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Neighborhood garden's age shapes phyllosphere microbiota associated with respiratory diseases in cold seasons

Environmental Science and Ecotechnology 2024年第2期18卷 114-123页

作者： Chang Zhao Xinxin Liu Haoxin Tan shan Yin Lantian Su Baoming Du Muhammad Khalid Aki Sinkkonen Nan Hui School of Agriculture and Biology Shanghai Jiao Tong University800 Dongchuan Rd.200240ShanghaiChina shanghai Yangtze River Delta Eco-Environmental Change and Management Observation and Research Station Ministry of Science and TechnologyMinistry of Education800 Dongchuan Rd.200240ShanghaiChina shanghai Urban Forest Ecosystem Research Station National Forestry and Grassland Administration800 Dongchuan Rd.200240ShanghaiChina Department of Biology College of Science and TechnologyWenzhou-Kean UniversityWenzhouChina Department of Garden Technologies Horticulture TechnologiesNatural Resources Institute FinlandHelsinkiFinland Ecosystems and Environment Research Programme Faculty of Biological and Environmental SciencesUniversity of HelsinkiLahtiFinland

Neighborhood gardens serve as sensitive sites for human microbial encounters,with phyllosphere microbes directly impacting our respiratory ***,our understanding remains limited on how factors like season,garden age,and land use shape the risk of respiratory diseases(RDs)tied to these garden *** we examined the microbial communities within the phyllosphere of 72 neighborhood gardens across shanghai,spanning different seasons(warm and cold),garden ages(old and young),and locales(urban and rural).We found a reduced microbial diversity during the cold season,except for Gammaproteobacteria which exhibited an inverse *** land use influenced the microbial composition,urban and rural gardens had strikingly similar microbial ***,young gardens in the cold season hosted a substantial proportion of RDs-associated species,pointing towards increased respiratory inflammation *** essence,while newer gardens during colder periods show a decline in microbial diversity,they have an increased presence of RDs-associated microbes,potentially escalating respiratory disease *** underscores the pivotal role the garden age plays in enhancing both urban microbial diversity and respiratory health.

关键词： Neighborhood gardens Phyllosphere microbial communities Seasonal variation Garden age Respiratory diseases

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Design of a clustered data-driven array processor for computer vision

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High Technology Letters 2020年第4期26卷 424-434页

作者： shan Rui Deng Junyong Jiang Lin Zhu Yun Wu Haoyue He Feilong School of Electronic and Engineering Xi’an University of Posts and TelecommunicationsXi’an 710121P.R.China Integrated Circuit Laboratory Xi’an University of Science and TechnologyXi’an 710054P.R.China

Computer vision(CV)is widely expected to be the next big thing in emerging *** many heterogeneous architectures for computer vision ***,plenty of data need to be transferred between different structures for heterogeneous *** long data transfer delay becomes the mainly problem to limit the processing speed for computer vision *** reducing data transfer delay and fasting computer vision applications,a clustered data-driven array processor is proposed.A three-level pipelining processing element is designed which supports two-buffer data flow interface and 8 bits,16 bits,32 bits subtext parallel *** the same time,for accelerating transcendental function computation,a four-way shared pipelining transcendental function accelerator is designed,which is based on Y-intercept adjusted piecewise linear segment algorithm.A distributed shared memory structure based on unified addressing is also *** verify efficiency of architecture,some image processing algorithms are implemented on proposed *** the proposed architecture has been implemented on Xilinx ZC 706 development *** same circuitry has been synthesized using SMIC 130 nm CMOS *** circuitry is able to run at 100 *** is 26.58 mm2.

关键词： array processor data-driven adjacent interconnection distributed memory computer vision(CV)

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Pharmacokinetic characteristics of mesenchymal stem cells in translational challenges

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Signal Transduction and Targeted Therapy 2024年第10期9卷 4314-4340页

作者： Yunlong shan Mengying Zhang Enxiang Tao Jing Wang Ning Wei Yi Lu Qing Liu Kun Hao Fang Zhou Guangji Wang Key Laboratory of Drug Metabolism and Pharmacokinetics Haihe Laboratory of Cell EcosystemState Key Laboratory of Natural MedicinesChina Pharmaceutical UniversityNanjingChina Jiangsu Renocell Biotech Co.Ltd. NanjingChina

Over the past two decades,mesenchymal stem/stromal cell(MSC)therapy has made substantial strides,transitioning from experimental clinical applications to commercial *** therapies hold considerable promise for treating refractory and critical conditions such as acute graft-versus-host disease,amyotrophic lateral sclerosis,and acute respiratory distress *** recent successes in clinical and commercial applications,MSC therapy still faces challenges when used as a commercial *** detection methods have limitations,leaving the dynamic biodistribution,persistence in injured tissues,and ultimate fate of MSCs in patients *** the relationship between the pharmacokinetic characteristics of MSCs and their therapeutic effects is crucial for patient stratification and the formulation of precise therapeutic ***,the development of advanced imaging and tracking technologies is essential to address these clinical *** review provides a comprehensive analysis of the kinetic properties,key regulatory molecules,different fates,and detection methods relevant to MSCs and discusses concerns in evaluating MSC druggability from the perspective of integrating pharmacokinetics and efficacy.A better understanding of these challenges could improve MSC clinical efficacy and speed up the introduction of MSC therapy products to the market.

关键词： characteristics translational precise

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承认政治视角下的民族政策诠释

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贵州民族研究 2015年第3期36卷 10-15页

作者：乔姗姗南京大学政府管理学院江苏南京210046

各民族之间的和谐关系建立在相互平等的基础上,实现平等的核心就是对不同民族差异性给予承认而不是同化。为此,泰勒在其承认政治理论中论证了少数群体文化差异性存在的合法性。从承认政治理论视角而言,民族政策核心内容的融合并非指完... 详细信息

各民族之间的和谐关系建立在相互平等的基础上,实现平等的核心就是对不同民族差异性给予承认而不是同化。为此,泰勒在其承认政治理论中论证了少数群体文化差异性存在的合法性。从承认政治理论视角而言,民族政策核心内容的融合并非指完全一样,而是指在承认差异的基础上文化间的互动,从而构建和谐的民族关系。由于民族地区相对较为落后,国家承认差异后仅靠少数民族一己之力难以提高当地经济。为此,国家应民族地区所需制定帮扶性民族政策,引导少数民族地区发展。实践证明,我国民族政策建立在承认政治基础之上,又对其实现了创新性的超越,从而取得了民族团结和共同繁荣的预期目标。

关键词：民族政策承认政治民族关系民族发展

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Scalable Synthesis of Hierarchical Antimony/Carbon Micro-/Nanohybrid Lithium/Sodium-Ion Battery Anodes Based on Dimethacrylate Monomer

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Acta Metallurgica Sinica(English Letters) 2018年第9期31卷 910-922页

作者： Su-Zhe Liang Xiao-Yan Wang Yong-Gao Xia Sen-Lin Xia Ezzeldin Metwalli Bao Qiu Qing Ji shan-shan Yin Shuang Xie Kai Fang Lu-Yao Zheng Mei-Mei Wang Xiu-Xia Zuo Ru-Jiang Li Zhao-Ping Liu Jin Zhu Peter Müller-Buschbaum Ya-Jun Cheng North University of China Taiyuan 030051China Ningbo Institute of Materials Technology and Engineering Chinese Academy of SciencesNingbo 315201China University of Chinese Academy of Sciences Beijing 100049China Physik-Department Lehrstuhl fur Funktionelle MaterialienTechnische Universitat MunchenJames-Franck-Str.185748 GarchingGermany The University of Nottingham Ningbo China Ningbo 315100China Nano Science and Technology Institute University ofScience and Technology of ChinaSuzhou 215123China Department of Materials University of OxfordParks RdOxford OX1 3PHUK

A facile scalable synthesis of hierarchical Sb/C micro-/nanohybrid has been addressed in this work, which possesses the advantages of both micrometer and nanometer scale structures as lithium-ion battery anode. Difunctional methacrylate monomers are used as solvent and carbon source as well. Liquid precursor of antimony（III） n-butoxide is dissolved in the resin monomer solution, and further incorporated into the cross-linking polymer network via photo polymerization. Through calcination in argon/hydrogen atmosphere, antimony nanoparticles are in situ formed by carbothermal reduction, and homogeneously embedded in the in situ formed micrometer sized carbon matrix. The morphology, structure, crys- tallinity, spatial dispersion, composition, and electrochemical performance of the Sb/C micro-/nanohybrid are systemati- cally investigated. The cyclic and rate performance of the Sb/C micro-/nanohybrid anode have been effectively improved compared to the pure carbon anode. A reversible capacity of 362 mAh g-1 is achieved with a reasonable mass loading density after 300 cycles at 66 mA g-1, corresponding to capacity retention of 79%. With reducing mass loading density, the reversible capacity reaches 793 mAh g-1 after 100 cycles. Moreover, the electrochemical performance of Sb/C micro-/nanohybrid as sodium-ion battery anode is also investigated in this study.

关键词： Antimony/carbon micro-/nanohybrid Lithium-ion battery Sodium-ion battery. Anode Methacrylate Photo polymerization Thermosetting resin

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Association between fifteen risk factors and progressing ischemic stroke in the Han population of northeast China

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Chinese Medical Journal 2010年第11期123卷 1392-1396页

作者： YANG shan-shan TENG Da YOU Ding-yun SU Zhi-qiang LI Fang ZHAO Ji-yang Department of Neurology First Affiliated Hospital of HarbinMedical University Harbin Heilongjiang 150001 China Department of Statistics Harbin Medical University HarbinHeilongjiang 150086 China

Background The mortality and disability associated with progressing ischemic stroke are much higher than general ischemic stroke. This study was conducted to determine the risk factors for progressing ischemic stroke in the Han population of northeast China. Methods A total of 2511 patients with ischemic stroke within 24 hours admitted to Department of Neurology, First Affiliated Hospital of Harbin Medical University were studied, from November 2007 to May 2009. All of the patients were classified into the progressing or non-progressing group according to the scores of the Scandinavian Neurological Stroke Scale. Fifteen putative risk factors were evaluated. The influence of risk factors for progressing ischemic stroke was analyzed with the simple Logistic analysis, the multiple Logistic analysis, and the stepwise Logistic regression model. All the statistical analysis was performed by SAS 9.1. Results Totally 359 （14.3%） patients met the criteria for progressing ischemic stroke. The Logistic analysis showed that age, family stroke history, smoking history, hypertension on admission, a drop in blood pressure after admission to the hospital, high serum glucose on admission, and fever were related to progressing ischemic stroke in the Han population of northeast China. Conclusion People of the ischemic stroke with these factors are more likely to develop progressing ischemic stroke.

关键词： isehemic stroke, progressive risk factors family history fever

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An Analysis of Japan's ‘Active Pacifism'

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Contemporary International Relations 2014年第6期24卷 100-110,153页

作者： Wang shan Wang Xiangyan the Institute of Japanese Studies CICIR

Active Pacifism is the best description of Abe＇s policy push since he -most recently took office. The right wing has labeled it progressive and good for Japan. Of course, pacifism is the common goal of many people, but the word ＂active＂ reveals Japan＇ s strategic thinking. This essay will examine the background, nature and meaning of Abe＇ s Active Pacifism.

关键词：国际关系外交关系政治学中国

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Design and verification of an FPGA programmable logic element based on Sense-Switch pFLASH

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Frontiers of Information Technology & Electronic Engineering 2024年第4期25卷 485-499页

作者： Zhengzhou CAO Guozhu LIU Yanfei ZHANG Yueer shan Yuting XU No.58 Research Institute China Electronics Technology Group CorporationWuxi 214035China

This paper proposes a kind of programmable logic element(PLE)based on Sense-Switch pFLASH *** programming Sense-Switch pFLASH,all three-bit look-up table(LUT3)functions,partial four-bit look-up table(LUT4)functions,latch functions,and d flip flop(DFF)with enable and reset functions can be *** PLE uses a choice of operational logic(COOL)approach for the operation of logic functions,it allows any logic circuit to be implemented at any ratio of combinatorial logic to *** intrinsic property makes it close to the basic application specific integrated circuit(ASIC)cell in terms of fine granularity,thus allowing ASIC-like cell-based mappers to apply all their optimization *** measuring Sense-Switch pFLASH and PLE circuits,the results show that the“on”state driving current of the Sense-Switch pFLASH is about 245.52μA,and that the“off”state leakage current is about 0.1 *** programmable function of PLE works *** delay of the typical combinatorial logic operation AND3 is 0.69 ns,and the delay of the sequential logic operation DFF is 0.65 ns,both of which meet the requirements of the design technical index.

关键词： Field programmable gate array(FPGA) Programmable logic element(PLE) Boolean logic operation Look-up table Sense-Switch pFLASH Threshold voltage

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Quinosumycin,a novel anti-MRSA thioether-linked quinolinone-quinazolinone heterodimer from a marine actinomycete Streptomyces diastaticus NBU2966

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Journal of Oceanology and Limnology 2024年第6期42卷 1991-1997页

作者： Shuangling TAN Yang LIU Haonan FU Yutong XUE Fangjian FENG Jinling LI Xiaojun YAN Sitong WU shan HE Lijian DING Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center Ningbo UniversityNingbo 315211China Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University Taizhou 318053China School of Pharmaceutical Sciences Zhejiang University of TechnologyHangzhou 310014China Ningbo Institute of Marine Medicine Peking UniversityNingbo 315800China

Marine natural products offer a promising source in the development of new antibiotic *** previously undescribed compounds,including one sulfur-bearing alkaloid named quinosumycin(1)along with one chromone derivative namely chromycone(2),were discovered from an ethyl acetate(EtOAc)extract of marine Streptomyces diastaticus NBU2966 through a bioactivity-guided isolation prioritized for antimicrobial *** analysis of nuclear magnetic resonance(NMR)spectroscopy,high resolution electrospray ionization mass spectroscopy(HRESIMS)data,and electronic circular dichroism(ECD)calculations enabled the elucidation of their structures and the determination of their absolute ***(1)is the first heterodimer scaffold incorporating quinolinone and quinazolinone motifs coupled by a thioether ***,Compound 1 exhibited a relatively selective growth inhibition against methicillin-resistant Staphylococcus aureus(MRSA)with the minimal inhibitory concentration(MIC)value of 8μg/mL.

关键词： marine natural product marine Streptomyces thioether alkaloid heterodimer anti-methicillinresistant Staphylococcus aureus(anti-MRSA)

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Japan’s Political Development in the Later Period of the Abe Administration and the Sino-Japanese Relationship

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Contemporary International Relations 2019年第3期29卷 96-120页

作者： Wang shan Meng Xiaoxu Institute for Japanese Studies CICIR Department of International Politics University of International Relations(UIR)

With Shinzo Abe's re-election as the president of Japan's Liberal Democratic Party (LDP), the LDP regime appears to have entered on a stable trend of long-term governance. This also marks a later phase of the Abe administration has solidified its later phase, following Abe's second rise to power. The supremacy of the LDP and the administration of the basket of economic policies termed Abenomics have produced initial effects, and the overall climate of political opinion in Japan remains largely conservative, all factors favorable the continuance of Abe's regime. A major task in the future to cement AbeJ s political legacy would be amendment of Japan’ s pacifist constitution. Abe’ s political and security policies are likely not to change, namely, the promotion of multilateral cooperation in the US-Japan alliance, a moderate adjustment of Japan's China policy, and a return to utilitarian diplomacy to maximize Japan’s national interests. Thanks to the return of the Sino-Japanese relationship to the right track, the healthy development of bilateral relations depends on the consolidation of the political foundation, deepening mutually beneficial cooperation, and constructively managing and controlling disagreement.

关键词： Japanese politics Sino-Japanese relationship Abe administration foreign strategy

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