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Survival improvement and prognostic factors in recent management of extrahepatic cholangiocarcinoma:A single-center study

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Hepatobiliary & Pancreatic Diseases International 2020年第2期19卷 153-156页

作者： jung wan Choe Hyo jung Kim Jae Seon Kim Division of gastroenterology Department of Internal MedicineKorea University Ansan HospitalKorea University College of Medicine516 Gojan-dongDanwon-guAnsan-siGyeonggi-do15355Korea Division of gastroenterology Department of Internal MedicineKorea University Guro HospitalKorea University College of Medicine148 Gurodong-roGuro-guSeoul 08308Korea

Background:Cholangiocarcinoma was considered as a dismal disease with very poor prognosis until *** is increasingly found due to increased life *** surgical and medical management were advanced recently,data on the prognosis,especially extrahepatic cholangio-carcinoma(ECC),were *** study aimed to identify clinicopathologic features and prognosis of patients with ***:Patients followed up and diagnosed with ECC between January 2014 and December 2016 at a tertiary hospital were included,whereas those with intrahepatic cholangiocarcinoma,gallbladder cancer,and ampullary cancer were ***:A total of 83 patients were followed after the treatment(49 men and 34 women;median age 73.3 years).Cancer location was classified as distal common bile duct(25 patients),proximal com-mon bile duct(24 patients),common hepatic duct(20 patients),and hilar(14 patients).About 14.5%of patients had history of another malignant neoplasm,and 24.1%patients had chronic ***-cal resection was performed in 54 patients(65%)and dysplasia was combined in 63%(34/54).Adjuvant chemotherapy was performed in 54%(29/54),but only 7 underwent palliative chemotherapy in 29 non-surgical *** median overall survival in all patients was 30.9 *** analyzing the treatment modality,median survival of adjuvant chemotherapy,surgery only,palliative chemotherapy,and support-ive care groups were 42.9,30.9,12.0,and 8.9 months,respectively(Pgression analy-sis of survival,age,surgical resection,chemotherapy,and comorbidity were significant prognostic factors,and the comorbidity was the only significant prognostic factor in the multivariable analysis(hazard ratio[HR]=2.80;95%CI:1.32–5.95;P=0.007).In a subgroup analysis of surgical patients,the presence of dysplasia was a favorable prognostic factor in the multivariable analysis(HR=0.29;95%CI:0.09–0.91;P=0.033).Conclusions:The overall survival of patients with ECC wa

关键词： Cholangiocarcinoma Survival Prognosis

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Self-Efficacy Triggers Psychological Appraisal Mechanism for Mindset Shift

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International Journal of Mental Health Promotion 2021年第1期23卷 57-73页

作者： Song Ching Fan Hui-Chuan Shih Hui-Chu Tseng Kuei-Feng Chang Wei-Chin Li An Shin shia Lingnan Normal University Zhanjiang524048China Chaoyang University of Technology Taichung City413310Taiwan TransWorld University Douliu City640Taiwan guangzhou University Guangzhou Higher Education Mega CenterGuangzhou510006China Chang jung Christian University Tainan City71101Taiwan

This paper talks about how to insist staying in changed mindset based on the assigned cognitive reframing principles,andfinally the changed mindset become a forever psychological status by PSI model proposed by this study.P is the cognitive reframing principle of positive psychology,happiness in this case;S is self-efficacy,which plays the important role in maintaining the stress taker to psychologically stay in the changed mindset in the long run.I represent of insisting power,the mental toughness to against the adverse negative *** university students’stress coping skills through the psychological dynamics formed by cognitive reframing principles of positive psychology,self-efficacy,and mental toughness will help them effectively deal with stressful *** study aims to reduce university students’stress level by increasing their ability to cope with stress,and improving their life satisfaction by understanding the mechanism for mindset-shift of university students and proposal of the new PSI reframing model for creating a new path to let students view stressors as challenge,not *** adopted in this study include cognitive reframing principles,appraisal theory,hindrance-challenge theory,cognitive reframing the *** the introduction section,the authors will clearly depict the logics for utilization of these theories in supporting the proposed PSI *** research was divided into two *** 1 postulated that cognitive reframing principles of positive psychology,self-efficacy,and mental toughness have a positive mediating effect in the causal relationship between university students’stress level and life *** revealed that stressful life events negatively predict the level of ***,PP,SE,and MT exert a positive and significant impact on the relationship between stressful life events and *** strengthens individuals’perception of stressful life events as chal-lenges instead of *** study s

关键词： Life satisfaction mental toughness cognitive reframing principles positive psychology self-efficacy stress

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3-D geochemical interpolation guided by geophysical inversion models

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geoscience Frontiers 2021年第3期12卷 132-145页

作者： Tom Horrocks Eun-jung Holden Daniel Wedge ChrisWijns Centre for Exploration Targeting.School of Earth Sciences University of Western AustraliaCrawleyWA 6009Australia

3-D geochemical subsurface models,as constructed by spatial interpolation of drill-core assays,are valuable assets across multiple stages of the mineral industry's ***,the accuracy of such models is limited by the spatial sparsity of the underlying drill-core,which samples only a small fraction of the *** limitation can be alleviated by integrating collocated 3-D models into the interpolation process,such as the 3-D rock property models produced by modern geophysical inversion procedures,provided that they are sufficiently resolved and correlated with the interpolation *** standard machine learning algorithms are capable of predicting the target property given these data,incorporating spatial autocorrelation and anisotropy in these models is often not *** propose a gaussian process regression model for 3-D geochemical interpolation,where custom kernels are introduced to integrate collocated 3-D rock property models while addressing the trade-off between the spatial proximity of drill-cores and the similarities in their collocated rock properties,as well as the relative degree to which each supporting 3-D model contributes to *** proposed model was evaluated for 3-D modelling of Mg content in the Kevitsa Ni-Cu-PgE deposit based on drill-core analyses and four 3-D geophysical inversion *** the inversion models improved the regression model's likelihood(relative to a purely spatial gaussian process regression model)when evaluated at held-out test holes,but only for moderate spatial scales(100 m).

关键词： Machine learning gaussian process regression Kriging geophysical inversion Interpolation

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A new database of building-space-specific internal loads and load schedules for performance based code compliance modeling of commercial buildings

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Building Simulation 2024年第6期17卷 877-892页

作者： Yunyang Ye Cary A.Faulkner Wooyoung jung Jian Zhang Eli Brock Pacific Northwest National Laboratory RichlandWA99354USA University of Pittsburgh PittsburghPA15260USA

Building-level loads and load schedules prescribed by current modeling rules save modelers time and provide standards during whole building performance ***,recent studies show that they sometimes insufficiently capture the entire building performance due to the varied loads and load schedules for different space *** a solution to this issue,this paper presents a database of default building-space-specific loads and load schedules for use in energy modeling,and in particular code compliance modeling for commercial *** existing sets of default loads and load schedules are reviewed and the challenges behind using them for specific research topics are ***,the proposed method to develop the building-space-specific loads and load schedules is *** that,the database for these building-space-specific loads and load schedules is *** addition,one case is studied to demonstrate the applications of these loads and load *** this case study,three methods are used to develop building energy models:space-specific(using knowledge of the distribution and location of space types and applying the space-specific data in the developed database),building-level(assuming a lack of knowledge of the space types and using the building-level data in the developed database),and calculated-ratio(assuming knowledge of the distribution of space types but not their locations and calculating weighted average values based on the space-specific data in the developed database).The energy results simulated by using these three methods are compared,which shows building-level methods can produce significantly different absolute energy and energy savings results than the results using space-specific ***,this paper discusses the application scope and maintenance of this new database.

关键词： load load schedule space specific building energy modeling code compliance

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Prunus genetics and applications after de novo genome sequencing:achievements and prospects

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Horticulture Research 2019年第1期6卷 1222-1246页

作者： Maria JoséAranzana Véronique Decroocq Elisabeth Dirlewa.ger Iban Eduardo Zhong Shan gao Ksenija gasic Amy Iezzoni Sook jung Cameron Peace Humberto Prieto Ryutaro Tao Ignazio Verde Albert g.Abbott Pere Arús IRTA Centre de Recerca en Agrigenòmica CSIC-IRTA-UAB-UBCampus UABEdifici CRAGCerdanyola del Vallès(Bellaterra)08193 BarcelonaSpain UMR 1332 BFP INRAUniversity of BordeauxA3C and Virology Teams33882 Villenave-d’Ornon CedexFrance Allergy Research Center Zhejiang University310058 HangzhouChina Clemson University ClemsonSC 29634USA Department of Horticulture Michigan State University1066 Bogue StreetEast LansingMI 48824-1325USA Department of Horticulture Washington State UniversityPullmanWA 99164-6414USA Biotechnology Laboratory La Platina Research StationInstituto de Investigaciones AgropecuariasSanta Rosa11610 La PintanaSantiagoChile Laboratory of Pomology Graduate School of AgricultureKyoto UniversityKyoto 606-8502Japan Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria(CREA)-Centro di ricerca Olivicoltura Frutticoltura e Agrumicoltura(CREA-OFA)RomeItaly University of Kentucky 106 T.P.Cooper HallLexingtonKY 40546-0073USA

Prior to the availability of whole-genome sequences,our understanding of the structural and functional aspects of Prunus tree genomes was limited mostly to molecular genetic mapping of important traits and development of EST *** public release of the peach genome and others that followed,significant advances in our knowledge of Prunus genomes and the genetic underpinnings of important traits *** this review,we highlight key achievements in Prunus genetics and breeding driven by the availability of these whole-genome *** the structural and evolutionary contexts,we summarize:(1)the current status of Prunus whole-genome sequences;(2)preliminary and ongoing work on the sequence structure and diversity of the genomes;(3)the analyses of Prunus genome evolution driven by natural and man-made selection;and(4)provide insight into haploblocking genomes as a means to define genome-scale patterns of evolution that can be leveraged for trait selection in pedigree-based Prunus tree breeding programs ***,we summarize recent and ongoing work that leverages whole-genome sequences to identify and characterize genes controlling 22 agronomically important Prunus *** include phenology,fruit quality,allergens,disease resistance,tree architecture,and ***,we explore the application of sequence-based marker-assisted breeding technologies and other sequence-guided biotechnological approaches for Prunus crop ***,we present the current status of publically available Prunus genomics and genetics data housed mainly in the genome Database for Rosaceae(gDR)and its updated functionalities for future bioinformatics-based Prunus genetics and genomics inquiry.

关键词： Prunus breeding achievements

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Rheological properties of rare earth minerals flotation pulp in the presence of anions

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Journal of Rare Earths 2024年第11期42卷 2172-2182,I0007页

作者： Moonchul jung Bogale Tadesse Craig Dick Alex Logan Laurence Dyer Boris Albijanic Western Australia School of Mines Curtin UniversityKalgoorlieWA 6430Australia Lynas Rare Earths Ltd Mt Weld Elora RoadLavertonWA 6440Australia

water quality has been found to significantly influence the flotation operations due to the alteration of surface properties of *** effect of cations on the flotation of RE minerals has been studied,however,there are still very limited information regarding the effect of *** present study examined the impact of specific anions such as Cl^(-),SO_(4)^(2-),and HCO_(3)^(-)on the flotation performance of rare earth(RE) *** study integrates flotation experiments,rheology measurements,entrainment experiments,zeta potential measurements and settling *** is observed that an increase in the concentration of these anions lead to a decrease in the recovery of RE minerals and an increase in the recovery of FeO minerals and thus negatively affecting flotation *** adverse effect is most pronounced with Cl^(-)and least noticeable with HCO_(3)^(-).An increase in the non-selective entrainment of gangue minerals is observed when the flotation pulp has higher *** reduction in the zeta potential of fine particles in the presence of these results in a higher pulp viscosity due to increased attractive forces between *** findings were verified by settling experiments and calculations based on the DLVO theory.

关键词： Flotation Rare earth ore Anions Pulp rheology Entrainment DLVO theory

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Electrochemical water Splitting:Bridging the gaps Between Fundamental Research and Industrial Applications

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Energy & Environmental Materials 2023年第5期6卷 22-42页

作者： Hainan Sun Xiaomin Xu Hyunseung Kim WooChul jung Wei Zhou Zongping Shao Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Korea wa School of Mines:Minerals Energy and Chemical Engineering(waSM-MECE) Curtin UniversityPerthWestern Australia 6102Australia State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China

Electrochemical water splitting represents one of the most promising technologies to produce green hydrogen,which can help to realize the goal of achieving carbon *** substantial efforts on a laboratory scale have been made for understanding fundamental catalysis and developing high-performance electrocatalysts for the two half-reactions involved in water electrocatalysis,much less attention has been paid to doing relevant research on a larger *** example,few such researches have been done on an industrial ***,we review the very recent endeavors to bridge the gaps between fundamental research and industrial applications for water *** begin by introducing the fundamentals of electrochemical water splitting and then present comparisons of testing protocol,figure of merit,catalyst of interest,and manufacturing cost for laboratory and industry-based water-electrolysis *** attention is paid to tracking the surface reconstruction process and identifying real catalytic species under different testing conditions,which highlight the significant distinctions of corresponding electrochemical reconstruction *** in catalyst designs for industry-relevant water electrolysis are also summarized,which reveal the progress of moving the practical applications forward and accelerating synergies between material science and *** and challenges of electrocatalyst design strategies are proposed finally to further bridge the gaps between lab-scale research and large-scale electrocatalysis applications.

关键词： electrocatalyst design electrochemical water splitting gaps and bridges laboratory scale and industrial scale

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Advanced electrocatalysts with unusual active sites for electrochemical water splitting

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InfoMat 2024年第1期6卷 65-82页

作者： Hainan Sun Xiaomin Xu Hyunseung Kim Zongping Shao WooChul jung Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea wa School of Mines:Minerals Energy and Chemical Engineering(waSM-MECE) Curtin UniversityPerthWestern AustraliaAustralia

Electrochemical water splitting represents a promising technology for green hydrogen *** design advanced electrocatalysts,it is crucial to identify their active sites and interpret the relationship between their structures and *** extensively studied as electrocatalysts include noble-metal-based(e.g.,Ru,Ir,and Pt)and non-noble-metal-based(e.g.,3d transition metals)***,advancements in characterization techniques and theoretical calculations have revealed novel and unusual active *** present review highlights the latest achievements in the discovery and identification of various unconventional active sites for electrochemical water splitting,with a focus on state-of-the-art strategies for determining true active sites and establishing structure–activity ***,we discuss the remaining challenges and future perspectives for the development of next-generation electrocatalysts with unusual active *** presenting a fresh perspective on the unconventional reaction sites involved in electrochemical water splitting,this review aims to provide valuable guidance for the future study of electrocatalysts in industrial applications.

关键词： electrochemical water splitting hydrogen evolution reaction oxygen evolution reaction structure–activity relationship unusual active sites

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Application of Internet of Things Micropower Smart Switch in Temperature Monitoring

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Journal of Electronic Science and Technology 2022年第3期20卷 319-330页

作者： Yeong-Chin Chen Hao-Cheng Yang Long-Chen Hung Cheng-jung Ku the Department of Computer Science and Information Engineering Asia UniversityTaichung 41354 the Department of Electronic Engineering Lungh-Wa University of Science and TechnologyTaoyuan 333326

This study uses the smart phone with the Android system to construct a cloud-side smart switch system in the client-server architecture with the Android open platform system, using microprocessors(MCU 16F690) as the thermostat controller and combined with Raspberry Pi. The computing technology extends the control of the constant temperature from the local to the cloud, allowing the user to view the temperature status recorded by the cloud server using the smart phone application(App) or web browser. It can even remotely control the heating power of the smart switch for the heating device in the Internet control environment and use the proportional-integral-derivative(PID) control and the pulse-width modulation(PWM) technology to achieve intelligent constant temperature *** proposed control system uses the expert PID control as the core to calculate the duty cycle of the PWM signal to control the power output of the smart switch for the constant temperature water tank. The experiment results verify the effectiveness of the proposed system.

关键词： Proportional-integral-derivative(PID) pulse-width modulation(PWM) Raspberry Pi smart switch

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Preface to the Special Issue:Towards Improving Understanding and Prediction of Arctic Change and its Linkage with Eurasian Mid-latitude Weather and Climate

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Advances in Atmospheric Sciences 2018年第1期35卷 1-4页

作者： Xiangdong ZHANg Thomas jung Muyin wa.g Yong LUO Tido SEMMLER Andrew ORR International Arctic Research Center University of Alaska FairbanksFairbanks AK 99775USA Alfred Wegener Institute Helmholtz Centre for Polar and Marine ResearchBremerhaven 27570Germany joint Institute for the Study of the Atmosphere and Ocean University of WashingtonSeattleWA 98115USA Center for Earth System Science Tsinghua UniversityBeijing 100084China British Antarctic Survey Cambridge CB3 0ETUK

The dramatic changes in the Arctic climate system during recent decades are one of the most prominent features of global climate *** most striking and fundamental characteristics are the amplified near-surface warming at a rate twice the global average since the mid 20th century(e.g.,Blunden and Arndt,2012;Huang et al.,2017),and the rapid

关键词： Preface to the Special Issue:Towards Improving Understanding and Prediction of Arctic Change and Its Linkage with Eurasian Mid-latitude Weather and Climate

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