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A Comparative Study on the Post-Buckling Behavior of Reinforced Thermoplastic Pipes(RTPs)Under External Pressure Considering Progressive Failure

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China Ocean Engineering 2024年第2期38卷 233-246页

作者： DING Xin-dong WANG shu-qing liu Wen-cheng YE Xiao-han College of Engineering Ocean University of ChinaQingdao 266100China Shandong Provincial Key Laboratory of Ocean Engineering Ocean University of ChinaQingdao 266100China Department of Marine Technology Norwegian University of Science and Technology(NTNU)Trondheim NO-7491Norway

The collapse pressure is a key parameter when RTPs are applied in harsh deep-water *** investigate the collapse of RTPs,numerical simulations and hydrostatic pressure tests are *** the numerical simulations,the eigenvalue analysis and Riks analysis are combined,in which the Hashin failure criterion and fracture energy stiffness degradation model are used to simulate the progressive failure of composites,and the“infinite”boundary conditions are applied to eliminate the boundary *** for the hydrostatic pressure tests,RTP specimens were placed in a hydrostatic chamber after filled with *** has been observed that the cross-section of the middle part collapses when it reaches the maximum *** collapse pressure obtained from the numerical simulations agrees well with that in the ***,the applicability of NASA SP-8007 formula on the collapse pressure prediction was also *** has a relatively greater difference because of the ignorance of the progressive failure of *** the parametric study,it is found that RTPs have much higher first-ply-failure pressure when the winding angles are between 50°and 70°.Besides,the effect of debonding and initial ovality,and the contribution of the liner and coating are also discussed.

关键词： reinforced thermoplastic pipes post-buckling behavior progressive failure of composites debonding initial ovality

Spatial heterogeneity and compositional profiles of dissolved organic matter in farmland soils across China' Mainland

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Journal of Environmental Sciences 2024年第3期137卷 593-603页

作者： Bingjun Han Liyuan Chen Kang Xiao Yang liu dong Cao Lu Yu Yujun Li shu Tao Wenxin liu Key Laboratory for Earth Surface Processes College of Urban and Environmental SciencesPeking UniversityBeijing 100871China Beijing Yanshan Earth Critical Zone National Research Station College of Resources and EnvironmentUniversity of Chinese Academy of SciencesBeijing 101408China Center for Water and Ecology State Key Joint Laboratory of Environment Simulation and Pollution ControlSchool of EnvironmentTsinghua UniversityBeijing 100084China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental ScienceChinese Academy of SciencesBeijing 100085China

Dissolved organic matter(DOM) plays an essential role in many geochemical processes,however its complexity, chemical diversity, and molecular composition are poorly understood. Soil samples were collected from 500 vegetable fields in administrative regions of China' Mainland, of which 122 were selected for further investigation. DOM properties were characterized by three-dimensional excitation-emission matrix(3D-EEM) fuorescence spectroscopy and Fourier transform ion cyclotron resonance mass spectrometry(FTICRMS)(field intensity is 15 Tesla). Our results indicated that the main constituents were UVA humic-like substances, humic-like substances, fulvic acid-like substances, and tyrosine-like substances. A total of 10,989 molecular formulae with a mass range of 100.04 to 799.59 Da were detected, covering the mass spectrometric information of the soil samples from 27 different regions. CHO and CHON molecules were dominant in DOM, whereas lignin, tannins,and aromatic substances served as the main components. The results of cluster analysis revealed that the soil properties in Jiangxi Province were considerably different from those in other regions. The key backgrounds of the DOM molecular characteristics in the vegetablefield soil samples across China' Mainland were provided at the molecular level, with large abundance and great variability.

关键词： Dissolved organic matter(DOM) Fourier transform ion cyclotron resonance mass(FTICR-MS) Excitation-emission matrix(EEM) Vegetable-field soils China' Mainland

Coupled interactive effects of ammonia and hydrogen additions on ethylene diffusion flames: A detailed kinetic study

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Science China(Technological Sciences) 2024年第3期67卷 930-948页

作者： XIAO JiaYi XU TingTing shu ZhiMei DENG QiGe ZHAO Xuan YING YaoYao LI TianJiao liu dong MIIT Key Laboratory of Thermal Control of Electronic Equipment School of Energy and Power EngineeringNanjing University of Science and TechnologyNanjing 210094China Advanced Combustion Laboratory School of Energy and Power EngineeringNanjing University of Science and TechnologyNanjing210094China

In order to create effective combustion technologies and fuels with low or no carbon emissions,the research was conducted to assess the coupled interactive effects of NH_(3) and H_(2) additions on ethylene counterflow diffusion flames from a kinetic *** effects of the NH_(3)/H_(2) combination on flame temperatures,major species,key radicals,important intermediate species,representative oxygenated species and NO_xwere *** results of the study utilizing fictitious inert NH_(3) and/or H_(2) revealed the chemical effects of the two *** was found that the NH_(3)/H_(2) coupled effects had a more effective inhibitory effect on soot precursors than the effects of corresponding sum of single NH_(3) or H_(2) *** production of soot precursors was promoted by the coupled chemical effects of NH_(3) and H_(2),but the coupled dilution and thermal effects were observed to have a greater impact,resulting in a decrease of the mole fractions of soot *** for the interaction of NH_(3) and H_(2) effects,the presence of H_(2) decreased the chemical effects of NH_(3) on the augmentation of C_(2)H_(2),A1,A2,and CH_(3)CHO mole *** NH_(3) addition alleviated the H_(2) chemical effects on increasing C_(2)H_(2),C_(3)H_(3),A1 and A2 ***,the NH_(3)chemical effects on C_(3)H_(3),OH and CH_(3)CHO were enhanced when H_(2) was *** presence of NH_(3) augmented the chemical effects of H_(2) on the growth of OH mole ***,the H_(2) chemical effects hindered the production of NO and NO_(2) in the presence of NH_(3).

关键词： NH_(3)/H_(2)addition kinetic analysis coupled interactive effects chemical effects

Modeling urban scale human mobility through big data analysis and machinelearning

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Building Simulation 2024年第1期17卷 3-21页

作者： Yapan liu Bing dong Department of Mechanical&Aerospace Engineering Syracuse University263 Link HallSyracuseNY 13244USA

In the United States,the buildings sector consumes about 76%of electricity use and 40% of all primary energy use and associated greenhouse gas *** behavior has drawn increasing research interests due to its impacts on the building energy ***,occupant behavior study at urban scale remains a challenge,and very limited studies have been *** an effort to couple big data analysis with human mobility modeling,this study has explored urban scale human mobility utilizing three months Global Positioning System(GPS)data of 93,o00 users at Phoenix Metropolitan *** research extracted stay points from raw data,and identified users'home,work,and other locations by Density-Based Spatial Clustering ***,daily mobility patterns were constructed using different types of *** propose a novel approach to predict urban scale daily human mobility patterns with 12-hour prediction horizon,using Long Short-Term Memory(LSTM)neural network *** shows the developed models achieved around 85%average accuracy and about 86%mean *** developed models can be further applied to analyze urban scale occupant behavior,building energy demand and flexibility,and contributed to urban planning.

关键词： urban human mobility big data analysis urban scale occupant behavior recurrent neural networks

Comprehensive kinetic study on ammonia/ethylene counter-flow diffusion flames:influences of diluents

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International Journal of Coal Science & Technology 2024年第1期11卷 232-249页

作者： Zhimei shu Tingting Xu Jiayi Xiao Qige Deng Xuan Zhao Tianjiao Li Yaoyao Ying dong liu MIIT Key Laboratory of Thermal Control of Electronic Equipment School of Energy and Power EngineeringNanjing University of Science and TechnologyNanjing210094China Advanced Combustion Laboratory School of Energy and Power EngineeringNanjing University of Science and TechnologyNanjing210094China

This study aimed to investigate the effects of ammonia addition on ethylene counter-flow diffusion flames with different diluents on the fuel or oxidizer side,using kinetic analyses.A special emphasis was put on assessing the coupled chemical effects of NH_(3) and CO_(2) on C2H4 combustion *** chemical effects could be evaluated by comparing fictitious inert NH_(3) or CO_(2) with normal active NH_(3) or CO_(2).The results revealed that the addition of NH_(3) decreased the mole fractions and production rates of key soot precursors,such as acetylene,propynyl,and *** CO_(2) was used as the dilution gas,the coupled chemical effects of NH_(3) and CO_(2) were affected by the chemical effects of CO_(2) to varying *** the oxidizer-side CO_(2) addition,the coupled chemical effects of NH_(3) and CO_(2) reduced the mole fractions of H,O,OH radicals,acetylene,propynyl,and benzene,while the effects differed from the fuel-side CO_(2) *** coupled chemical effects of NH_(3) and CO_(2) also promoted the formation of aldehyde contaminants,such as acetaldehyde,to some extent,particularly with CO_(2) addition on the oxidizer side.

关键词： Ammonia addition Diluents Coupled chemical effects Kinetic analysis

Natural product-induced oxidative stress-synergistic anti-tumor effects of chemotherapeutic agents

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Traditional Medicine Research 2024年第3期9卷 10-23页

作者： shu-Fan Wang Shi-Qi dong Quan dong Wen-Xin Lin Mei dong Duo liu Department of Pharmacy Harbin Medical University Cancer HospitalHarbin 150086China

Reactive oxygen species are closely related to tumor *** recent years,reactive oxygen species has become a hot spot in tumor therapy,and many natural substances in nature contain compound components with anti-tumor ***,there is a lack of discussion on the synergistic anti-tumor effects of natural products in combination with chemotherapeutic drugs through reactive oxygen *** terms“natural products”,“reactive oxygen species”,“anti-tumor”,and“chemotherapy”were used to identify the synergistic effects of natural *** conducted a systematic literature search in PubMed and Web of Science databases for relevant research articles and reviews published in recent *** systematically summarized the studies related to anti-tumor active ingredients in natural compounds in the field of reactive oxygen species in recent years.A total of 77 relevant literatures were *** them,45 literatures containing various natural products such as terpenoids,flavonoids,alkaloids,*** anti-tumor effects by regulating reactive oxygen species levels,and 32 literatures regarding adjunctive role of natural products in anti-tumor *** this study,we found that natural products exert anti-tumor effects by elevating reactive oxygen species *** provides strong theoretical support for future clinical studies.

关键词： nature products tumor reactive oxygen species combination chemotherapy oxidative stress

MFG-E8 Alleviates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Phagocytosing Myelin Debris and Promoting Remyelination

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Neuroscience Bulletin 2024年第4期40卷 483-499页

作者： Xiaohong dong Zhi Zhang Xin shu Zi Zhuang Pinyi liu Renyuan liu Shengnan Xia Xinyu Bao Yun Xu Yan Chen Department of Neurology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing210008China Department of Neurology Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjing210008China Department of Neurology Drum Tower Hospital of Nanjing Medical UniversityNanjing210008China Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjing210008China Jiangsu Provincial Key Discipline of Neurology Nanjing210008China

Chronic cerebral hypoperfusion is one of the pathophysiological mechanisms contributing to cognitive decline by causing white matter *** phagocytosing myelin debris in a timely manner can promote remyelination and contribute to the repair of white ***,milk fat globule-epidermal growth factor-factor 8(MFG-E8),a microglial phagocytosis-related protein,has not been well studied in hypoperfusion-related cognitive *** found that the expression of MFG-E8 was significantly decreased in the brain of mice after bilateral carotid artery stenosis(BCAS).MFG-E8 knockout mice demonstrated more severe BCAS-induced cognitive impairments in the behavioral *** addition,we discovered that the deletion of MFG-E8 aggravated white matter damage and the destruction of myelin microstructure through fluorescent staining and electron ***,MFG-E8 overexpression by AAV improved white matter injury and increased the number of mature oligodendrocytes after ***,in vitro and in vivo experiments showed that MFG-E8 could enhance the phagocytic function of microglia via theαVβ3/αVβ5/Rac1 pathway and IGF-1 production to promote the differentiation of oligodendrocyte progenitor cells into mature ***,we found that MFG-E8 was mainly derived from astrocytes,not *** findings suggest that MFG-E8 is a potential therapeutic target for cognitive impairments following cerebral hypoperfusion.

关键词： White matter injury Cognitive dysfunction MFG-E8 Remyelination Microglial phagocytosis

Dexamethasone implant for refractory macular edema secondary to diabetic retinopathy and retinal vein occlusion

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1837-1842页

作者： Yuan-Yuan Zhong Chong Tang Lan-Yue Zhang Xue-dong Zhang shu-Lin liu The First Affiliated Hospital of Chongqing Medical University Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye DiseasesChongqing 400016China

AIM:To evaluate the efficacy,timing of retreatment and safety of dexamethasone(DEX)implant on macular edema(ME)secondary to diabetic retinopathy(DME)and retinal vein occlusion(RVO-ME)patients who were refractory to anti-vascular endothelial growth factor(VEGF)***:This retrospective study included 37 eyes received at least one DEX implant treatment for DME or RVO-ME between January 1,2019,and January 1,*** refractory DME and RVO-ME cases received at least 5 anti-VEGF injections and failure to gain more than 5 letters or a significant reduction in central retinal thickness(CRT).The best corrected visual acuity(BCVA)and CRT were measured at baseline,and at 1,3,4 and 6mo post-DEX implant *** events such as elevated intraocular pressure(IOP)and cataract were ***:For RVO cases(n=22),there was a significant increase in BCVA from 0.27±0.19 to 0.35±0.20 at 6mo post-DEX injection(P<0.05)and CRT decreased from 472.1±90.6 to 240.5±39.0μm at 6mo(P<0.0001).DME cases(n=15)experienced an improvement in BCVA from 0.26±0.15 to 0.43±0.20 at 6mo post-DEX implant injection(P=0.0098),with CRT reducing from 445.7±55.7 to 271.7±34.1μm at 6mo(P<0.0001).Elevated IOP occurred in 45.9%of patients but was well-controlled with topical *** cases of cataract or other adverse events were ***:DEX implants effectively improve BCVA and reduce CRT in refractory DME and *** research with larger cohorts and longer follow-up periods is needed to confirm these findings and assess long-term outcomes.

关键词： macular edema dexamethasone implant anti-vascular endothelial growth factor retinal vein occlusion diabetic retinopathy

Combustion characteristics of millimeter-sized aluminum particles in fluidized bed under various O_(2)/CO_(2)/H_(2)O atmospheres Author links open overlay panel

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Particuology 2024年第8期91卷 315-322页

作者： Jialing Zhou Rui Zhang dong liu Key Laboratory of Thermal Control of Electronic Equipment Ministry of Industry and Information TechnologyNanjing210094China Advanced Combustion Laboratory School of Energy and Power EngineeringNanjing University of Science and TechnologyNanjing210094China

Aluminum is an attractive alternative fuel,but it burns very inefficiently due to the formation of a dense Al_(2)O_(3)layer which prevents O_(2)from diffusion to the surface of Al *** previous experiments,the combustion of millimeter-sized Al(mAl)particles in the fluidized bed has achieved a substantial increase in the combustion efficiency,but further improvements are still *** this study,the effects of reaction atmosphere on the fluidized combustion of mAl particles were *** experiments with different O_(2)/H_(2)O/CO_(2)concentrations were *** experimental results indicate that the combustion efficiency of mAl particles in fluidized bed increases as the mole fraction of O_(2),H_(2)O or CO_(2)increases,and the highest combustion efficiency can reach 38.7%.After the analysis of the oxide film on the surface of aluminum particles,it was found that it is easier to generate the unstableθ-Al_(2)O_(3)under CO_(2)atmosphere,and it is easier to generate the unstableγ-Al_(2)O_(3)andθ-Al_(2)O_(3)under H_(2)O *** unstable Al_(2)O_(3)film is more likely to be abraded in the fluidized bed,which leads to the effective improvement of the combustion efficiency.

关键词： Al combustion Fluidized bed Atmosphere Combustion efficiency