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Finite Groups Whose Nontrivial Normal Subgroups Have Order Two

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Journal of Mathematical Research and Exposition 2011年第4期31卷 675-680页

作者： shou hong qiao Da Chang GUO School of Applied Mathematics Guangdong University of Technology Guangdong 510006 P. R. China

In this paper, we investigate the structure of the groups whose nontrivial normal subgroups have order two. Some properties of this kind of groups are obtained.

关键词： finite groups normal subgroups soluble groups insoluble groups simple groups

Tetrahedron constellation of gravitational wave observatory

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Science China(Physics,Mechanics & Astronomy) 2025年第2期68卷 86-93页

作者： hong-Bo Jin Cong-Feng qiao National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China International Centre for Theoretical Physics Asia-Pacific University of Chinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China

For the first time,we have introduced the tetrahedron constellation of gravitational wave observatory(TEGO)composed of four identical spacecrafts(S/Cs).The laser telescopes and their pointing structures are mounted on the S/C platform and are evenly distributed at three locations 120 degrees *** structures form automatically a stable mass center for the *** time delay interferometry(TDI)is used to suppress the frequency noise of gravitational wave(GW)*** unequal-arm Michelson TDI configuration and the Sagnac TDI configuration are equally effective at eliminating the laser frequency noise based on the TEGO ***,compared with the configurations of LISA,Taiji,and Tian Qin,the TEGO has more combinations of optical paths in its TDI system sensitive to GW *** six arms of TEGO are simultaneously sensitive to the six polarization modes of *** sensitivity implies that GW modes beyond the predictions of general relativity(GR)can be detected *** instance,a scalar longitudinal mode of GWs,which is not predicted by GR,has been identified as a dominant polarization *** mode is found to be evident in the response amplitudes of the TEGO arms,such as between S/C1 and S/C4,and S/C3 and S/C4,at certain orbital positions.

关键词： gravitational wave detectors and experiments gravitational waves experimental tests of gravitational theories experimental studies of gravity

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Sky location of massive black hole binaries in the foreground of Galactic white dwarf binaries

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Science China(Physics,Mechanics & Astronomy) 2025年第1期68卷 93-104页

作者： Pan Guo hong-Bo Jin Cong-Feng qiao Yue-Liang Wu The International Centre for Theoretical Physics Asia-Pacific University of Chinese Academy of SciencesBeijing 100190China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China The School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China

For space-based gravitational wave(GW)detection,the main noise source for massive black hole binaries(MBHBs)is attributed to approximately 107 double white dwarf binaries in the *** a GW source,the amplitude of the detector response,recorded by a space-based gravitational wave detector,exhibits a modulation effect with a year period when observing the source from various orbital *** the adverse conditions mentioned above,where there is a strong foreground noise and annual modulation in the signals,we employed the wavelet transform and the strong-amplitude relevant orbital position search methods,which allows the weak MBHB sources to achieve higher locating *** detail,for two MBHB sources of lower intensity,the precision of luminosity distance,represented by the ratioΔD_(L)/D_(L) at the 95%confidence level,is enhanced by factors of∼*** angular resolutions,denoted byΔΩs,are enhanced by a factor of∼*** improvements increase the number of detectable GW sources,facilitate multi-messenger follow-up observations and provide constraints on the cosmological constant.

关键词： space-based gravitational wave detection gravitational waves massive black hole binaries

The cGAS-STING-interferon regulatory factor 7 pathway regulates neuroinflammation in Parkinson's disease

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Neural Regeneration Research 2025年第8期20卷 2361-2372页

作者： Shengyang Zhou Ting Li Wei Zhang Jian Wu Hui hong Wei Quan Xinyu qiao Chun Cui Chenmeng qiao Weijiang Zhao Yanqin Shen Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi Medicine SchoolJiangnan UniversityWuxiJiangsu ProvinceChina

Interferon regulatory factor 7 plays a crucial role in the innate immune ***,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains *** we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial *** the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 *** addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and *** together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.

关键词： cyclic guanosine monophosphate adenosine monophosphate synthase H151 interferon regulatory factor 7 M1 phenotype neurodegenerative disease neuroinflammation Parkinson’s disease RU521 STING type I interferon

Stable copper boron–imidazolate cage as Cu-riched enzyme for highly efficient electrocatalytic CO2 reduction to ethylene

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Science China Chemistry 2025年第03期 943-950页

作者： Jun-Qiang Chen qiao-hong Li Qin-Long hong Ping Shao Hai-Xia Zhang Jian Zhang State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of Sciences

Single-atom catalyst has garnered widespread attention to mimic mature enzymes due to its well-defined atomic structure and coordination ***,since the carbon–carbon（C–C） coupling reactions require synergistic catalysis of multiple sites,single-atom catalysts suffer from insufficient active sites and unclear reaction *** the reaction intermediates in a precisely targeted pocket through careful metal–organic cage design is therefore ***,we prepare a tetrahedral [Cu6L4]-type boron–imidazolate cage integrating highly active Cu sites and optimized cavity,which exhibits enzyme like specific catalytic performance in electrochemical CO2reduction reaction（CO2RR） to enhance the selectivity of *** analyses and computational calculations suggest that the single Cu site together with neighboring boron–imidazolate ligands provides suitably synergistic effects that enable the energetically favorable formation of an*COCHO intermediate,a key step determining *** a result,the [Cu6L4]-type cage of BIC-145 achieves a Faradaic efficiency of 28% for C2H4maintaining an average current density of -3.54 m A cm-2over a 5-hour electrolysis *** work represents the first example for studying single-metal site catalysts with ultra-low coordination numbers through the rational design of metal–organic cages.

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IL-17A mediates inflammation-related retinal pigment epithelial cells injury via ERK signaling pathway

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International Journal of Ophthalmology(English edition) 2025年第1期18卷 15-27页

作者： Hui-Min Zhong Bing-qiao Shen Yu-hong Chen Xiao-Huan Zhao Xiao-Xu Huang Min-Wen Zhou Xiao-Dong Sun Department of Ophthalmology Shanghai General Hospital(Shanghai First People’s Hospital)Shanghai Jiao Tong UniversitySchool of MedicineShanghai 200080China National Clinical Research Center for Ophthalmic Diseases Shanghai 200080China National Clinical Research Center for Eye Diseases Shanghai 200080China Shanghai Key Laboratory of Fundus Diseases Shanghai 200080China Shanghai Engineering Center for Visual Science and Photomedicine Shanghai 200080China

AIM:To investigate whether interleukin-17A(IL-17A)gets involved in the mechanisms of inflammation-related retinal pigment epithelium(RPE)cells injury and its significance in age-related macular degeneration(AMD).MRTHODS:A sodium iodate(NaIO3)mouse model as well as IL-17A-/-mice were *** effects of inflammatory cytokines in RPE cells and retinal microglia before and after NaIO3 modeling in vivo and in vitro,were investigated using immunofluorescence,immunoprotein blotting,and quantitative real-time fluorescence polymerase chain reaction(qRT-PCR),*** using recombinant IL-17A protein(rIL-17A)or IL-17A neutralizing antibody(IL-17A NAb)were used to observe the subsequent differences in fundus,fundus photography and optical coherence tomography(OCT),cell viability,and expression of oxidative stress-related markers before and after modeling,and to screen for key signaling ***:In the scenario of NaIO3 stimulation,RPE cells obviously tended to *** proliferation and activation of retinal microglia was confirmed in NaIO3-stimulated mice,whereas such effects induced by NaIO3 were significantly ameliorated with IL-17A NAb intervention or in IL-17A-/-*** addition,IL-17A promoted the proliferation and activation of microglia as well as oxidative damage and the secretion of inflammatory cytokines alongside NaIO3-induced damage in RPE cells in vivo and ex ***,the extracellular signalregulated kinase(ERK)signaling pathway was shown to be participated in the regulation of NaIO3-induced RPE cells injury mediated by IL-17A in vivo and ex vivo,as IL-17A induced inflammatory cytokines release in the NaIO3 model was alleviated after blocking the ERK ***:IL-17A probably promotes the NaIO3-induced RPE cells injury through exacerbating inflammation in terms of retinal microglia activation and inflammatory cytokines release via ERK signaling *** of IL-17A may be a new potential ta

关键词： age-related macular degeneration retinal pigment epithelium NaIO3 microglia IL-17A

Hydrogen-enhanced light-induced thermoelastic spectroscopy sensing

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Photonics Research 2025年第01期13卷 194-200页

作者： YING HE YUANZHI WANG SHUNDA qiao XIAOMING DUAN hong QI YUFEI MA National Key Laboratory of Laser Spatial Information Harbin Institute of Technology School of Energy Science and Engineering Harbin Institute of Technology

A hydrogen（）-enhanced light-induced thermoelastic spectroscopy（LITES） sensor is proposed for the first time, to our knowledge, in this paper. The enhancement with H2significantly reduces the resonance damping of a quartz tuning fork（QTF）, leading to a 2.5-fold improvement in the quality factor（Q-factor） to 30,000 without introducing additional noise into the LITES sensor system. Based on the H2-enhancement effect, a self-designed round-head QTF with a low resonance frequency（f0） of 9527 Hz and a fiber coupled multipass cell（MPC）with an optical length of 40 m were utilized to increase the energy accumulation time of QTF and the optical absorption of the target gas, respectively, to demonstrate an ultra-highly sensitive C2H2-LITES sensor. The longterm stability of the H2-enhanced C2H2-LITES sensor was investigated based on Allan deviation analysis. With an optimal integration time of 140 s, the minimum detection limit（MDL） was improved to 290 parts per trillion（ppt）. Compared to other reported state-of-the-art C2H2-LITES techniques with similar parameters, this sensor shows a 241-fold improvement in the MDL. This H2-enhancement technique proves to be a highly effective method for achieving a high Q-factor QTF, characterized by its simplicity and efficiency. It offers substantial potential for applications in QTF-based gas sensing.

关键词： High power lasers Hydrogen Optical absorption Photoacoustic effect Photoacoustic spectroscopy Sensor performance

GPS: graph contrastive learning via multi-scale augmented views from adversarial pooling

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Science China(Information Sciences) 2025年第1期68卷 145-158页

作者： Wei JU Yiyang GU Zhengyang MAO Ziyue qiao Yifang QIN Xiao LUO Hui XIONG Ming ZHANG School of Computer Science National Key Laboratory for Multimedia Information ProcessingPeking University Artificial Intelligence Thrust The Hong Kong University of Science and Technology Department of Computer Science University of California

Self-supervised graph representation learning has recently shown considerable promise in a range of fields, including bioinformatics and social networks. A large number of graph contrastive learning approaches have shown promising performance for representation learning on graphs, which train models by maximizing agreement between original graphs and their augmented views(i.e., positive views). Unfortunately, these methods usually involve pre-defined augmentation strategies based on the knowledge of human experts. Moreover, these strategies may fail to generate challenging positive views to provide sufficient supervision signals. In this paper, we present a novel approach named graph pooling contrast(GPS) to address these *** by the fact that graph pooling can adaptively coarsen the graph with the removal of redundancy, we rethink graph pooling and leverage it to automatically generate multi-scale positive views with varying emphasis on providing challenging positives and preserving semantics, i.e., strongly-augmented view and weakly-augmented view. Then, we incorporate both views into a joint contrastive learning framework with similarity learning and consistency learning, where our pooling module is adversarially trained with respect to the encoder for adversarial robustness. Experiments on twelve datasets on both graph classification and transfer learning tasks verify the superiority of the proposed method over its counterparts.

关键词： graph representation learning graph neural networks graph contrastive learning graph augmentations graph pooling

Efficacy of ultrasound cyclo-plasty in patients with refractory glaucoma

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International Journal of Ophthalmology(English edition) 2025年第3期18卷 420-423页

作者： Hui-Min Zhong Xiao-hong Liu shou-Yue Huang Hui-Ping Yao Yi-Sheng Zhong Jing Wang Department of Ophthalmology Ruijin Hospital Affiliated Medical SchoolShanghai Jiao Tong UniversityShanghai 200025China Department of Ophthalmology Shanghai General Hospital(Shanghai First People’s Hospital)Shanghai Jiao Tong UniversityShanghai 200080China

AIM:To assess the efficacy and safety of ultrasound cycloplasty(UCP)in lowering intraocular pressure(IOP)among Chinese patients suffering from refractory ***:In this 12-month retrospective study,28 patients with refractory glaucoma(IOP≥25 mm Hg)were treated with 8-second UCP using either 8 or 10 probe *** principal measure of efficacy was the decrease in IOP at the following intervals after UCP:1d,1,3,6,and 12mo,with each measurement compared to ***:Mean IOP(in mm Hg)was reduced from 46.8±8.9 to 24.5±3.2,27.0±4.8,29.1±4.6,26.1±4.5,and 28.3±4.8 at 1d,1,3,6,and 12mo postoperatively,*** to baseline,IOP reductions at these time points were 45.0%,39.9%,35.3%,41.4%,and 36.7%,*** patients experienced relief from ocular pain after *** cases of choroidal detachment or hypotony was ***:UCP is effective in reducing IOP among Chinese patients with refractory glaucoma and shows a favorable safety profile.

关键词： ultrasound cyclo-plasty refractory glaucoma intraocular pressure