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Predictive Value of BRAF^V600E Mutation for Lymph Node Metastasis in Papillary Thyroid Cancer:A Meta-analysis

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Current Medical Science 2018年第5期38卷 785-797页

作者： Jing-yong SONG shi-ran SUN Fang DONG Tao HUANG Bin WU Jing ZHOU Department of Breast and Thyroid Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWukan 430022China Department of Gastrointestinal Surgery Hainan Cancer HospitalHaikou 570000China Department of Hepatobiliary Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Orthopaedics Surgery Union HospitalTongji Medical CollegeHuazhong University of Scienceand TechnologyWuhan 430022China

BRAF^V600E mutation has been thought to be a valuable molecular marker that may predict a worse prognosis for papillary thyroid cancer (PTC).But whether BRAF^V600E mutation is associated with lymph node metastasis (LNM)remains controversial. Different surgical strategies may bring a bias in demonsstrating the association between *** order to delineate a risk stratification to guide a tailored initial approach to tumors that express BRAF^V600E mutation,we performed this meta-analysis by using the articles in which total or near-total thyroidectomy plus bilateral central lymph node dissection was routinely performed to avoid the bias from the surgical *** searched the Medline,Embase and CNKI database for eligible studies from January 2003 to May ***-analysis was performed using the STATA 12.0 *** ratios (ORs)and 95% confidence intervals (CIs)were calculated under fixed-effects or random-effects *** clinical studies were included with a total of 4909 PTC patients. Our meta-analysis results reported that BRAF^V600E mutation was associated with LNM (OR=1.34;95% CI:1.09-1.65;P=0.005),as well as central LNM (OR=1.59;95% CI: 1.35-1.88;P<0.00001).Moreover,in patients with papillary thyroid microcarcinoma, we also confirmed the predictive value of BRAF^V600E mutation for LNM (OR=3.49;95% CI:2.02-6.02;P<0.00001).This meta-analysis demonstrates that BRAF^V600E mutation is closely related to LNM in PTC *** results suggest that BRAF^V600E mutation can be considered as a risk factor for LNM in ***,combining BRAF^V600E mutation with other risk factors to determine the initial surgical treatment may bring benefits for PTC patients.

关键词： B-Raf proto-oncogene thyroid cancer papillary thyroid carcinoma lymph node metastasis meta-analysis

A Note on Homoclinic or Heteroclinic Orbits for the Generalized Hénon Map

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Acta Mathematicae Applicatae Sinica 2016年第2期32卷 283-288页

作者： yong-guo shi College of Mathematics and Information Science Xinyang Normal UniversityXinyang 464000China Key Laboratory of Numerical Simulation of Sichuan Province College of Mathematics and Information ScienceNeijiang Normal UniversityNeijiang 641112China

An important problem in a given dynamical system is to determine the existence of a homoclinic orbit. We improve the results of Qin and Xiao [Nonlinearity, 20 （2007）, 2305-2317], who present some sufficient conditions for the existence of a homoclinic/heteroclinic orbit for the generalized H@non map. Moreover, an algorithm is presented to locate these homoclinic orbits.

关键词： reversible planar map homoclinic orbit heteroclinic orbit generalized Henon map

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Extremal P_(8)-Free/P_(9)-Free Planar Graphs

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Journal of the Operations Research Society of China 2023年第3期11卷 451-457页

作者： yong-Xin Lan yong-Tang shi School of Science Hebei University of TechnologyTianjin300401China Center for Combinatorics and LPMC Nankai UniversityTianjin300071China

An H-free graph is a graph not containing the given graph H as a *** is well known that the Turán number ex(n,H)is the maximum number of edges in an H-free graph on n *** on this definition,we define ex_(P)(n,H)to restrict the graph classes to planar graphs,that is,ex_(P)(n,H)=max{|E(G)|:G∈G,where G is a family of all H-free planar graphs on n ***,we have ex_(P)(n,H)=3n−6 if the graph H is not a planar *** study is initiated by Dowden(J Graph Theory 83:213–230,2016),who obtained some results when H is considered as C_(4)or C_(5).In this paper,we determine the values of ex_(P)(n,Pk)with k∈{8,9},where Pk is a path with k vertices.

关键词： Turán number Extremal graph Planar graph

额尔齐斯河流域不同土地利用区大型真菌资源分布调查

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新疆师范大学学报（自然科学版） 2025年第1期44卷 42-50页

作者：潘冉冉新疆师范大学生命科学学院、中亚区域跨境有害生物联合控制国际研究中心、新疆特殊环境物种保护与调控生物学实验室新疆乌鲁木齐830017

为探明额尔齐斯河流域大型真菌资源及分布,本研究采用访谈法、样方法以及样线法,分别于2022年6月至8月和2023年7月至8月对额尔齐斯河流域及周边主要耕地、自然草场、林区和食用菌种植区的大型真菌资源进行调查和监测。本研究在692个踏... 详细信息

为探明额尔齐斯河流域大型真菌资源及分布,本研究采用访谈法、样方法以及样线法,分别于2022年6月至8月和2023年7月至8月对额尔齐斯河流域及周边主要耕地、自然草场、林区和食用菌种植区的大型真菌资源进行调查和监测。本研究在692个踏查点中共采集大型真菌样本136份,经鉴定该区域有大型真菌2门2纲6目14科24属31种。其中鬼伞属(Coprinus)最丰富,有4种,占总物种数的12.90%;斑褶菇属(Panaeolus)次之,有3种,占总物种数的9.68%;侧耳属(Pleurotus)和丝膜菌属(Cortinarius)分别有2种,各占总物种数的6.45%;其余20属均仅有1种。调查发现,额尔齐斯河流域大型真菌资源在沿河流域的林地和草地分布较密集,在人为干扰环境,如建筑用地分布较少。此外,通过对大型真菌子实体生境因子监测发现,大型真菌子实体的分布与温度、湿度等环境因子相关,其中皱环球盖菇(Stropharia rugosoannulata)对环境的抗逆性强,可作为潜在食用栽培菌。本研究可为该地区大型真菌物种多样性、食用菌业育种开发等提供本底资源数据。

关键词：大型真菌资源生态功能空间分布环境因子

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Single-channel sampling and multi-channel reconstruction AIC via multiple chirp noise sequences

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Science China(Information Sciences) 2018年第10期61卷 263-265页

作者： Pengfei shi Hao HUAN ran TAO School of Information and Electronics Beijing Institute of Technology Beijing Key Laboratory of Fractional Signals and Systems Beijing Institute of Technology

Dear editor,As preliminary implementation of compressed sensing (CS), the analog-to-information converter(AIC) plays an important role in reducing the sampling rate of analog signals via PN sequence [1,2]. However, it suffers severe reconstruction errors (REs) when acquiring noisy signals prior to measurement in cases with low signal-noise ratio(SNR)[3].To damp the RE, the adaptive weighted norm constraint is first introduced in [4], which enables

关键词： AIC MCR SCS Single-channel sampling and multi-channel reconstruction AIC via multiple chirp noise sequences

Imperative for long-term management and surveillance in Kawasaki disease

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World Journal of Clinical Cases 2025年第4期13卷 61-63页

作者： Yan Pan Fu-yong Jiao Department of Pediatrics The First Affiliated Hospital of Yangtze UniversityJingzhou 434000Hubei ProvinceChina Shaanxi Kawasaki Disease Diagnosis and Treatment Center Children’s HospitalShaanxi Provincial People’s Hospital of Xi’an Jiaotong UniversityXi’an 710000Shaanxi ProvinceChina

Kawasaki disease(KD)is a significant pediatric vasculitis known for its potential to cause severe coronary artery *** the effectiveness of initial treatments,such as intravenous immunoglobulin,KD patients can experience long-term cardiovascular issues,as evidenced by a recent case report of an adult who suffered a ST-segment elevation myocardial infarction due to previous KD in the World Journal of Clinical *** editorial emphasizes the critical need for long-term management and regular surveillance to prevent such *** drawing on recent research and case studies,we advocate for a structured approach to follow-up care that includes routine cardiac evaluations and preventive measures.

关键词： Kawasaki disease Long-term management Coronary artery aneurysm Surveillance Preventive care

Microstructure of ZM6 magnesium alloy with different Nd content

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Rare Metals 2013年第3期32卷 234-240页

作者： Weng-yong shi Yan Ma College of Mechanical and Electrical Engineering Northeast Forestry University Harbin 150040 China Graduate School Harbin University of Science and TechnologyHarbin 150080 China

With the purpose of studying the influence of Nd on the alloy structure and castability of ZM6, under the fixed content of Zn and Zr, this paper observes and analyzes the microstructure morphology of ZM6 alloy fracture with dif- ferent Nd content by the means of uniaxial tension experiment and scanning electron microscope （SEM） observation. The search results indicate that the structure of ZM6 alloy after added Nd can be refined to some extent, while it has no obvious influence on the grain structure and dimension of as- ast ZM6 alloy. Through increasing the ratio between Nd and Zn, it turns out that Nd and Zn reduces their own solid solu- bility by each other in α-Mg, and meanwhile, they gather toward the grain boundary, which is beneficial to refine the structure of ZM6 alloy ingot and enables the grain dimension of ZM6 alloy to reach the minimum when the Nd content is 2.5 %. On the basis of the minimization of the grain dimen- sion, the tensile property of ZM6 alloy improves with the Nd content. Thus, it provides theoretical guidance and technical support for the improvement of ZM6 alloy structure.

关键词： ZM6 alloy Magnesium alloy Microstructure

Reductive leaching of manganese from low-grade pyrolusite ore in sulfuric acid using pyrolysis-pretreated sawdust as a reductant

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International Journal of Minerals,Metallurgy and Materials 2016年第3期23卷 241-246页

作者： Ya-li Feng shi-yuan Zhang Hao-ran Li School of Civil and Environmental Engineering University of Science and Technology Beijing National Key Laboratory of Biochemical Engineering Institute of Process Engineering Chinese Academy of Sciences

Manganese （Mn） leaching and recovery from low-grade pyrolusite ore were studied using sulfiaric acid （H2SO4） as a leachant and pyrolysis-pretreated sawdust as a reductant. The effects of the dosage of pyrolysis-pretreated sawdust to pyrolusite ore, the concentration of sulfuric acid, the liquid/solid ratio, the leaching temperature, and the leaching time on manganese and iron leaching efficiencies were inves- tigated. Analysis of manganese and iron leaching efficiencies revealed that a high manganese leaching efficiency was achieved with low iron extraction. The optimal leaching efficiency was determined to be 20wt% pyrolysis-pretreated sawdust and 3.0 mol/L H2SO4 using a liq- uid/solid ratio of 6.0 mL/g for 90min at 90℃. Other low-grade pyrolusite ores were tested, and the results showed that they responded well with manganese leaching efficiencies greater than 98%.

关键词： manganese ore treatment pyrolusite sawdust pyrolysis leaching manganese

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Unraveling the impacts of intermolecular interaction on morphology evolution for highly efficient organic solar cells and modules

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Science China Chemistry 2025年第01期 264-272页

作者： Xueqing Ma Yingying Cheng Yuqiang Liu Xinming Zheng Guangliu ran Hongxiang Li Xinyue Cui Andong Zhang Wenkai Zhang Pei Cheng Wenchao Huang Zhishan Bo Beijing Key Laboratory of Energy Conversion and Storage Materials College of Chemistry Beijing Normal University College of Textiles and Clothing State Key Laboratory of Bio-fibers and Eco-textiles Qingdao University Key State Laboratory of Advanced Technology for Materials Synthesis and Processing School of Materials Science and EngineeringWuhan University of Technology Department of Physics and Applied Optics Beijing Area Major Laboratory Center for Advanced Quantum Studies Beijing Normal University State Key Laboratory of Polymer Materials Engineering College of Polymer Science and Engineering Sichuan University

Understanding the effect of intermolecular interaction on the growth dynamic of active layers is critical for advancing organic solar cells(OSCs). However, the diverse structure of donors and acceptors makes the research challenging. Additives with customizable structures and properties could simplify this complexity. Herein, we meticulously tailor two additives of 3,4-ethylenedioxythiophene(EDOT) and 2,5-dibromo-3,4-ethylenedioxythiophene(DBEDOT), possessing distinct intermolecular interaction features to elaborate the inherent relationship. It is found that varied interaction strengths can alter film formation processes. The enhanced intermolecular interaction between the DBEDOT and non-fullerene acceptor BTP-e C9-4F results in pre-aggregation and longer crystallization duration of BTP-e C9-4F, facilitating the formation of films with compact molecular packing and decent phase separation. Thus, exciton dissociation and charge transport become more efficient. Finally, devices processed with DBEDOT exhibit a remarkable power conversion efficiency of 19.35% in small-area OSCs and 14.11% in bladecoated 5 cm × 5 cm organic solar mini-modules. Especially, OSCs can maintain 80% of their initial efficiency after continuous annealing at 85 °C for over 2,100 h.

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