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Preliminary Study on the Effectiveness of Different Durations of Hot Towel Application to the Back during Bed Bathing

Asia Navigation Conference 2009

作者： Keiji SASAYA Masao FURUSHO Yoshiji yano Toyama National College of Maritime Technology Graduate School of Maritime Sciences Kobe University 1-2 EbieNeriyaImizu city Toyama Prefecture

＜正＞*** Whether it is labor at sea or on land,the protection of the life,body,and health of workers is more important than anything *** number of Japanese mariners or seafarers working at sea in Japan is 74,618（2007）,a number that is extremely small compared to the total working population of approximately 63,000,000 workers（2007）.The ratio of accidents involving mariners（occupational accidents causing absences of more than four days）,however,is consistently higher when compared with occupational accidents on land（See Fig.1 and Fig.2）.

关键词： Safety and Health Mariner’s accident Mariners Law

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Open Journal of Nursing 2017年第12期7卷 1375-1386页

作者： Inaho Shishido Yuka Yamaguchi Rie Miyata Sakiko Kutomi Rika yano KKR Medical Center Sapporo Japan The University of Tokyo Hospital Tokyo Japan Elderly Support Section Fukagawa City Fukagawa Japan Toranomon Hospital Tokyo Japan Faculty of Health Sciences Hokkaido University Sapporo Japan

The purpose of this study was to determine the most effective duration of hot towel application during bed bathing, based on temporal changes in skin surface temperature, towel temperature, and subjective comfort. As a secondary objective, differences in skin surface temperature and subjective comfort for hot towel application on the back and dry towel wiping alone were evaluated. For the first objective, hot towels were applied on the lower back of 20 healthy adults, for different duration (10, 15, and 20 s), with a 10-s duration found to be the most effective. For the second objective, we compared bed bathing with hot towel application to dry wiping alone, n 21 healthy adult participants. A 10-s hot towel application increased the surface temperature of the skin (+0.5℃) and provided a perceived sensation of warmth and comfort. In contrast, dry wiping significantly decreased the surface skin temperature (-0.8℃). In conclusion, hot towel application increased skin surface temperature and improved subjective warmth and comfort during bed bathing.

关键词： Bed Bath Hot Towel Application Skin Surface Temperature

Relationship between Sleep and Subjective Fatigue in Rotating Shift Nurses: Validation Using a Wearable Device

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Open Journal of Nursing 2018年第4期8卷 272-280页

作者： Yuko Yoshida Naomi Sumi Naotaka Sugimura Fumie Nemoto Rika yano Faculty of Health Sciences Hokkaido University Sapporo Japan Graduate School of Health Sciences Hokkaido University Sapporo Japan Tokeidai Memorial Hospital Sapporo Japan

The objective of this study was to determine if sleep indicators are associated with subjective fatigue in nurses working in a rotating, two-shift system with a 16-hour night shift, using the wearable device Fitbit One. Subjective fatigue was evaluated using the Subjective Fatigue Symptom Questionnaire (SFSQ), a rating scale developed by the Working Group for Occupational Fatigue of the Japan Society for Occupational Health. Subjects were asked to continuously wear a Fitbit One to obtain the following data: time in bed (TIB), deep sleep time, length and frequency of nighttime awakening, sleep efficiency, waking time, and bed time. Nurses had a mean age and standard deviation of 33.2 ± 7.5 years and had worked as nurses for 9.8 ± 6.2 years on average. Eight nurses were in their 20s (42.1%), 5 in their 30s (26.3%), and 6 in their 40s (31.6%). All participants were female. Participants’ SFSQ scores calculated from the 9 evenings in the study period were averaged to establish a threshold for categorizing high-fatigue (HF) and low-fatigue (LF) groups. No significant differences were found between HF and LF nurses in terms of TIB, deep sleep time, nighttime awakening time or frequency, or sleep efficiency on any type of day (as classified by shift, day off, etc.). Nurses in both groups woke up significantly later on days off and on pre-night-shift days than on day-shift days. These results demonstrate the variation in sleep patterns of nurses on a rotating, two-shift system between day-shift and night-shift days.

关键词： Fatigue Rotating Shifts Nurse Sleep

Relationship between Death Conference Experiences and Nurses’ Terminal Care

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Open Journal of Nursing 2020年第4期10卷 381-395页

作者： Yuko Harding Yoshiko Ishibashi Mikiko Mori Masako yano Michiyo Ando Faculty of Nursing St. Mary’s College Kurume Japan Department of Nursing St. Mary’s Hospital Kurume Japan

Background: The experiences of death conference (DC) are regarded as improving the quality of nurses’ terminal care and developing nursing minds. Few studies in Japan clarify quantitatively how nurses’ participation in DC is related to nurses’ terminal care. Aim: This study aims to clarify the relationship between DC experiences and nurses’ terminal care using the prepared Terminal Care Nursing Self-Assessment Sheet. Method: The study is approved by the Ethics Review Board of St. Mary’s College, and the hospital where the survey was conducted. This study was an observational and cross-sectional study using an anonymous, self-completed questionnaire composed of the newly created Terminal Care Nursing Self-Assessment Sheet. Its evaluation items consist of six categories (Reflection, Cooperation, Response to patients, Response to patients’ family, Specific measures for nursing, and Feelings of the nurse), and 14 questions. The questionnaires were conducted for 144 nurses in the ER, ICU, and Palliative Care Ward (Hospice Ward) in a general hospital in Japan. For analysis, JMP ver.14.2 was used to perform a Chi-square test, Wilcoxon/Mann Whitney test, univariate, and multivariate logistic regression analysis. Results: One hundred thirty-nine participants (97%) were included in the final analysis. Forty-three nurses had DC experiences, and 96 had no experience. The median number (IQR;interquartile range) of DC experiences was 5.5 (2 - 22.5). There were significant differences in five of the above categories;however, there was no significant association in the five questions of the nurse’s stress on response to patients and patients’ family and specific measures for nursing regarding postmortem treatment for patients between DC experiences and Nurses’ terminal care. Conclusion: DC that looks back on terminal care has significance as an opportunity to consider the way of terminal concerns and direction of future care. It is required to raise the quality of DC for focusing o

关键词： Death Conference DC Terminal Care Self-Assessment Nurses

Production, purification and characterization of D-aspartate oxidase from the fungus <i>Trichoderma harzianum</i>SKW-36

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Advances in Bioscience and Biotechnology 2012年第1期3卷 7-13页

作者： Shigekazu yano Hiroyuki Ozaki shinji Matsuo Masahiro Ito Mamoru Wakayama Department of Biotechnology Faculty of Life Sciences Ritsumeikan University Kusatsu Shiga Japan

Trichoderma harzianum Rifai SKW-36 produced two kinds of D-amino acid oxidizing enzymes. One enzyme was D-aspartate oxidase acting on acidic D-amino acids such as D-aspartate and D-glutamate and another one was D-amino acid oxidase acting on neutral D-amino acid such as D-phenylalanine and D-methionine. These enzymes in the cell-free extract were separated by DEAE-Toyopearl ion-exchange column chromatography. Casamino acids, peptone, and yeast extract as carbon and nitrogen sources were effective for the production of the enzymes. No D-amino acid tested induced the production of the enzymes. Casamino acid (0.33%) as carbon and nitrogen source gave a highest specific activity of D-aspartate oxidase among media tested. D-Aspartate oxidase, which was purified by four-step column chromatography in addition to ammonium sulfate precipitation, exhibited a subunit molecular mass of 40 kDa by SDS-PAGE analysis. D-Aspartate, D-glutamate and N-methyl-D- aspartate were oxidized as substrates with the specific activities of 7.80 U/mg, 4.90 U/mg, and 4.22 U/mg, respectively. D-Asparagine, D-glutamine, D-alanine, and D-valine were slightly oxidized. No other D- amino acids tested were inert. The enzyme exhibited relatively wide substrate specificity compared to D-aspartate oxidases reported so far. The pH and temperature optima were 7.5 - 8.0 and 35°C, respectively. The enzyme was stable at pH 6.0 - 9.0. About 75% of the enzyme activity was retained even after treating the enzyme at 50°C for 10 min. The enzyme activity was inhibited not by benzoate and tartrate, but 60% and 24% by fumarate and malonate, respectively.

关键词： D-Aspartate Oxidase Trichoderma harzianum Purification Characterization

THE DEGREE OF CRYSTALLINITY OF MULTICOMPONENT POLYMERS BY X-RAY DIFFRACTION ANALYSIS

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Chinese Chemical Letters 1991年第4期2卷 323-324页

作者： Zhi Shen MO Bao Quan yano Hong Tang ZHANO Changchun Institute of Applied Chemistry,Academia Sinica,Changchun 130022

Based on the X-ray scattering intensity theory,the correction factors of the degree of crystallinity formulae of the multicomponent polymers have been clearly *** formula of degree of erystallinity of the multicomponent polymers was derived in terms of the WAXD theory ahd improved graphic multipeak resolution *** results calculated are compatible with the density measurement.

关键词： PP Ho Li Zhang THE DEGREE OF CRYSTALLINITY OF MULTICOMPONENT POLYMERS BY X-RAY DIFFRACTION ANALYSIS Poly

Performance of redox flow battery systems in Japan

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储能科学与技术 2013年第3期2卷 233-236页

作者： Shibata Toshikazu Kumamoto Takahiro Nagaoko Yoshiyuki Kawase Kazunori yano Keiji Sumitomo Electric Industries Ltd.1-1-3 ShimayaKonohana-kuOska 554-0024Japan

Renewable energies, such as solar and wind power, are increasingly being introduced as alternative energy sources on a glosbal scale toward a low-carbon society. For the next generation power network, which uses a large number of these distributed power generation sources, energy storage technologies will be indispensable. Among these technologies, battery energy storage technology is considered to be most viable. Sumitomo Electric Industries, Ltd. has developed a redox flow battery system suitable for large scale energy storage, and carried out several demonstration projects on the stabilization of renewable energy output using the redox flow battery system. This paper describes the advantages of the redox flow battery and reviews the demonstration projects.

关键词： redox flow battery energy storage renewable energy smart grid wind turbine photovoltaics

Sodium-glucose co-transporter-2 inhibitor-associated euglycemic diabetic ketoacidosis that prompted the diagnosis of fulminant type-1 diabetes:A case report

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World Journal of Clinical Cases 2021年第13期9卷 3163-3169页

作者： Taro Yasuma Yuko Okano Soichiro Tanaka Kota Nishihama Kazuhito Eguchi Chisa Inoue Kanako Maki Akihiro Uchida Mei Uemura Toshinari Suzuki Corina N D'Alessandro-Gabazza Esteban C Gabazza Yutaka yano Department of Diabetes Metabolismand Endocrinology and ImmunologyMie UniversityTsu 514-8507Japan Department of Diabetes Metabolismand EndocrinologyMie UniversityTsu 514-8507Japan Department of Immunology Mie University School of MedicineMie UniversityTsu 514-8507Japan Department of Immunology Mie University Faculty and Graduate School of MedicineTsu 514-8507Japan Department of Diabetes Mie University Graduate School of MedicineTsu 514-8507Japan

Fulminant type 1 diabetes mellitus(FT1DM)is a subtype of type 1 diabetes mellitus characterized by an abrupt onset and a rapid and complete functional loss of isletβ*** is a very rare disease generally associated with ketoacidosis and the absence of circulating pancreatic islet-related *** ketoacidosis with normal blood glucose levels has been reported during sodiumglucose co-transporter 2(SGLT2)inhibitor *** SUMMARY The patient was a 43-year-old woman that consulted a medical practitioner for malaise,thirst,and *** analysis showed high blood glucose levels(428 mg/dL),a mild increase of hemoglobin A1c(6.6%),and increased ketone bodies in *** patient was diagnosed with type 2 diabetes *** patient was initially treated with insulin,which was subsequently changed to an oral SGLT2 *** to glutamic acid decarboxylase were *** days after receiving oral SGLT2 inhibitor,she consulted at Mie University Hospital,complaining of fatigue and *** analysis revealed diabetic ketoacidosis with almost normal blood glucose *** endogenous insulin secretion was markedly low,and the serum levels of islet-related autoantibodies were *** made the diagnosis of FT1DM with concurrent SGLT2 inhibitor-associated euglycemic diabetic *** patient's general condition improved after therapy with intravenous insulin and withdrawal of oral *** was discharged on day 14 with an indication of multiple daily insulin *** This patient is a rare case of FT1DM that developed SGLT2 inhibitor-associated diabetic ketoacidosis with almost normal blood glucose *** case report underscores the importance of considering the diagnosis of FT1DM in patients with negative circulating autoantibodies and a history of hyperglycemia that subsequently develop euglycemic diabetic ketoacidosis following treatment with a SGLT2 inhibitor.

关键词： Euglycemic diabetic ketoacidosis Sodium-glucose cotransporter 2 inhibitors Fulminant type 1 diabetes Case report

The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury

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Cellular & Molecular Immunology 2011年第4期8卷 305-314页

作者： Mitsuhiro Yamada Hiroshi Kubo Seiichi Kobayashi Kota Ishizawa Mei He Takaya Suzuki Naoya Fujino Hiroyuki Kunishima Masamitsu Hatta Katsushi Nishimaki Tetsuji Aoyagi Kouichi Tokuda Miho Kitagawa Hisakazu yano Hirokazu Tamamura Nobutaka Fujii Mitsuo Kaku Department of Regional Cooperation for Infectious Diseases Tohoku University Graduate School of MedicineSendaiMiyagiJapan Department of Advanced Preventive Medicine for Infectious Disease Tohoku University Graduate School of MedicineSendaiMiyagiJapan Department of Respiratory Medicine Japanese Red-Cross Ishinomaki HospitalIshinomakiMiyagiJapan Department of Infection Control and Laboratory Diagnostics Tohoku University Graduate School of MedicineSendaiMiyagiJapan Department of Clinical Microbiology with Epidemiological Research&Management and Analysis of Infectious Diseases Tohoku University Graduate School of MedicineSendaiMiyagiJapan Institute of Biomaterials and Bioengineering Tokyo Medical and Dental UniversityChiyoda-kuTokyoJapan Graduate School of Pharmaceutical Sciences Kyoto UniversityKyotoJapan

Inflammatory stimuli,such as a microbes or lipopolysaccharides,induce a rapid release of neutrophils from the bone marrow and promote neutrophil migration into inflamed sites to promote host ***,an excess accumulation and retention of neutrophils in inflamed tissue can cause severe tissue injuries in the later stages of *** studies have reported that both CXCL12 levels in injured lungs and its receptor,CXCR4,on accumulated neutrophils in injured lungs,increased;furthermore,these studies showed that the CXCL12/CXCR4 signaling pathway participated in neutrophil accumulation in the later stages of lipopolysaccharide(LPS)-induced lung ***,the mechanisms underlying this increase in surface CXCR4 expression in neutrophils remain *** this study,we found that surface CXCR4 expression increased in extravascular,but not intravascular,neutrophils in the lungs of LPS-induced lung injury model ***,ex vivo studies revealed that CXCL12 acted not only as a chemoattractant,but also as a suppressor of cell death for the lung neutrophils expressing ***,one of the native ligands for L-selectin,induced the increase of surface CXCR4 expression on isolated circulating neutrophils,suggesting that the activation of L-selectin may be involved in the increase in surface *** findings show that surface CXCR4 levels on neutrophils increase after extravasation into injured lungs,possibly through the activation of *** CXCL12/CXCR4 signaling pathway plays an important role in the modulation of neutrophil activity during acute lung injury,not only by promoting chemotaxis but also by suppressing cell death.

关键词： CXCL12 CXCR4 lipopolysaccharides lung injury neutrophils