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Burden of atrial fibrillation in patients with rheumatic diseases

World Journal of Clinical Cases 2021年第14期9卷 3252-3264页

作者： Muhammad Zubair Khan Kirtenkumar Patel Krunalkumar A Patel Rajkumar Doshi Vraj Shah Devina Adalja Zainulabedin Waqar Sona Franklin Neelesh Gupta Muhammad Hamdan Gul shruti jesani Steven Kutalek Vincent Figueredo Department of Internal Medicine St.Mary Medical CenterLanghornePA 19047United States Division of Cardiology North Shore University HospitalManhassetNY 11030United States Department of Internal Medicine University of Nevada Reno School of MedicineRenoNV 89502United States Division of Cardiology Medical College of BarodaBaroda 390001India Department of Internal Medicine GMERS Gotri Medical CollegeVadodara 390021India Department of Internal Medicine Mercy St.Vincent Medical CenterToledoOH 43608United States Department of Internal Medicine Nazareth HospitalPhiladelphiaPA 19115United States Department of Internal Medicine Saint Joseph HospitalChicagoIL 60657United States Department of Internal Medicine Trinitas Regional Medical CenterElizabethNJ 07202United States Department of Cardiology St.Mary Medical CenterLanghornePA 19047United States

BACKGROUND Studies have suggested that atrial fibrillation(AF)in patients with rheumatic diseases(RD)may be due to *** morbidity and mortality associated with AF in hospitalized patients with *** The National inpatient sample database from October 2015 to December 2017 was analyzed to identify hospitalized patients with RD with and without AF.A subgroup analysis was performed comparing outcomes of AF among different *** The prevalence of AF was 23.9%among all patients with RD(n=3949203).Among the RD subgroup,the prevalence of AF was highest in polymyalgia rheumatica(33.2%),gout(30.2%),and pseudogout(27.1%).After adjusting for comorbidities,the odds of having AF were increased with gout(1.25),vasculitis(1.19),polymyalgia rheumatica(1.15),dermatopolymyositis(1.14),psoriatic arthropathy(1.12),lupus(1.09),rheumatoid arthritis(1.05)and pseudogout(1.04).In contrast,enteropathic arthropathy(0.44),scleroderma(0.96),ankylosing spondylitis(0.96),and Sjorgen’s syndrome(0.94)had a decreased association of *** mortality,length of stay,and hospitalization costs were higher in patients with RD having AF vs without *** the RD subgroup,the highest mortality was found with scleroderma(4.8%),followed by vasculitis(4%)and dermatopolymyositis(3.5%).CONCLUSION A highest association of AF was found with gout followed by vasculitis,and polymyalgia rheumatica when compared to other *** was two-fold higher in patients with RD with AF.

关键词： Atrial fibrillation Rheumatic diseases Lupus Gout Scleroderma Vasculitis

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