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3 T T2FLAIR在检测急性视神经炎视神经乳头水肿诊断的高准确性

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国际医学放射学杂志 2024年第3期 372-372页

作者： N.shor C.Lamirel S.Rebbah C.vignal v.vasseur J.Savatovsky 孔令红

摘要目的三分之一的视神经炎（ON）病人眼底镜可检测到视神经乳头水肿（ONHE）。虽然ONHE是一个重要的症状学特征，但ONHE与视神经乳头MRI异常（ONHMA）（有

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支配润滑油减摩添加剂选择的一些关系

固体润滑 1990年第3期10卷 236-238页

作者： v.L.Lashkhi G.I.shor I.A.Buyanovskii L.v.Borenko S.D.Likhterov 周春红

改善润滑油的减摩性既可以降低摩擦,又是各种摩擦副中最有效的节能措施之一。尤其在边界润滑条件下,使用高温下仍可保持效能的减摩剂就能达到这种目的。为了便于在应用中寻找有效的材料,就必须对这类添加剂进行机理方面的研究。这种研... 详细信息

改善润滑油的减摩性既可以降低摩擦,又是各种摩擦副中最有效的节能措施之一。尤其在边界润滑条件下,使用高温下仍可保持效能的减摩剂就能达到这种目的。为了便于在应用中寻找有效的材料,就必须对这类添加剂进行机理方面的研究。这种研究是提供构思客观的减摩剂作用机理模型的基础,并能提出摩擦学参数与添加剂分子结构及活性之间的定量关系。

关键词：润滑油减摩添加剂

A Possibility of Application of Wave Flow Method for visualization of shor States

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International Journal of Communications, Network and System Sciences 2013年第12期6卷 485-488页

作者： v. K. voronov Irkutsk State Technical University Irkutsk Russia

The present work provides a brief analysis of experimental investigations related to quantum computer creation. The first step to the real quantum creation could be visualization of shor states. Such visualization is based on the use of the phenomenon of the secondary wave generated by incident electromagnetic irradiation on the object which undergoes screening. This electromagnetic irradiation under certain conditions can be transformed into waves of other type, for example, surface plazmons. The massif from n quantum objects generating secondary irradiation, in principle, can be considered as a route to materialization on shor cells. In such a way, a system of q-bites of quantum computer can be realized.

关键词： Quantum Computer shor States NMR

子宫内膜异位症患者局部与全身辅助性T细胞因子与淋巴细胞活性改变

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世界核心医学期刊文摘（妇产科学分册） 2006年第5期2卷 27-27页

作者： Antsiferova Y.S Sotnikova N.Yu Posiseeva L.v shor A.L. 李跃萍 Myakisheva St. 5- 24 153009 Ivanovo Russian Federation

To estimate regulatory cytokine synthesis and lymphocyte activation in the peripheral blood and endometrial tissue of patients with endometriosis. Design: Controlled clinical study. Setting: Medical center. Patient(s): Fifteen women with laparoscopically diagnosed endometriosis; 20 gynecologically healthy women with previously documented fertility (control group). Intervention(s): Peripheral venous blood sampling; laparoscopic collection of ectopic and matched eutopic endometrium. Main Outcome Measure(s): Messenger RNA (mRNA) for interleukin (IL)- 2, IL- 4, and IL- 10 expression in peripheral and endometrium lymphocyteMs was assessed by real-time reverse transcriptase polymerase chain reaction; intracellular synthesis of these cytokines and lymphocyte phenotype profile were established by flow cytometry. Result(s): Both mRNA expression and intracellular synthesis of IL- 4 and IL- 10 were sharply increased in peripheral lymphocytes. The same changes were observed for IL- 4 in ectopic endometrium of women with endometriosis. Simultaneously, elevation of the amount of pan- B cells, CD20+ CD5+ B- 1 cells, and activated HLA- DR+ CD20+ B lymphocytes was observed in endometriosis lesions. Only an enhanced amount of B lymphocytes was seen in eutopic endometrium. Conclusion(s): Endometriosis development is accompanied by the activation of a T- helper type 2 immune response at the systemic and local levels. Our results support the hypothesis regarding the autoimmune nature of endometriosis and can explain the high level of autoantibody production in patients with endometriosis.

关键词：子宫内膜异位症细胞因子静脉取血表型特征腔镜外周淋巴细胞流式细胞仪检测自身免疫反应反转

Human Pro-insulin Transgenic Calf Derived from Somatic Cell Nuclear Transfer

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Zoological Research 2007年第4期28卷 409-416页

作者：杨东山郭旭东海棠杜晨光王建国仓明刘东军李喜和旭日干哺乳动物生殖生物学及生物技术教育部重点实验室 Department of Clinical veterinary Medicine University of Cambridge

The current study was undertaken to evaluate the possibility of producing a human pro-insulin transgenic cow by means of somatic cell nuclear transfer （SCNT）. A double selection system, Neomycin resistance （Neo^r） gene and enhanced green fluorescent protein （EGFP） gene linked through an inner ribosomal entry site （IRES） sequence directed by a Cytomegalovirus （CMv） promoter, was used for enrichment and selection of the transgenic cells and preimplantation embryos. Transgenes were introduced into bovine fetal fibroblast cells （BFF） cultured in vitro through electroporation （900 v/cm, 5 ms）. Transgenic bovine fibroblast cells （TBF） were enriched through addition of G418 in culture medium （800 μg/mL）. Before being used as a nuclear donor, the TBF cells were either cultured in normal conditions （10% FBS） or treated with serum starvation （0.5% FBS for 2-4 days） followed by 10 hours recovery for G1 phase synchronization. Transgenic cloned embryos were produced through GFP-expressing cell selection and SCNT. The results were the percentage of blastocyst development following SCNT was lower using TBF than BFF cells （23.2% vS 35.2%, P 〈 0.05）. No difference in the percentage of cloned blastocysts between the two groups of transgenic nuclear donor of normal and starvation cultures were observed （23.2% vS 18.9%, P 〉 0.05）. Two to four GFP-expressing blastocysts were transferred into the uterus of each synchronised recipient. One pregnancy from of seven recipients （21 embryos） was confirmed by rectum palpation 60 days after embryo transfer and one recipient has given birth to a calf at term. PCR and DNA sequencing analysis confirmed that the calf was produced using human proinsulin transgenic animal.

关键词： Somatic cell nuclear transfer Human pro-insulin EGFP Transgenic calf