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Prosthetic joint infection of the hip and knee due to Mycobacterium species:A systematic review

World Journal of Orthopedics 2022年第5期13卷 503-514页

作者： Asep Santoso Krisna Yuarno Phatama sholahuddin rhatomy Nicolaas Cyrillus Budhiparama Department of Orthopaedic and Traumatology Universitas Sebelas MaretSurakarta and Prof.Dr.R.Soeharso Orthopaedic HospitalSukoharjo 57162Indonesia Department of Orthopaedic and Traumatology Universitas BrawijayaSaiful Anwar General HospitalMalang 65112Indonesia Department of Orthopaedic and Traumatology Universitas Gadjah MadaYogyakarta and Dr.Soeradji Tirtonegoro General HospitalKlaten 57424Indonesia Nicolaas Institute of Constructive Orthopaedic Research and Education Foundation at Medistra Hospital Jakarta 12950Indonesia Faculty of Medicine Universitas AirlanggaJawa Timur 60132Indonesia Department of Orthopaedics Leiden University Medical CenterLeiden 2333Netherlands

BACKGROUND Mycobacterium species(Mycobacterium sp)is an emerging cause of hip and knee prosthetic joint infection(PJI),and different species of this organism may be responsible for the *** To evaluate the profile of hip and knee Mycobacterium PJI cases as published in the past 30 *** A literature search was performed in PubMed using the MeSH terms“Prosthesis joint infection”AND“Mycobacterium”for studies with publication dates from January 1,1990,to May 30,*** avoid missing any study,another search was performed with the terms“Arthroplasty infection”AND“Mycobacterium”in the same period as the previous *** Preferred Reporting Items for Systematic Reviews and Meta-Analyses chart was used to evaluate the included studies for further *** total,51 studies were included for further evaluation of thecases,type of pathogen,and treatment of PJI caused by Mycobacterium *** Seventeen identified Mycobacterium sp were reportedly responsible for hip/knee PJI in 115 hip/knee PJI cases,whereas in two cases there was no mention of any specific Mycobacterium *** tuberculosis(***)was detected in 50/115(43.3%)of the *** mycobacteria(NTM)included ***(26/115,22.6%),***(10/115,8.6%),***(8/115,6.9%),and ***(8/115,6.9%).Majority of the cases(82/114,71.9%)had an onset of infection>3 mo after the index surgery,while in 24.6%(28/114)the disease had an onset in≤3 *** intraoperative PJI diagnosis was made in 4 cases(3.5%).Overall,prosthesis removal was needed in 77.8%(84/108)of the cases to treat the *** infection rate was controlled in 88/102(86.3%)patients with Mycobacterium *** infection occurred in 10/108(9.8%)patients,while 4/108(3.9%)patients died due to the *** At least 17 Mycobacterium sp can be responsible for hip/knee *** *** is the most common causal pathogen,NTM should be considered as an emerging cause of hi

关键词： Mycobacterium species Prosthetic joint infection Hip Knee Systematic review

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