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World Journal of Stem Cells 2021年第8期13卷 1151-1159页

作者： Hyunjun Ahn Sang Yeon lee Won ju jung Kye-Ho lee bio Beauty&Health Company(bBHC)-Stem Cell Treatment&Research Institute(STRI) Seoul 04420South Korea 97.7 Beauty&Health(B&H)Clinics Seoul 04420South Korea

BACKGROUND Stroke is one of the major causes of disability and death *** treatments for stroke exist,but existing treatment methods have limitations such as difficulty in the regeneration of damaged neuronal cells of the ***,mesenchymal stem cells(MSCs)have been studied as a therapeutic alternative for stroke,and various preclinical and case studies have been *** SUMMARY A 55-year-old man suffered an acute stroke,causing paralysis in the left upper and lower *** intravenously transplanted the minimally manipulated human umbilical cord-derived MSCs(MM-UC-MSCs)twice with an 8-d *** 65 wk after transplantation,the patient returned to his previous occupation as a veterinarian with no adverse *** MM-UC-MSCs transplantation potentially treats patients who suffer from acute ischemic stroke.

关键词： Acute ischemic stroke Behavioral disorder Umbilical cord-derived mesenchymal stem cells Allogenic Cell therapy Minimal manipulation Case report

Sex hormone-binding globulin impedes hepatocellular carcinoma growth via MERTK regulation

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Genes & Diseases 2022年第3期9卷 579-581页

作者： Sang R.lee Eui-ju Hong College of Veterinary Medicine Chungnam National UniversityDaejeon 34134Republic of Korea

Sex hormone-binding globulin(SHBG),a crucial modulator of sex steroids in human blood,regulates androgen bioavailability and homeostasis.1 When androgen or AR signaling is known to be involved in the hepatocellular carcinoma(HCC)and SHBG plays an integral role in regulating the levels of bioavailable androgens,the concern whether SHBG might influence HCC onset or progression by modulating androgen action remains open.

关键词： globulin hepatocellular homeostasis

Alopecia treatment using minimally manipulated human umbilical cord-derived mesenchymal stem cells:Three case reports and review of literature

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World Journal of Clinical Cases 2021年第15期9卷 3741-3751页

作者： Hyunjun Ahn Sang Yeon lee Won ju jung Kye-Ho lee bio Beauty&Health Company(bBHC)-Stem Cell Treatment&Research Institute(STRI) Seoul 04420South Korea Department of Functional Genomics University of Science and Technology KRIBB SchoolDeajeon 34113South Korea 97.7 Beauty&Health(B&H)Clinics Seoul 04420South Korea

BACKGROUND Alopecia areata(AA)is a common autoimmune disease characterized by hair *** appears in extensive forms,such as progressive and diffusing hair loss(diffuse AA),a total loss of scalp hair(alopecia totalis),and complete loss of hair over the entire body(alopecia universalis).Recently,mesenchymal stem cells(MSCs)have been identified as a therapeutic alternative for autoimmune *** this reason,preclinical and case studies of AA and related diseases using MSCs have been *** SUMMARY Case 1:A 55-year-old woman suffered from AA in two areas of the *** was given 15 rounds of minimally manipulated umbilical cord-MSCs(MM-UC-MSCs)over 6 *** AA gradually improved 3 mo after the first *** patient was cured,and AA did not *** 2:A 30-year-old woman,with history of local steroid hormone injections,suffered from AA in one area on the *** was given two rounds of MM-UC-MSCs over 1 *** AA immediately improved after the first *** patient was cured,and AA did not *** 3:A 20-year-old woman,who was diagnosed with alopecia universalis at the age of 12,was given 14 rounds of MM-UC-MSCs over 12 *** hair began to grow about 3 mo after the first *** patient was cured,and alopecia universalis did not *** MM-UC-MSC transplantation potentially treats patients who suffer from AA and related diseases.

关键词： Alopecia areata Umbilical cord-derived mesenchymal stem cells Allogenic Cell therapy Minimal manipulation Case report

Antistatic coating material consisting of poly (butylacrylate-co-styrene) core-nickel shell particle

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中国有色金属学会会刊：英文版 2009年第B09期19卷 119-123页

作者： Min-Yeong JEONG Byung-Yoon AHN Sang-Koul lee Won-Ki lee Nam-ju JO Department of Polymer Science and Engineering Pusan National University Kumho Petrochemical Samsung Corning Precision Glass Division of Chemical Engineering Pukyong National University

A transparent and antistatic coating material consisting of polymer core-metal shell particle was prepared. As a polymer core, poly(butylacrylate-co-styrene)s ([P(BA-co-sty)s]) with various compositions of butylacrylate and styrene were synthesized by emulsion polymerization. And the effect of comonomer composition on the thermal property of polymer core particle was investigated. By electroless plating method, the nickel particles were formed and deposited on the surface of P(BA-co-Sty) particles to form P(BA-co-Sty) core-nickel shell composite particles. SEM observation confirms that the nickel particles with size of 15 nm are distributed on the surface of the polymer core particles. The surface resistance of P(BA-co-Sty) core-nickel shell composite is 0.8×108Ω/cm2, enough to act as antistatic coating material.

关键词：复合粒子涂层材料单体组成抗静电苯乙烯丁酯聚合物颗粒镍

Polyaniline and multi-walled carbon nanotube composite electrode for rechargeable battery

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中国有色金属学会会刊：英文版 2012年第S3期22卷 717-721页

作者： Yu-Jeong LIM Min-Young PARK Sang-Keol lee Won-Ki lee Nam-ju JO Department of Polymer Science & Engineering Pusan National University Hankook Tire Co.Ltd. Department of Polymer Engineering Pukyong National University

The multi-walled carbon nanotube was introduced into the polymer matrix (PANI) to improve the electric conductivity as well as mechanical properties of the original polymer ***/multi-walled carbon nanotube (MWCNT) composites were synthesized via ex-situ and in-situ polymerization to improve their electrical *** the DC conductivities of PANI/MWCNT according to content and diameter of MWCNT were measured by four-point *** highest electric conductivity of PANI/MWCNT composite is 20 S/cm when 0.3% (mass fraction) MWCNTs with 10 nm in diameter and 15 μm in length are added in composite.

关键词： polymer electrode electric conductivity multi-walled carbon nanotube conducting polymer

A new approach to stability analysis of neural networks with time-varying delay via novel Lyapunov-Krasovskii functional

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Chinese Physics B 2010年第5期19卷 115-120页

作者： S.M.lee O.M.Kwon ju H.Park Department of Electronic Engineering Daegu UniversityGyungsanGyungbuk 712-714Republic of Korea College of Electrical and Computer Engineering 410 SungBong-RoHeungduk-GuChungbuk National UniversityCheongju 361-763Republic of Korea Nonlinear Dynamics Group Department of Electrical EngineeringYeungnam University214-1 Dae-DongKyongsan 712-749Republic of Korea

In this paper, new delay-dependent stability criteria for asymptotic stability of neural networks with time-varying delays are derived. The stability conditions are represented in terms of linear matrix inequalities （LMIs） by constructing new Lyapunov-Krasovskii functional. The proposed functional has an augmented quadratic form with states as well as the nonlinear function to consider the sector and the slope constraints. The less conservativeness of the proposed stability criteria can be guaranteed by using convex properties of the nonlinear function which satisfies the sector and slope bound. Numerical examples are presented to show the effectiveness of the proposed method.

关键词： neural networks Lyapunov-Krasovskii functional sector bound time-delay

Synchronization of chaotic Lur'e systems with delayed feedback control using deadzone nonlinearity

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Chinese Physics B 2011年第1期20卷 209-214页

作者： S.M.lee O.M.Kwon ju H.Park Department of Electronic Engineering Daegu UniversityGyungsan 712-714Republic of Korea School of Electrical Engineering Chungbuk National University410 SungBong-RoHeungduk-guCheongju 361-763Republic of Korea Department of Electrical Engineering Yeungnam University214-1 Dae-DongKyongsan 712-749Republic of Korea

In this paper we present a synchronization method for chaotic Lur＇e systems by constructing a new piecewise Lyapunov function. Using a delayed feedback control scheme, a delay-dependent stability criterion is derived for the synchronization of chaotic systems that are represented by Lur＇e systems with deadzone nonlinearity. Based on the Lyapunov-Krasovskii functional and by using some properties of the nonlinearity, a new delay-dependent stabilization condition for synchronization is obtained via linear matrix inequality （LMI） formulation. The criterion is less conservative than existing ones, and it will be verified through a numerical example.

关键词： Lur'e systems synchronization deadzone linear matrix inequality

Biomass growth characteristics of 13-year-old Pinus densiflora *** *** a post-fire plantation on different contour conditions in Samcheuk,Korea

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Journal of Mountain Science 2016年第7期13卷 1238-1244页

作者： lee ju-Hyoung lee Do-Hyung Kim Do-Hyun Park Jin-Hwa KimJae-Hee Department of Forest Resources Yeungnam UniversityGyeongsan 712-749Republic of Korea Useful Plant Resources Center Korea National ArboretumYangpgeong-gun 12519Republic of Korea Korea Forest Welfare Institute Therapy-ro 209Bonghyeon-myeonYeongju-siGyeongsangbuk-doRepublic of Korea Department of forest genetic resources National Institute of Forest Science57HoegiroDongdaemun-guSeoul 02455Republic of Korea

We used preliminary data to estimate the growth volume of artificially reforested Pinus densiflora in a post-fire area on three different contour conditions. We compared the growth of P. densiflora on a south-facing slope(Ssth), north-facing slope(Snth) and ridge area(Ridge), using 7 trees selected from each stand aspect. The tree height, diameter and growth volume were measured and the dry weight of each plant part were compared and analyzed. The results revealed that the total dry weight was highest on Ssth(5992.3 g), followed by Snth(4833.2 g) and lowest on Ridge(3160.1 g). The height growth was highest on Snth(285.8 cm), followed by Ssth(274.5 cm) and lowest on Ridge(211.5 cm). The diameter growth was greatest on Ssth(7.37 cm), followed by Snth(7.10 cm) and lowest on Ridge(5.72 cm). The volume growth was highest on Ssth(4257.7 cm3), followed by Snth(3750.7 cm3) and lowest on Ridge(2093.7 cm3). Therefore, we should consider and include the concept of slope orientation together with differences in habitat environments in afforestation projects when creating artificial forests with P. densiflora. These study results can serve as important preliminary data for future establishment of artificial forest of P. densiflora in a post-fire plantation.

关键词： Pinus densiflora Growth characteristics Contour conditions Planted stand Post-fire plantation

Measuring the spatial and social characteristics of the architectural plans of aged care facilities

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Frontiers of Architectural Research 2017年第4期6卷 431-441页

作者： ju Hyun lee Michael J. Ostwaid Hyunsoo lee School of Architecture and Built Environment The University of Newcastle Callaghan NSW 2308 Australia Department of Interior Architecture and Built Environment Yonsei University Seoul 03722 Republic of Korea

This paper presents a method that combines visibility graph and isovist analyses to investigate the spatia[ and social properties of architectural plans for aged care facilities. The potential of the combined method is examined by measuring the properties of three sets of plans for residential aged care facilities. The first set is a pair of hypothetical, idealized plans, which allegedly reflect the ＂best practice＂ in the industry. The second set comprises a pair of plans for recent Australian designs, and the third set is a pair of plans for South Korean facilities. Results of the computational anatysis of these six plans suggest that social and cultural factors may shape the design of aged care settings and partially explain their international differences. The application of this methodological approach contributes to the understanding of the relation- ship between spaces and their cultural and social properties in the design of aged care facitities.

关键词： Visibitity graph anaty-sis (VGA) Space Syntax Aged care facility Isovist property Sociocutturalcharacteristics

HOS1 Facilitates the Phytochrome B-Mediated Inhibition of PIF4 Function during Hypocotyl Growth in Arabidopsis

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Molecular Plant 2017年第2期10卷 274-284页

作者： ju-Heon Kim Hyo-jun lee Jae-Hoon jung Sangmin lee Chung-Mo Park Department of Chemistry Seoul National University Seoul 08826 Korea Sainsbury Laboratory University of Cambridge Cambridge CB2 1LR UK Plant Genomics and Breeding Institute Seoul National University Seoul 08826 Korea These authors contributed equally to this article Present address: SK Innovation Daejeon 34124 Korea

Upon exposure to light, developing seedlings undergo photomorphogenesis, as illustrated by inhibition of hypocotyl elongation, cotyledon opening, and leaf greening. During hypocotyl photomorphogenesis, light signals are sensed by multiple photoreceptors, among which the red/far-red light-sensing phytochromes have been extensively studied. However, it is not fully understood how the phytochromes modulate hypo- cotyl growth. Here, we demonstrated that HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 （HOS1）, which is known to either act as E3 ubiquitin ligase or affect chromatin organization, inhibits the transcriptional activation activity of PHYTOCHROME INTERACTING FACTOR 4 （PIF4）, a key transcrip- tion factor that promotes hypocotyl growth. Consistent with the negative regulatory role of HOSl in hypo- cotyl growth, HOSl-defective mutants exhibited elongated hypocotyls in the light. Notably, phyB induces HOS1 activity in inhibiting PIF4 function. Taken together, these observations provide a molecular basis for the phyB-mediated suppression of hypocotyl growth in Arabidopsis.

关键词： photomorphogenesis hypocotyl growth phytochrome signaling HOS1 PIF4