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Rapid Phase Ambiguity Elimination Methods for DOA Estimator via Hybrid Massive MIMO Receive Array

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Chinese Journal of Electronics 2024年第1期33卷 175-184页

作者： Xichao zhan.Zhongwen SUN Feng shu Yiwen CHEN Xin CHENG Yuanyuan WU Qi zhan. Yifan LI Peng zhan. School of Information and Communication Engineering Hainan University School of Electronic and Optical Engineering Nanjing University of Science and Technology

For a sub-connected hybrid multiple-input multiple-output(MIMO) receiver with K subarrays and N antennas, there exists a challenging problem of how to rapidly remove phase ambiguity in only single time-slot. A direction of arrival(DOA) estimator of maximizing received power(Max-RP) is proposed to find the maximum value of K-subarray output powers, where each subarray is in charge of one sector, and the center angle of the sector corresponding to the maximum output is the estimated true DOA. To make an enhancement on precision, Max-RP plus quadratic interpolation(Max-RP-QI) method is designed. In the proposed Max-RP-QI, a quadratic interpolation scheme is adopted to interpolate the three DOA values corresponding to the largest three receive powers of *** achieve the Cramer Rao lower bound, a Root-MUSIC plus Max-RP-QI scheme is developed. Simulation results show that the proposed three methods eliminate the phase ambiguity during one time-slot and also show low computational complexities. The proposed Root-MUSIC plus Max-RP-QI scheme can reach the Cramer Rao lower bound,and the proposed Max-RP and Max-RP-QI are still some performance losses 2–4 d B compared to the Cramer Rao lower bound.

关键词： Phased arrays Interpolation Wireless sensor networks Direction-of-arrival estimation Simulation Receiving antennas Massive MIMO

Prediction and analysis of albumin-bilirubin score combined with liver function index and carcinoembryonic antigen on liver metastasis of colorectal cancer

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1670-1680页

作者： zhan.Mei Wang shu-Ping Pan Jing-Jing zhan. Jun Zhou Department of Medical Oncology Qilu Hospital(Qingdao)Cheeloo College MedicineShandong UniversityQingdao 266000Shandong ProvinceChina Department of Gastroenterology Feicheng People’s HospitalFeicheng 271600Shandong ProvinceChina Department of Anus and Intestine Surgery Xiangya Hospital of Central South UniversityChangsha 410008Hunan ProvinceChina Department of Oncology Qilu Hospital(Qingdao)Cheeloo College MedicineShandong UniversityQingdao 266000Shandong ProvinceChina

BACKGROUND Colorectal cancer(CRC)is a common malignant tumor,and liver metastasis is one of the main recurrence and metastasis modes that seriously affect patients’survival rate and quality of *** such as albumin bilirubin(ALBI)score,liver function index,and carcinoembryonic antigen(CEA)have shown some potential in the prediction of liver metastasis but have not been fully *** To evaluate its predictive value for liver metastasis of CRC by conducting the combined analysis of ALBI,liver function index,and CEA,and to provide a more accurate liver metastasis risk assessment tool for clinical treatment *** This study retrospectively analyzed the clinical data of patients with CRC who received surgical treatment in our hospital from January 2018 to July 2023 and were followed up for 24 *** to the follow-up results,the enrolled patients were divided into a liver metastasis group and a nonliver metastasis group and randomly divided into a modeling group and a verification group at a ratio of 2:*** risk factors for liver metastasis in patients with CRC were analyzed,a prediction model was constructed by least absolute shrinkage and selection operator(LASSO)logistic regression,internal validation was performed by the bootstrap method,the reliability of the prediction model was evaluated by subject-work characteristic curves,calibration curves,and clinical decision curves,and a column graph was drawn to show the prediction *** Of 130 patients were enrolled in the modeling group and 65 patients were enrolled in the verification group out of the 195 patients with CRC who fulfilled the inclusion and exclusion *** LASSO regression variable screening and logistic regression *** ALBI score,alanine aminotransferase(ALT),and CEA were found to be independent predictors of liver metastases in CRC patients[odds ratio(OR)=8.062,95%confidence interval(CI):2.545-25.540],(OR=1.037,95%CI:1.004-1.071)and(OR=1.0

关键词： Albumin-bilirubin Carcinoembryonic antigen Colorectal cancer Tumor metastasis Prediction model

Facile construction of Mxene-supported niobium hydride nanoparticles toward reversible hydrogen storage in magnesium borohydride

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Rare Metals 2024年第9期43卷 4387-4400页

作者： Ao Xia Jia-Guang Zheng Qing-Bo zhan. Yu-Gang shu Cheng-Guo Yan Liu-Ting zhan. zhan.Liang Tao Li-Xin Chen School of Energy and Power Jiangsu University of Science and Technology Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai University State Key Laboratory of Silicon and Advanced Semiconductor Materials School of Materials Science and EngineeringZhejiang University

The facile construction of nanoscale NbHxsupported by Ti3C2（NbHx@Ti3C2） was achieved using facile ball milling strategy to improve the hydrogen desorption kinetics and reversibility of magnesium borohydride (Mg（BH4）2).The doping of 30 wt%NbHx@Ti3C2catalyst reduced the onset dehydrogenation temperature of Mg（BH4）2to 71.2℃.Additionally,the Mg（BH4）2+30NbHx@Ti3C2composite achieved remarkable hydrogen release of over 9.2 wt% at a temperature as low as 230℃,indicating unexpected dehydrogenation ***,the reversibility of NbHx@Ti3C2doped Mg（BH4）2was retained to more than 4.2 wt%after four cycles,which was increased by 68% compared to that of undoped Mg（BH4）*** strong catalysis of NbHx@Ti3C2catalyst could be attributed to the synergistic effect of NbHxand Ti3C2in hydrogen spillover and *** as a??hydrogen pump??for effective hydrogen spillover,while Ti3C2created numerous diffusion channels for hydrogen dissolution and provided the active catalytic site to facilitate the re/dehydrogenation of Mg（BH4）2.

关键词： Catalysts Hydrogen storage Magnesium borohydride Mxene

Acid mine drainage activation mechanism on lime-depressed pyrite flotation from copper sulfide ore

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Transactions of Nonferrous Metals Society of China 2024年第9期34卷 2987-3001页

作者： Jia-qiao YUAN zhan.DING Yun-xiao BI Jie LI shu-ming WEN Shao-jun BAI Faculty of Land Resource Engineering Kunming University of Science and TechnologyKunming 650093China State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Kunming University of Science and TechnologyKunming 650093China Yunnan Key Laboratory of Green Separation and Enrichment of Strategic Mineral Resources Kunming University of Science and TechnologyKunming 650093China

The lime-depressed pyrite from Cu differential flotation tailings with acid mine drainage(AMD)as a natural activator was *** effect of AMD on lime-depressed pyrite flotation was investigated by a series of laboratory flotation tests and surface analytical *** test results indicated that AMD could effectively activate the pyrite flotation with a sodium butyl xanthate(SBX)collector,and a high-quality sulfur concentrate was *** ion concentration analysis results indicated that AMD facilitated desorption of Ca~(2+)and adsorption of Cu~(2+)on the depressed-pyrite *** measurements and contact angle analysis results confirmed that adding AMD improved the adsorption amount of SBX collector on the pyrite surface and increased the contact angle by 31°.Results of Raman spectroscopy and X-ray photoelectron spectroscopy analysis indicated that AMD treatment promoted the formation of hydrophobic species(S~0 hydrophobic entity and copper sulfides)and the removal of hydrophilic calcium and iron species on the pyrite surface,which reinforced the adsorption of *** findings of the present research provide important theoretical basis and technical support for a cleaner production of copper sulfide ores.

关键词： copper sulfur ore acid mine drainage lime-depressed pyrite flotation natural activator activation mechanism

Thin-walled and large-sized magnesium alloy die castings for passenger car cockpit:Application,materials,and manufacture

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China Foundry 2024年第5期21卷 525-545页

作者： Lei zhan.Yu-meng Sun Yang Song Chun-hua Kong Kai Ma Bai-xin Dong Hong-yu Yang Shi-li shu Feng Qiu School of Automotive Engineering Jilin Communication PolytechnicChangchun 130012China Key Laboratory of Automobile Materials of Ministry of Education School of Materials Science and EngineeringNanling CampusJilin UniversityChangchun 130025China

In order to effectively reduce energy consumption and increase range mile,new energy vehicles represented by Tesla have greatly aroused the application of integrated magnesium(Mg)alloy die casting technology in ***,the application of Mg alloys in automobiles,especially in automotive cockpit components,is quite extensive,while it has almost disappeared for a period of time due to its relatively high cost,causing a certain degree of information loss in the application technology of Mg alloy parts in *** rapid development of automotive technology has led to a higher requirement for the automotive components compared with those traditional ***,whatever the components themselves,or the Mg alloy materials and die casting process have to face an increasing challenge,needing to be *** addition,owing to its high integration characteristics,the application of Mg alloy die casting technology in large-sized and thin-walled automotive parts has inherent advantages and needs to be expanded ***,it necessitates exploring advance Mg alloys and new product structures and optimizing die casting *** article summarizes and analyzes the development status of thin-walled and large-sized die casting Mg alloy parts in passenger car cockpit and corresponding material selection methods,die casting processes as well as mold design ***,this work will aid researchers in establishing a comprehensive understanding of the manufacture of thin-walled and large-sized die casting Mg alloy parts in automobile *** will also assist them in developing new Mg alloys with improved comprehensive performance and new processes to meet the high requirements for die casting automotive components.

关键词： Mg alloys thin wall large size automotive part die casting

Androgen signaling inhibits de novo lipogenesis to alleviate lipid deposition in zebrafish

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Zoological Research 2024年第2期45卷 355-366页

作者： Jing-Yi Jia Guang-Hui Chen Ting-Ting shu Qi-Yong Lou Xia Jin Jiang-Yan He Wu-Han Xiao Gang Zhai zhan.Yin College of Fisheries Huazhong Agriculture UniversityWuhanHubei 430070China State Key Laboratory of Freshwater Ecology and Biotechnology Institute of HydrobiologyChinese Academy of SciencesWuhanHubei 430072China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China Hubei Key Laboratory of Three Gorges Project for Conservation of Fishes Chinese Sturgeon Research InstituteChina Three Gorges CorporationYichangHubei 443100China Hubei Hongshan Laboratory Huazhong Agriculture UniversityWuhanHubei 430070China Innovative Academy of Seed Design Chinese Academy of SciencesBeijing 100049China

Testosterone is closely associated with lipid metabolism and known to affect body fat composition and muscle mass in ***,the mechanisms by which testosterone acts on lipid metabolism are not yet fully understood,especially in *** this study,cyp17a1-/-zebrafish(Danio rerio)exhibited excessive visceral adipose tissue(VAT),lipid content,and up-regulated expression and activity of hepatic de novo lipogenesis(DNL)*** assay for transposase accessible chromatinwithsequencing(ATAC-seq)results demonstrated that chromatin accessibility of DNL genes was increased in cyp17a1-/-fish compared to cyp17a1+/+male fish,including stearoyl-CoA desaturase(scd)and fatty acid synthase(fasn).Androgen response element(ARE)motifs in the androgen signaling pathway were significantly enriched in cyp17a1+/+male fish but not in cyp17a1-/-*** androgen receptor(ar)-/-and wildtype(WT)zebrafish administered with Ar antagonist flutamide displayed excessive visceral adipose tissue,lipid content,and up-regulated expression and activity of hepatic de novo lipogenesis *** Ar agonist BMS-564929 reduced the content of VAT and lipid content,and down-regulated acetyl-CoA carboxylase a(acaca),fasn,and scd ***,the rescue effect of testosterone on cyp17a1-/-fish in terms of phenotypes was abolished when ar was additionally ***,these findings reveal that testosterone inhibits lipid deposition by down-regulating DNL genes via Ar in zebrafish,thus expanding our understanding of the relationship between testosterone and lipid metabolism in teleosts.

关键词： Cyp17a1 Testosterone Androgen receptor De novo lipogenesis Fatty acid synthesis

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Experimental investigation of vibration pretreatment-microwave curing process for carbon fiber reinforced resin matrix composites

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Journal of Central South University 2024年第6期31卷 1838-1855页

作者： zhan. De-chao zhan.Li-hua MA Bo-lin YAO shun-ming GUO Jin-zhan.GUAN Cheng-long LIU shu Light Alloys Research Institute Central South UniversityChangsha 410083China College of Mechanical and Electrical Engineering Central South UniversityChangsha 410083China School of Mechanical Engineering and Automation Fuzhou UniversityFuzhou 350108China

The vibration pretreatment-microwave curing process is an efficient,low energy consumption,and high-quality out-of-autoclave curing process for carbon fiber resin matrix *** study aims to investigate the impact of vibration pretreatment temperature on the fiber weight content,microscopic morphology and mechanical properties of the composite laminates by using optical digital microscopy,universal tensile testing machine and thermo-gravimetric ***,the combined mode of Bragg fiber grating sensor and temperature measurement fiber was employed to explore the effect of vibration pretreatment on the strain process during microwave *** study results revealed that the change in vibration pretreatment temperature had a slight impact on the fiber weight content when the vibration acceleration remained *** metallographic and interlaminar strength of the specimen formed at a vibration pretreatment temperature of 80℃ demonstrated a porosity of 0.414% and a 10.69% decrease in interlaminar shear strength compared to autoclave ***,the introduction of the vibration energy field during the microwave curing process led to a significant reduction in residual strain in both the 0°and 90°fiber directions,when the laminate was cooled to 60℃.

关键词： vibration microwave curing porosity interlaminar shear strength thermo-gravimetric analysis curing strain

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In vivo study of the effect of anlotinib on the stemness of the lenvatinib-resistant hepatocellular carcinoma cells and the underlying mechanisms

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Oncology and Translational Medicine 2024年第1期10卷 4-12页

作者： Jing zhan.shu Huang Bai Wei Zao-Zao Huang Sheng-Li Yang Division of Oncology Tianyou Hospital Affiliated to Wuhan University of Science and TechnologyWuhanChina Department of Hepatology of Integrated Traditional Chinese and Western Medicine The Third People's Hospital of Hubei Province Affiliated to Jianghan UniversityWuhanChina Division of Oncology Liyuan HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Yangchunhu Community Hospital Liyuan HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Cancer Center Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Hubei Key Laboratory of Precision Radiation Oncology WuhanChina Institute of Radiation Oncology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

Background:In vivo experiments were conducted to examine the effects of the targeted drug anlotinib on the stemness of hepatocellular carcinoma(HCC)cells and lenvatinib-resistant liver cancer cells and to explore the underlying molecular ***:A subcutaneous xenograft model of Hep3B-derived HCC was established in nude mice,which were randomly divided into 2 groups(n=5 males per group):(1)intragastric administration of anlotinib(0.4 mg/kg)and(2)intragastric administration of normal *** constructed lenvatinib-resistant cell lines and randomly divided the mice into 3 groups(n=5 males per group):(1)intragastric administration of anlotinib,(2)intragastric administration of lenvatinib,and(3)intragastric administration of normal *** 2 weeks of treatment,tumor tissues were harvested,and mRNA and proteins were isolated from the *** in the expression of cancer stemness markers(epithelial cell adhesion molecule[EpCAM],CD13,CD90,aldehyde dehydrogenase 1[ALDH1],CD44,and CD45),totipotency factors(sex-determining region Y-box 2[Sox2],Nanog,octamer-binding transcription factor 4[Oct4]),and genes related to the Notch signaling pathway were ***:Compared with that in the control group,tumor size and weight were reduced in nude mice treated with *** differences were statistically significant in both the types of nude *** affected stemness markers and totipotency factors by downregulating the expression of CD133,CD90,and G-protein–coupled receptor 5(LGR5)and upregulating the expression of intercellular adhesion molecule 1(ICAM-1)and *** addition,lenvatinib-resistant cell lines increased Notch signaling pathway,whereas anlotinib inhibited Notch signaling ***:The antitumor effect of anlotinib on HCC and lenvatinib-resistant HCC cellsmay occur through inhibition of the Notch signaling *** may be the drug of choice for sequential therapy in lenvatinib-resistant liver cancer.

关键词： Anlotinib HCC Lenvatinib-resistant Notch signaling pathway

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Integrated gut microbiota,plasma metabolomics and network pharmacology to reveal the anti-ischemic stroke effect of cooked rhubarb

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Traditional Medicine Research 2024年第9期9卷 1-13页

作者： Ting Li Lan-Fang Tan Lin Shen Jie-Hui Kuang Si-Kai zhan.Bang Liu Jia-Le Cai Sheng-Wang Liang Ming-Hua Xian shu-Mei Wang School of Chinese Materia Medica Guangdong Pharmaceutical UniversityGuangzhou 510006China Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM School of Chinese Materia MedicaGuangdong Pharmaceutical UniversityGuangzhou 510006China Engineering&Technology Research Center for Chinese Materia Medica Quality of the Universities of Guangdong Province School of Chinese Materia MedicaGuangdong Pharmaceutical UniversityGuangzhou 510006China Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization Guangxi Institute of BotanyChinese Academy of SciencesGuilin 541006China Traditional Chinese Medicine Resource Germplasm Bank Management Center Yunfu 527300China

Background:Cooked rhubarb(CR)is obtained by steaming raw rhubarb(Rheum palmatum L.,Rheum officinale Baill.,or Rheum tanguticum *** Balf.)with millet *** is used as a traditional Chinese medicine for treating cerebral stroke,where patients often face severe *** study explored the pharmacological effects and mechanisms of CR against ischemic stroke(IS)in *** used integrated analysis of gut microbiota,metabolomics,and network ***:The compounds in CR were identified using LC-MS/*** impact of CR on rat middle cerebral artery occlusion/reperfusion(MCAO/R)-induced cerebral infarct size and brain tissue pathology was assessed through 2,3,5-triphenyl tetrazolium chloride and HE *** in hemorheology were measured by evaluating blood viscosity,and serum levels of pro-inflammatory cytokine were also *** microbiota composition was analyzed through 16S rRNA gene *** metabolites were examined using untargeted metabolomics and Spearman correlation *** pseudo-germ-free test was used to determine whether tumour necrosis factor-α(TNF-α)and interleukin-1β(IL-1β)improvement in IS are dependent on gut ***:In vivo studies showed CR enhances neurobehavioral function in MCAO/R rats and reduces cerebral infarction *** also ameliorates brain and intestinal barrier damage caused by *** also decreased inflammation and oxidative stress in IS ***,CR promotes the growth of Akkermansia and Verrucomicrobia,aiding in intestinal barrier ***,CR primarily influences the primary bile acid biosynthesis *** pseudo-germ-free experiment and network pharmacology confirmed TNF-αand IL-1βas potential *** relies on gut microbiota for its anti-inflammatory effects to improve ***:Cooked rhubarb offers neuroprotective benefits by enhancing beneficial bacteria abundance and regulating bile acid *** emerges as a potential therapeutic agent for

关键词： cooked rhubarb ischemic stroke gut microbiota metabolomics