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Photoacoustic/ultrasound dual-modal imaging of human nails: A pilot study

Journal of Innovative Optical Health Sciences 2024年第6期17卷 15-28页

作者： Yanting Wen Yijie Huang Lin Huang Dan Wu Renbin Zhong shixie jiang Yudi Zhang Ting Liu Xiaotian Liu Huabei jiang Department of Ultrasound Chengdu Fifth People's Hospital Chengdu 611137P.R.China School of Computer Science and Technology Chongqing University of Posts and Telecommunications Chongqing 400065 P.R.China School of Electronic Science and Engineering University of Electronic Science and Technology Chengdu 611731 P.R.China Department of Psychiatry University of Florida College of Medicine GainesvilleFL 32610USA Department of Medical Engineering University of South Florida Tampa 33620USA

Traditional diagnostic techniques including visual examination,ultrasound(US),and magnetic resonance imaging(MRI)have limitations of in-depth information for the detection of nail disorders,resolution,and *** pilot study,for thefirst time,evaluates a dualmodality imaging system that combines photoacoustic tomography(PAT)with the US for the multiparametric quantitative assessment of human *** study involved a small cohort offive healthy volunteers who underwent PAT/US imaging for acquiring the nail unit *** PAT/US dual-modality imaging successfully revealed thefine anatomical structures and microvascular distribution within the nail and nail ***,this system utilized multispectral PAT to analyze functional tissue parameters,including oxygenated hemoglobin,deoxyhemoglobin,oxygen saturation,and collagen under tourniquet and cold stimulus tests to evaluate changes in the microcirculation of the nail *** quantitative analysis of multispectral PAT reconstructed images demonstrated heightened sensitivity in detecting alterations in blood oxygenation levels and collagen content within the nail bed,under simulated different physiological *** pilot study highlights the potential of PAT/US dual-modality imaging as a real-time,noninvasive diagnostic modality for evaluating human nail health and for early detection of nail bed pathologies.

关键词： Nail photoacoustic tomography ultrasound multi-modality quantitative parameter

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Optical neuroimaging:advancing transcranial magnetic stimulation treatments of psychiatric disorders

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Visual Computing for Industry,Biomedicine,and Art 2022年第1期5卷 268-278页

作者： shixie jiang Linda L.Carpenter Huabei jiang Department of Psychiatry and Behavioral Sciences Stanford University School of MedicinePalo Alto CA 94305USA Department of Psychiatry and Human Behavior Butler HospitalAlpert Medical School of Brown UniversityProvidence RI 02903USA Department of Medical Engineering University of South FloridaTampa FL 33613USA

Transcranial magnetic stimulation(TMS)has been established as an important and effective treatment for various psychiatric ***,its effectiveness has likely been limited due to the dearth of neuronavigational tools for targeting purposes,unclear ideal stimulation parameters,and a lack of knowledge regarding the physiological response of the brain to TMS in each psychiatric *** optical imaging modalities,such as functional near-infrared spectroscopy and diffuse optical tomography,are promising tools for the study of TMS optimization and functional targeting in psychiatric *** possess a unique combination of high spatial and temporal resolutions,portability,real-time capability,and relatively low *** this mini-review,we discuss the advent of optical imaging techniques and their innovative use in several psychiatric conditions including depression,panic disorder,phobias,and eating *** further investment and research in the development of these optical imaging approaches,their potential will be paramount for the advancement of TMS treatment protocols in psychiatry.

关键词： Optical imaging Functional near-infrared spectroscopy Diffuse optical tomography Transcranial magnetic stimulation Major depressive disorder Panic disorder Phobia Bulimia nervosa Psychiatric disorders

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