking out JNK-interacting protein 1. In addition, there were differences in distribution of Trk B after JNK-interacting protein 1 was knocked out compared with not. However, knockout of JNK-interacting protein 1 did not affect the distribution of Trk B in dendrites. These findings confirm that JNK-interacting protein 1 can interact with Trk B in neuronal cells, and can regulate the transport of Trk B in axons, but not in dendrites.

关键词： nerve regeneration c-Jun NH2-terminal kinase-interacting protein neurons brain-derived neurotrophic factor tropomyosin-related kinase B axons hippocampus dendrites regulation neural regeneration

Growth behavior of electroless copper on silicon substrate

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International Journal of Minerals,Metallurgy and Materials 2007年第1期14卷 67-71页

作者： Shin-Shyan Wu Ting-kan Tsai shu-Huei Hsieh Wen-Jauh Chen Institute of Electro-Optical and Materials Science Formosa University Department of Materials Science and Engineering Formosa University Graduate Institute of Materials Engineering Pingtung University of Science and Technology

The growth behavior containing deposit morphology, growth rate, activation energy, and growth mechanism of copper on silicon substrate, especially at the initial stage, in the electroless plating process was studied. Copper was deposited on the surface of the silicon substrate in an electroless plating bath containing formalin (CH2O 37vol%) as a reducing agent at a pH value of 12.5 and a tem- perature of 50-75°C. The copper deposit was characterized using a field emission scanning electron microscope and transmission elec- tron microscope. The results showed that after the activation process, nanoscale Pd particles were distributed evenly on the surface of the silicon; in the deposition process, copper first nucleated at locations not only near the Pd particles but also between the Pd particles; the growth rate of electroless Cu ranged from 0.517 nm/s at 50°C to 1.929 nm/s at 75°C. The activation energy of electroless Cu on Si was 52.97 kJ/mol.

关键词： electroless copper silicon substrate activation energy growth mechanism

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数字孪生曹娥江流域试点建设实践与探索

水利信息化 2024年第3期 18-22,36页

作者：盛志刚舒全英徐侃王青青绍兴市镜岭水库建设运行中心浙江绍兴312000 浙江省水利水电勘测设计院有限责任公司浙江杭州310002 绍兴市水利局浙江绍兴312000

在水利部数字孪生流域建设和浙江省数字化改革的背景下,针对曹娥江流域预报调度一体化、风险隐患闭环管控、流域防洪减灾共同治理的需求和痛点,进行数字孪生曹娥江流域试点建设实践与探索。按照数字孪生曹娥江流域建设的总体架构,通过构... 详细信息

在水利部数字孪生流域建设和浙江省数字化改革的背景下,针对曹娥江流域预报调度一体化、风险隐患闭环管控、流域防洪减灾共同治理的需求和痛点,进行数字孪生曹娥江流域试点建设实践与探索。按照数字孪生曹娥江流域建设的总体架构,通过构建L2和L3级数据底板,全过程耦合、水库群优化调度智能决策等模型的数字孪生流域关键技术,打造曹娥江智慧防洪应用,实现预报、预警、预演、预案“四预”场景构建,“三图一清单”在线分析,以及3种调度模式灵活应用。研究成果能够推进流域防洪核心业务流程重塑,实现防汛全链条一体化融合,并在2022年“轩岚诺”和“梅花”台风防御过程中投入实战应用,取得一定成效,可为数字孪生流域防洪应用建设提供技术示范和经验借鉴。

关键词：数字孪生流域数据底板模型算法流域防洪曹娥江流域

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在线固相萃取-液相法测定食品中胡萝卜素

中国食物与营养 2024年第4期30卷 49-52页

作者：俞淑庞贝妮林毅侃上海市质量监督检验技术研究院国家食品质量监督检验中心/国家市场监管重点试验室(乳及乳制品检测与监控技术) 上海200233

目的:采用两泵一阀的在线固相萃取-高效液相色谱技术建立一种能够快速检测食品中胡萝卜素的方法,避免了胡萝卜素在复杂前处理过程中的损失。方法:在线固相萃取柱PLRP-S(2.1 mm×12.5 mm)液相分离色谱柱PAH(2.1 mm×100 mm,1.8μm);固相... 详细信息

目的:采用两泵一阀的在线固相萃取-高效液相色谱技术建立一种能够快速检测食品中胡萝卜素的方法,避免了胡萝卜素在复杂前处理过程中的损失。方法:在线固相萃取柱PLRP-S(2.1 mm×12.5 mm)液相分离色谱柱PAH(2.1 mm×100 mm,1.8μm);固相萃取泵流动相,水+甲醇,液相分离流动相,甲醇+二氯甲烷;检测波长450 nm。结果:该方法在0.10~2.00μg/mL保持良好的线性,方法的检出限和定量限均能够满足检测需求。α-胡萝卜素回收率为92.0%~105.4%,β-胡萝卜素回收率91.1%~107.2%。结论:该方法利用两泵一阀的在线固相萃取技术,能高效、快速检测食品中胡萝卜素,检测效率高,前处理提取效率好,方法能够满足检测需要。

关键词：在线固相萃取高效液相色谱胡萝卜素食品

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Full-Scale Numerical Simulation of the Local Scour Under Combined Current and Wave Conditions Based on Field Data

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China Ocean Engineering 2023年第6期37卷 1032-1043页

作者： SUI shu-huan ZHAO Xue-liang CHEN Xin-rui DENG Wen-ni SHEN kan-min School of Civil Engineering Southeast UniversityNanjing 211100China Key Laboratory of Concrete and Prestressed Concrete Structure of Ministry of Education Southeast UniversityNanjing 211100China PowerChina Huadong Engineering Corporation Limited Hangzhou 311122China

The monopile is the most common foundation to support offshore wind *** the marine environment,local scour due to combined currents and waves is a significant issue that must be considered in the design of wind turbine *** this paper,a full-scale numerical model was developed and validated based on field data from Rudong,*** scour development around monopiles was investigated,and the effects of waves and the Reynolds number Re were *** formulas for predicting the scour depth in the literature have been *** is found that waves can accelerate scour development even if the KC number is small(0.78

关键词： full-scale numerical simulation field data scale effect Reynolds number effects local scour

奥卡西平对妊娠小鼠的不良影响及叶酸的干预作用

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江苏大学学报（医学版） 2011年第2期21卷 113-116页

作者：阚淑娟郑丽娜李云霞杨建春唐山市妇幼保健医院儿内科河北唐山063000

目的:观察抗癫痫药物奥卡西平对妊娠小鼠的不良作用,探讨叶酸对其不良效应的干预效果。方法:将100只雌性和50只雄性小鼠随机分为5组(雌雄比例2∶1),分别为①空白对照组(灌胃蒸馏水,10 ml/kg);②奥卡西平单次剂量组(150 mg/kg);③奥卡西... 详细信息

目的:观察抗癫痫药物奥卡西平对妊娠小鼠的不良作用,探讨叶酸对其不良效应的干预效果。方法:将100只雌性和50只雄性小鼠随机分为5组(雌雄比例2∶1),分别为①空白对照组(灌胃蒸馏水,10 ml/kg);②奥卡西平单次剂量组(150 mg/kg);③奥卡西平二次给药组(上、下午各为75 mg/kg);④奥卡西平单次剂量联合叶酸组(150mg/kg+0.07 mg/kg);⑤奥卡西平二次给药联合叶酸组(75 mg/kg+0.035 mg/kg)。观察小鼠是否受孕、流产、畸形、死胎、每窝仔鼠的数目及孕期增重情况等指标。结果:①单次剂量组小鼠的受孕率下降,孕鼠的流产率、死胎率和畸胎率均上升,孕期增重和每窝正常仔鼠数目减少(P<0.05)。②与二次给药组和二次给药联合叶酸组相比,单次剂量组和单次剂量联合叶酸组小鼠的受孕率下降、死胎率上升(P<0.05);③与单次剂量联合叶酸组和二次给药联合叶酸组相比,单次剂量组和二次给药组小鼠的受孕率下降、死胎率上升、孕期增重减少(P<0.05)。结论:奥卡西平可导致妊娠小鼠妊娠意外的增多,小剂量多次给药以及补充叶酸可降低奥卡西平的不良作用。

关键词：妊娠抗癫痫药物叶酸死胎畸胎增重