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Higher Temperatures Were Closely Associated with Higher Ambulance Transports in Takamatsu Area,Japan

Journal of Environmental Protection 2011年第1期2卷 72-75页

作者： Nobuyuki Miyatake Masaki Nakao Noriko Sakano shigeru suna Takeshi Suzue Tomohiro Hirao Department of Hygiene Faculty of MedicineKagawa UniversityMikiKagawaJapan Graduate School of Engineering Osaka City UniversityOsakaJapan Kagawa Prefectural College of Health Sciences Japan Department of Public Health Faculty of MedicineKagawa UniversityMikiKagawaJapan

The link between high temperatures and ambulance transports in Takamatsu area, Japan was investigated. Monthly observations for ambulance transports (2004-2008) were obtained from Fire Department Service in Takamatsu. Data of temperatures in Takamatsu area, Japan (2004-2008) were used by Japan Meteorological Agency. Effect of high temperatures on ambulance transports was analyzed. By using data from July to September, there were not clear differences of mean temperatures and ambulance transports among years. Ambulance transports were significantly correlated with parameters of temperatures. Correlation coefficient rate between ambulance transports and the mean temperature of maximum temperatures in a month was highest among parameters (r = 0.738, p = 0.0017). In addition, ambulance transports were also significantly correlated with the number of days over the level of 32?C in a month (r = 0.782, p = 0.0006). Higher temperatures were closely associated with higher ambulance transports in Takamatsu area, Japan.

关键词： Temperature Ambulance Transports Takamatsu Area Fire Department Service in Takamatsu Japan Meteorological Agency

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Short-term effects of di-（2-ethylhexyl） phthalate on testes,liver, kidneys and pancreas in mice

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Asian Journal of Andrology 2007年第2期9卷 199-205页

作者： Yumi Miura Munekazu Naito Maira Ablake Hayato Terayama Shuang-Qin Yi Ning Qu Lin-Xian Cheng shigeru suna Fumihiko Jitsunari Masahiro Itoh Department of Anatomy Tokyo Medical University Tokyo 160-8402 Japan Department of Histology and Embryology Xin Jiang Medical University Xinjiang 830001 China Department of Hygiene and Public Health Faculty of Medicine Kagawa University Kagawa 761-0783 Japan

Aim： To determine the biochemical effect of di-（2-ethylhexyl） phthalate （DEHP） on testes, liver, kidneys and pancreas on day 10 in the process of degeneration of the seminiferous epithelium. Methods： Diets containing 2% DEHP were given to male Crlj：CDI（ICR） mice for 10 days. The dose of DEHP was 0.90±0.52 mg/mouse/day. Their testes, livers, kidneys and pancreata were examined for detection of mono-（2-ethylhexyl） phthalate （MEHP）, nitrogen oxides （NOx） produced by peroxidation of nitric oxide （NO） with free radicals, and lipid peroxidation induced by the chain reaction of free radicals. Results： Histological observation and serum analysis showed the presence of severe sperrnatogenic disturbance, Leydig cell dysfunction, liver dysfunction and dehydration. Unexpectedly, the concentration of MEHP in the testes was extremely low compared with that in the liver. However, the concentration of the NOx in the testes was as high as the hepatic concentration. Furthermore, free radical-induced lipid peroxidation was histochemically detected in the testes but not in the liver. Conclusion： The results indicate that DEHP-induced aspermatogenesis is caused by the high sensitivity of the testicular tissues to MEHP rather than the specific accumulation or uptake of circulating MEHP into the testes.

关键词： phthalatc nitrogen oxide free radical testis

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