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A Multi-Center International Survey Related to the Nutritional Support after Hematopoietic Stem Cell Transplantation Endorsed by the ASIA Pacific Blood and Marrow Transplantation (APBMT)

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Food and Nutrition Sciences 2012年第3期3卷 417-421页

作者： shigeo fuji Takehiko Mori Vincent Lee Jessica Cheng Natalie Linton Albert Lie Navin Khattry Akio Shigematsu Naoyuki Uchida Tetsuya Eto Nguyen Duy Thang Yi-Chang Liu Deok-Hwan Yang Jin Seok Kim Joon Ho Moon Dae-Young Kim Minako Iida Ritsuro Suzuki Yoshihisa Kodera Sung-Won Kim Department of Hematology and Hematopoietic Stem Cell Transplantation National Cancer Center Hospital Tokyo Japan. Department of Hematology and Oncology Chonnam National University Hwasun Hospital Jeollanam-do Korea Department of Hematology and Oncology Hokkaido University Hospital Hokkaido Japan Department of Hematology and Oncology Kaohsiung Medical University Hospital Taiwan (China) Department of Hematology and Oncology Kyungpook National University Hospital Daegu Korea (South) Department of Hematology Asan Medical Center Seoul Korea (South) Department of Hematology Hamanomachi Hospital Fukuoka Japan Department of Hematology Toranomon Hospital Tokyo Japan Department of Hematology University Hospital Wuerzburg Wuerzburg Germany Department of HSCT Data Management and Biostatistics School of Medicine Nagoya University Nagoya Japan Department of Medical Oncology Tata Memorial Center Mumbai India Department of Medicine Queen Mary Hospital Hong Kong (China) Department of Nutrion Services St Vincent’s Hospital Sydney Sydney Australia Department of Pediatrics The Chinese University of Hong Kong Prince of Wales Hospital Hong Kong (China) Department of Promotion for Blood and Marrow Transplantation School of Medicine Aichi Medical University Nagakute Japan Division of Hematology Keio University Hos- pital Tokyo Japan Division of Hematology Yonsei University College of Medicine Severance Hospital Seoul Korea (South) Hue Regional Hematology and Blood Transfusion Center Hue Central Hospital Hue City Vietnam

Background: The nutritional support after hematopoietic stem cell transplantation (HSCT) has not been well established due to the scarcity of clinical trials. To conduct international clinical trials in Asia, we performed the questionnaire survey to investigate the current standard of nutritional support after HSCT. Method: We sent the questionnaire to the physicians nominated by the Asia Pacific Blood and Marrow Transplantation (APBMT) members of each country/ region. Result: We received 15 responses from 7 different countries/regions. The target calorie amount is 1.0 - 1.3 × basal energy expenditure (BEE) in 11 institutes when partial parenteral nutrition is used. When total parenteral nutrition (TPN) is used, the target calorie amount is 1.0 - 1.3 × BEE in 9 institutes and 1.3 - 1.5 × BEE in 4 institutes. Lipid emulsion is routinely used in 12 institutes. Multivitamins and trace elements are routinely added to TPN used in most institutes. It is still uncommon to use the immunonutrition. Blood glucose levels are routinely monitored in all institutes, but the target range varies (<110 in 2 institutes, <150 in 4 institutes, and <200 in 8 institutes). Conclusions: Basic nutritional support is similar in participating institutes. However, the target glucose level varies and the use of immunonutrition is rather rare. These points can be the theme of future clinical trials.

关键词： Stem Cell Transplantation Nutritional Support Asia Pacific Blood and Marrow Transplantation

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