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Would behavioral thermoregulation enable pregnant viviparous tropical lizards to cope with a warmer world?

Integrative Zoology 2017年第5期12卷 379-395页

作者： Saúl LÓPEZ-ALCAIDE Miguel nakamura Eric N.SMITH Enrique MARTÍNEZ-MEYER Departament of Zoology Institute of BiologyNational Autonomous University of MexicoMexico CityMexico Center for Research in Mathematics GuanajuatoMexico Amphibian and Reptile Diversity Research Center and Department of Biology University of Texas at ArlingtonArlingtonTexasUSA

Sceloporus lizards depend on external heat to achieve their preferred temperature(Tsel)for performing physiological *** both in the field and laboratory indicates that pregnant females of this Genus select body temperatures(Tb)lower than 34℃ as higher temperatures may be lethal to ***,thermoregulation is crucial for successful embryo *** the increase in global air temperature,it is expected that the first compensatory response of species that inhabit tropical climates will be behavioral *** tested whether viviparous Sceloporus formosus group lizards in the wild exhibited differences in thermoregulatory behavior to achieve the known Tsel for developing embryos regardless of local thermal *** quantified field active body temperature,thermoregulatory behavior mechanisms(time of sighting,microhabitat used and basking time)and available microhabitat thermal conditions(*** temperature)for 10 lizard species during gestation,distributed along an altitudinal *** applied both conventional and phylogenic analyses to explore whether Tb or behavioral thermoregulation could be regulated in response to different thermal *** species showed no significant differences in field Tb during gestation regardless of local thermal *** contrast,they exhibited significant differences in their behavioral thermoregulation associated with local environmental *** on these observations,the differences in thermoregulatory behavior identified are interpreted as compensatory adjustments to local thermal *** conclude that these species may deal with higher temperatures predicted for the tropics by modulating their thermoregulatory behavior.

关键词： altitudinal gradient behavior global warming Sceloporus formosus thermal stress

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Carcinosarcoma of the liver with mesenchymal differentiation

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World Journal of Gastroenterology 2007年第5期13卷 809-812页

作者： Shinichi Sumiyoshi Masataka Kikuyama Yuji Matsubayashi Fujito Kageyama Yoshihiro Ide Yoshimasa Kobayashi Hirotoshi nakamura Department of Gastroenterology Hamamatsu Rosai Hospital Hamamatsu Japan Department of Pathology Hamamatsu Rosai Hos-pital Hamamatsu Japan Second Division Department of Internal Medicine Hamamatsu University School of Medicine Hamamatsu Japan

We report an extremely rare case where a mesenchymal differentiation, especially embryonal sarcoma, was demonstrated in cholangiocarcinoma. At autopsy, a yellowish-white tumor （15 cm× 12 cm） was found in the right hepatic lobe, and there were several daughter nodules in both hepatic lobes. Histologically, most of the main tumor and all of the daughter nodules examined showed sarcomatous changes （spindle cells, pleomorphic ceils and hyalization）. Histologic examination of a part of the main tumor disclosed a focus of adenocarcinoma within the tumor. The frequent transitions between the adenocarcinomatous areas and the sarcomatous areas suggested that sarcomatous transformation occurred in the cholangiocarcinoma and then spread rapidly. Immunohistochemically, the adenocarcinomatous elements were positive for cytokeratin, carcinoembryonic antigen （CEA） and epithelial membrane antigen, and negative in the sarcomatous cells. Vimentin was positive only in the sarcomatous elements. The findings of the present case support the view that carcinosarcomas represent carcinomas that develop sarcomatous elements via metaplasia of the epithelial element.

关键词： Cholangiocarcinoma Carcinosarcoma Mesenchymal differentiation

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Spontaneous pneumothorax in a 17-year-old male patient with multiple exostoses:A case report and review of the literature

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World Journal of Orthopedics 2021年第11期12卷 945-953页

作者： Koichi nakamura Kunihiro Asanuma Akira Shimamoto Shinji Kaneda Keisuke Yoshida Yumi Matsuyama Tomohito Hagi Tomoki nakamura Motoshi Takao Akihiro Sudo Department of Orthopedic Surgery Mie University Graduate School of MedicineTsu 514-8507Mie PrefectureJapan Department of Thoracic and Cardiovascular Surgery Mie University Graduate School of MedicineTsu 514-8507Mie PrefectureJapan

BACKGROUND Multiple exostoses generally develop in the first decade of *** most frequently arise from the distal femur,proximal tibia,fibula,and proximal *** exostoses are rare,contributing to 1%-2% of all exostoses in hereditary multiple exostoses(HME).They are usually asymptomatic,but a few cases have resulted in severe thoracic *** caused by costal exostoses is rare,with only 13 previously reported *** report a new case of pneumothorax caused by costal *** SUMMARY A 17-year-old male with HME underwent surgery for removal of exostoses around his right *** months following the operation,he felt chest pain when he was playing the trumpet;however,he did not stop playing for a *** was referred to our hospital with a chief complaint of chest *** computed tomography(CT)scan revealed right pneumothorax and multiple exostoses in his right *** CT scan also revealed visceral pleura thickness and damaged lung tissues facing the exostosis of the seventh *** diagnosed that exostosis of the seventh rib induced *** exostosis resection was performed by video-assisted thoracoscopic surgery(VATS)2 wk after the *** patient’s postoperative course was uneventful,and there was no recurrence of pneumothorax for 2 *** Costal exostoses causing thoracic injuries should be resected regardless of *** must be considered in cases with apparently benign and relatively small exostoses or HME.

关键词： Costal exostosis Pneumothorax Video-assisted thoracoscopic surgery Hereditary multiple exostoses Case report Treatment

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Sport and physical exercise in sustainable mental health care of common mental disorders:Lessons from the COVID-19 pandemic

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Sports Medicine and Health Science 2023年第2期5卷 151-155页

作者： Klaus W.Lange Yukiko nakamura Andreas Reissmann Faculty of Human Sciences(Psychology Education and Sport Science)University of RegensburgRegensburgBavariaGermany

The large-scale disruptions to physical activity during the coronavirus pandemic have been found to be a leading predictor of common mental *** addition,regular physical exercise has been found to alleviate anxiety,sadness and depression during the *** findings,together with numerous studies published before the pandemic on the effects of physical activity on mental health,should be considered in the provision of mental health care following the ***-sectional research has revealed that all types of exercise and sport are associated with a reduced mental health ***,the effectiveness of exercise and sport participation in sustainable mental health care as well as the causal relationship between exercise,psychosocial health and common mental disorders merit further *** activity and sport,with their global accessibility,significant and clinically meaningful efficacy as well as virtual absence of adverse effects,offer a promising option for the promotion of mental health,including the prevention and treatment of common mental *** exercise and sport are likely to become valuable public mental health resources in the future.

关键词： Anxiety Depression Mental health Physical exercise COVID-19

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NEUTRINO MASS, MIXING, AND OSCILLATIONS

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Chinese Physics C 2016年第10期40卷 246-278页

作者： K. nakamura S.T. Petcov Kavli IPMU (WPI) U. TokyoKEK SISSA/INFN Trieste Kavli IPMU (WPI) U.Tokyo Bulgarian Academy of Sciences

The experiments with solar, atmospheric, reactor and accelerator neutrinos have provided compelling evidences for oscillations of neutrinos caused by nonzero neutrino masses and neutrino mixing. The data imply the existence of 3-neutrino mixing in vacuum. We review the theory of neutrino oscillations, the phenomenology of neutrino mixing, the problem of the nature - Dirac or Majorana, of massive neutrinos, the issue of CP violation in the lepton sector, and the current data on the neutrino masses and mixing parameters. The open questions and the main goals of future research in the field of neutrino mixing and oscillations are outlined.

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Round Robin Study on the Thermal Conductivity/Diffusivity of a Gold Wire with a Diameter of 30μm Tested via Five Measurement Methods

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Journal of Thermal Science 2022年第4期31卷 1037-1051页

作者： ABE Ryo SEKIMOTO Yuki SAINI Shirkant MIYAZAKI Koji LI Qin-Yi LI Dawei TAKAHASHI Koji YAGI Takashi nakamura Masakazu division of materials science nara institute of science and technologyikoma 630-0192japan department of mechanical and control engineering kyushu institute of technologykitakyushu 804-8550japan department ofaeronautics and astronautics kyushu universityfukuoka819-0395japan international institute for carbon-neutral energy research(wpi-i2cner) kyushu universityfukuoka 819-0395japan national metrology institute of japan national institute of advanced industrial science and technology tsukuba 305-8565japan

Since first establishing thermal measurement techniques for micrometer-scale wires,various methods have been devised and improved ***,the uncertainty of different measurements on the same sample has not yet been *** this work,a round robin test was performed to compare the thermal conductivity and thermal diffusivity measurement methods for a fine metal *** tested material was a pure gold wire,with a diameter of 30μ*** wire was cut into certain lengths and distributed to four institutions using five different measurement methods:the direct current(DC)self-heating method,the DC heating T-type method,the 3ωmethod for thermal conductivity,the scanning laser heating alternating current(AC)method,and the spot periodic heating radiation thermometry method for thermal *** completing the measurements,the reported thermal conductivity and thermal diffusivity at room temperature,i.e.,317 W·m^(-1)·K^(-1)and 128×10^(-6)m^(2)·s^(-1),respectively,were adopted as references for comparison with the measurement *** advantages and disadvantages of each method are described in terms of the effect of electrical and thermal junctions fabricated on a wire,such as an electrode,a thermocouple,and a heat *** knowledge obtained from the tested methods will be useful for selecting and designing a measurement technique for various wire-like materials.

关键词： thermal conductivity thermal diffusivity round robin test microscale wire

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Surface treatment of titanium dioxide nanopowder using rotary electrode dielectric barrier discharge reactor

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Plasma Science and Technology 2021年第10期23卷 197-203页

作者： Naw Rutha PAW Takuma KIMURA Tatsuo ISHIJIMA Yasunori TANAKA Yusuke NAKANO Yoshihiko UESUGI Shiori SUEYASU Shu WATANABE Keitaro nakamura Faculty of Electrical Engineering and Computer Science Kanazawa UniversityKanazawa 920-1192Japan Research Center for Production&Technology Nisshin Seifun Group Inc.Fujimino 356-8511Japan

Titanium dioxide(Ti O_(2))nanopowder(P-25;Degussa AG)was treated using dielectric barrier discharge(DBD)in a rotary electrode DBD(RE-DBD)*** electrical and optical characteristics were investigated during RE-DBD *** treated TiO_(2)nanopowder properties and structures were analyzed using x-ray diffraction(XRD)and Fourier-transform infrared spectroscopy(FTIR).After RE-DBD treatment,XRD measurements indicated that the anatase peak theta positions shifted from 25.3°to 25.1°,which can be attributed to the substitution of new functional groups in the TiO_(2)*** FTIR results show that hydroxyl groups(OH)at 3400 cm-1 increased *** mechanism used to modify the TiO_(2)nanopowder surface by air DBD treatment was confirmed from optical emission spectrum *** species,such as OH radical,ozone and atomic oxygen can play key roles in hydroxyl formation on the TiO_(2)nanopowder surface.

关键词： dielectric barrier discharge nanopowder reactive species rotary electrodes surface treatment titanium dioxide

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Fractalkine and TGF-β1 levels reflect the severity of chronic pancreatitis in humans

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World Journal of Gastroenterology 2008年第42期14卷 6488-6495页

作者： Mikihiko Yasuda Tetsuhide Ito Takamasa Oono Ken Kawabe Toyoma Kaku Hisato Igarashi Taichi nakamura Ryoichi Takayanagi Department of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu University Fukuoka 812-8582 Japan

MM： To clarify whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of chronic pancreatitis （CP）. This study aimed at clarifying whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of CR METHODS： Serum monocyte chemoattractant protein-1 （MCP-1）, transforming growth factor beta-1 （TGF-βI）, and soluble type fractalkine （s-fractalkine） concentrations were examined in patients with CP （n = 109） and healthy controls （n = 116）. Severity of disease was classified in patients with CP by a staging system. Relationships between stage-specific various clinical factors and serum MCP-1, TGF-β1, and s-fractalkine levels were investigated. Furthermore, 57 patients with non-alcoholic CP were similarly evaluated in order to exclude influence of alcohol intake. RESULTS： Patients with CP showed significant higher levels of serum TGF-β1 and s-fractalkine, but not MCP-1, compared to the controls. Serum TGF-β1 in the severe stage and s-fractalkine in the mild and thesevere stage of CP significantly increased compared to those of controls. However, it was observed that both TGF-β1 and s-fractalkine levels were affected by alcohol intake. In patients with non-alcoholic CP, serum TGF-β1 showed significant increase in the moderate stage of CP, and serum s-fractalkine revealed significant increase in the early stage of CP. CONCLUSION： It is suggested that the measurement of serum F-fractalkine is useful to diagnose early- stage CP. Moreover, the combined determination of both, s-fractalkine and TGF-β1, in human sera may be helpful in evaluating the severity status of CP.

关键词： Chronic pancreatitis Transforming growth factor beta-l Soluble fractalkine Monocyte chemoattractant protein-1

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Evaluation Method of the Gait Motion Based on Self-organizing Map Using the Gravity Center Fluctuation on the Sole

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International Journal of Automation and computing 2017年第5期14卷 603-614页

作者： Koji Makino Masahiro nakamura Hidenori Omori Yoshinobu Hanagata Shohei Ueda Kyosuke Nakagawa Kazuyoshi Ishida Hidetsugu Terada Graduate School of Engineering University of YamanashiKofuYamanashi 400-8511Japan Kofu Municipal Hospital KofuYamanashi 400-0832Japan

This paper describes the evaluation method of the gait motion in walk rehabilitation. We assume that the evaluation consists of the classification of the measured data and the prediction of the feature of the gait motion. The method may enable a doctor and a physical therapist to recognize the condition of the patients more easily, and increase the motivation of patient further for rehabilitation. However, it is difficult to divide the gait motion into discrete categories, since the gait motion continuously changes and does not have the clear boundaries. Therefore, the self-organizing map （SOM） that is able to arrange the continuous data on the almost continuous map is employed in order to classify them. And, the feature of the gait motion is predicted by the classification. In this study, we adopt the gravity-center fluctuation （GCF） on the sole as the measured data. First, it is shown that the pattern of the CCF that is obtained by our developed measurement system includes the feature of the gait motion. Secondly, the relation between the pattern of the GCF and the feature of the gait motion that the doctor and the physical therapist evaluate by visual inspection is considered using the SOM. Next, we describe the prediction of following features measured by numerical values： the length of stride, the velocity of walk and the difference of steps that are important for the doctor and the physical therapist to make a diagnosis of the condition of the gait motion in walk rehabilitation. Finally, it is investigated that the position of a new test data that is arranged on the map accords with the prediction. As a consequence, we confirm that the method using the SOM is often useful to classify and predict the condition of the patient.

关键词： Gait motion self-organizing map (SOM) rehabilitation evaluation method gravity center fluctuation (GCF).

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Non-robotic minimally invasive gastrectomy as an independent risk factor for postoperative intra-abdominal infectious complications: A single-center, retrospective and propensity score-matched analysis

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World Journal of Gastroenterology 2020年第11期26卷 1172-1184页

作者： Susumu Shibasaki Koichi Suda Masaya Nakauchi Kenichi nakamura Kenji Kikuchi Kazuki Inaba Ichiro Uyama Department of Surgery Fujita Health UniversityToyoake 470-1192AichiJapan Collaborative Laboratory for Research and Development in Advanced Surgical Technology Fujita Health University School of MedicineToyoake 470-1192AichiJapan

BACKGROUND Minimally invasive surgery for gastric cancer(GC) has gained widespread use as a safe curative procedure especially for early *** To determine risk factors for postoperative complications after minimally invasive gastrectomy for *** Between January 2009 and June 2019, 1716 consecutive patients were referred to our division for primary GC. Among them, 1401 patients who were diagnosed with both clinical and pathological Stage Ⅲ or lower GC and underwent robotic gastrectomy(RG) or laparoscopic gastrectomy(LG) were enrolled. Retrospective chart review and multivariate analysis were performed for identifying risk factors for postoperative *** Morbidity following minimally invasive gastrectomy was observed in 7.5% of the patients. Multivariate analyses demonstrated that non-robotic minimally invasive surgery, male gender, and an operative time of ≥ 360 min were significant independent risk factors for morbidity. Therefore, morbidity was compared between RG and LG. Accordingly, propensity-matched cohort analysis revealed that the RG group had significantly fewer intra-abdominal infectious complications than the LG group(2.5% vs 5.9%, respectively;P = 0.038), while no significant differences were noted for other local or systemic *** analyses of the propensity-matched cohort revealed that non-robotic minimally invasive surgery [odds ratio = 2.463(1.070–5.682);P = 0.034] was a significant independent risk factor for intra-abdominal infectious *** The findings showed that robotic surgery might improve short-term outcomes following minimally invasive radical gastrectomy by reducing intra-abdominal infectious complications.

关键词： Stomach neoplasms Gastrectomy Robotic surgical procedure Minimally invasive procedures Morbidity Pancreatic fistula

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