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Evaluation of phytochemical properties and in-vitro antibacterial activity of the aqueous extracts of leaf,seed and root of Abrus precatorius Linn. against Salmonella and Shigella

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Asian Pacific Journal of Tropical Biomedicine 2016年第9期6卷 755-759页

作者： Ojo Joseph Sunday shola kola babatunde Adeyinka Elizabeth Ajiboye Racheal Majekodunmi Adedayo Mufutau Adeyemi Ajao Busayo Isreal Ajuwon Department of Biosciences and Biotechnology Kwara State University

Objective:To investigate the phytochemical components of Abrus precatorius(***) and the in-vitro susceptibility of Salmonella typhi and Shigella dysenteriae to the aqueous extracts of *** leaf,seed and ***:The leaf,seed and root of *** were collected and homogenized separately after drying at 40℃ for seven days in hot-air *** aqueous extracts of each of the parts were prepared and subjected to phytochemical *** of 400,300,200,100 mg/mL,of each of the extracts were used for broth dilution in minimum inhibitory concentration(MIC) determination against clinical isolates of Salmonella typhi and Shigella dysenteriae,while 50,40,30,20,and 10 mg/mL dilutions were used for the agar diffusion test and 100 mg/mL and 10 mg/mL of gentamycin were used as controls for broth dilution in MIC determination and agar diffusion test,***:Qualitative study reveals that tannin,saponins,alkaloids,flavonoids,terpenoids,steroids and phenols were present in all of the plant *** leaf has the highest quantities of tannin and *** root generally showed the lowest quantity of all the *** pathogens were susceptible to aqueous extracts of the leaf,stem and root of *** at 50 mg/*** concentrations of 40,30 and 20 mg/mL,all the aqueous extracts of *** showed variation in MIC,but produced no minimum bactericide effect upon *** were variations in diameter of zone of inhibition against the organisms at lower ***:These findings suggest that *** is a valuable source of phytochemicals with promising antibacterial *** this bioactivity,*** could be probed further for toxicity,and to obtain some novel antibacterial molecules.

关键词： Abrus precatorius Phytochemicals Antibacterial susceptibility Salmonella Shigella

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