检索结果-南通市图书馆

Machine Intelligence Research 2023年第3期20卷 318-334页

作者： Wai-chung Kwan Hong-Ru Wang Hui-Min Wang Kam-Fai wong The Systems Engineering and Engineering Management Department The Chinese University of Hong KongHong Kong 999077China

Dialogue policy learning(DPL)is a key component in a task-oriented dialogue(TOD)*** goal is to decide the next action of the dialogue system,given the dialogue state at each turn based on a learned dialogue *** learning(RL)is widely used to optimize this dialogue *** the learning process,the user is regarded as the environment and the system as the *** this paper,we present an overview of the recent advances and challenges in dialogue policy from the perspective of *** specifically,we identify the problems and summarize corresponding solutions for RL-based dialogue policy *** addition,we provide a comprehensive survey of applying RL to DPL by categorizing recent methods into five basic elements in *** believe this survey can shed light on future research in DPL.

关键词： Dialogue policy learning(DPL) task-oriented dialogue system(TOD) reinforcement learning(RL) dialogue system Markov decision process

Curriculum Adaptation in Special Schools for Students with Intellectual Disabilities(SID):A Case Study of Project Learning in One SID School in Hong Kong

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Education in China 2014年第2期9卷 250-273页

作者： ZHANG Jia-Wei wong Lam CHAN Tak-Hang CHIU Chi-shing Hong Kong Institute of Educational Research The Chinese University of Hong KongHong KongChina

Using a qualitative case study approach,the authors analyzed the curriculum adaptation process for one project learning activity in School K,which is a SID school in the context of school-university *** sources of data were collected for triangulation,including interviews,documents and *** adaptation strategies in this study were analyzed from five perspectives:instructional goals,instructional content,instructional strategies,instructional settings,and student behavioral *** was found that curriculum adaptation efforts could help students with ID develop potential at their own level through project learning activates and teachers could also gain professional development during the university-school collaboration *** for future studies,enlarging the sample size,involving teachers’past orientations and motivations in the project learning process,and collecting quantitative data could all be taken into account.

关键词： special education students with intellectual disabilities(SID) curriculum adaptation project learning

A TV-Based Iterative Regularization Method for the Solutions of Thermal Convection Problems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Computational Physics 2013年第9期14卷 1120-1146页

作者： Eric T.chung Jeff C.-F.wong Department of Mathematics Lady Shaw BuildingThe Chinese University of Hong KongShatinHong Kong

Linear/nonlinear and Stokes based-stabilizations for the filter equations for damping out primitive variable(PV)solutions corrupted by uniformly distributed randomnoises are numerically studied through the natural convection(NC)aswell as the mixed convection(MC)*** most recognizable filter-scheme is based on a combination of the negative Laplace equation multiplied with the selection of the spatial scale and a linear function in order to preserve the uniqueness of the filtered solution.A more complicated filter-scheme,based on a Stokes problem which couples a filtered velocity and a filtered(artificial)pressure(or Lagrange multiplier)in order to enforce the incompressibility constraint,is also *** and Stokes basedfilters via nested iterative(NI)filters and the consistent splitting scheme(CSS)are proposed for the NC/MC *** by the total-variation(TV)model of image diffusion,well preserved feature flow patterns from the corrupted NC/MC environment are obtained by TV-Stokes based-filters together with the *** experimental results show that our proposed algorithms are effective and efficient in eliminating the unwanted spurious oscillations and preserving the accuracy of thermal convective fluid flows.

关键词： Linear/nonlinear differential filter Stokes differential filters Leray-alpha model total-variation regularization

Dipyridyl Azo Compound 4,4'-Azopyridine as a Potential Coating Material for Toilet Sanitizer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2023年第6期39卷 864-869页

作者： WANG Qiwei JIANG Lu LAM Pik-Ling CHUI chung-Hin wong Wai-Yeung Antibiotics Research and Reevaluation Key Laboratory of Sichuan Province Sichuan Industrial Institute of AntibioticsChengdu UniversityChengdu 610052P.R.China Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHung HomHong KongP.R.China Research and Development Division One Health International LimitedHong KongP.R.China

Good toilet hygiene can reduce the risk of pathogenic *** flushing,pathogenic bacteria can be spread by the water droplets,especially in the toilet *** coli(***)is one of the frequently occurring Gram-negative bacterial pathogens found in the toilet *** this study,we investigated the potential *** activity of some azobenzene *** them,compound 2,with the heterocyclic nitrogen in both phenyl rings,showed the strongest antibacterial effect on ***,with the minimum inhibitory concentration of 80μg/mL and the minimum bactericidal concentration of 320μg/*** 2 displayed a comparative zone of clearance[(14.50±2.29)mm]to that of ampicillin[(13.17±1.76)mm].The reactive oxygen species(ROS)assay suggested that compound 2 might induce the loss of bacteria via the oxidative stress by eliciting the generation of intracellular *** further examined the potential cytotoxicity of compound 2 to the human skin HaCaT *** 2-treated skin cells showed a good maintenance of cellular morphology and a clear definition of cell nuclei,with a satisfactory cell viability(ca.90%)at 80μg/***,compound 2 would be a possible antibacterial coating agent for the surface sanitizer of the toilet seats to inhibit the growth of ***.

关键词： Antibacterial Azobenzene Escherichia coli Skin cytotoxicity Toilet seat

Dietary analysis of the House Swift(Apus nipalensis)in Hong Kong using prey DNA in faecal samples

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Avian Research 2021年第1期12卷 86-101页

作者： Chun Ting chung Hok Sze wong Man Long Kwok Qi Meng King Ming Chan School of Life Sciences The Chinese University of Hong KongSha Tin 999077N.TChina Swift and Swallow Research Group The Hong Kong Bird Watching Society7CV Ga Building532 Castle Peak RoadLai Chi KokKowloonHong Kong 999077China

Background:To understand the dietary composition of the highly aerial swift(Apodidae),ecologists conventionally depend on the morphological identification of prey items from food boluses or stomach contents,but these techniques are often invasive,require expertise in identification,and often cannot produce accurate identifications at the species ***:DNA barcoding was used to analyse the dietary composition of House Swifts(Apus nipalensis)in Hong Kong,*** samples from five different colonial nest sites were collected between 2019 and *** used universal primers to amplify a region of the cytochrome C oxidase gene from prey DNA in the faecal samples for identification ***:Ten different orders and 44 families from three different classes of Arthropoda were identified in the collected faecal ***,Hemiptera and Diptera were the most prevalent groups of prey found in the *** in the dietary composition of House Swifts during the breeding(April to September)and nonbreeding(October to March)season were also ***,particularly ants(Formicidae),were predominant in the diet during the breeding season,whereas Diptera and Hemiptera were predominant during the non-breeding ***:The prey groups identified in this study were similar to those identified in a previous study of the diet of House Swift,which also suggests a possible role of House Swifts in reducing the numbers of local insect *** study demonstrates the usefulness of applying molecular tools for the dietary analysis of aerial *** local forested areas may be crucial for the maintenance of House Swift population.

关键词： Diet DNA barcoding House swift Urbanisation threat

Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2023年第6期10卷 2260-2262页

作者： Guodong Li Qi Huang Vincent Kam Wai wong Wanhe Wang chung-Hang Leung Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine University of MacaoMacao SAR 999078China Dr.Neher's Biophysics Laboratory for Innovative Drug Discovery State Key Laboratory of Quality Research in Chinese MedicineMacao University of Science and TechnologyMacao SAR 999078China Institute of Medical Research Northwestern Polytechnical UniversityXi'anShaanxi 710072China Macao Centre for Research and Development in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao SAR 999078China Department of Biomedical Sciences Faculty of Health SciencesUniversity of MacaoMacao SAR 999078China Zhuhai UM Science and Technology Research Institute ZhuhaiGuangdong 519000China

Histone methyltransferase enzyme SET7 and mixed-lineage leukemia protein(MLL)complex are crucial co-activators of androgen receptor(AR)and have recently emerged as potential therapeutic targets for advanced castration-resistant prostate cancer(CRPC).In this study,we described the identification of a rhodium-based hybrid complex(SM_1)as a potent blocker of AR activity via simultaneously inhibiting SET7 and MLL complex activity,which makes it a potential lead scaffold for CPRC drug development.

关键词： cancer inhibiting treatment

Neoadjuvant treatment for resectable pancreatic adenocarcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2016年第1期7卷 1-8页

作者： John wong Naveenraj L Solomon chung-Tsen Hsueh Division of Medical Oncology and Hematology Department of Internal Medicine Loma Linda University Department of Surgery Loma Linda University

Pancreatic adenocarcinoma is the fourth leading cause of cancer mortality in the United States in both men and women, with a 5-year survival rate of less than 5%. Surgical resection remains the only curative treatment, but most patients develop systemic recurrence within 2 years of surgery. Adjuvant treatment with chemotherapy or chemoradiotherapy has been shown to improve overall survival, but the delivery of treatment remains problematic with up to 50% of patients not receiving postoperative treatment. Neoadjuvant therapy can provide benefits of eradication of micrometastasis and improved delivery of intended treatment. We have reviewed the findings from completed neoadjuvant clinical trials, and discussed the ongoing studies. Combinational cytotoxic chemotherapy such as fluorouracil, leucovorin, irinotecan, and oxaliplatin and gemcitabine plus nanoparticle albumin-bound(nab)-paclitaxel, active in the metastatic setting, are being studied in the neoadjuvant setting. In addition, novel targeted agents such as inhibitor of immune checkpoint are incorporated with cytotoxic chemotherapy in early-phase clinical trial. Furthermore we have explored the utility of biomarkers which can personalize treatment and select patients for target-driven therapy to improve treatment outcome. The treatment of resectable pancreatic adenocarcinoma requires multidisciplinary approach and novel strategies including innovative trials to make progress.

关键词： Pancreatic cancer Resectable pancreatic adenocarcinoma Neoadjuvant treatment Biomarkers Chemotherapy Surgery

Cultivation of microalgae for biodiesel production:A review on upstream and downstream processing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2018年第1期26卷 17-30页

作者： Xin Bei Tan Man Kee Lam Yoshimitsu Uemura Jun Wei Lim chung Yiin wong Keat Teong Lee Chemical Engineering Department Universiti Teknologi PETRONAS Centre for Biofuel and Biochemical Research Universiti Teknologi PETRONAS Fundamental and Applied Science Department Universiti Teknologi PETRONAS School of Chemical Engineering Universiti Sains MalaysiaEngineering Campus

Fluctuating market price of fossil fuel and overwhelming emission of greenhouse gases to the atmosphere have resulted in climate change and have been a global concern in this decade. Hence, biodiesel has become an alternative option to fossil diesel as it is renewable and environmentally friendly. Nevertheless, this alternative fuel that is usually derived from terrestrial oil crops will cause shortage in food supply and deforestation if mass production is realized. In recent years, cultivation of aquatic microorganism(particularly microalgae) to produce biodiesel is considered as a practical solution due to their high growth rate and ability to synthesize large quantity of lipid within their cell. However, the development of energy and cost-efficiency of microalgae cultivation system are the main issues in producing renewable microalgae biodiesel. Of late, wastewater or organic compost has been used as the cultivation medium as it can provide sufficient nutrients to sustain microalgae *** cultivation method and system are vitally important as these factors undoubtedly affect the final microalgae biomass and lipid yield. In this review, the cultivation system of microalgae, nutrients demanded for microalgae production, cell harvesting and drying, microalgae oil extraction, and utilization of microalgae biomass for biodiesel production are introduced and discussed. It is anticipated to convey clearer perspectives in upstream and downstream processes in microalgae-derived biodiesel production.

关键词： Microalgae Cultivation Lipid Biodiesel Harvesting

Methodology for estimation of river discharge and application of the Zhujiang River Estuary (ZRE)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2004年第3期23卷 377-386页

作者： CHENJay-chung wongLai-Ah CenterforCoastalandAtmosphericResearch HongKongUniversityofScienceandTechnologyHongKongChina

The ZRE is a very complicated estuary with multi-river inlets. The total sum of river discharge in the upstream (away from the tidal influence region) of the Zhujiang River can be easily measured. However, when the total river discharges into the estuary from eight inlets, it is a very difficult task to obtain a continuous river discharge flux data from each branch of the Zhujiang River. However, the different ratios of river discharges between the river branches can significantly affect the estuarine circulation feature and baroclinic process. Moreover, the accuracy of numerical forecast for the estuarine circulation is very much dependent on the accuracy of the time history of the river discharge flux for each branch. Therefore, it is important to estimate river discharge from each branch in order to improve the accuracy of the model forecast for the circulation of the ZRE. The development of a new estimation method of the river discharges is focused on based on the system identification theory, numerical modeling and the time history data from the CODAR observed sea surface current. The new approach has been applied to estimating the time history (hourly) of river discharge from each branch in the upstream of the ZRE.

关键词： River Discharge Estimation CODAR Estuary

Distributed Resilient Platoon Control of Vehicular Cyber Physical Systems Subject to DoS Attacks

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Distributed Resilient Platoon Control of Vehicular Cyber Phy...