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Role of microRNAs in embryo–endometrial interactions:biological functions and clinical applications

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Reproductive and Developmental Medicine 2023年第4期7卷 238-251页

作者： shiwen qi Suranga P.Kodithuwakku Ronald T.K.Pang Philip C.N.Chiu Mary H.Y.Tang Kai-Fai Lee Department of Obstetrics and Gynaecology School of Clinical MedicineLKs Faculty of MedicineThe University of Hong KongHong Kong SARChina Department of Animal Science Faculty of AgricultureUniversity of PeradeniyaPeradeniya 20400Sri Lanka Shenzhen Key Laboratory of Fertility Regulation The University of Hong Kong-Shenzhen HospitalShenzhenGuangdongChina.

The human endometrium and embryo both produce microRNAs(miRNAs),which are involved in various physiological *** evident suggested that endometrial miRNAs are regulated by steroid hormones that modulate endometrial functions,whereas embryo-derived miRNAs play vital roles in maternal–embryo *** aberrant expression of endometriumor embryo-derived miRNAs can cause early pregnancy and gestational disorders,including repeated implantation failure,recurrent miscarriage,and pathological conditions such as *** are,therefore,ideal candidates for conducting clinicopathological *** diagnostic and prognostic tests using miRNAs are under development;however,the therapeutic applications of miRNAs in regulating gestational disorders require further investigation.

关键词： MicroRNAs Endometrial receptivity Diagnostic biomarkers Therapeutic targets

Magnesium promotes vascularization and osseointegration in diabetic states

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International Journal of Oral Science 2024年第1期16卷 122-133页

作者： Linfeng Liu Feiyu Wang Wei Song Danting Zhang Weimin Lin qi Yin qian Wang Hanwen Li Quan Yuan shiwen Zhang State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&West China Hospital of Stomatology Sichuan UniversityChengduChina State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases&Department of Oral Implantology West China Hospital of StomatologySichuan UniversityChengduChina

Diabetes has long been considered a risk factor in implant therapy and impaired wound healing in soft and hard oral *** has been proved to promote bone healing under normal ***,we elucidate the mechanism by which Mg^(2+)promotes angiogenesis and osseointegration in diabetic *** generated a diabetic mice model and demonstrated thealveolar bone healing was compromised,with significantly decreased *** then developed Mg-coating implants with hydrothermal *** implants successfully improved the vascularization and osseointegration in diabetic ***,Mg^(2+)promoted the degradation of Kelch-like ECH-associated protein 1 (Keap1) and the nucleation of nuclear factor erythroid 2-related factor 2 (Nrf2) by up-regulating the expression of sestrin 2 (SESN2) in endothelial cells,thus reducing theelevated levels of oxidative stress in mitochondria and relieving endothelial cell dysfunction under ***,our data suggested that Mg^(2+)promoted angiogenesis and osseointegration in diabetic mice by regulating endothelial mitochondria metabolism.

关键词： healing diabetic impaired

Effects of zero-valent iron added in the flooding or drainage process on cadmium immobilization in an acid paddy soil

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Journal of Environmental Sciences 2024年第4期138卷 19-31页

作者： Hanbing Meng shiwen Hu Zebin Hong Wenting Chi Guojun Chen Kuan Cheng qiWang Tongxu Liu Fangbai Li Kexue Liu Yang Yang Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640China National-Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and ManagementInstitute of Eco-environmental and Soil SciencesGuangdong Academy of SciencesGuangzhou 510650China School of Resources and Planning Guangzhou Xinhua UniversityGuangzhou 510310China University of Chinese Academy of Sciences Beijing 100049China

Zero-valent iron(ZVI)is a promising material for the remediation of Cd-contaminated paddy ***,the effects of ZVI added during flooding or drainage processes on cadmium(Cd)retention remain ***,Cd-contaminated paddy soil was incubated for 40days of flooding and then for 15 days of drainage,and the underlying mechanisms of Cd immobilization coupled with Fe/S/N redox processes were *** addition of ZVI to the flooding process was more conducive to Cd *** potential available Cd was detected by adding ZVI before flooding,which may be due to the increase in paddy soil pH and newly formed secondary Fe ***,the reductive dissolution of Fe minerals promoted the release of soil colloids,thereby increasing significantly the surface sites and causing Cd ***,the addition of ZVI before flooding played a vital role in Cd retention after soil *** contrast,the addition of ZVI in the drainage phase was not conducive to Cd retention,which might be due to the rapid decrease in soil pH that inhibited Cd adsorption and further immobilization on soil *** findings of this study demonstrated that Cd availability in paddy soil was largely reduced by adding ZVI during the flooding period and provide a novel insight into the mechanisms of ZVI remediation in Cd-contaminated paddy soils.

关键词： Paddy soil Zero-valent iron Cadmium Flooding and drainage Remediation

Friction between Strongly Compressed Polymer Brushes

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Chinese Journal of Polymer Science 2024年第9期42卷 1368-1374,I0008页

作者： qi Liao Institute of Chemistry Chinese Academy of SciencesBejing 100190China

We present the results of molecular dynamics simulations of steady shear between a pair of neutral polymer brushes,as well as a pair of charged polymer brushes in the strongly compressed *** results of the molecular dynamic simulations of neutral and polyelectrolyte brushes in implicit solvent including normal forces,shear forces,viscosities and friction coefficients as a function of separation between brushes,are presented in the *** comparison of the simulation results of neutral and charged brushes shows that the charged brushes is in the quasi-neutral regime,and the dependence of viscosity on the separation distance show the similar power law of neutral *** simulation results confirm that the implicit solvent simulations of polyelectrolyte brushes that ignore hydrodynamics interaction are in agreement with the scaling predictions qualitatively because of screening of hydrodynamic interaction and long-range electrostatic interactions on the correlation length *** of neutral and charged brushes show the lubrication properties that the friction coefficient decreases with the separation decreases at enough large ***,a maximum of friction coefficients is observed for polyelectrolyte brushes,which is in contrast to the neutral brushes with monotonical dependence.

关键词： Polymer brush Frictions coefficient Polyelectrolyte Lubrication

Recent advances in multifunctional shape memory photonic crystals and practical applications

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Nano Research 2024年第1期17卷 79-96页

作者： Yong qi Shufen Zhang State Key Laboratory of Fine Chemicals Frontier Science Center for Smart MaterialsDalian University of TechnologyDalian 116024China

Shape memory photonic crystals(SMPCs)are smart composite materials with changeable structural color integrated by shape memory polymer and photonic *** can produce one or more temporary shapes through nanoscale deformation,memorizing current *** can be recovered to their original shapes or some intermediate states under external stimuli,accompanied by the variation of structural *** porous carriers with built-in sensing properties,SMPCs promoted the interdisciplinary development of nanophotonic technology in materials science,environmental engineering,biomedicine,chemical engineering,and ***,the recent progress on multifunctional SMPCs and practical applications,including traditional and cold programmable SMPCs,is summarized and *** primary concern is shape programming at the nanoscale that has demonstrated numerous attractive functions,including smart sensing,ink-free printing,solvent detection,reprogrammable gradient wetting,and controllable bubble transportation,under variations of the surface *** aims to figure out the nanoscale shape memory effects on structural color conversion and additional performance,inspiring the fabrication of the next generation of ***,perspectives on future research directions and applications are also *** is believed that multifunctional SMPCs are powerful nanophotonic tools for the interdisciplinary development of numerous disciplines in the future.

关键词： photonic crystal shape memory structural color cold programmable shape recovery

Geometric Constraints for Global Regularity of 3D Shear Thickening Fluids

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 205-210页

作者： Jia-qi Yang Research&Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen518063China Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing100190China

We consider the relation between the direction of the vorticity and the global regularity of 3D shear thickening *** is showed that a weak solution to the non-Newtonian incompressible fluid in the whole space is stron... 详细信息

关键词： direction of the vorticity non-Newtonian fluid global regularity

Understanding the spatial interaction of ultrasounds based on three-dimensional dual-frequency ultrasonic field numerical simulation

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China Foundry 2024年第1期21卷 29-43页

作者： Zhao-yang Yin qi-chi Le Yan-chao Jiang Da-zhi Zhao qi-yu Liao qi Zou Key Lab of Electromagnetic Processing of Materials Ministry of EducationNortheastern UniversityShenyang 110819China School of Materials Science and Engineering Northeastern UniversityShenyang 110819China

A transient 3D model was established to investigate the effect of spatial interaction of ultrasounds on the dual-frequency ultrasonic field in magnesium alloy *** effects of insertion depth and tip shape of the ultrasonic rods,input pressures and their ratio on the acoustic field distribution were discussed in ***,the spacing,angle,and insertion depth of two ultrasonic rods significantly affect the interaction between distinct *** a result,various acoustic pressure distributions and cavitation regions are *** spherical rods mitigate the longitudinal and transversal attenuation of acoustic pressure and expand the cavitation volume by 53.7%and 31.7%,respectively,compared to the plate and conical *** the input pressure will enlarge the cavitation region but has no effect on the acoustic pressure distribution *** acoustic pressure ratio significantly affects the pressure distribution and the cavitation region,and the best cavitation effect is obtained at the ratio of 2:1(P15:P20).

关键词： dual-frequency ultrasonic numerical model acoustic pressure spatial interaction magnesium alloy

Adaptive sampling for corrugated plate digitization using a laser displacement sensor

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Science China(Technological Sciences) 2024年第5期67卷 1510-1523页

作者： WU ChengXing qi qi CHEN BaiJin YANG JiXiang DING Han State Key Laboratory of Intelligent Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan430074China State Key Laboratory of Intelligent Manufacturing Equipment and Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan430074China

The surface quality of a corrugated plate directly determines the heat transfer property of the thermal power mechanical *** detection methods are impractical for real-world production,being slow and *** contrast,the point laser displacement sensor,employing the optical triangle method,emerges as a promising device for assessing parts with variable curvature and highly reflective *** its benefits,high-density sampling by an innate frequency introduces challenges such as data redundancy and a poor signal-to-noise ratio,potentially affecting the efficiency and precision of subsequent data *** address these challenges,adjustable frequency data sampling has been developed for this sensor,allowing adaptive sampling for corrugated plate *** process begins with surface digitization to extract discrete points,which are transformed into intersection curves using the B-spline fitting ***,dominant points are identified,considering multigeometric constraints for curvature and arch ***,the sampling signal is adjusted based on the distribution information of dominant *** results indicate that the proposed method effectively minimizes redundant sampling without compromising the accurate capture of essential geometric features.

关键词： corrugated plate laser displacement sensor adaptive sampling dominant point curvature arch height

Cosmological Constraints on Neutrino Masses in Light of JWST Red and Massive Candidate Galaxies

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Research in Astronomy and Astrophysics 2024年第4期24卷 7-12页

作者： Jian-qi Liu Zhi-qi Huang Yan Su School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China CSST Science Center for the Guangdong-Hong Kong-Macao Greater Bay Area Zhuhai 519082China

The overabundance of the red and massive candidate galaxies observed by the James Webb Space Telescope(JWST)implies efficient structure formation or large star formation efficiency at high redshift z~*** the scenario of a low or moderate star formation efficiency,because massive neutrinos tend to suppress the growth of structure of the universe,the JWST observation tightens the upper bound of the neutrino *** A cold dark matter cosmology and a star formation efficiency∈[0.05,0.3](flat prior),we perform joint analyses of Planck+JWST and Planck+BAO+JWST,and obtain improved constraints∑m_(ν)<0.196 eV and ∑m_(ν)+<0.111 eV at 95% confidence level,*** on the above assumptions,the inverted mass ordering,which implies ∑m_(ν)≥0.1 eV,is excluded by Planck+BAO+JWST at 92.7% confidence level.

关键词： (cosmology:)cosmological parameters galaxies:abundances galaxies:formation neutrinos