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A cross-sectional study on compliance with topical glaucoma medication and its associated socioeconomic burden for a Chinese population

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International Journal of Ophthalmology(English edition) 2017年第2期10卷 293-299页

作者： Man-Hin Lui Jason Chun Ho lam Yi Lee Kwong Tak Siu Wong Pak Long Cheung Sherri Shun Yan Lai Pak Lun Yuen Wai Yiu lam Ho Yan Chan Yiu Fai Wong Jimmy shiu Ming Lai Kendrick Co Shih Li Ka Shing Faculty of Medicine the University of Hong KongPokfulamHong KongChina Department of Ophthalmology Li Ka Shing Faculty of Medicinethe University of Hong KongPokfulamHongKongChina Department of Ophthalmology Queen Mary HospitalPokfulamHong KongChina

AIM： To estimate the overall drug compliance for local Chinese glaucoma patients on long-term topical ***： This was a retrospective cross-sectional ***-seven primary glaucoma patients from the subspecialty clinic of a publicly-funded tertiary care hospital in Hong Kong completed a questionnaire on compliance with topical glaucoma medication,attitude towards glaucoma and therapy and vision related quality of *** was defined as reporting missing more than or equal to 10% of the prescribed topical glaucoma medication during the 2wk immediately prior to the *** between noncompliance and demographics,attitude,disease and treatment status was *** was estimated with quality of life and direct medical cost involved with *** logistic regression on noncompliance was performed on selected ***： Compliance was calculated as 75%（95% CI： 64%-87%） among 57 subjects（mean age 69 y,female 51%）.No statistical significant relationship was established between noncompliance and any single factors or ***（P=0.048） and forgetfulness（P=0.064） were found to be marginally significant predictive factors on noncompliance in multivariable logistic *** might be related（P=0.130） to poorer self-rated vision-associated quality of *** societal cost of noncompliance was estimated to be over 2510 life-years and US$ 3.7 million ***： The compliance of Chinese glaucoma patients in Hong Kong is comparable to other parts in the world,and carries detrimental impacts on individual and societal *** and forgetfulness are two possible independent predictors for noncompliance.

关键词： glaucoma eye drop compliance quality of life

Theoretical study of substituent effect on the charge mobility of 2,5-bis(trialkylsilylethynyl)-1,1,3,4-tetraphenylsiloles

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Science China Chemistry 2010年第11期53卷 2311-2317页

作者： lam Jacky Wing Yip Department of Chemistry The Hong Kong University of Science & Technology

The theoretical calculation of the charge mobility of 2,5-bis(trialkylsilylethynyl)-1,1,3,4-tetraphenylsiloles is presented.B3LYP/6-31* calculations demonstrated that these silole molecules possessed large coupling matrix elements and reorganization energies for electron and hole transfers and high electron *** bulkiness of the trialkyl substituents influenced the charge mobility of the silole molecules,with the smaller trimethyl group imparting higher charge mobility than triethyl and triisopropyl substituents.

关键词： silole theoretical calculation substitution effect electronic structure charge mobility

Environmental threats to the Three Gorges Reservoir Region:Are mutagenic and genotoxic substances important?

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Journal of Environmental Sciences 2015年第12期27卷 172-174页

作者： Paul K.S.lam State Key Laboratory in Marine Pollution Department of Biology and ChemistryCity University of Hong Kong

The Three Gorges Dam project（TGDP）,with a total static investment of 95.46 billion RMB（US$10.97 billion）based on the 1993 price level,commenced in 1994 and was completed in *** creation of the Three Gorges Reservoir following the completion of the TGDP had brought about significant changes to the Three Gorges Reservoir Region（TGRR）,stretching from the town of Sandouping in Hubei Province to the Jiangjin District of Chongqing *** TGDP has led to progressive urbanization and industrialization of the TGRR,accompanied by increased shipping activities,greater

关键词： Three Gorges Dam Persistent organic pollutants Yangtze River Sediment Water

Online hybrid test using a finite element program and an explicit integration scheme

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Science China(Technological Sciences) 2015年第1期58卷 163-173页

作者： Alexandre lam PAN Peng DENG KaiLai Department of Civil Engineering Tsinghua University Key Laboratory of Civil Engineering Safety and Durability of China Education Ministry Department of Civil Engineering Tsinghua University

A new online hybrid test system combined with substructuring techniques and incorporating finite element methods is *** the proposed system,numerical substructure analysis is conducted by ABAQUS/*** ABAQUS user subroutine is used as the interface between the main control program and ABAQUS to impose the target displacements and determine the reaction *** iteration is needed in this system,making it suitable for physical *** the approach also avoids the need to modify source code,it will be appealing to a number of real engineering *** proposed system adopts a separated-model framework,operator-splitting integration scheme,and data exchange through a socket *** earthquake responses of a simple steel moment-resisting frame are simulated,and the results obtained from the new system are compared to those obtained from the conventional *** is found that the results obtained from the new system are accurate,demonstrating the applicability and efficiency of the proposed *** optimal test parameters are also studied to gain the most accurate results in the minimum time.

关键词： online hybrid test substructuring ABAQUS/Explicit separated-model framework operator-splitting method

Finite-Time Fuzzy Sliding Mode Control for Nonlinear Descriptor Systems

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IEEE/CAA Journal of Automatica Sinica 2021年第6期8卷 1141-1152页

作者： Zhixiong Zhong Xingyi Wang Hak-Keung lam Key Laboratory of Information Processing and Intelligent Control Minjiang UniversityFuzhou 350121China College of Mechanical and Electronic Engineering Fujian Agriculture and Forestry UniversityFuzhou 350108China Department of Engineering King’s College LondonLondonWC2R 2LSUnited Kingdom

This article addresses the finite-time boundedness(FTB)problem for nonlinear descriptor ***,the nonlinear descriptor system is represented by the Takagi-Sugeno(T-S)model,where fuzzy representation is assumed to be appearing not only in both the state and input matrices but also in the derivative *** using a descriptor redundancy approach,the fuzzy representation in the derivative matrix is reformulated into a linear ***,we introduce a fuzzy sliding mode control(FSMC)law,which ensures the finite-time boundedness(FTB)of closed-loop fuzzy control systems over the reaching phase and sliding motion ***,by further employing the descriptor redundancy representation,the sufficient condition for designing FSMC law,which ensures the FTB of the closed-loop control systems over the entire finite-time interval,is derived in terms of linear matrix inequalities(LMIs).Finally,a simulation study with control of a photovoltaic(PV)nonlinear system is given to show the effectiveness of the proposed method.

关键词： Finite-time boundedness(FTB) fuzzy sliding mode control(FSMC) Takagi-Sugeno(T-S)fuzzy descriptor system

社区居家老年人跌倒经历的体验:质性研究的meta整合

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International Journal of Nursing Sciences 2024年第2期11卷 276-285页

作者：江慧悯袁浩斌 Stephen TEE 林爱贞 Faculty of Health Sciences and Sports Macao Polytechnic UniversityMacaoChina Faculty of Health and Social Sciences Bournemouth UniversityBournemouthEnglandUK

目的系统评价和整合社区居家老年人跌倒经历的看法与体验,为后续发展跌倒预防及管理的干预提供信息,为健康照护实践提供建议。方法依据乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)质性系统评价方法论进行质性研究meta整合,在Pub... 详细信息

目的系统评价和整合社区居家老年人跌倒经历的看法与体验,为后续发展跌倒预防及管理的干预提供信息,为健康照护实践提供建议。方法依据乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)质性系统评价方法论进行质性研究meta整合,在PubMed、CINAHL、PsycInfo、Embase、Web of science等数据库进行检索,发表时间限定为2010年1月至2023年5月,仅纳入经同行评审的英文文献。使用JBI质性研究质量评价标准评价纳入文献的方法学质量,按照ConQual评分准则检验整合结果的信度。本综述方案已在PROSPERO注册(CRD 42023421789)。结果共纳入10项研究,方法学质量评价得分为60%至90%。提炼59个完好明确的结果,将相似结果归纳组合形成7个类别,并综合成3个整合结果,在ConQual评分上,综合结果2评为中等,综合结果1和3评为低等。整合结果1:跌倒后老年人经历了身体的损伤和疼痛、日常活动受限、社交受限、独立性降低或丧失、并有恐惧和无助感。整合结果2:经历跌倒后,老年人反思跌倒的原因,并识别、解释风险因素。整合结果3:老年人对跌倒原因和后果有正面和负面的看法,其采取的应对跌倒的措施包括使用辅助器具、纠正风险因素、寻求医疗帮助、关注身体和心理状况等。结论医疗卫生提供者应重视老年人跌倒后的感受、经历,以及对跌倒原因和影响的反思,进行特定的干预。今后还需要进行纵向研究,以检测跌倒对老年人的长期影响,深入了解他们的反思、感知、态度和预防行为随时间的改变情况。

关键词：老年人社区经历跌倒观点系统综述

Liouvillian Solutions of Algebraic Ordinary Differential Equations of Order One of Genus Zero

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Journal of Systems Science & Complexity 2023年第2期36卷 884-893页

作者： NGUYEN Tri Dat NGO lam Xuan Chau Faculty of Basic Science Ho Chi Minh City University of TransportHo Chi Minh CityVietnam Department of Mathematics and Statistics Quy Nhon UniversityQuy Nhon CityVietnam

This paper considers the class of autonomous algebraic ordinary differential equations(AODEs)of order one,and studies their Liouvillian general *** particular,let F(y,w)=0 be a rational algebraic curve over *** authors give necessary and sufficient conditions for the autonomous first-order AODE F(y,y′)=0 to have a Liouvillian solution over ***,the authors show that a Liouvillian solutionαof this equation is either an algebraic function over C(x)or an algebraic function over C(exp(ax)).As a byproduct,these results lead to an algorithm for determining a Liouvillian general solution of an autonomous AODE of order one of genus *** parametrizations of rational algebraic curves play an important role on this method.

关键词： Algebraic ordinary differential equation autonomous differential equation Liouvillian solution rational algebraic curve rational parametrizations

Building an e-Portfolio with a learning plan centric approach

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Journal of Zhejiang University-Science C(Computers and Electronics) 2012年第1期13卷 37-47页

作者： lam-for KWOK Ka-shing CHAN Department of Computer Science City University of Hong Kong

A portfolio records achievements in the personal growth process. A personal development e-Portfolio assists an individual in planning his/her development path and reflecting upon his/her own learning. In this article, we propose an approach to constructing a personal development portfolio. An abstract information model is presented to support such a portfolio. The information model is proposed based upon and according to IMS standards. The use of this approach is illustrated by way of a prototype e-Portfolio system. The usage scenario and limitations of such a portfolio are also discussed.

关键词： E-Portfolio Educational technology system Lifelong learning

Multiomics approaches to uncover endometrial receptivity in embryo implantation:a mini-review

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Reproductive and Developmental Medicine 2024年第3期8卷 178-185页

作者： Sudini R.Fernando Yang Yan Manish kumar Hoi-lam Lai Yin-Lau Lee Ernest H.Y.Ng William S.B.Yeung Kai-Fai Lee Department of Obstetrics and Gynaecology Li Ka Shing Faculty of MedicineThe University of Hong KongPokfulamHong Kong SAR 999077China Department of Animal Science Faculty of Animal Science and Export AgricultureUva Wellassa UniversityBadullaSri Lanka Shenzhen Key Laboratory of Fertility Regulation The University of Hong Kong-Shenzhen HospitalFutian DistrictShenzhen 518053China

Successful implantation requires concerted interactions during the apposition,adhesion,and invasion of the embryo into a receptive ***,the embryo implantation rate for assisted reproduction remains low despite the transfer of good quality *** in endometrial transcriptomics,proteomics,lipidomics,and even microbiota all play important roles in embryo ***,the expression of steroid hormone-regulated adhesive and anti-adhesive molecules during the embryo implantation window is becoming an area of increasingly intense *** review(a)summarizes the different molecules expressed in the receptive endometrium and(b)proposes the use of surface protein markers to predict pregnancy outcomes from assisted reproduction.

关键词： Cell surface proteins Steroid regulation Endometrial receptivity Receptivity marker Infertility