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Polycyclic aromatic hydrocarbon concentrations, compositions, sources, and associated carcinogenic risks to humans in farmland soils and riverine sediments from Guiyu, China

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Journal of Environmental Sciences 2016年第10期28卷 102-111页

作者： Pengjun Xu Bu Tao Zhiqiang Ye Hu Zhao Yue ren Ting Zhang Yeru Huang Jiping Chen College of Chemistry Dalian University of Technology Dalian 115024 China National Research Center for Environmental Analysis and Measurement Beijing 100029 China Hebei Agricultural University Baoding 071001 China Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China

The concentrations of 16 priority polycyclic aromatic hydrocarbons （PAHs） were measured in 23 farmland soil samples and 10 riverine sediment samples from Guiyu, China, and the carcinogenic risks associated with PAHs in the samples were evaluated. Guiyu is the largest electronic waste （EW） dismantling area globally, and has been well known for the primitive and crude manner in which EWs are disposed, such as by open burning and roasting. The total PAH concentrations were 56-567 ng/g in the soils and 181-3034 ng/g in the sediments. The Shanglian and Huamei districts were found to be more contaminated with PAHs than the north of Guiyu. The soils were relatively weakly contaminated but the sediments were more contaminated, and sediments in some river sections might cause carcinogenic risks to the groundwater system. The PAHs in the soils were derived from combustion sources, but the PAHs in the sediments were derived from both combustion and petroleum sources.

关键词： Polycyclic aromatic hydrocarbonElectronic wasteGuiyuSoilSedimentCarcinogenic risk

Dynamic nanoscale imaging of enriched CO adlayer on Pt(111)confined under h-BN monolayer in ambient pressure atmospheres

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Nano Research 2019年第1期12卷 85-90页

作者： Hao Wu Pengju ren Peng Zhao Zhongmiao Gong Xiaodong Wen Yi Cui Qiang Fu Xinhe Bao Department of Chemical Physics University of Science and Technology of ChinaHefei 230026China State Key Lab of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China National Energy Center for Coal to Clean Fuels Synfuels China Co.LtdBeijing 101400China State Key Laboratory of Coal Conversion Institute of Coal ChemistryChinese Academy of SciencesTaiyuan 030001China Vacuum Interconnected Nanotech Workstation Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China

Fun dame ntal un derstandi ng of chemistry confined to nano space remains a challe nge since molecules en capsulated in confined microe nviron merits are difficult to be ***,we show that CO adsorptio n on Pt(111)8nfined un der mono layer hexago nal boron nitride(h-BN)can be dynamically imaged using near ambient pressure seanning tunneling microscope(NAP-STM)and thanks to tunneling transparency of the top h-BN *** observed CO superstructures on Pt(111)in different CO atmospheres allow to derive surface coverages of CO adlayers,which are higher in the 8nfined nano space between h-BN and Pt(111)than those on the ope n Pt surface un der the same *** NAP-STM imaging data together with theoretical calculations confirm confinement-induced molecule enrichment effect within the 2D nano space,which reveals new chemistry aroused by the confined nano reactor.

关键词： two-dimensional materials confinement effect near ambient pressure scanning tunneling microscope(NAP-STM) molecule enrichment

Characterization, treatment and releases of PBDEs and PAHs in a typical municipal sewage treatment plant situated beside an urban river, East China

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Journal of Environmental Sciences 2013年第7期25卷 1281-1290页

作者： Xiaowei Wang Beidou Xi Shouliang Huo Wenjun Sun Hongwei Pan Jingtian Zhang Yuqing ren Hongliang Liu State Key Laboratory of Water Environment Simulation School of EnvironmentBeijing Normal University State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental Sciences State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental Sciences Department of Chemical and Biochemical engineering Western University State Key Laboratory of Water Environment Simulation School of Environment Beijing Normal University

Characterization, treatment and releases of eight polybrominated diphenyl ethers （PBDEs） congeners and sixteen polycyclic aromatic hydrocarbons （PAHs） in wastewater were evaluated along the treatment processes of a typical secondary treatment municipal sewage treatment plant （STP）（in Hefei City） situated the beside Nanfei River, East China. The findings showed that the average concentrations of the total PBDEs in raw wastewater and treated effluent were 188.578 and 36.884 ng/L respectively. Brominated diphenyl ether （BDE） 209 congener, the predominant PBDE in the STP and Nanfei River, could be related to the discharge of car-industry-derived wastes. For PAHs, the average concentrations in raw wastewater and treated effluent were 5758.8 and 2240.4 ng/L respectively, with naphthalene, benzo[a]pyrene and indeno[1,2,3-c,d]pyrene being detected at the highest concentrations. PAHs mainly originate from the combustion of biomass/coal and petroleum. The STP reduced about 80% of the PBDEs and 61% of the PAHs, which were eliminated mainly by sedimentation processes. The removal rates of PBDEs/PAHs increased with the increase of their solid-water partitioning coefficients. Accordingly, the STP＇s effluent, containing some PBDE congeners （e.g., BDE 47, 99 and 209, etc.） and low-molecular-weight PAHs, could be an important contributor of these contaminants＇ input to Nanfei River. It resulted in a significant increase of PBDE/PAH concentrations and PAH toxicological risk in the river water downstream. About 4.040 kg/yr of PBDEs and 245.324 kg/yr of PAHs could be released into the Nanfei River. The current conventional wastewater treatment processes should be improved to remove the relatively low-molecular-weight PBDEs/PAHs more effectively.

关键词： polybrominated diphenyl ethers polycyclic aromatic hydrocarbons municipal sewage treatment plant urban river

Quantitative and Qualitative Body Traits of Longling Yellow Goats in China

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Agricultural Sciences in China 2010年第3期9卷 408-415页

作者： LEng Jing ZHU ren-jun ZHAO Guo-rong YAng Qing-ran MAO Hua-ming Yunnan Provincial Key Laboratory of Animal and Feed Science Yunnan Agricultural University Kunming 650201 P.R.China Faculty of Food Science and Technology Yunnan Agricultural University Kunming 650201 P.R.China Animal Husbandry Bureau of Longling County Longling 678300 P.R.China

Quantitative, qualitative and phenotypic body measurements were determined on Longling Yellow goats in Longling of Yunnan Province in China. Body weight was determined at birth and then at 3, 6, 9, 12, 18, 24, 36, and 48 mon of age. Body measurements traits including height at wither （HW）, body length （BL）, heart girth （HG）, chest depth （CD）, and circumference of cannon bone （CCB） were determined at 3, 6, 9, 12, 18, 24, 36, and 48 mon of age. Phenotypic traits including coat colour, horns type, tip horn torsion, nose type, hair on forehead, wattles, ear lobes, black back line, hair on legs, and black hair on belly were determined at 12, 18, 24, 36, and 48 mon of age. Males were heavier （P〈0.01 or P〈0.05） than females; and except for chest depth at 24 mon of age （P 〉 0.05）, all other body measurements were also higher （P 〈 0.01 or P 〈 0.05） in males. HW, BL, CD, HG, and BW increased （P 〈 0.01） with age, except for 48 mon of females （P 〉 0.05）; while CCB did not always increase with age. HG had the highest correlation （P〈0.01） with body weights of both sexes. No differences were observed between the two sexes in the colour of the coat, horn type, tip horn torsion, nose type, ear lobes, black back line, and black hair on belly. However, differences exist between the two sexes in the presence of hair on forehead, wattles and long hair on legs. The female goats absence of tip horn torsion had positive effect on all variables measured at 36 and 48 mort of age （P〈0.01 or P〈0.05）. The presence of wattles was associated with heavier body weights from 18 mort （P〈0.01） of age onward, and also with longer HW, BL and CD （P〈0.01 or P〈0.05） in female goats. Female goats with ear lobes had heavier body weights at 12, 36 and 48 mon （P〈0.01） and longer CCB at 12 and 24 mon of ages （P〈0.05）. Hair on legs and black hair on belly only had partly effect body measurements on 12 mon of Longling Yellow female goats. Results of this study provide valuable information that will assist breeder

关键词： Longling Yellow goats body weight body measurements phenotypic characteristics

Elevated serum levels of human relaxin-2 in patients with esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2013年第15期19卷 2412-2418页

作者： Peng ren Zhen-Tao Yu Li Xiu Mei Wang Hua-Min Liu Department of Esophageal Cancer Tianjin Medical University Cancer Institute and Hospital and Key Laboratory of Cancer Prevention and Therapy

AIM: To assess the prognostic value of serum human relaxin 2 (H2 RLN) level in patients with esophageal squamous cell carcinoma (ESCC). METHODS: From October 1998 to September 2009, 146 patients with histopathologically confirmed ESCC were enrolled in this study. One hundred patients underwent en bloc esophagectomy, and 46 patients with unresectable tumors underwent palliative surgery. Five of the 146 patients died of surgical complications. Serum levels of H2 RLN were measured by enzyme linked immunosorbent assay. The relationship between serum H2 RLN level and each of the clinicopathological parameters was analyzed using the χ2 test. Patients were classified into two groups according to their H2 RLN level (ng/mL vs ≥ 0.462 ng/mL). When any analysis cell had fewer than five cases, the Fisher's exact test was used. The statistical difference between groups A and B in each clinicopathological category was determined by the Student's t test (two-tailed) or analysis of variance. Survival curves were plotted using the Kaplan-Meier method. The statistical difference in survival between the different groups was compared using the log-rank test. Survival correlation with the prognostic factors was further investigated by multivariate analysis using the Cox proportional hazards model with backward stepwise likelihood ratio. RESULTS: ESCC patients tended to have significantly higher serum H2 RLN concentrations (0.48 ± 0.17 ng/ mL, n=141) compared with the healthy control group (0.342 ± 0.12 ng/mL, n=112). There was a significant difference between patients with lymph node involvement (0.74 ± 0.15 ng/mL, n=90), distant metastasis (0.90 ± 0.19 ng/mL, n=32) and those without lymph node involvement (0.45 ± 0.12 ng/mL, n=51), and distant metastasis (0.43 ± 0.14 ng/mL, n=109), respectively (P ng/mL) had a poorer prognosis than patients with low serum H2 RLN levels (ng/mL; P=0.0056). The H2 RLN level was also correl

关键词： Esophageal squamous cell carcinoma Re- laxin Tumor markers Metastasis

Kidney function change after transcatheter aortic valve replacement in patients with diabetes and/or hypertension

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2021年第3期22卷 241-247页

作者： Jiaqi FAN Changjie YU Kaida ren Wanbing LIN Stella ng Zexin CHEN Xinping LIN Lihan WAng Qifeng ZHU Yuxin HE Jubo JIAng Xianbao LIU Jian'an WAng Department of Cardiology the Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou310009China Zhejiang University School of Medicine Hangzhou310058China Department of Cardiology Tiantai Country People’s HospitalTaizhou317200China Department of Nephrology the Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou310009China Department of Clinical Epidemiology and Biostatistics the Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou310009China

Aortic stenosis(AS)is a progressive heart valve disease occurring predominantly in older *** to a survey in a western country,the prevalence of AS is nearly 6.4%in patients over 75 years old(Carabello and Paulus,2009).Transcatheter aortic valve replacement(TAVR)is an alternative method for AS *** studies have described how up to 66%of TAVR patients have concomitant baseline kidney dysfunction(Ferro et al.,2015;Gargiulo et al.,2015).The majority of patients can benefit from the TAVR procedure with the recovery of kidney function.

关键词： patients al. Kidney

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原发性纵隔恶性黑色素瘤1例

中华解剖与临床杂志 2024年第8期29卷 566-567页

作者：任东楠孙萌萌徐俊玲轩昂郑州大学人民医院/河南省人民医院核医学科郑州450003

患者女,80岁,因“胸闷、喘息半月”2021年4月27日于河南省人民医院肿瘤内科住院治疗。患者半月前出现胸闷喘息,活动耐量下降,无胸痛、咯血等症状。既往有2型糖尿病病史20年余,口服降糖药,血糖控制情况不详;高血压病史10余年,自述血压控... 详细信息

患者女,80岁,因“胸闷、喘息半月”2021年4月27日于河南省人民医院肿瘤内科住院治疗。患者半月前出现胸闷喘息,活动耐量下降,无胸痛、咯血等症状。既往有2型糖尿病病史20年余,口服降糖药,血糖控制情况不详;高血压病史10余年,自述血压控制可。既往无皮肤病及肿瘤病史,家族无肿瘤相关病史。体格检查:全身皮肤及黏膜未见色素痣、黄染、皮下结节或出血点;右侧锁骨上区可触及肿大淋巴结;左肺叩诊清音、右肺叩诊浊音,呼吸规整,右肺呼吸音低、未闻及明显干湿啰音,无胸膜摩擦音;心脏及腹部检查未见明显异常,双下肢无水肿。肝功能检查:总蛋白51.6 g/L,白蛋白33.7 g/L,球蛋白17.90 g/L,前白蛋白166 mg/L,乳酸脱氢酶530 U/L,α-羟丁酸脱氢酶426 U/L,乳酸脱氢酶同工酶1130 U/L;胸水常规:白细胞计数907×106/L,李凡他试验阳性;肿瘤标志物检查:糖链抗原125(carbohydrate antigen 125,CA125)69.37 U/mL,细胞角蛋白19片段3.64 ng/mL。2021年5月19日胸部CT增强扫描:右前上纵隔见团块状软组织密度影,向前侵入胸壁,向后侵及双侧头臂静脉及上腔静脉,与右肺分界不清,肿块呈轻中度不均匀强化,内可见多发迂曲血管影,胸廓入口处、纵隔内可见多发肿大淋巴结;右侧胸膜弥漫增厚并多发结节影;双侧胸腔积液,右侧较多。见图1A、1B。2021年5月8日行18F-脱氧葡萄糖PET/CT扫描:右上纵隔软组织肿块伴液化坏死,代谢增高,考虑原发恶性病变,建议活检;右侧胸腔及心包积液,右侧胸膜多发结节样增厚伴代谢增高,考虑胸膜转移;肝包膜多发结节伴代谢增高,考虑肝包膜转移。见图1C~1E。2021年5月24日CT引导下纵隔穿刺活检:恶性肿瘤伴局灶坏死;免疫组织化学染色:S-100、HMB45、Melan-A阳性(图1F~1H),符合恶性黑色素瘤诊断。2021年5月19日外周血基因检测:丝/苏氨酸特异性激酶(serine-threonine-threonine protein kinase,BRAF)基因V600E,NRAS和Kissten大鼠肉瘤病毒癌基因同源物基因2、3、4外显子,以及C-KIT和PDGFRA基因均未突变。临床诊断:原发性纵隔恶性黑色素瘤。考虑到患者高龄、基础疾病多,且肿瘤已经发生转移,手术治疗指征不足;基因检测无突变,无靶向治疗适应证,与患者家属沟通后,予以胸腔引流、补充白蛋白等保守治疗。患者症状好转后出院,目前患者失访。

关键词：纵隔肿瘤原发性恶性黑色素瘤转移

沙眼衣原体、淋球菌和解脲脲原体的检测及筛查方法研究进展

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医学检验与临床 2024年第7期35卷 42-46页

作者：李雨欣任鲁风逯素梅田恩源周华誉马鲁豫山东第一医科大学临床与基础医学院山东济南250000 北京中科生仪科技有限公司北京101111 山东第一医科大学第一附属医院(山东省千佛山医院)检验医学科山东济南250014

沙眼衣原体(Chlamydia trachomatis,CT)、淋病奈瑟菌,(Neisseria gonorrhoeae,ng)和解脲脲原体(Ureaplasma urealyticum,UU)是泌尿生殖系统感染常见的病原体,在我国感染率较高且较容易出现混合感染。因此,建立一种能够同时检测这3种病... 详细信息

沙眼衣原体(Chlamydia trachomatis,CT)、淋病奈瑟菌,(Neisseria gonorrhoeae,ng)和解脲脲原体(Ureaplasma urealyticum,UU)是泌尿生殖系统感染常见的病原体,在我国感染率较高且较容易出现混合感染。因此,建立一种能够同时检测这3种病原体的检测方法对降低其传染性及危害性具有重要的临床意义,本文就沙眼衣原体、淋球菌、解脲脲原体的检测方法及筛查方法的研究进展进行概述。

关键词：沙眼衣原体淋病奈瑟菌解脲脲原体核酸检测 POCTs

Minimally invasive surgery vs laparotomy in patients with colon cancer residing in high-altitude areas

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World Journal of Clinical Cases 2021年第35期9卷 10919-10926页

作者： Duo-Ji Suo Lang Yang-Zhen Ci ren Zha-Xi Bian Ba Department of General Surgery People’s Hospital of Tibet Autonomous RegionLasa 850000Tibet Autonomous RegionChina Department of Internal Medicine The Tibet Autonomous Region Centers for Disease Control and PreventionLasa 850000Tibet Autonomous RegionChina

BACKGROUND Colon cancer is associated with a higher incidence among residents in highaltitude *** environment at high altitudes inhibits the phagocytic and oxygen-dependent killing function of phagocytes,thereby increasing the inflammatory factors,inhibiting the body’s innate immunity and increasing the risk of colon *** To examine the effect of minimally invasive surgery vs laparotomy in patients with colon cancer residing in high-altitude *** Ninety-two patients with colon cancer in our hospital from January 2019 to February 2021 were selected and divided into the minimally invasive surgery and laparotomy groups using the random number table method,with 46 patients in each *** invasive surgery was performed in the minimally invasive group and laparotomy in the laparotomy *** conditions,inflammatory index pre-and post-surgery,immune function index and complication probability were *** Operative duration was significantly longer and intraoperative blood loss and recovery time of gastrointestinal function were significantly less(all Prences in serum C-reactive protein,interleukin-6 and tumor necrosis factor-αlevels between the groups,whereas after surgery,the levels were significantly higher in the minimally invasive group(26.98±6.91 mg/L,146.38±11.23 ng/mL and 83.51±8.69 pg/mL vs 41.15±8.39 mg/L,186.79±15.36 ng/mL and 110.65±12.84 pg/mL,respectively,Prences in CD3+,CD4+and CD4+/CD8+levels between the groups,whereas after surgery,the levels decreased in both groups,being significantly higher in the minimally invasive group(55.61%±4.39%,35.45%±3.67%and 1.30±0.35 vs 49.68%±5.33%,31.21%±3.25%and 1.13±0.30,respectively,P<0.05).Complication probability was significant

关键词： Minimally invasive surgery Laparotomy High-altitude area Colon cancer Surgical trauma Immune dysfunction