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Polyarteritis nodosa diagnosed by surgically resected jejunal necrosis following acute abdomen

World Journal of Gastroenterology 2013年第18期19卷 2830-2834页

作者： Yuta Hiraike Makoto Kodaira Munetaka Sano Yasuyuki Terazawa shingo yamagata Syuzo Terada Masaharu Ohura Ken Kuriki Department of Gastroenterology Yaizu City Hospital Yaizu City Shizuoka 425-8505 Japan Department of Nephrology Yaizu City Hospital Yaizu City Shizuoka 425-8505 Japan Department of Pathology Yaizu City Hospital Yaizu City Shizuoka 425-8505 Japan

The differential diagnosis of acute abdomen is typically extremely broad in range, with vasculitis posing a rare but potentially life-threatening cause of acute abdomen. Here, we report a case of acute abdomen with bowel wall thickening limited to jejunum, accompanied by unexplained renal dysfunction. Later, the patient was diagnosed as having polyarteritis nodosa based on surgically resected jejunal necrosis. Despite aggressive treatment, including the use of steroid pulse therapy and continuous hemodiafiltration, the patient died. Although polyarteritis nodosa is extremely rare in patients with acute abdomen, acute abdomen is relatively common manifestation of that. And it is reported that involvement of small intestine suggests poorer prognosis. Our case highlights the importance of vasculitis as a differential diagnosis of patients with atypical acute abdomen. In this report, we not only review possible clues that might have led to an earlier diagnosis in this case, but also attempt to draw some lessons for treating similar cases in the future.

关键词： Acute abdomen Polyarteritis nodosa Jejunal necrosis

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Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues

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Asian Journal of Andrology 2003年第3期5卷 231-242页

作者： Junichi Fujii Yoshihito Iuchi shingo Matsuki Tatsuya Ishii Department of Biochemistry Yamagata University School of Medicine Yamagata 990 9585 JapanDepartment of Biochemistry Yamagata University School of Medicine Yamagata 990 9585 JapanDepartment of Biochemistry Yamagata University School of Medicine Yamagata 990 9585 JapanDepartment of Biochemistry Yamagata University School of Medicine Yamagata 990 9585 Japan

Reactive oxygen species (ROS) are produced under oxidative stress, such as high oxygen concentration and during the metabolic consumption of oxygen molecules. Male reproductive tissues appear to be continuously exposed to ROS produced by active metabolism. In addition, spermatozoa must pass through a high oxygen environment during the mating process. Thus, to maintain viable reproductive ability, a protective mechanism against oxidative stress is of importance. Here, we overview our current understanding of the cooperative function of antioxidative and redox systems that are involved in male fertility. Superoxide dismutase and glutathione peroxidase are major enzymes that scavenge harmful ROS in male reproductive organs. In turn, glutathione and thioredoxin systems constitute the main redox systems that repair oxidized and damaged molecules and also play a role in regulating a variety of cellular functions. While glutathione functions as an antioxidant by donating electrons to glutathione peroxidase and thioredoxin donates electrons to peroxiredoxin as a counterpart of glutathione peroxidase. In addition, aldo-keto reductases, which detoxify carbonyl compounds produced by oxidative stress, are present at high levels in the epithelia of the genital tract and Sertoli cells of the testis. Since these systems are involved in cross-talk, a comprehensive understanding will be required to maintain the physiological functions of male reproductive system.

关键词： reactive oxygen species superoxide dismutase glutathione thioredoxin peroxiredoxin aldo-keto reduc-tase

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Palestinian Migration Under the Occupation： Influence of Israeli Democracy and Stratified Citizenship

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Sociology Study 2013年第4期3卷 247-260页

作者： Aiko Nishikida shingo Hamanaka Tokyo University of Foreign Studies Japan yamagata University Japan

Continuous conflict has affected the migration of the Palestinians. Following the first exodus in 1948, they continued to migrate out of compulsion or for practical reasons. This paper clarifies the contemporary situation and perceptions of migration among the Palestinians in the West Bank, Gaza Strip, and East Jerusalem. Given the influence of regulations, this study situates those areas as part of the Israeli democratic system. Based on an original poll survey conducted in the summer of 2011, the analysis attempts to explain the relationship between migration and citizenship. People＇s migration is analyzed in relation to their different statuses as citizens. The variants of the statuses are considered to be a result of the system of stratified citizenship, and it is characterized as a component of the democratic system of Israel.

关键词： Palestine Israel stratified citizenship migration democracy

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