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Short-term and long-term outcomes of laparoscopic vs open ileocolic resection in patients with Crohn's disease: Propensityscore matching analysis

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World Journal of Gastroenterology 2021年第41期27卷 7159-7172页

作者： shin jeong pak Young Il Kim Yong Sik Yoon Jong Lyul Lee Jung Bok Lee Chang Sik Yu Department of Colon and Rectal Surgery University of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea Department of Clinical Epidemiology and Biostatistics University of Ulsan College of MedicineAsan Medical CenterSeoul 05505South Korea

BACKGROUND Laparoscopic ileocolic resection(LICR)is the preferred surgical approach for primary ileocolic Crohn’s disease(CD)because it has greater recovery benefits than open ICR(OICR).AIM To compare short-and long-term outcomes in patients who underwent LICR and *** Patients who underwent ICR for primary CD from 2006 to 2017 at a single tertiary center specializing in CD were *** who underwent LICR and OICR were subjected to propensity-score matching *** were propensityscore matched 1:1 by factors potentially associated with 30-d perioperative *** included demographic characteristics and disease-and treatment-related *** were compared using univariate and multivariate ***-term surgical recurrence-free survival(SRFS)in the two groups was determined by the Kaplan-Meier method and compared by the log-rank *** During the study period,348 patients underwent ICR,211 by the open approach and 137 ***-score matching yielded 102 pairs of *** rate of postoperative complication was significantly lower(14%versus 32%,P=0.003),postoperative hospital stay significantly shorter(8 d versus 13 d,P=0.003),and postoperative pain on day 7 significantly lower(1.4 versus 2.3,P<0.001)in propensity-score matched patients who underwent LICR than in those who underwent *** analysis showed that postoperative complications were significantly associated with preoperative treatment with biologics[odds ratio(OR):3.14,P=0.01]and an open approach to surgery(OR:2.86,P=0.005).The 5-and 10-year SRFS rates in the matched pairs were 92.9%and 83.3%,respectively,with SRFS rates not differing significantly between the OICR and LICR *** performance of additional procedures was an independent risk factor for surgical recurrence[hazard ratio(HR):3.28,P=0.02].CONCLUSION LICR yielded better short-term outcomes and postoperative recovery than OICR,with no differences in long-ter

关键词： Crohn’s disease Laparoscopic Surgery Postoperative complications Recurrence Propensity score Retrospective study

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An Experimental Study of Condensation Heat Transfer in Sub-Millimeter Rectangular Tubes

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Journal of Thermal Science 2004年第4期13卷 350-357页

作者： jeong Seob shin Moo Hwan KIM Department of Mechanical Engineering POSTECH Pohang KoreaDepartment of Mechanical Engineering POSTECH Pohang Korea

The characteristics of local heat transfer and pressure drops were experimentally investigated using condensing R134a two-phase flow, in single rectangular tubes, with hydraulic diameter of 0.494, 0.658, and 0.972 mm. New experimental techniques were used to measure the in-tube condensation heat transfer coefficient especially for the low heat and mass flows. Tests were performed for a mass flux of 100, 200, 400, and 600 kg/m2s, a heat flux of 5 to 20 kW/m2, and a saturation temperature of 40℃. In this study, effect of heat flux, mass flux, vapor qualities, and hydraulic diameter on flow condensation were investigated and the experimental local condensation heat transfer coefficients and frictional pressure drop are shown. The experimental data of condensation Nusselt number are compared with previous correlations, most of which are proposed for the condensation of pure refrigerant in a relatively large inner diameter round tubes.

关键词： condensation hydraulic diameter rectangular in-tube multiphase flow.

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Climatic Classification over Asia during the Middle Holocene Climatic Optimum Based on PMIP Models

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Journal of Earth Science 2016年第1期27卷 123-129页

作者： Hyuntaik Oh Ho-jeong shin Center for Marine Environmental Impact Assessment National Fisheries Research and Development Institute Ocean Circulation and Climate Research Division Korea Institute of Ocean Science and Technology

When considering potential global warming projections, it is useful to understand the impact of each climate condition at 6 kyr before present. Asian paleoclimate was simulated by performing an integration of the multi-model ensemble with the paleoclimate modeling intercomparison project（PMIP） models. The reconstructed winter（summer） surface air temperature at 6 kyr before present was 0.85 oC（0.21 oC） lower（higher） than the present day over Asia, 60oE-150oE, 10oN-60oN. The seasonal variation and heating differences of land and ocean in summer at 6 kyr before present might be much larger than present day. The winter and summer precipitation of 6 kyr before present were 0.067 and 0.017 mm·day-1larger than present day, respectively. The Group B climate, which means the dry climates based on K？ppen climate classification, at 6 kyr before present decreased 17% compared to present day, but the Group D which means the continental and microthermal climates at 6 kyr before present increased over 7%. Comparison between the results from the model simulation and published paleo-proxy record agrees within the limited sparse paleo-proxy record data.

关键词： paleoclimate modeling intercomparison project (PMIP) paleoclimate global warming,Asian continent.

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Influence of the molecular structure of metal-phthalocyanine on electrocatalytic reactions

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Science China Materials 2022年第12期65卷 3324-3333页

作者： Da Sol jeong Hyeon Suk shin Jieun Yang Department of Chemistry Ulsan National Institute of Science and Technology(UNIST)50 UNIST-gilUlsan 44919Republic of Korea Department of Chemistry and Research Institute of Basic Sciences Kyung Hee University26 Kyungheedae-roDongdaemun-guSeoul 02447Republic of Korea

The demand for new catalysts for renewable energy production has become *** an alternative to metal catalysts for electrocatalysis to produce energy sources,metal-phthalocyanine(MPc)electrocatalysts have shown *** physicochemical and electrochemical properties depend on the chemical structure of the MPc and the central metal *** reviews of MPcs focused on their electrochemical performance in specific catalytic reactions,such as oxygen reduction reaction and CO_(2)reduction ***,understanding the structure of MPcs in depth is important,since their electrochemical catalytic activity is affected by structural modifications of ***,this minireview focuses on how the molecular structure of MPcs affects electrochemical catalysis.

关键词： metal-phthalocyanine oxygen reduction reaction carbon dioxide reduction reaction hydrogen evolution reaction oxygen evolution reaction electrocatalytic activities

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Let-7 miRNA and CDK4 siRNA co-encapsulated in Herceptin-conjugated liposome for breast cancer stem cells

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Asian Journal of Pharmaceutical Sciences 2020年第4期15卷 472-481页

作者： jeong Hyun shin Dae Hwan shin Jin Seok Kim College of Pharmacy Sookmyung Women’s UniversitySeoul 04310Republic of Korea College of Pharmacy Chungbuk National UniversityCheongju 28160Republic of Korea

Recently,breast cancer stem cells(BCSCs)have rapidly emerged as a novel target for the therapy of breast cancer as they play critical roles in tumor growth,maintenance,metastasis,and ***-7 miRNA is known to be downregulated in a variety of cancers,especially BCSCs,whereas CDK4 being overexpressed in human epidermal growth factor receptor 2(HER-2)overexpressing tumor *** this study,let-7 miRNA and CDK4-specific siRNA were chosen as therapeutic agents and co-encapsulated in Herceptinconjugated cationic liposomes for breast cancer *** size,zeta potential,and encapsulation efficacy of mi/siRNA-loaded PEGylated liposome conjugated with Herceptin(Her-PEG-Lipo-mi/siRNA)were 176 nm,28.1 mV,and 99.7%±0.1%,*** cellular uptake(86%)was observed by fluorescence microscopy when SK-BR-3 cells were treated with Her-PEG-Lipo-mi/***,the increased amount of let-7a mRNA and decreased amount of cellular CDK4 mRNA were observed by qRT-PCR when SK-BR-3 cells were treated with Her-PEG-Lipo-mi/siRNA,which was even more so when SK-BR-3 stem cells were used(197 vs 768 times increase for let-7a,62%vs 68%decrease for CDK4).Growth inhibition(65%)andmigration arrest(0.5%)of the cellswere achieved by the treatment of the cells with Her-PEG-Lipo-mi/siRNA,but not withmi/siRNA complex or other *** conclusion,an efficient liposomal delivery system for the combination of miRNA and siRNA to target the BCSCs was developed and could be used as an efficacious therapeuticmodality for breast cancer.

关键词： Let-7 miRNA CDK4 siRNA Liposomes Breast cancer stem cells

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Efficient and secure source authentication scheme for multicast user authentication

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Journal of Central South University 2013年第10期20卷 2741-2746页

作者： jeong Yoon-su LEE Sang-hyuk shin Seung-soo Department of Information Communication Engineering Mokwon University Department of Electrical and Electronic Engineering Xi’an Jiaotong-Liverpool University Department of Information Security Tongmyong University

Multicast technology application has been widely utilized in broadband internet. Source authentication is one of the most needs for many multicast applications transferring real-time information such as stream video and online news. Because multicast current services provided to the group members are changed dynamically, data transferring by a group member is not used by the recipient. In order to verify the identity of the sender who sent the packet and to make sure that the data have not been tampered, an optimized source authentication scheme has been proposed to transfer the authentication information not to the next-door packet. The proposed method for multiple packets authenticates the source with a limited number of electronic signatures. The proposed method can reduce overhead compared to the method by adding a digital signature for every packet. In addition, by sending the generated electronic signature to the first packet and the last packet, it prevents the loss of consecutive packets, as well as a source authentication can be provided in real-time services.

关键词： multicast packet source authentication broadband Internet

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Weighted-averaging-based classification of laser-induced breakdown spectroscopy measurements using most informative spectral lines

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Plasma Science and Technology 2020年第1期22卷 58-73页

作者： Ekta SRIVASTAVA Hyemin JANG Sungho shin Janghee CHOI Sungho jeong Euiseok HWANG School of Mechanical Engineering Gwangju Institute of Science and Technology(GIST)123 Cheomdangwagi-roBuk-guGwangju 61005Republic of Korea LGCNS LG Sciencepark El371Magokjungang 8-roGangseo-guSeoul 07795Republic of Korea Smart Manufacturing Technology Group Korea Institute of Industrial Technology89 Yangdaegiro-gilSeobuk-guCheonan-siChungcheongnam-do 31056Republic of Korea

In this study,efficient spectral line selection and wcightcd-avcraging-bascd processing schemes are proposed for the classification of laser-induced breakdown spectroscopy(UBS)*** fast on-line classification,a set of representative spectral lines arc selected ami processed relying on the information metric,instead of the time consuming full spectrum based analysis.I he most informative spectral line sets arc investigated by the joint mutual information estimation(MIR)evaluated with the Gaussian kernel density,where dominant intensity peaks associated with the concentrated components arc not necessarily most valuable for *** order to further distinguish the characteristic patterns of die LIBS measured spectrum,two-dimensional spectral images are synthesized through column-wise concatenation of the peaks along with their *** fast classification while preserv ing die effect of distinctive peak patterns,column-wise Gaussian weighted averaging is applied to die synthesized images,yielding a favorable trade off between classification performance and computational *** explore the applicability of the proposed schemes,two applications of alloy classification and skin cancer detection arc investigated with the multi-class and binary support vector machines classifiers,*** MIE measures associated with selected spectral lines in bodi applications show a strong correlation to the actual classification or detection accuracy,which enables to find out meaningful combinations of spectral *** addition,the peak patterns of the selected lines and their Gaussian weighted averaging with nciehbors of the selected peaks efficiently distineuish different classes of LIBS measured spectrum.

关键词： laser-induced breakdown spectroscopy mutual information weighted averaging alloy classification skin cancer detection

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Improvement in classification accuracy of stainless steel alloys by laser-induced breakdown spectroscopy based on elemental intensity ratio analysis

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Plasma Science and Technology 2020年第7期22卷 83-91页

作者： Sungho shin Youngmin MOON Jaepil LE Eunsung KWON Kyihwan PARK Sungho jeong School of Mechanical Engineering Gwangju Institute of Science and Technology1 Oryong-dong Buk-gu Gwangju 500-712Republic of Korea Engineering Solution Research Group Research Institute of Industrial Science and Technology67 Cheongam-ro Nam-gu Pohang-si Gyeongsangbuk-doRepublic of Korea

Laser-induced breakdown spectroscopy(LIBS) is a useful technique for accurate sorting of metal scrap by chemical composition *** this work,a method for intensity-ratiobased LIBS classification of stainless steel applicable to highly fluctuating LIBS signal conditions is *** spectral line pairs for intensity ratio calculation are selected according to elemental concentration and upper levels of emission *** is demonstrated that the classification accuracy can be significantly improved from that of full-spectra principal component analysis or intensity-based *** proposed method is considered to be suited to an industrial scrap sorting system that requires minimal maintenance and low system price.

关键词： laser-induced breakdown spectroscopy(LIBS) stainless steel classification intensity ratio

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A study on hydrogen uptake and release of a eutectic mixture of biphenyl and diphenyl ether

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Journal of Energy Chemistry 2020年第3期29卷 11-16页

作者： Munjeong Jang Byeong Soo shin Young Suk Jo jeong Won Kang Sang Kyu Kwak Chang Won Yoon Hyangsoo jeong Center for Hydrogen Fuel Cell Research Korea Institute of Science and Technology(KIST)5 Hwarang-ro 14-gilSeongbuk-guSeoul 02792Republic of Korea Divison of Energy and Environment Technology KIST SchoolKorea University of Science and Technology5 Hwarang-ro 14-gilSeongbuk-guSeoul 02792Republic of Korea Department of Chemical and Biological Engineering Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841Republic of Korea School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology50UNIST-gilUlsan 44919Republic of Korea KHU-KIST Department of Converging Science and Technology Kyung Hee University26 Kyungheedae-roDongdaemun-guSeoul 02447Republic of Korea

Hydrogen storage in Liquid Organic Hydrogen Carrier(LOHC)systems is appealing for the safe storage and distribution of excess renewable energy via existing gasoline infrastructures to *** present the eutectic mixture of biphenyl and diphenyl ether of its first use as a LOHC *** material is hydrogenated with 99%selectivity without the cleavage of C–O bond,with commercial heterogeneous catalysts,which is confirmed by nuclear magnetic spectroscopy and gas chromatography-mass *** concentration,dehydrogenation enthalpy,and thermo-neutral temperature are calculated using a density functional *** results indicate that O-atom-containing material exhibits more favorable dehydrogenation thermodynamics than that of the hydrocarbon *** H2-rich material contains6.8 wt%of gravimetric hydrogen storage capacity.A preliminary study of catalytic dehydrogenation on a continuous reactor is presented to demonstrate a reversibility of this material.

关键词： Hydrogen storage Liquid organic hydrogen carrier Diphenyl ether Dehydrogenation Thermodynamics

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Signal processing for real-time identification of similar metals by laser-induced breakdown spectroscopy

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Plasma Science and Technology 2019年第3期21卷 84-91页

作者： Sungho shin Youngmin MOON Jaepil LEE Hyemin JANG Euiseok HWANG Sungho jeong School of Mechanical Engineering Gwangju Institute of Science and Technology

Laser-induced breakdown spectroscopy(LIBS) is regarded as a promising technique for realtime sorting of scrap metals due to its capability of fast multi-elemental and in-air analysis. This work reports a method for signal processing which ensures high accuracy and high speed during similar metal sorting by LIBS. Similar metals such as aluminum alloys or stainless steel are characterized by nearly the same constituent elements with slight variations in elemental concentration depending on metal type. In the proposed method, the original data matrix is substantially reduced for fast processing by selecting new input variables(spectral lines) using the information for the constituent elements of similar metals. Specifically, principal component analysis(PCA) of full-spectra LIBS data was performed and then, based on the loading plots, the input variables of greater significance were selected in the order of higher weights for each constituent element. The results for the classification test with aluminum alloy, copper alloy,stainless steel and cast steel showed that the classification accuracy of the proposed method was nearly the same as that of full-spectra PCA, but the computation time was reduced by a factor of 20 or more. The results demonstrated that incorporating the information for constituent elements can significantly accelerate classification speed without loss of accuracy.

关键词： laser-induced breakdown spectroscopy classification similar metal reduced number of spectral lines

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