检索结果-南通市图书馆

World Journal of Pediatric Surgery 2018年第1期1卷 9-11页

作者： Kengo hattori Shigeru Takamizawa Yuichiro Miyake Tomoko Hatata Katsumi Yoshizawa Tomoko Furukawa Yoshiaki Kondo Department of Surgery Nagano Children's HospitalNaganoJapan Department of Radiology Nagano Children's HospitalNaganoJapan

Preoperativedifferential diagnosis between tracheobronchial remnant(TBR)and other typesof congenital esophageal stenosis(CES)is challenging,even when usingendoscopic ultrasonography(EUS).This report is the first to demonstrate theuse of transabdominal(external)ultrasound during balloon dilatation todiagnose TBR in *** simple technique is a promising diagnostic tool forTBR as an alternative to EUS.

关键词： balloon esophageal congenital

Geographic Flower Trait Variation of Aquilegia buergerianaSieb. et Zucc. var. buergerianaon Mt. Norikura and the Utsukushigahara Highland, Japan

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2014年第18期5卷 2686-2692页

作者： Mitsuru hattori Yusuke Nagano Takao Itino Department of Biology Faculty of Science Shinshu University Matsumoto Japan Institute of Mountain Science Shinshu University Matsumoto Japan

Many studies have argued the importance of the flower-pollinator size matching for flower trait diversification. However, non-pollinator agents may also influence flower traits. In this study, we investigated the altitudinal variation of flower size (spur length, stamen length, petal blade length, corolla diameter, and sepal length) and flower visitors of Aquilegia buergeriana var. buergeriana (long-spurred columbine) in central Japan. Although this species was primarily visited by Bombus consobrinus, which has an unvarying mouthpart length, flower sizes varied greatly among populations with no correlation with altitude. These results suggest that non-pollinator and non-meteorological agents, directly and/or indirectly, impose selection pressure on flower size in A. buergeriana.

关键词： Bumblebee Flower Visitor Composition Plant-Pollinator Interaction Ranunculaceae

Pharmacological Evidence for the Involvement of Calcium Entry through TRPV1 Channels in Nifedipine-Induced [Ca2+]i Elevation in Gingival Fibroblasts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pharmacology & Pharmacy 2012年第4期3卷 427-432页

作者： Toshimi hattori Toshiaki Ara Yoshiaki Fujinami Department of Dental Pharmacology Matsumoto Dental University 1780 Hirooka-Gohbara Shiojiri Japan.

Background: Among anti-hypertension drugs, calcium (Ca2+) antagonists cause gingival overgrowth as a side effect. We previously discovered that this side effect was due to elevation of the calcium concentration in the cytosol ([Ca2+]i). Ca2+ entry through non-selective cation channels (NSCCs) and Ca2+ release from intracellular Ca2+ stores are involved in this [Ca2+]i elevation. Furthermore, we discovered that calcium-sensing receptors (CaSRs) participate in nifedipine-induced [Ca2+]i elevation. Transient receptor potential (TRP) channels have been identified as NSCCs. In the present study, we undertook experiments to determine if TRPV1 channels are present in gingival fibroblasts and to ascertain if nifedipine-activated NSCCs are TRPV1 channels. Methods Normal human gingival fibroblast Gin-1 cells were used. The [Ca2+]i was measured using a video-imaging analysis system with the Ca2+-sensitive fluorescent dye fura-2/AM. Results: The NSCC inhibitor SKF96365 significantly inhibited nifedipine-induced [Ca2+]i elevation. TRPV1 channel agonists such as capsaicin, olvanil and resiniferatoxin concentration-dependently elevated the [Ca2+]i. The TRPV1 channel activator anandamide concentration-dependently increased the [Ca2+]i. The TRPV1 channel antagonists capsazepine, AMG9810, iodoresiniferatoxin, ruthenium red, and SB366791 significantly inhibited nifedipine-induced [Ca2+]i elevation. Conclusion: These results suggest that Ca2+ entry through TRPV1 channels is involved in the nifedipine-induced [Ca2+]i elevation seen in gingival fibroblasts. We describe here a modified version of our ‘calcium trigger theory’.

关键词： Nifedipine Gingival Overgrowth Gingival Fibroblast TRPV1 Channel

Geographic Variation in Flower Size and Flower-Visitor Composition of Two Bumblebee-Pollinated, Spring-Flowering Herbs, Lamium albumL. var. barbatum(Lamiaceae) and Meehania urticifolia(Lamiaceae)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2015年第5期6卷 737-745页

作者： Mitsuru hattori Yusuke Nagano Takao Itino Department of Biology Faculty of Science Shinshu University Matsumoto Japan Institute of Mountain Science Shinshu University Matsumoto Japan

Geographic variation of flower size is potentially affected by various biotic and abiotic factors such as pollinator size, abundance of nectar robbers, and temperature. To elucidate the effect of geographic variation of flower-visitor fauna on flower size, we investigated two spring-flowering, bumblebee-pollinated herbs, Lamium album L. var. barbatum (seven populations) and Meehania urticifolia (five populations), in central Japan. Flower-size variations were not correlated with altitude (an index of abiotic environmental change) in either species, but in both species they were related to the local species composition of flower visitors. In L. album, flowers were bigger in populations visited by long-tongued Bombus consobrinus and B. diversus queens, whereas they were smaller in populations visited by short-tongued bees such as Apis mellifera. Flower size did not vary much among populations of M. urticifolia visited by long-tongued bumblebees, but it was uniquely small in a population whose flowers were predominantly visited by the nectar-robbing bee Megachile japonica. In conclusion, both the size and nectar-robbing behavior of bees affect local flower-size adaptation in these two long-tubed, spring-flowering herbs.

关键词： Bumblebee Floral Character Geographic Trait Variation Nectar Robbing Pollination

Synthesis of dammarane-type triterpene derivatives and their ability to inhibit HIV and HCV proteases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synthesis of dammarane-type triterpene derivatives and their...

Elevational Floral Size Variation in Prunella vulgaris

作者：危英 Masao hattori Institute of Natural Medicine University of Toyama 2630 SugitaniToyama 930-0194Japan Department of Pharmacy Guiyang College of Traditional Chinese Medicine50 Shidong RoadGuiyangGuizhou 550002China

We synthesized dammarane-type triterpene derivatives and evaluated their ability to inhibit HIV-1 and HCV proteases to understand their structure-activity *** of the mono- and disuccinyl derivatives(5a-5f) were powerful inhibitors of HIV-1 protease(IC1000 lM).These findings indicated that the mono-succinyl dammarane type derivatives(5a- 5d) selectively inhibited HIV-1 protease and that the di-succinyl(5e,5f) as well as 2,3-seco-2,3-dioic acid(3b) derivatives preferably inhibited both viral proteases.

关键词： Dammarane Triterpene 2,3-seco-Derivative Succinyl derivative HIV-1 protease HCV protease

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2015年第13期6卷 2085-2091页

作者： Shin Egawa Mitsuru hattori Takao Itino Department of Biology Faculty of Science Shinshu University Nagano Matsumoto Japan Institute of Mountain Science Shinshu University Nagano Matsumoto Japan

Floral size is potentially influenced by local pollinators’ body size. As pollinator fauna and size often change with elevation, correlation between elevational variation of pollinator size and floral size is expected. We investigated the variation of floral size in Prunella vulgaris L. (Laminaceae) and the variation of their pollinator fauna along an elevational gradient. We measured the floral size of four traits: corolla length (CL), corolla tube length (CTL), corolla width (CW), and calyx length (CAL), in 23 populations, and found that CL and CTL were negatively correlated with elevation, and CW and CAL were not. Six bumblebee species visited the flower, and the visiting bee fauna differed among populations;the smallest and the largest bumblebee species visited the high elevational range (above 1800 m a. s. l.) populations, and the largest and the second largest bumblebee species visited the middle elevational range (1400 - 1800 m a. s. l.). Although abiotic factors can potentially affect floral size, the fact that we do not find an elevational decrease in CW and CAL suggests that the elevational change in P. vulgaris’s CL and CTL reflects the local pollinator size.

关键词： Bumblebee Flower Size Geographic Trait Variation Pollinator Fauna

Clear cell adenocarcinoma of the colon:A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第7期14卷 1137-1140页

作者： Koichi Soga Hideyuki Konishi Natsuko Tatsumi Chika Konishi Keimei Nakano Naoki Wakabayashi Shoji Mitsufuji Keisho Kataoka Takeshi Okanoue Ken-Ichi Mukaisho Takanori hattori Molecular Gastroenterology and Hepatology Kyoto Prefectural University of Medicine Graduate School of Medical ScienceKyotoJapan Department of Pathology Shiga University of Medical ScienceShigaJapan

A primary clear cell adenocarcinoma of the colon is a rare oncologic entity. We herein report a case of such a tumor of the sigmoid colon in a 71-year-old woman who was successfully treated by an endoscopic polypectomy in our hospital. We also reviewed the published reports regarding cases of primary clear cell tumors in the colon.

关键词： Adenoma-carcinoma sequence Clear cell carcinoma Colonic adenoma Colon cancer Endoscopic polypectomy

Production of a High-Mach-Number Plasma Flow for an Advanced Plasma Space Thruster

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plasma Science and Technology 2004年第6期6卷 2541-2545页

作者： M.Inutake K.Yoshino S.Fujimura H.Tobari T.Yagai Y.Hosokawa R.Sato K.hattori A.Ando Department of Electrical Engineering Tohoku University Sendai 980-8579 Japan

A higher specific impulse and a larger thrust are required for a mannedinterplanetary space thruster. Prior to a realization of a fusion-plasma thruster, amagneto-plasma-dynamic arcjet (MPDA) powered by a fission reactor is one of the promising candidatesfor a manned Mars space thruster. The MPDA plasma is accelerated axially by a self-induced j x Bforce. Thrust performance of the MPDA is expected to increase by applying a magnetic nozzle insteadof a solid nozzle. In order to get a much higher thruster performance, two methods have beeninvestigated in the HITOP device, Tohoku University. One is to use a magnetic Laval nozzle in thevicinity of the MPDA muzzle for converting the high ion thermal energy to the axial flow energy. Theother is to heat ions by use of an ICRF antenna in the divergent magnetic nozzle. It is found thatby use of a small-sized Laval-type magnetic nozzle, the subsonic flow near the muzzle is convertedto be supersonic through the magnetic Laval nozzle. A fast-flowing plasma is successfully heated byuse of an ICRF antenna in the magnetic beach configuration.

关键词： electric propulsion MPD thruster magnetic nozzle RF ion heating

Free amino acid (FAA) analysis of phloem sap in hybrid rice Shanyou 63 and its parents

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Rice Research Newsletter 2002年第1期10卷 8-9页

作者： Kazushige SOGAWA JIRCAS Makoto hattori National Inst of Agro-Bio Sci Tsukuba305-8686JapanNational Inst of Agro-Bio SciTsukuba305-8686JapanNational Inst of Agro-Bio SciTsukuba305-8686Japan

Hyhrid rice has greatly contributed to rice production inChina. But concurrently a dramatic upsurge of rice plant-hopper occurred, particularly for the whitebacked plant-hopper (WBPH), Sogatella furcifera. It has become animportant economic insect pest of hybrid rice, although ithad only been a minor herbivore of rice before nation-wideexploitation of hybrid rice.

关键词： FAA In analysis of phloem sap in hybrid rice Shanyou 63 and its parents Free amino acid

Prospective real-time evaluation of diagnostic performance using endocytoscopy in differentiating neoplasia from nonneoplasia for colorectal diminutive polyps(≤ 5 mm)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2018年第4期10卷 96-102页

作者： Takahiro Utsumi Yasushi Sano Mineo Iwatate Hironori Sunakawa Akira Teramoto Daizen Hirata Santa hattori Wataru Sano Noriaki Hasuike Kazuhito Ichikawa Takahiro Fujimori Gastrointestinal Center and Institute of Minimally Invasive Endoscopic Care (iMEC) Sano Hospital Department of Pathology Shinko Hospital

AIM To clarify the diagnostic performance of endocytoscopy for differentiation between neoplastic and nonneoplastic colorectal diminutive *** Patients who underwent endocytoscopy between October and December 2016 at Sano Hospital were prospectively recruited. When diminutive polyps(≤5 mm) were detected, the lesions were evaluated by endocytoscopy after being stained with 0.05% crystal violet and 1% methylene blue. The diminutivepolyps were classified into five categories(EC 1 a, 1 b, 2, 3 a, and 3 b). Endoscopists were asked to take a biopsy from any lesion diagnosed as EC1 b(indicator of hyperplastic polyp) or EC2(indicator of adenoma). We have assessed the diagnostic performance of endocytoscopy for EC2 and EC1 b lesions by comparison with the histopathology of the biopsy specimen. RESULTS A total of 39 patients with 63 diminutive polyps were analyzed. All polyps were evaluated by endocytoscopy. The mean polyp size was 3.3 ± 0.9 mm. Among the 63 diminutive polyps, 60 were flat and 3 were pedunculated. The mean time required for EC observation, including the time for staining with crystal violet and methylene blue, was 3.0 ± 1.9 min. Histopathologic evaluation showed that 13 polyps were hyperplastic and 50 were adenomas. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of EC2 for adenoma compared with EC1 b for hyperplastic polyp were 98.0%, 92.3%, 96.8%, 98.0% and 92.3%, respectively. There were only two cases of disagreement between the endoscopic diagnosis made by endocytoscopy and the corresponding histopathological *** Endocytoscopy showed a high diagnostic performance for differentiating between neoplastic and non-neoplastic colorectal diminutive polyps, and therefore has the potential to be used for "real-time histopathology".

关键词： Endocytoscopy Diagnostic performance Diminutive polyp Endocytoscopic classification Realtime histopathology