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Design parameter optimization method for a prestressed steel structure driven by multi-factor coupling

Frontiers of Structural and Civil Engineering 2024年第7期18卷 1066-1083页

作者： Guo-Liang shi Zhan-Sheng LIU De-Chun LU Qing-Wen zhang Majid DEZHKAM ze-Qiang WANG Faculty of Architecture Civil and Transportation EngineeringBeijing University of TechnologyBeijing 100124China The Key Laboratory of Urban Security and Disaster Engineering of the Ministry of Education Beijing University of TechnologyBeijing 100124China Beijing Building Construction Research Institute Co. Ltd.Beijing 100039China

To achieve efficient structural design,it is crucial to reduce the cost of materials while ensuring structural *** study proposes an optimization method for design parameters(DPs)in a prestressed steel structure driven by multi-factor *** accomplish this,a numerical proxy model of prestressed steel structures is established with integration of DPs and mechanical parameters(MPs).A data association-parameter analysis-optimization selection system is established.A correlation between DPs and MPs is established using a back propagation(BP)neural *** correlation provides samples for parameter analysis and optimization *** are used to characterize the safety of the *** on the safety grade analysis,the key DPs that affect the mechanical properties of the structure are obtained.A mapping function is created to match the MPs and the key *** optimal structural DPs are obtained by setting structural materials as the optimization objective and safety energy as the constraint *** theoretical model is applied to an 80-m-span gymnasium and verified with a scale test physical *** MPs obtained using the proposed method are in good agreement with the experimental *** with the traditional design method,the design cycle can be shortened by more than 90%.Driven by the optimal selection method,a saving of more than 20% can be achieved through reduction of structural material ***,the cross-sectional dimensions of radial cables have a substantial influence on vertical *** initial tension and cross-sectional size of the upper radial cable exhibit the most pronounced impact on the stress distribution in that *** initial tension and cross-sectional size of the lower radial cable hold the greatest sway over the stress distribution in that cable.

关键词： structure design association relationship performance analysis optimum selection experimental verification

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Deep Synchronization Control of Grid-Forming Converters:A Reinforcement Learning Approach

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IEEE/CAA Journal of Automatica Sinica 2025年第1期 273-275页

作者： Zhuorui Wu Meng zhang Bo Fan Yang shi Xiaohong Guan the School of Cyber Science and Engineering Xi'an Jiaotong University the Department of Mechanical Engineering University of Victoria

Dear Editor,This letter proposes a deep synchronization control(DSC) method to synchronize grid-forming converters with power grids. The method involves constructing a novel controller for grid-forming converters based on the stable deep dynamics model. To enhance the performance of the controller, the dynamics model is optimized within the deep reinforcement learning(DRL) framework. Simulation results verify that the proposed method can reduce frequency deviation and improve active power responses.

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Recent advances in wave energy converters based on nonlinear stiffness mechanisms

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Applied Mathematics and Mechanics(English Edition) 2022年第7期43卷 1081-1108页

作者： Xiantao zhang Haicheng zhang Xiao ZHOU ze SUN State Key Laboratory of Ocean Engineering Shanghai Jiao Tong UniversityShanghai 200240China College of Mechanical and Vehicle Engineering Hunan UniversityChangsha 410082China China ship Scientific Research Center Wuxi 214082Jiangsu ProvinceChina

Wave energy is one of the most abundant renewable clean energy sources,and has been widely studied because of its advantages of continuity and low seasonal ***,its low capture efficiency and narrow capture frequency bandwidth are still technical bottlenecks that restrict the commercial application of wave energy converters(WECs).In recent years,using a nonlinear stiffness mechanism(NSM)for passive control has provided a new way to solve these technical *** literature review focuses on the research performed on the use of nonlinear mechanisms in wave energy device utilization,including the conceptual design of a mechanism,hydrodynamic models,dynamic characteristics,response mechanisms,and some examples of experimental ***,future research directions are discussed and recommended.

关键词： wave energy efficiency nonlinear stiffness hydrodynamics bistable

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Genome-wide analysis of the synonymous codon usage patterns in apple

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Journal of Integrative Agriculture 2016年第5期15卷 983-991页

作者： LI Ning SUN Mei-hong JIANG ze-sheng SHU Huai-rui zhang shi-zhong State Key Laboratory of Crop Biology Shandong Agricultural University

Apple（Malus×domestica） has been proposed as an important woody plant and the major cultivated fruit trees in temperate regions. Apple whole genome sequencing has been completed, which provided an excellent opportunity for genome-wide analysis of the synonymous codon usage patterns. In this study, a multivariate bioinformatics analysis was performed to reveal the characteristics of synonymous codon usage and the main factors affecting codon bias in apple. The neutrality, correspondence, and correlation analyses were performed by Codon W and SPSS（Statistical Product and Service Solutions） programs, indicating that the apple genome codon usage patterns were affected by mutational pressure and selective constraint. Meanwhile, coding sequence length and the hydrophobicity of proteins could also influence the codon usage patterns. In short, codon usage pattern analysis and determination of optimal codons has laid an important theoretical basis for genetic engineering, gene prediction and molecular evolution studies in apple.

关键词： apple the synonymous codon usage patterns codon bias RSCU

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Numerical analysis of loess and weak intercalated layer failure behavior under direct shearing and cyclic loading

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Journal of Mountain Science 2020年第11期17卷 2796-2815页

作者： zhang ze-lin WANG Tao College of Water Resources and Civil Engineering China Agricultural UniversityBeijing 100083China Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China

The mechanical behavior of the joints inside a loess layer is greatly important in weak intercalation studies owing to its involvement in a wide range of landslides in the loess region in *** shear behavior of the joints in the loess stratum during direct shear and cyclic loadings was investigated using the PFC2D discrete element *** mudstone and mudstone with weak intercalated layer materials were subjected to direct testing,and cyclic shear tests were conducted with consideration to the influence of normal stress and shear *** macroscopic properties and damage patterns were obtained for six numerical configurations;namely,loess-weathered mudstone with 0°,10°,and-10°joints and weathered mudstone with 0°,10°,and-10°weak intercalated *** numerical test results revealed that,in the direct shear tests,the shear stress and shear displacement of the samples increased with the normal *** the cyclic shear tests with a total cycle number N=20,the shear stress-shear strain curve of the six different configurations exhibited a hysteresis *** numerical tests also revealed that,under cyclic shear,the normal stress and shear velocity affected the shear *** degree of damage increased as the shear velocity decreased from 0.1 mm/s to 0.005 mm/s for all six numerical *** with the damage pattern of the direct shear tests,the damage of the cyclic shear tests mainly comprised shear cracks and fractures,some shaking consolidation settlement and fewer shear strain occurred around the *** the direct shear tests,more compression cracks and fractures occurred in the *** damage mainly developed along the joints,and shearing-off damage *** results obtained by this study further elucidate the failure mechanism and microscopic damage response of the joints in the loess stratum in Northwest China.

关键词： Loess Mudstone Weak intercalated layer Direct shear test Cyclic shear test PFC2D

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ImSpiRE: image feature-aided spatial resolution enhancement method

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Science China Life Sciences 2025年第1期 272-283页

作者： Yuwei Hua Yizhi zhang Zhenming Guo Shan Bian Yong zhang State Key Laboratory of Cardiovascular Diseases and Medical Innovation Center Institute for Regenerative MedicineDepartment of NeurosurgeryShanghai East HospitalShanghai Key Laboratory of Signaling and Disease ResearchFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji University

The resolution of most spatially resolved transcriptomic technologies usually cannot attain the single-cell level, limiting their applications in biological discoveries. Here, we introduce ImSpiRE, an image feature-aided spatial resolution enhancement method for in situ capturing spatial transcriptome. Taking the information stored in histological images, ImSpiRE solves an optimal transport problem to redistribute the expression profiles of spots to construct new transcriptional profiles with enhanced resolution, together with extending the gene expression profiles into unmeasured regions. Applications to multiple datasets confirm that ImSpiRE can enhance spatial resolution to the subspot level while contributing to the discovery of tissue domains, signaling communication patterns, and spatiotemporal characterization.

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Targeting Epac2 and GluA3-containing AMPARs:a novel therapeutic strategy for Alzheimer's disease

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Neural Regeneration Research 2025年第11期20卷 3223-3224页

作者： Tong zhang Martina Schmidt Department of Molecular Pharmacology Groningen Research Institute of PharmacyUniversity of GroningenGroningenThe Netherlands School of Pharmacy Tianjin Medical UniversityTianjinChina

Alzheimer's disease(AD)is a neurodegenerative disease that manifests progressive decline in memory and *** the early stage of AD,memory retrieval is impaired preceding memory acquisition and consolidation(Roy et al.,2016).Prior to the onset of symptoms,pathological amyloid-β(Aβ)plagues and tau protein tangles accumulate in extracellular and intracellular spaces,respectively,leading to *** these hallmark pathologies,Aβ is proposed to be the primary etiology by triggering a cascade of pathogenic events,including neuroinflammation,oxidative stress,tau hyperphosphorylation,synaptic/neuronal dysfunction,and neuronal death(zhang et al.,2023b).

关键词： Alzheimer impaired Aβ

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Redshift drift constraints on holographic dark energy

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Science China(Physics,Mechanics & Astronomy) 2017年第3期60卷 80-86页

作者： Dong-ze He Jing-Fei zhang Xin zhang Department of Physics College of Sciences Northeastern University Center for High Energy Physics Peking University

The Sandage-Loeb （SL） test is a promising method for probing dark energy because it measures the redshift drift in the spectra of Lyman-o： forest of distant quasars, covering the ＂redshift desert＂ of 2 ≤ z ≤ 5, which is not covered by existing cosmological observations. Therefore, it could provide an important supplement to current cosmological observations. In this paper, we explore the impact of SL test on the precision of cosmological constraints for two typical holographic dark energy models, i.e., the original holographic dark energy （HDE） model and the Ricci holographic dark energy （RDE） model. To avoid data inconsistency, we use the best-fit models based on current combined observational data as the fiducial models to simulate 30 mock SL test data. The results show that SL test can effectively break the existing strong degeneracy between the present-day matter density Ωm0 and the Hubble constant 1-1o in other cosmological observations. For the considered two typical dark energy models, not only can a 30-year observation of SL test improve the constraint precision of Ωm0 and h dramatically, but can also enhance the constraint precision of the model parameters c and α significantly.

关键词： redshift drift Sandage-Loeb test holographic dark energy Ricci dark energy cosmological constraints

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Serine protease inhibitors LmSPN2 and LmSPN3 co-regulate embryonic diapause in Locusta migratoria manilensis(Meyen)via the Toll pathway

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Journal of Integrative Agriculture 2023年第12期22卷 3720-3730页

作者： FENG shi-qian zhang Neng CHEN Jun zhang Dao-gang ZHU Kai-hui CAI Ni TU Xiong-bing zhang ze-hua State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193P.R.China

Female adults of the migratory locust,Locusta migratoria manilensis(Meyen),can sense seasonal photoperiod changes,which induces embryonic diapause as a key strategy to *** protease inhibitor genes(SPNs)were thought to play key roles during diapause,while few SPNs were functionally ***2 was one of those genes differentially expressed between diapause and non-diapause eggs;however,its biological function remained to be ***,we conducted RNAi knockdown of LmSPN2,resulting in a significant decrease of the egg diapause rate by 29.7%.Using yeast two-hybrid assays,co-immunoprecipitation,and pull-down methods,we found an interaction between LmSPN2 and LmSPN3,which was proved to be mediated by a glutamate(E331)binding site of *** knockdown of LmSPN3 resulted in a significant increase in diapause rate by 14.6%,indicating an inverse function of LmSPN2 and LmSPN3 on diapause *** knockdown of two SPN genes resulted in a 26.4%reduction in diapause rate,indicating that LmSPN2 was the dominant regulatory ***,we found four Toll pathway genes(easter,spätzle,pelle,and dorsal)upregulated significantly after the knockdown of LmSPN2 while downregulated after the knockdown of ***,we speculate that two SPNs regulate diapause through the Toll *** results indicated that LmSPN2 positively regulates locust egg entry into diapause,while LmSPN3 is a negative regulator of embryonic commitment to *** interaction is mediated by the binding site of E331 and influences egg diapause through the Toll *** mechanistic understanding of diapause regulation expands our understanding of insect developmental regulation and provides functional targets for developing locust management strategies.

关键词： Locusta migratoria insect diapause regulation Toll pathway protein interaction serine protease inhibitor

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Ammonia pyrolysis oxidation excited by nanosecond pulsed discharge:Global/fluid models hybrid solution

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Journal of Energy Chemistry 2025年第1期100卷 385-396页

作者： Mingming zhang Hanyu Wu Qi Chen Jiaxin Yang Bonan Liu School of Mechanical Electronic and Control Engineering Beijing Jiaotong University China University of Petroleum

The kinetic characteristics of plasma-assisted oxidative pyrolysis of ammonia are studied by using the global/fluid models hybrid solution ***,the stable products of plasma-assisted oxidative pyrolysis of ammonia are *** results show that the consumption of NH3/O2and the production of N2/H2change linearly with the increase of voltage,which indicates the decoupling of nonequilibrium molecular excitation and oxidative pyrolysis of ammonia at low ***,the detailed reaction kinetics mechanism of ammonia oxidative pyrolysis stimulated by a nanosecond pulse voltage at low pressure and room temperature is *** on the reaction path analysis,the simplified mechanism is *** detailed and simplified mechanism simulation results are compared with experimental data to verify the accuracy of the simplified ***,based on the simplified mechanism,the fluid model of ammonia oxidative pyrolysis stimulated by the nanosecond pulse plasma is established to study the pre-sheath/sheath behavior and the resultant consumption and formation of key *** results show that the generation,development,and propagation of the pre-sheath have a great influence on the formation and consumption of *** consumption of NH3by the cathode pre-sheath is greater than that by the anode pre-sheath,but the opposite is true for OH and O（1S）.However,within the sheath,almost all reactions do not ***,by changing the parameters of nanosecond pulse power supply voltage,it is found that the electron number density,electron current density,and applied peak voltages are not the direct reasons for the structural changes of the sheath and ***,the discharge interval has little effect on the sheath structure and gas mixture *** research results of this paper not only help to understand the kinetic promotion of non-equilibrium excitation in the process of oxidative pyrolysis but also help to explore th

关键词： Nanosecond pulsed discharge Ammonia Oxidative pyrolysis Fluid model Global model

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