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Sensitivity of Sample for Simulation-Based Reliability Analysis Methods

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Computer Modeling in Engineering & Sciences 2021年第1期126卷 331-357页

作者： Xiukai Yuan jian gu Shaolong Liu School of Aerospace and Engineering Xiamen UniversityXiamen361005China Institute for Risk and Reliability Leibniz Universitat HannoverHannoverGermany

In structural reliability analysis,simulation methods are widely *** statistical characteristics of failure probability estimate of these methods have been well *** this study,the sensitivities of the failure probability estimate and its statistical characteristics with regard to sample,called‘contribution indexes’,are proposed to measure the contribution of *** contribution indexes in four widely simulation methods,i.e.,Monte Carlo simulation(MCS),importance sampling(IS),line sampling(LS)and subset simulation(SS)are derived and *** proposed contribution indexes of sample can provide valuable information understanding the methods deeply,and enlighten potential improvement of *** is found that the main differences between these investigated methods lie in the contribution indexes of the safety samples,which are the main factors to the efficiency of the ***,numerical examples are used to validate these findings.

关键词： Reliability analysis Monte Carlo simulation importance sampling line sampling subset simulation

Carbon-coated Ni-Co alloy catalysts:preparation and performance for in-situ aqueous phase hydrodeoxygenation of methyl palmitate to hydrocarbons using methanol as the hydrogen donor

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Frontiers of Chemical Science and Engineering 2022年第4期16卷 443-460页

作者： Yinteng shi Lin Ai Haonan shi Xiaoyu gu Yujun Han Jixiang Chen Tianjin Key Laboratory of Applied Catalysis Science and Technology Department of Catalysis Science and EngineeringSchool of Chemical Engineering and TechnologyTianjin UniversityTianjin 300350China

Carbon-coated Ni,Co and Ni-Co alloy catalysts were prepared by the carbonization of the metal doped resorcinol-formaldehyde resins synthesized by the one-pot extended Stöber *** was found that the introduction of Co remarkably reduced the carbon microsphere *** metallic Ni,Co,and Ni-Co alloy particles(mainly 10-12 nm)were uniformly distributed in carbon microspheres.A charge transfer from Ni to Co appeared in the Ni-Co *** with those of metallic Ni and Co,the d-band center of the Ni-Co alloy shifted away from and toward the Fermi level,*** the in-situ aqueous phase hydrodeoxygenation of methyl palmitate with methanol as the hydrogen donor at 330℃,the decarbonylation/decarboxylation pathway dominated on all *** Ni-Co@C catalysts gave higher activity than the Ni@C and Co@C catalysts,and the yields of n-pentadecane and n-C6-n-C16 reached 71.6%and 92.6%,*** excellent performance of Ni-Co@C is attributed to the electronic interactions between Ni and Co and the small carbon *** to the confinement effect of carbon,the metal particles showed high resistance to sintering under harsh hydrothermal *** deactivation is due to the carbonaceous deposition,and the regeneration with CO_(2) recovered the catalyst reactivity.

关键词： Stöber method carbon-coated Ni-Co alloy in-situ hydrodeoxygenation methyl palmitate decarbonylation decarboxylation

基于度量学习理论的马田系统改进及其应用研究

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管理工程学报 2025年第2期39卷 221-233页

作者：常志朋顾玉萍陈闻鹤安徽工业大学商学院安徽工业大学复杂系统多学科管理与控制安徽普通高校重点实验室安徽财经大学管理科学与工程学院南京理工大学经济管理学院

为提升马田系统的识别性能,本文利用度量学习理论对其进行改进。一是将传统协方差马氏距离改进为以度量矩阵为参变量的马氏距离函数,然后利用简单直接的KISSME度量学习算法估计一个最能反映数据间内在关系的度量矩阵,该度量矩阵可以使... 详细信息

为提升马田系统的识别性能,本文利用度量学习理论对其进行改进。一是将传统协方差马氏距离改进为以度量矩阵为参变量的马氏距离函数,然后利用简单直接的KISSME度量学习算法估计一个最能反映数据间内在关系的度量矩阵,该度量矩阵可以使同类样本更紧凑、非同类样本更分离,这有助于提升马田系统的识别性能。二是基于拉近同类样本、推远非同类样本的思想,定义一个新的特征子集评估函数代替田口方法中的信噪比,这有助于筛选出可以提高马田系统识别性能的特征。改进后的马田系统仍然保持了原理简单、易于操作的优势。本文选取6个UCI数据集进行验证,得出改进后的马田系统在Accuracy、Specificity、G-means和降维率等方面均明显优于传统马田系统的结论。最后,本文通过返贫识别验证了改进后马田系统的可行性和有效性。

关键词：马田系统度量学习 KISSME 返贫识别

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Incorporation of a Toll-like receptor 2/6 agonist potentiates mRNA vaccines against cancer and infectious diseases

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Signal Transduction and Targeted Therapy 2023年第8期8卷 3806-3817页

作者： Yangzhuo gu Jingyun Yang Cai He Tingmei Zhao Ran Lu jian Liu Xianming Mo Fuqiang Wen Huashan shi Department of Biotherapy State Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan Universityand Collaborative Innovation Center for BiotherapyChengduSichuan 610041China Division of Pulmonary Diseases State Key Laboratory of Biotherapy and Department of Respiratory and Critical Care MedicineWest China HospitalSichuan UniversityChengduSichuan 610041China Laboratory of Stem Cell Biology and Department of Pediatric Surgery State Key Laboratory of BiotherapyWest China HospitalSichuan Universityand Collaborative Innovation Center for BiotherapyChengduSichuan 610041China

mRNA vaccines have emerged rapidly in recent years as a prophylactic and therapeutic agent against various diseases including cancer and infectious *** of mRNA vaccines have been underway,among which boosting of efficacy is of great ***2Cys,a simple synthetic metabolizable lipoamino acid that signals through Toll-like receptor(TLR)2/6 pathway,eliciting both humoral and cellular adaptive immune responses,is an interesting candidate *** investigate the enhancement of the efficacies of mRNA vaccines by Pam2Cys,the adjuvant was incorporated into mRNA-lipid nanoparticles(LNPs)to achieve co-delivery with *** with the resulting mRNA-LNPs(Pam2Cys)shaped up the immune milieu in the draining lymph nodes(dLNs)through the induction of IL-12 and IL-17,among other *** presentation was carried out mainly by migratory and dLNresident conventional type 2 DCs(cDC2s)and significantly more potent antitumor responses were triggered in both prophylactic and therapeutic tumor models in a CD4^(+) and CD8^(+) T cell-dependent *** memory antitumor immunity was also ***,the vaccine also stimulated much more robust humoral and cellular immunity in a surrogate COVID-19 prophylactic *** but not the least,the new vaccines exhibited good preliminary safety profiles in murine *** facts warrant future development of Pam2Cys-incorporated mRNA vaccines or relevant mRNA therapeutics for clinical application.

关键词： vaccines immunity diseases

Styrene epoxidation with hydrogen peroxide over calcium oxide catalysts prepared from various precursors

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Journal of Natural Gas Chemistry 2012年第4期21卷 452-458页

作者： Qingming gu Dan Han Lei shi Qi Sun Institute of Chemistry for Functionalized Materials Faculty of Chemistry and Chemical EngineeringLiaoning Normal UniversityDalian 116029LiaoningChina

A series of CaO samples were prepared by calcination of commercially available and synthesis of calcium salt precursors such as calcium acetate, carbonate, hydroxide and oxalate etc. CaO samples were found to be effective for the epoxidation of styrene using hydrogen peroxide as an oxidant in the presence of acetonitrile. To determine the influence of the physicochemical properties and surface basicity on the catalytic activity, the prepared CaO samples were characterized using thermogravimetry （TG）, X-ray diffraction （XRD）, scanning electron microscopy （SEM）, N2-adsorption and temperature-programmed desorption of CO2 （CO2-TPD）. The results indicate that the amounts of very strong basic sites and high basicity strength on CaO sample are key factors for its excellent catalytic performance. In contrast, the surface area, porosity and the surface structure of CaO sample have a relatively minor effect on the catalytic activity. CaO sample, obtained by the decomposition of Ca（OH）2, prepared by precipitating calcium nitrate with sodium hydroxide in ethylene glycol solution, exhibits the highest amount of very strong basic sites and stronger strength of basic sites, and therefore it catalyses the epoxidation of styrene with the highest rate among the tested CaO samples. Under the selected reaction conditions, the selectivity of 97.5% to styrene oxide at a conversion in excess of 99% could be obtained.

关键词： epoxidation styrene calcium oxide hydrogen peroxide surface basicity

Synthesis of flexible inter-plant heat exchanger networks: A decomposition method considering intermedium fluid circles

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CHINESE JOURNAL OF CHEMICAL ENGINEERING 2024年第11期75卷 62-73页

作者： Tao, Ran gu, Siwen Liu, Linlin Du, jian Dalian Univ Technol Sch Chem Engn Inst Proc Syst Engn Dalian 116023 Peoples R China Changzhou Inst Technol Sch Photoelect Engn Changzhou 213032 Peoples R China

The traditional methods for synthesizing flexible heat exchanger networks (HENs) are not directly applicable to inter-plant HEN challenges, primarily due to the spread of system uncertainty across plants via intermedium fluid circles. This complicates the synthesis process significantly. To tackle this issue, this study proposes a decomposed stepwise methodology to facilitate the flexible synthesis of the interplant HENs performing indirect heat integration. A decomposition strategy is proposed to divide the overall network into manageable sub-networks by dissecting the intermedium fluid circles. To address the variability in intermedium fluid temperatures, a temperature fluctuation analysis approach is developed and a heuristic rule is introduced to maintain the temperature feasibility of the intermedium fluids. To ensure adequate flexibility and cost-effectiveness of the designed networks, flexibility analysis and network retrofit steps are conducted through model-based optimization techniques. The efficacy of the method is demonstrated through two case studies, showing its potential in achieving the desired operational flexibility for inter-plant HENs. (c) 2024 The Chemical Industry and Engineering Society of China, and Chemical Industry Press Co., Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

关键词： Inter-plant heat exchanger networks (HENs) Indirect heat integration Flexible synthesis Flexible analysis Decomposition method

Seismic performance evaluation of steel frame-steel plate shear walls system based on the capacity spectrum method

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第3期9卷 322-329页

作者： jian-hua SHAO Qiang gu Yong-kang SHEN College of Civil Engineering Hohai University Nanjing 210098 China Department of Civil Engineering Suzhou University of Science and Technology Suzhou 215011 China

This paper presents some methods that the standard acceleration design response spectra derived from the present China code for seismic design of buildings are transformed into the seismic demand spectra, and that the base shear force-roof displacement curve of structure is converted to the capacity spectrum of an equivalent single-degree-of-freedom （SDOF） system. The capacity spectrum method （CSM） is programmed by means of MATLABT.0 computer language. A dual lateral force resisting system of 10-story steel frame-steel plate shear walls （SPSW） is designed according to the corresponding China design codes. The base shear force-roof displacement curve of structure subjected to the monotonic increasing lateral inverse triangular load is obtained by applying the equivalent strip model to stimulate SPSW and by using the finite element analysis software SAP2000 to make Pushover analysis. The seismic performance of this dual system subjected to three different conditions, i.e. the 8-intensity frequently occurred earthquake, fortification earthquake and seldom occurred earthquake, is evaluated by CSM program. The excessive safety of steel frame-SPSW system designed according to the present China design codes is pointed out and a new design method is suggested.

关键词： Steel frame-steel plate shear walls (SPSW) system Capacity spectrum method (CSM) Seismic demand spectrum Base shear force-roof displacement Seismic performance evaluation

Cryptanalysis of Key Exchange Protocol Based on Tensor Ergodic Problem

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China Communications 2018年第10期15卷 172-181页

作者： Chunsheng gu Youyu gu Peizhong shi Chunpeng Ge Zhenjun Jing School of Computer Engineering Jiangsu University of Technology State Key Laboratory of Information Security Institute of Information Engineering Chinese Academy of Sciences School of Mathematics Hefei University of Technology

Recently, Mao, Zhang, Wu et al. constructed two key exchange(KE) protocols based on tensor ergodic problem(TEP). Although they conjectured that these constructions can potentially resist quantum computing attack, they did not provide a rigorous security proof for their KE protocols. In this paper, applying the properties of ergodic matrix, we first present a polynomial time algorithm to solve the TEP problem using O(n^6) arithmetic operations in the finite field, where n is the security parameter. Then, applying this polynomial time algorithm, we generate a common shared key for two TEP-based KE constructions, respectively. In addition, we also provide a polynomial time algorithm with O(n^6) arithmetic operations that directly recovers the plaintext from a ciphertext for the KE-based encryption scheme. Thus, the TEP-based KE protocols and their corresponding encryption schemes are insecure.

关键词： key exchange KE-based encryption tensor decomposition ergodic matrix

Three-stage aged refuse biofilter for the treatment of landfill leachate

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Journal of Environmental Sciences 2009年第1期21卷 70-75页

作者： LI Hongjiang ZHAO Youcai shi Lei gu Yingying State Key Laboratory of Pollution Control and Resources Reuse College of Environmental Science and Engineering Tonggji University Shanghai 200092 China. Department of Civil Engineering The University of Hong Kong Pokfulam Road 999077 Hong Kong China

A field-scale aged refuse （AR） biofilter constructed in Shanghai Refuse Landfill, containing about 7000 m^3 aged refuse inside, was evaluated for its performance in the treatment of landfill leachate. This AR biofilter can be divided into three stages and can manage 50 m^3 landfill leachate per day. The physical, chemical, and biological characteristics of AR were analyzed for evaluating the AR biofilter as leachate treatment host. The results revealed that over 87.8%-96.2% of COD and 96.9%-99.4% of ammonia nitrogen were removed by the three-stage AR biofilter when the infiuent leachate COD and ammonia nitrogen concentration were in the range 5478-10842 mg/L and 811-1582 mg/L, respectively. The final effluent was inodorous and pale yellow with COD and ammonia nitrogen below 267-1020 mg/L and 6-45 mg/L, respectively. The three-stage AR biofilter had efficient nitrification but relative poor denitrification capacity with a total nitrogen （TN） removal of 58%-73%. The external temperature of AR biofilter did not influence the total ammonia nitrogen removal significantly. It was concluded that the scale-up AR biofilter can work very well and can be a promising technology for the treatment of landfill leachate.

关键词： aged refuse biofilter landfill leachate COD ammonia nitrogen