检索结果-南通市图书馆

Celastrus orbiculatus Extract Inhibits Immune Inflammatory Thrombotic State of B-Lymphoma

Chinese Journal of Integrative Medicine 2024年第11期30卷 1018-1026页

作者： ZHU Miao shi Qing-qing NI Jun WU Wei SUN Xing SUN Mei XU Kai-lin LIU Yan-qing gu jian gu Hao Department of Hematology Clinical Medical CollegeYangzhou UniversityYangzhouJiangsu Province 225001China Yangzhou Institute of Hematology YangzhouJiangsu Province 225001China Department of Hematology The Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu Province 221000China Department of Oncology The Affiliated Hospitalof Yangzhou UniversityYangzhou UniversityYangzhouJiangsu Province 225001China Department of Neurology The Affiliated Brain Hospital of Nanjing Medical UniversityNanjing 210000China

Objective:To investigate the inhibitory effect of Celastrus orbiculatus extracts(COE)on the proliferation of lymphoma cells and the immune regulation ability on inflammation and thrombophilia in ***:The 38B9 lymphoma cells were treated with COE(160μg/mL)and CTX(25μmol/L).The apoptosis rate and cell cycle of each group were detected by flow *** secretion of inflammatory factors,including interleukin(IL)-6,IL-10,and tumor necrosis factorα(TNF-α),in cell supernatant was detected by enzyme-linked immunosorbent assay(ELISA).In vivo,BALB/c mice were subcutaneously injected with 38B9 lymphoma cells to establish lymphoma ***(3 mg·kg^(-1)·d^(-1))and CTX(40 mg·kg^(-1)·d^(-1))were administered to the model mice,*** expression of plasma inflammatory factors(IL-6,IL-10 and TNF-α)and thrombus indexes,including D-dimer(D-D),von Willebrand factor(vWF)and tissue factor(TF),were detected by ELISA before tumor bearing(1 d),after tumor formation(14 d)and after intervention(21 d).PicoGreen dsDNA was used to detect the level of serum neutrophil extracellular traps(NETs).Flow cytometry was used to detect the expression of platelet activation marker calcium-dependent lectin-like receptor 2(CLEC-2).The tumor growth and survival of mice were ***:The 38B9 lymphoma cells were apoptotic after the intervention of COE and *** ratio of G_(2)-M phase cells decreased in COE intervented cells compared with the control cells(P<0.05),and S phase cells decreased in CTX intervented cells(P<0.05).Also,the secretion level of IL-6 was significantly reduced after COE or CTX intervention(P<0.05),and IL-10 was significantly increased(P<0.05).Furthermore,the tumor mass was reduced,and the median survival time was longer in COE and CTX intervented tumor-bearing mice than in non-intervented *** significantly lower levels of TNF-α,IL-6,NETs,TF,DD and CLEC-2,as well as higher IL-10 were observed in COE and CTX treatment mice in comparision with the control

关键词： Celastrus orbiculatus extract murine lymphoma cells tumor inflammation thrombotic state immune regulation proliferation inhibition lymphoma

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High Manganese Steel Alloying Process and Its Influence on Microstructure and Properties of the Steel

引用

Journal of Materials Science & Technology 1995年第2期11卷 102-108页

作者： shi, ZL gu, MY LIU, JY YIN, YS HEBEI INST MECH ELECT DEPT MAT SCI & ENGNSHIJIAZHUANGPEOPLES R CHINA DALIAN UNIV TECHNOL DEPT MAT SCI & ENGNDALIAN 116023PEOPLES R CHINA

The influence of two kinds of alloying processes, adding Nb (or Ti) and N-Mn alloy as well as adding Nb (or Ti) and spraying Nz, on microstructures and properties of a high manganese steel has been studied. It has been found that adding Nb(or Ti), accompanying with N-Mn alloy, is unfavourable to microstructure compactness of the high manganese steel, but adding Nb (or Ti) and spraying N-2 into the melt is good for refining austenitic grain, forming a lot of hard particles and improving microstructure compactness. The mechanical properties of the high manganese steel have relation to the content of elements Nb or Ti. Its fracture mode will turn ductile fracture into brittle cleavage fracture gradually By X-ray and TEM analysis, it is proved that the austenite can be transformed to deformation-induced cr martensite after adding a certain amount of element Nb (or Ti). The microstructure transformation of alloying high manganese steels through deformation is one of methods for strengthening austenite matrix acid increasing the work-hardening rate as well as improving antiwear property.

关键词： Alloying

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Superconducting Single-Layer T-Graphene and Novel Synthesis Routes

引用

Chinese Physics Letters 2019年第9期36卷 46-63页

作者： Qinyan gu Dingyu Xing jian Sun National Laboratory of Solid State Microstructures School of Physics and Collaborative Innovation Center of Ad vanced MicrostructuresNanjing UniversityNanjing 210093

Single-layer superconductors are ideal materials for fabricating superconducting nano ***,up to date,very few single-layer elemental superconductors have been predicted and especially no one has been successfully synthesized ***,using crystal structure search techniques and ab initio calculations,we predict that a single-layer planar carbon sheet with 4-and 8-membered rings called T-graphene is a new intrinsic elemental superconductor with superconducting critical temperature(Tc)up to around 20.8 *** importantly,we propose a synthesis route to obtain such a single-layer T-graphene,that is,a T-graphene potassium intercalation compound(C4 K with P4/mmm symmetry)is firstly synthesized at high pressure(>11.5 GPa)and then quenched to ambient condition;and finally,the single-layer T-graphene can be either exfoliated using the electrochemical method from the bulk C4 K,or peeled off from bulk T-graphite C4,where C4 can be obtained from C4 K by evaporating the K ***,we find that the calculated Tc of C4 K is about 30.4 K at 0 GPa,which sets a new record for layered carbon-based *** present findings add a new class of carbon-based *** particular,once the single-layer T-graphene is synthesized,it can pave the way for fabricating superconducting devices together with other 2 D materials using the layer-by-layer growth techniques.

关键词： red Superconducting Single-Layer T-Graphene and Novel Synthesis Routes Graphene

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

PREDICTION OF VORTEX-INDUCED VIBRATION OF LONG FLEXIBLE CYLINDERS MODELED BY A COUPLED NONLINEAR OSCILLATOR:INTEGRAL TRANSFORM SOLUTION

引用

Journal of Hydrodynamics 2012年第6期24卷 888-898页

作者： gu Ji-jun AN Chen LEVI Carlos SU jian Ocean Engineering Program COPPEUniversidade Federal do Rio de Janeiro Nuclear Engineering Program COPPEUniversidade Federal do Rio de Janeiro

The Generalized Integral Transform Technique （GITT） was applied to predict dynamic response of Vortex-Induced Vibration （VIV） of a long flexible cylinder. A nonlinear wake oscillator model was used to represent the cross-flow force acting on the cylinder, leading to a coupled system of second-order Partial Differential Equations （PDEs） in temporal variable. The GITT approach was used to transform the system of PDEs to a system of Ordinary Differential Equations （ODEs）, which was numerically solved by using the Adams-Moulton and Gear method （DIVPAG） developed by the International Mathematics and Statistics Library （IMSL）. Numerical results were presented for comparison to those given by the finite difference method and experimental results, allowing a critical evaluation of the technique performance. The influence of variation of mean axial tension induced by elongation of flexible cylinder was evaluated, which was shown to be not negligible in numerical simulation of VIV of a long flexible cylinder.

关键词： Vortex-Induced Vibration (VIV) nonlinear wake oscillator flexible cylinder integral transform

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Influence of construction interfaces on dynamic characteristics of roller compacted concrete dams

引用

Journal of Central South University 2015年第4期22卷 1521-1535页

作者： gu Chong-shi WANG Shao-wei BAO Teng-fei State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Hohai University National Engineering Research Center of Water Resources Efficient Utilization and Engineering Safety Hohai University College of Water-Conservancy and Hydropower Hohai University

To study the influence of construction interfaces on dynamic characteristics of roller compacted concrete dams(RCCDs),mechanical properties of construction interfaces are firstly analyzed. Then, the viscous-spring artificial boundary(VSAB) is adopted to simulate the radiation damping of their infinite foundations, and based on the Marc software, a simplified seismic motion input method is presented by the equivalent nodal loads. Finally, based on the practical engineering of a RCC gravity dam, effects of radiation damping and construction interfaces on the dynamic characteristics of dams are investigated in detail. Analysis results show that dynamic response of the RCC gravity dam significantly reduces about 25% when the radiation damping of infinite foundation is considered. Hot interfaces and the normal cold interfaces have little influence on the dynamic response of the RCC gravity ***, nonlinear fracture along the cold interfaces at the dam heel will occur under the designed earthquake if the cold interfaces are combined poorly. Therefore, to avoid the fractures along the construction interfaces under the potential super earthquakes,combination quality of the RCC layers should be significantly ensured.

关键词： roller compacted concrete dam construction interface nonlinear fracture radiation damping viscous-spring artificial boundary dynamic response

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fault detection for sector-bounded non-linear systems with servo inputs and sensor stuck faults

引用

Journal of Control and Decision 2019年第3期6卷 147-165页

作者： Ying gu Xiao-jian Li School of Science Dalian Jiaotong UniversityDalianChina College of Information Science and Engineering Northeastern UniversityShenyangChina State Key Laboratory of Synthetical Automation of Process Industries Northeastern UniversityShenyangChina

This paper addresses the fault detection(FD)problem for discretetime sector-bounded non-linear systems with finite-frequency servo *** non-linear systems are firstly modelled as *** main contributions are that a novel FD filter which combines the finite-frequency H∞and H−indices is *** from the existing methods,the proposed FD scheme guarantees that the generated residuals are robust against the servo inputs in fault-free case and sensitive to them in faulty ***,the small sensor stuck faults including outagefaults can be *** this class of systems,the existing finite-frequency FD filter design methods are invalid.A new lemma is developed to characterise the system performances in finite-frequency *** addition,sufficient conditions for the existence of such a FD filter are derived by introducing slack variable and linear matrix inequalities ***,an example is presented to demonstrate the method and its effectiveness.

关键词： Fault detection servo inputs sensor stuck faults sector-bounded nonlinearity finite-frequency domain

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applying a global pulse disturbance to eliminate spiral waves in models of cardiac muscle

引用

Chinese Physics B 2021年第7期30卷 157-162页

作者： jian Gao Changgui gu Huijie Yang Business School University of Shanghai for Science and TechnologyShanghai 200093China

Removal of spiral waves in cardiac muscle is necessary because of their threat to *** methods for this removal are to apply a local disturbance to the media,such as a periodic ***,most of these methods accelerate the beating of the cardiac muscle,resulting in the aggravation of the ventricular tachycardia,which directly threatens *** the present study,in order to clear off spiral waves,a global pulse-disturbance is applied to the media based on three models of cardiac *** is found that the spiral waves are eliminated and the frequency of the cardiac muscle is decreased in a short time,and finally,the state of the medium reaches the normal oscillation,which supports a target *** method sheds light on the removal of spiral waves in cardiac muscle and can prevent the ventricular tachycardia as well as the ventricular fibrillation.

关键词： ventricular fibrillation spiral wave pattern formation elimination

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Notes on Application of WKB Method

引用

Communications in Theoretical Physics 2008年第10期50卷 864-866页

作者： gu Xiao-Yan SUN jian-Qiang Department of Physics East China University of Science and Technology Shanghai 200237 China Institute of Applied Physics and Computational Mathematics Beijing 100088 China

The notes here presented are of the modifications introduced in the application of WKB *** of two-and three-dimensional harmonic oscillator potential are revisited by WKB and the new formulationof quantization rule *** is found that the energy spectrum of the radial harmonic oscillator,which isreproduced exactly by the standard WKB method with the Langer modification,is also reproduced exactly without theLanger modification via the new quantization rule *** alternative way to obtain the non-integral Maslov indexfor three-dimensional harmonic oscillator is proposed.

关键词： WKB method quantization rules harmonic oscillator two-dimensional space

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of Atomic Mixing in Inertial Confinement Fusion by Multifluid Interpenetration Mix Model

引用

Communications in Theoretical Physics 2009年第12期52卷 1102-1106页

作者： gu jian-Fa YE Wen-Hua Institute of Applied Physics and Computational Mathematics Beijing 100094 China

The effects of atomic-level rnixing are systemically investigated in a multifluid interpenetration mix model ,and results are compared with the single-fluid model＇s simulations and experimental data. It is shown that increasing the model free parameter α, shock Mach number, and the initial density discontinuity makes the mix length and fraction of mixing particle increase, resulting in the lower shock temperatures compared with the results of single-fluid model without mixing. Recent high-compressibility direct-drive spherical implosions on OMEGA are simulated by the interpenetration mix modal. The calculations with atomic mixing between fuel and shell match quite well with the observations. Without considering any mixing, the calculated neutron yields and ion temperatures are overpredicted; while inclusion of the interpenetration mix model with the adjustable parameter α could fit the simulated neutron yields and ion temperatures well with experimental data.

关键词： multifluid interpenetration mix model atomic mixing inertial confinement fusion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Synthesis of Dialdehyde from Sodium Hydrogen Telluride with 1,1',3,3'-Tetramethyl-2,2'-bis-benzimidazolium Salt

引用

Chinese Chemical Letters 2002年第9期13卷 836-838页

作者： Yue, KF gu, H shi, Z Northwest Univ Dept Chem Xian 710069 Peoples R China

The reaction of bis-benzimidazolium salts with sodium hydrogen telluride is reported, and a new synthetic method for dialdehydes is provided.

关键词： Bis-benzimidazolium salt sodium hydrogen telluride dialdehyde synthesis.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：