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Structure Modification of Alloy Solidified With Electromagnetic Field

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Journal of Iron and Steel Research International 2012年第S1期19卷 203-207页

作者： IWAI Kazuhiko kohama Takenori NISHIMURA Tomohiro EcoTopia Science Institute Energy Science Research DepartmentNagoya UniversityFuro-choChikusa-kuNagoya 464-8603Japan Department of Materials Physics and Energy EngineeringNagoya UniversityFuro-choChikusa-kuNagoya464-8603Japan

A S45C carbon steel has been solidified trader different electromagnetic conditions to investigate the effect of the electromagnetic force imposition and its imposing period on the solidified structure in this *** excitation of the electromagnetic force,a static magnetic field and a direct electric current were simultaneously imposed on a sample under a certain period of the *** the solidification,the microstructures were observed and compared each other. As the results,microstructure of the S45C steel under the simultaneous imposition of a static magnetic field of 1T and a direct electric current of 20A in the latter stage of its solidification was dendritic while it was globular if the electromagnetic force was imposed during the whole solidification period.

关键词： electromagnetic force carbon steel solidification

Kinase and non-kinase activities of myosin lightchain kinase of smooth muscle

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Kinase and non-kinase activities of myosin lightchain kinase...

第三届中日双边药理学和临床药理学学术会议

作者： kohama Kazuhiro Department of Molecular ＆ Cellular Pharmacology Gunma University Graduate School of MedicineGunma 371-8511Japan

＜正＞AIM Myosin light-chain kinase （MLCK） regulates smooth muscle contraction by phosphorylating 20- kDa myosin light chain （MLC20） of smooth muscle myo- sin to activate the actin-myosin （A-M） ***- though this mode of action is well-established,there are numerous reports of the contraction that is not associated with MLC20 *** domain structure of MLCK is composed of the central kinase activity,the N- terminal actin-binding activity,and C-terminal myosin- binding activity.I will overview that the actin-and myo- sin-binding domains may regulate the A-M interaction. METHODS The eDNA from bovine stomach was expressed in *** and then purified by the affinity *** actin-binding and myosin-binding fragments from the both terminals were also expressed and *** MLCK devoiding the kinase activity was produced by mutating the ATP-binding sequence of the kinase *** MLCK exerted stimulatory and inhibitory effects on the A-M interaction with the un- phosphorylated and phosphorylated myosins of smooth mus- cle,*** effects were also evident with the mutant MLCK devoiding the kinase activity,indicating that the effect was not attributable to phosphorylate MLC20.I confirmed the stimulatory and inhibitory effects with the myosin-and actin-binding fragments,respective- *** MLCK exerts regulatory activity through its myosin-and actin-binding activities.

关键词： myosin light-chain kinase actin-and myosin-binding domains regulation of contraction

Characterization of macrophage mutants established by their resistance to LPS and cycloheximide-induced apopotic cell death

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Advances in Bioscience and Biotechnology 2012年第6期3卷 770-781页

作者： Fumio Amano Shoko Tsukabe Reiko Teshima Keiko Waku Kiyoko kohama Laboratory of Biodefense & Regulation Osaka University of Pharmaceutical Sciences Osaka Japan

Macrophages are activated by bacterial lipopolysaccharide (LPS) to produce inflammatory cytokines such as TNF-α or reactive oxygen species such as nitric oxide or superoxide anion. However, in the presence of an inhibitor of protein synthesis, cyclohex-imide (CHX), at 10 μg/mL, LPS at 100 ng/mL induced macrophage apoptosis rapidly without producing phenotypes of activated macrophages. In order to understand the mechanism underlying LPS-induced cytotoxicity toward macrophages, we isolated mutant cells from a macrophage-like cell line, J774.1, as clones resistant against the cytotoxic effects of LPS + CHX by using a somatic cell genetics protocol. All of the mutant clones, designated as LCR mutants, showed resistance to the cell death induced by LPS + CHX as well as to that induced by higher doses of LPS alone, as did the LPS1916 mutant cell line, which had been previously established by its resistance to 100 μg/mL LPS. Characterization of the activated macrophage phenotypes revealed that these mutants showed reduced production of TNF-α and nitric oxide in response to LPS. Further analysis showed a much reduced amount of [125I]LPS-binding and lower CD14 expression on the cell surface, in spite of an adequate intracellular expression of CD14 molecules. Besides, the molecular weight of CD14 on these mutants was around 40-48 kDa, smaller than that of the wild-type JA-4 cells (around 50-55 kDa), suggesting impaired CD14 maturation in these mutants. However, expression of Toll-like receptor 4 (TLR4) and Myd 88 on the cell surface was not different between the wild type and the mutant cells. These results suggest that LCR mutants have common phenotypes of mal-expression of CD14 molecules on the macrophage cell surface, leading to not only reduced responses to LPS-mediated macrophage activation but acquisition of resistance to LPS-induced apoptotic cell death in the presence of CHX.

关键词： Macrophage J774.1 Cell Line LPS Apoptosis CD14

The structure and function of major Ca2+ binding protein (CBP40) in slime mold, Physarum pofycephalum.

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The structure and function of major Ca2+ binding protein (CB...

Third Congress of the Asian-Pacific Organization for Cell Biology

作者： Akio Nakamura Tsuyoshi Okagaki Takashi Takagi Kazuhiro kohama Dept. of pharmacol. Gunma Univ. Sch. of Med. Maebashi 371 Biol. Inst.Fac. of Sci. Tohoku Univ.Sendai 980

We purified CBP40 as a major Ca2+ binding protein with Mr 40kDa from plasmodia of lower eukaryote, Physarum. Cloning of the protein revealed that it is consisted of 355 a.a. residues. The CBP40 had following

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Evapotranspiration and Removal Performance in the Treatment of High Salinity LandfilI-Leachate Using HSF

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Journal of Environmental Science and Engineering(B) 2016年第9期5卷 440-450页

作者： Tokuo Yano Kazuhiro Yamada Masatomo Nakayama Akiko Inoue-kohama shinya Sato Keijiro Enari Department of Environment and Energy Tohoku Institute of Technology Sendai 982-8577 Japan Department of Civil Engineering and Management Tohoku Institute of Technology Sendai 982-85 77 Japan Sendai Kankyo Kaihatsu Co. Ltd. Sendai 989-3212 Japan

In this study, the water budget in the treatment of high salinity landfill-leachate was estimated and the influence of evapotranspiration （ET） on treatment performance was investigated. The salinity of the inside of horizontal subsurface flow constructed wetland （HSF） of the raw leachate inflow was 15.0± 3.4 ***/L which was in the level of the salinity of the survival limit of reed, and that of the double diluted leachate inflow was 9.3 ± 1.9 ***7L. There were large differences in the vegetation between HSF of the raw leachate inflow and that of the double diluted leachate inflow. The dense vegetation bed of double diluted leachate inflow during the growing season （April-October） provided a high ET and a large water loss, which made great contributions to the reduction of the outflow load of COD and T-N. The HSF with die-back reeds in the non-growing season （November-March） provided a slight ET and a small water loss and made less of a contribution to pollutant removal compared to the HSF with dense vegetation bed during the growing season. However, the HSF with die-back reeds during the non-growing season exhibited higher removal performance than the unplanted HSF.

关键词： Evapotranspiration HSF high salinity landfill-leachate removal performance water budget.

Effect of Salinity on Reeds in the Treatment of High Salinity LandfilI-Leachates Using HFs

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Journal of Environmental Science and Engineering(B) 2014年第3期3卷 142-150页

作者： Tokuo Yano Mika Okanuma Yoshiki Kumagai Kazuaki Sato Akiko Inoue-kohama Keijiro Enari Department of Environmental Information Engineering Tohoku Institute of Technology Sendai 982-8577 Japan

The growth of reeds was impeded remarkably under a salinity of 15.0±3.4 g CI·L-1 in the first year of this experiment, recovered in the second year and then increased year-by-year afterward. The growth of reeds under a salinity of 9.3±1.9 g CI·Ll was much better than those under 15.0 ± 3.4 g CI·L1. The stress effect was significant for shoot extension but not for the quantity of shoots increase. The dense vegetation bed during the vegetation period （June-October） provided a high rate of evapotranspiration and water loss from HFs （horizontal subsurface flow constructed wetlands）, which made large contributions to reducing pollutant load. The HFs with die-back reeds in the non-vegetation periods （November-March） provided slight evapotranspiration and water loss and made less of a contribution to reducing pollutants removal compared to HFs with the dense vegetation bed in the vegetation periods. However, the HFs with die-back reeds in the non-vegetation periods had higher removal performance than the HF without reeds. This indicated that the rhizosphere of HFs with reeds might play important roles, such as that the microbes around rhizomes might have a higher amount of pollutant-removing microbe activity than those in the HF without reeds during the non-vegetation period.

关键词： Landfill-leachate high-salinity HFs reeds effect.

利用口述史料研究中国近现代史的可能性——以山西省盂县日军性暴力研究为例

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史林 2006年第3期 63-72页

作者：小浜正子葛涛日本大学文理学部上海社会科学院历史研究所

近年来,虽然遭遇阻力,但日本国内对于中日战争时期日军在华实施性暴力的调查、研究工作还是取得了重要进展。以石田米子为中心的调查小组经过长期不懈的努力,对当年日军在山西省盂县实施性暴力的事实进行了确证和揭露。本文在介绍石田... 详细信息

近年来,虽然遭遇阻力,但日本国内对于中日战争时期日军在华实施性暴力的调查、研究工作还是取得了重要进展。以石田米子为中心的调查小组经过长期不懈的努力,对当年日军在山西省盂县实施性暴力的事实进行了确证和揭露。本文在介绍石田小组的工作及其意义的同时,还对战时日军的性暴力活动进行了分类,并结合史学理论探讨了利用口述史料研究中国近现代史的意义与可能性。

关键词：日军性暴力前线·底端型的日军性暴力口述史料与文献史料建构主义与实证史学

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电磁场作用对钢的组织结构控制

电磁场作用对钢的组织结构控制

作者： Kazuhiko Iwai Takenori kohama 日本名古屋大学Eco-topia科学研究所

在垂直方向的静态磁场和水平方向的直流电或者交流电的同时作用下进行了碳素钢凝固。电磁力作用于钢,从而会影响凝固过程的组织形态。切割和侵蚀在不同电磁力作用下凝固的试样,以观察宏观和微观的组织形貌。没有电磁力作用下形成的凝固... 详细信息

在垂直方向的静态磁场和水平方向的直流电或者交流电的同时作用下进行了碳素钢凝固。电磁力作用于钢,从而会影响凝固过程的组织形态。切割和侵蚀在不同电磁力作用下凝固的试样,以观察宏观和微观的组织形貌。没有电磁力作用下形成的凝固组织是枝晶晶粒结构。相反,在0.3T静态磁场和20A直流电的共同作用条件下形成球状晶结构。在0.3T静态磁场和80A、2kHz交流电的共同作用条件下凝固组织只是有一部分是球状晶结构。因此,从电流强度的角度来看,改善凝固组织由枝晶晶粒到球状晶粒结构的转变,静态电磁场和直流电的共同作用更好于静态电磁场和交流电的共同作用。

关键词：凝固微观组织磁场电流

APPLICATION OF THE STERILE INSECT TECHNIQUE AGAINST THE MELON FLY AND SWEET POTATO WEEVILS IN OKINAWA, JAPAN

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APPLICATION OF THE STERILE INSECT TECHNIQUE AGAINST THE MELO...

The ⅩⅤth International Plant Protection Congress

作者： T.kohama D.Haraguchi T.Uesato K.Urasaki S.Ohno Fruit Fly Eradication Project Office Okinawa Prefectural Government 123 Maji Naha Okinawa 902-0072 Japan Fruit Fly Eradication Project Office Okinawa Prefectural Government 123 Maji Naha Okinawa 902-0072 Japan Fruit Fly Eradication Project Office Okinawa Prefectural Government 123 Maji Naha Okinawa 902-0072 Japan Fruit Fly Eradication Project Office Okinawa Prefectural Government 123 Maji Naha Okinawa 902-0072 Japan Fruit Fly Eradication Project Office Okinawa Prefectural Government 123 Maji Naha Okinawa 902-0072 Japan