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Photonics Research 2024年第8期12卷 1681-1688页

作者： RUI TANG SHUHEI OHNO KEN TANIZAWA KAZUHIRO IKEDA MAKOTO OKANO KASIDIT TOPRASERTPONG shinichi TAKAGI MITSURU TAKENAKA Department of Electrical Engineering and Information Systems The University of TokyoTokyo 113-8656Japan Quantum ICT Research Institute Tamagawa UniversityTokyo 194-8610Japan National Institute of Advanced Industrial Science and Technology Ibaraki 305-8568Japan

Photonic integrated circuits are emerging as a promising platform for accelerating matrix multiplications in deep learning,leveraging the inherent parallel nature of *** various schemes have been proposed and demonstrated to realize such photonic matrix accelerators,the in situ training of artificial neural networks using photonic accelerators remains challenging due to the difficulty of direct on-chip backpropagation on a photonic *** this work,we propose a silicon microring resonator(MRR)optical crossbar array with a symmetric structure that allows for simple on-chip backpropagation,potentially enabling the acceleration of both the inference and training phases of deep *** demonstrate a 4×4 circuit on a Si-on-insulator platform and use it to perform inference tasks of a simple neural network for classifying iris flowers,achieving a classification accuracy of 93.3%.Subsequently,we train the neural network using simulated on-chip backpropagation and achieve an accuracy of 91.1%in the same inference task after ***,we simulate a convolutional neural network for handwritten digit recognition,using a 9×9 MRR crossbar array to perform the convolution *** work contributes to the realization of compact and energy-efficient photonic accelerators for deep learning.

关键词： resonator neural matrix

Relationship between Nonexercise Activity Thermogenesis and Calf Circumference in Older Women

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Open Journal of Therapy and Rehabilitation 2024年第3期12卷 213-223页

作者： Michio Wachi Takumi Jiroumaru Mika Suzuki shinichi Noguchi Ayako Satonaka Department of Physical Therapy Bukkyo University Kyoto City Japan Department of Physical Therapy Biwako Professional University of Rehabilitation Higashiomi City Japan Graduate School of Medicine Nagoya University Nagoya City Japan Faculty of Health and Medical Science Aichi Syukutoku University Nagakute City Japan

Purpose: Frailty is a state of declined vitality of the body and mind with age in which life functions are impaired. In addition, there is a difference in the susceptibility of older women to frailty compared with that of older men. Therefore, assessing and encouraging physical activity in older adults before they become frail is essential. We aimed to clarify the relationship between calf circumference and body composition and assess the potential association between calf circumference and physical activity indices in older women. Methods: This cross-sectional study included 18 healthy older adults (age 69.0 ± 5.7 years). The physical characteristics, calf circumference, body composition, calf muscle thickness, and physical activity questionnaire that included items on exercise-related activity thermogenesis (EAT) and nonexercise activity thermogenesis (NEAT) were assessed. The association between calf circumference and these additional measures was examined. Results: Positive and significant correlations were found between the calf circumference and body weight, body mass index (BMI), skeletal muscle mass, skeletal muscle mass index, calf muscle thickness, total questionnaire score, and NEAT score (r = 0.66 - 0.87). However, no significant correlations were observed between the calf circumference and EAT scores. Conclusion: Calf circumference in older women may reflect NEAT activity. Improving NEAT activity is an important health-promoting factor in older women.

关键词： Nonexercise Activity Thermogenesis Frailty Calf Circumference Older Women

Giant Brunner's gland hyperplasia of the duodenum successfully resected en bloc by endoscopic mucosal resection: A case report

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World Journal of Gastrointestinal Endoscopy 2024年第6期16卷 368-375页

作者： Makomo Makazu Akiko Sasaki Chikamasa Ichita Chihiro Sumida Takashi Nishino Miki Nagayama shinichi Teshima Gastroenterology Medicine Center Shonan Kamakura General HospitalKamakura 247-8533Japan Department of Gastroenterology Shonan Kamakura General HospitalKanagawa 247-8533Japan Department of Pathology Shonan Kamakura General HospitalKamakura 247-8533Japan

BACKGROUND Duodenal Brunner's gland hyperplasia(BGH)is a therapeutic target when complications such as bleeding or gastrointestinal obstruction occur or when malignancy cannot be ruled ***,we present a case of large BGH treated with endoscopic mucosal resection(EMR).CASE SUMMARY An 83-year-old woman presented at our hospital with *** tests revealed severe anemia,esophagogastroduodenoscopy showed a 6.5 cm lesion protruding from the anterior wall of the duodenal bulb,and biopsy revealed the presence of glandular *** ultrasonography(EUS)demonstr-ated relatively high echogenicity with a cystic *** muscularis propria was slightly elevated at the base of the *** was performed without *** formalin-fixed lesion size was 6 cm×3.5 cm×3 cm,showing nodular proliferation of non-dysplastic Brunner's glands compartmentalized by fibrous septa,confirming the diagnosis of *** of EMR or hot snare polypectomy are rare for duodenal BGH>6 *** this case,the choice of EMR was made by obtaining information on the base of the lesion as well as on the internal characteristics through *** Large duodenal lesions with good endoscopic maneuverability and no evident muscular layer involvement on EUS may be resectable via EMR.

关键词： Duodenum Brunner’s gland hyperplasia Brunner’s gland hamartoma Brunner’s gland adenoma Endoscopic mucosal resection Case report

Utility of plasma D-dimer for diagnosis of venous thromboembolism after hepatectomy

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World Journal of Clinical Cases 2024年第2期12卷 276-284页

作者： Taiichiro Miyake Hiroaki Yanagimoto Daisuke Tsugawa Masayuki Akita Riki Asakura Keisuke Arai Toshihiko Yoshida shinichi So Jun Ishida Takeshi Urade Yoshihide Nanno Kenji Fukushima Hidetoshi Gon Shohei Komatsu Sadaki Asari Hirochika Toyama Masahiro Kido Tetsuo Ajiki Takumi Fukumoto Division of Hepato-Biliary-Pancreatic Surgery Department of SurgeryKobe University Graduate School of MedicineKobe 650-0017HyogoJapan

BACKGROUND Venous thromboembolism(VTE)is a potentially fatal complication of *** use of postoperative prophylactic anticoagulation in patients who have undergone hepatectomy is controversial because of the risk of postoperative ***,we hypothesized that monitoring plasma D-dimer could be useful in the early diagnosis of VTE after *** To evaluate the utility of monitoring plasma D-dimer levels in the early diagnosis of VTE after *** The medical records of patients who underwent hepatectomy at our institution between January 2017 and December 2020 were retrospectively *** were divided into two groups according to whether or not they developed VTE after hepatectomy,as diagnosed by contrast-enhanced computed tomography and/or ultrasonography of the lower *** factors,including demographic data and perioperative D-dimer values,were compared between the two *** operating characteristic curve analysis was performed to determine the D-dimer cutoff *** and multivariate analyses were performed using logistic regression analysis to identify significant *** In total,234 patients who underwent hepatectomy were,of whom(5.6%)were diagnosed with VTE following hepatectomy.A comparison between the two groups showed significant differences in operative time(529 vs 403 min,P=0.0274)and blood loss(530 vs 138 mL,P=0.0067).The D-dimer levels on postoperative days(POD)1,3,5,7 were significantly higher in the VTE group than in the non-VTE *** the multivariate analysis,intraoperative blood loss of>275 mL[odds ratio(OR)=5.32,95%confidence interval(CI):1.05-27.0,P=0.044]and plasma D-dimer levels on POD 5≥21μg/mL(OR=10.1,95%CI:2.04-50.1,P=0.0046)were independent risk factors for VTE after *** Monitoring of plasma D-dimer levels after hepatectomy is useful for early diagnosis of VTE and may avoid routine prophylactic anticoagulation in the

关键词： Hepatectomy Malignant tumor Postoperative complication D-dimer Early diagnosis Venous thromboembolism

Tree diversity effects on forest productivity increase through time because of spatial partitioning

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Forest Ecosystems 2020年第3期7卷 327-333页

作者： shinichi Tatsumi Department of Biological Sciences University of Toronto ScarboroughTorontoONCanada Hokkaido Research Center Forestry and Forest Products Research InstituteHokkaidoJapan

Background: Experimental manipulations of tree diversity have often found overyielding in mixed-species plantations. While most experiments are still in the early stages of stand development, the impacts of tree diversity are expected to accumulate over time. Here, I present findings from a 31-year-old tree diversity experiment(as of2018) in ***: I find that the net diversity effect on stand biomass increased linearly through time. The species mixture achieved 64% greater biomass than the average monoculture biomass 31 years after planting. The complementarity effect was positive and increased exponentially with time. The selection effect was negative and decreased exponentially with time. In the early stages(≤ 3 years), the positive complementarity effect was explained by enhanced growths of early-and mid-successional species in the mixture. Later on(≥ 15 years), it was explained by their increased survival rates owing to vertical spatial partitioning — i.e. alleviation of self-thinning via canopy stratification. The negative selection effect resulted from suppressed growths of late-successional species in the bottom ***: The experiment provides pioneering evidence that the positive impacts of diversity-driven spatial partitioning on forest biomass can accumulate over multiple decades. The results indicate that forest biomass production and carbon sequestration can be enhanced by multispecies afforestation strategies.

关键词： Biomass productivity Complementarity effect Biodiversity and ecosystem functioning Forest dynamics Mixed plantation Plant succession Selection effect Shade tolerance Stand structure Tree diversity experiment

Experimental study on the free surface deformation in the oxide melt

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Science China(Technological Sciences) 2005年第5期48卷 481-488页

作者： YODA shinichi Space Utilization Research Center Office of Space Utilization System JAXA 2-2-1 Sengen Tsukuba Ibaraki 305 Japan

Experiments on the thermocapillary convection of high temperature Bi12SiO20 melts have been carried out in the in situ observation system. The steady flow pattern comprises of the main trunk and branches, which is deemed as the surface deformation. The oscillatory thermocapillary convection is characterized by the oscillatory main trunk and traveling branches. The transition of the melt from steady spatial to oscillatory behavior under the temperature differences 120, 60 and 10 K has been considered. The free surface deformation is observed to transform with the change of the applied temperature difference, which manifests that the thermocapillary convection is sensitive to the temperature difference. Moreover, taking the temperature distribution into account, it is noted that the deformation is formed in the colder area of the melt. The oscillatory frequency of the main trunk, which is also sensitive to the applied temperature difference, increases with the rise of temperature.

关键词： deformation of free surface, in situ observation, thermocapillary convection.

ESTIMATION OF CHAIN REACTION BANKRUPTCY STRUCTURE BY CHANCE DISCOVERY METHO—WITH TIME ORDER METHOD AND DIRECTED KEYGRAPH

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Journal of Systems Science and Systems Engineering 2007年第4期16卷 489-498页

作者： shinichi GODA Yukio OHSAWA School of Engineering The University of Tokyo113-8656 Japan

Chain reaction bankruptcy is regarded as common phenomenon and its effect is to be taken into account when credit risk portfolio is analyzed. But consideration and modeling of its effect leave much room for improvement. That is mainly because method for grasping relations among companies with limited data is underdeveloped. In this article, chance discovery method is applied to estimate industrial relations that are to include companies＇ relations that transmit chain reaction of bankruptcy. Time order method and directed KeyGraph are newly introduced to distinguish and express the time order among defaults that is essential information for the analysis of chain reaction bankruptcy. The steps for the data analysis are introduced and result of example analysis with default data in Kyushu, Japan, 2005 is presented. The structure estimated by the new method is compared with the structure of actual account receivable holders of bankrupted companies for evaluation.

关键词： Chance discovery credit risk chain reaction bankruptcy

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磨料浆体射流辅助TBM刀盘截割性能分析

机械工程学报 2024年第15期60卷 379-392页

作者：刘送永周方跃割泽伸一郭楚文李洪盛中国矿业大学机电工程学院徐州221116 中国矿业大学江苏省矿山智能采掘装备协同创新中心徐州221008 东京大学新领域创成科学研究科日本千叶277-8589 中国矿业大学低碳能源与动力工程学院徐州221116

针对高地应力环境以及高硬度、强磨蚀性等复杂岩层条件下隧道施工所面临的滚刀频繁失效问题,利用高压水射流辅助机械刀具破岩技术的降载减磨特性将切割能力相比纯水射流更强的磨料浆体射流引入TBM刀盘,并基于预切缝联合滚刀破岩载荷特... 详细信息

针对高地应力环境以及高硬度、强磨蚀性等复杂岩层条件下隧道施工所面临的滚刀频繁失效问题,利用高压水射流辅助机械刀具破岩技术的降载减磨特性将切割能力相比纯水射流更强的磨料浆体射流引入TBM刀盘,并基于预切缝联合滚刀破岩载荷特性对射流喷嘴于刀盘上的布置方案进行合理设计,在此基础上结合已有试验条件开展水射流-刀盘对混凝土岩样的室内截割试验,探究岩样抗压强度、射流压力、刀盘转速与推进速度对刀盘截割性能的影响规律以及各因素间的相关关系。研究结果表明:岩样抗压强度、刀盘转速与推进速度的增加均会推升刀盘扭矩与推进阻力水平,磨料浆体射流的存在有助于改善刀盘的载荷状态并削弱相关因素的影响水平,且射流压力愈高效果愈显著,但由于高压水射流切割破碎岩石比能相对于机械刀具更高,磨料浆体射流的引入在提升刀盘掘进速度的同时亦拖累了施工的经济性。各因素对刀盘扭矩的影响主次顺序依次为岩样抗压强度、刀盘转速、推进速度、射流压力,而对刀盘推进阻力的影响主次顺序则依次为岩样抗压强度、推进速度、射流压力、刀盘转速。

关键词：磨料浆体射流 TBM刀盘扭矩推进阻力比能

Pro-and anti-epileptic roles of microglia

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Neural Regeneration Research 2021年第7期16卷 1369-1371页

作者： shinichi Kinoshita Ryuta Koyama Laboratory of Chemical Pharmacology Graduate School of Pharmaceutical SciencesThe University of TokyoTokyoJapan

Microglia are brain-resident immune cells that contribute to the maintenance of brain *** the epileptic brain, microglia show various activation phenotypes depending on the stage of ***, it remains unclear whether microglial activation acts in a pro-epileptic or anti-epileptic *** mesial temporal lobe epilepsy, one of the most common form of epilepsies, microglia exhibit at least two distinct morphologies, amoeboid shape and ramified *** microglia are often found in sclerotic area, whereas ramified microglia are mainly found in non-sclerotic area;however, it remains unclear whether these structurally distinct microglia share separate roles in the epileptic ***, we review the roles of the two distinct microglial phenotypes, focusing on their pro-and anti-epileptic roles in terms of inflammatory response, regulation of neurogenesis and microglia-neuron interaction.

关键词： epilepsy epileptogenesis inflammatory cytokines microglia neurogenesis neuron-microglia interaction seizure

Analytical study of performance evaluation for seismic retrofitting of reinforced concrete building using 3D dynamic nonlinear finite element analysis

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Earthquake Engineering and Engineering Vibration 2011年第2期10卷 291-302页

作者： Yuichi Sato shinichi Kajihara Yoshio Kaneko Department of Architecture and Architectural Engineering Kyoto University Technology Center Taisei Corporation

This paper presents three-dimensional finite element （FE） analyses of an all-frame model of a three-story reinforced concrete （RC） building damaged in the 1999 Taiwan Chi-Chi Earthquake. Non-structural brick walls of the building acted as a seismic resistant element although their contributions were neglected in the design. Hence, the entire structure of a typical frame was modeled and static and dynamic nonlinear analyses were conducted to evaluate the contributions of the brick walls. However, the results of the analyses were considerably overestimated due to coarse mesh discretizations, which were unavoidable due to limited computer resources. This study corrects the overestimations by modifying （1） the tensile strengths and （2） shear stiffness reduction factors of concrete and brick. The results indicate that brick walls improve frame strength although shear failures are caused in columns shortened by spandrel walls. Then, the effectiveness of three types of seismic retrofits is evaluated. The maximum drift of the first floor is reduced by 89.3%, 94.8%, and 27.5% by Steel-confined, FuI1-RC, and Full-brick models, respectively. Finally, feasibility analyses of models with soils were conducted. The analyses indicated that the soils elongate the natural period of building models although no significant differences were observed.

关键词： reinforced concrete 1999 Taiwan Chi-Chi earthquake nonlinear finite element analysis seismic retrofit brick wall